Compile Data Set for Download or QSAR

Found 17 hits of non-affinity data for polymerid = 1266,1610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15026 (N-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-yl}py...) Show SMILES N[C@H](COc1cncc(NC(=O)c2cccnc2)c1)Cc1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c21-17(9-15-5-2-1-3-6-15)14-26-19-10-18(12-23-13-19)24-20(25)16-7-4-8-22-11-16/h1-8,10-13,17H,9,14,21H2,(H,24,25)/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15109 (3-[(2S)-2-amino-3-phenylpropoxy]-4-[(E)-2-(pyridin...) Show SMILES N[C@H](COc1cnccc1\C=C\c1ccncc1)Cc1ccccc1 |r| Show InChI InChI=1S/C21H21N3O/c22-20(14-18-4-2-1-3-5-18)16-25-21-15-24-13-10-19(21)7-6-17-8-11-23-12-9-17/h1-13,15,20H,14,16,22H2/b7-6+/t20-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15028 (5-[(2S)-2-amino-3-phenylpropoxy]-N-(pyridin-3-ylme...) Show SMILES N[C@H](COc1cncc(NCc2cccnc2)c1)Cc1ccccc1 |r| Show InChI InChI=1S/C20H22N4O/c21-18(9-16-5-2-1-3-6-16)15-25-20-10-19(13-23-14-20)24-12-17-7-4-8-22-11-17/h1-8,10-11,13-14,18,24H,9,12,15,21H2/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15029 (3-[(2S)-2-amino-3-({5-[2-(pyridin-4-yl)phenyl]pyri...) Show SMILES N[C@H](COc1cncc(c1)-c1ccccc1-c1ccncc1)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C27H24N4O/c28-22(13-20-16-31-27-8-4-3-7-26(20)27)18-32-23-14-21(15-30-17-23)25-6-2-1-5-24(25)19-9-11-29-12-10-19/h1-12,14-17,22,31H,13,18,28H2/t22-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15041 (3-[(2S)-2-amino-3-{[5-(4-nitrophenyl)pyridin-3-yl]...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc(cc1)N(=O)=O)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C22H20N4O3/c23-18(9-17-12-25-22-4-2-1-3-21(17)22)14-29-20-10-16(11-24-13-20)15-5-7-19(8-6-15)26(27)28/h1-8,10-13,18,25H,9,14,23H2/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15045 (4-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc(cc1)C(N)=N)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C23H23N5O/c24-19(9-18-12-28-22-4-2-1-3-21(18)22)14-29-20-10-17(11-27-13-20)15-5-7-16(8-6-15)23(25)26/h1-8,10-13,19,28H,9,14,24H2,(H3,25,26)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15046 (4-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc(cc1)C(=N)NO)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C23H23N5O2/c24-19(9-18-12-27-22-4-2-1-3-21(18)22)14-30-20-10-17(11-26-13-20)15-5-7-16(8-6-15)23(25)28-29/h1-8,10-13,19,27,29H,9,14,24H2,(H2,25,28)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15047 (4-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc(cc1)S(N)(=O)=O)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C22H22N4O3S/c23-18(9-17-12-26-22-4-2-1-3-21(17)22)14-29-19-10-16(11-25-13-19)15-5-7-20(8-6-15)30(24,27)28/h1-8,10-13,18,26H,9,14,23H2,(H2,24,27,28)/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15048 (3-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...) Show SMILES N[C@H](COc1cncc(c1)-c1cccc(c1)S(N)(=O)=O)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C22H22N4O3S/c23-18(8-17-12-26-22-7-2-1-6-21(17)22)14-29-19-9-16(11-25-13-19)15-4-3-5-20(10-15)30(24,27)28/h1-7,9-13,18,26H,8,14,23H2,(H2,24,27,28)/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15052 (N-[(4-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]py...) Show SMILES CC(=O)NCc1ccc(cc1)-c1cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c1 |r| Show InChI InChI=1S/C25H26N4O2/c1-17(30)28-12-18-6-8-19(9-7-18)20-11-23(15-27-13-20)31-16-22(26)10-21-14-29-25-5-3-2-4-24(21)25/h2-9,11,13-15,22,29H,10,12,16,26H2,1H3,(H,28,30)/t22-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15073 ((2R)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl]py...) Show SMILES N[C@H](COc1cncc(\C=C\c2ccncc2)c1)C(O)=O |r| Show InChI InChI=1S/C15H15N3O3/c16-14(15(19)20)10-21-13-7-12(8-18-9-13)2-1-11-3-5-17-6-4-11/h1-9,14H,10,16H2,(H,19,20)/b2-1+/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15080 ((2R)-2-amino-N-(naphthalen-2-yl)-3-({5-[(E)-2-(pyr...) Show SMILES N[C@H](COc1cncc(\C=C\c2ccncc2)c1)C(=O)Nc1ccc2ccccc2c1 |r| Show InChI InChI=1S/C25H22N4O2/c26-24(25(30)29-22-8-7-20-3-1-2-4-21(20)14-22)17-31-23-13-19(15-28-16-23)6-5-18-9-11-27-12-10-18/h1-16,24H,17,26H2,(H,29,30)/b6-5+/t24-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15099 ((2S)-2-amino-3-(1H-imidazol-5-yl)-N-{5-[(E)-2-(pyr...) Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)Nc1cncc(C=Cc2ccncc2)c1 |r,w:17.18| Show InChI InChI=1S/C18H18N6O/c19-17(8-15-10-22-12-23-15)18(25)24-16-7-14(9-21-11-16)2-1-13-3-5-20-6-4-13/h1-7,9-12,17H,8,19H2,(H,22,23)(H,24,25)/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15105 (3-[(2S)-2-amino-3-({5-[(E)-2-phenylethenyl]pyridin...) Show SMILES N[C@H](COc1cncc(\C=C\c2ccccc2)c1)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C24H23N3O/c25-21(13-20-15-27-24-9-5-4-8-23(20)24)17-28-22-12-19(14-26-16-22)11-10-18-6-2-1-3-7-18/h1-12,14-16,21,27H,13,17,25H2/b11-10+/t21-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15106 (3-[(2S)-2-amino-3-{3-[(E)-2-(pyridin-4-yl)ethenyl]...) Show SMILES N[C@H](COc1cccc(\C=C\c2ccncc2)c1)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C24H23N3O/c25-21(15-20-16-27-24-7-2-1-6-23(20)24)17-28-22-5-3-4-19(14-22)9-8-18-10-12-26-13-11-18/h1-14,16,21,27H,15,17,25H2/b9-8+/t21-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15107 (3-[(2S)-2-amino-3-({4-[(E)-2-(pyridin-4-yl)ethenyl...) Show SMILES N[C@H](COc1cc(\C=C\c2ccncc2)ccn1)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C23H22N4O/c24-20(14-19-15-27-22-4-2-1-3-21(19)22)16-28-23-13-18(9-12-26-23)6-5-17-7-10-25-11-8-17/h1-13,15,20,27H,14,16,24H2/b6-5+/t20-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 1679-85 (2006) Article DOI: 10.1016/j.bmcl.2005.12.017 BindingDB Entry DOI: 10.7270/Q23F4MWN
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15027 (5-[(2S)-2-amino-3-phenylpropoxy]-N-(pyridin-4-ylme...) Show SMILES N[C@H](COc1cncc(NCc2ccncc2)c1)Cc1ccccc1 |r| Show InChI InChI=1S/C20H22N4O/c21-18(10-16-4-2-1-3-5-16)15-25-20-11-19(13-23-14-20)24-12-17-6-8-22-9-7-17/h1-9,11,13-14,18,24H,10,12,15,21H2/t18-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 2000-7 (2006) Article DOI: 10.1016/j.bmcl.2005.12.065 BindingDB Entry DOI: 10.7270/Q2765CKX
					More data for this Ligand-Target Pair