Compile Data Set for Download or QSAR

Found 10 hits of non-affinity data for polymerid = 1406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29842 (N-(Pyridin-2-yl) arylsulfonamide, 2) Show SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)N2CCOCC2)n1 Show InChI InChI=1S/C18H20ClN3O4S/c1-13-15(19)5-3-6-16(13)27(24,25)21-17-7-2-4-14(20-17)12-18(23)22-8-10-26-11-9-22/h2-7H,8-12H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29844 (N-(Pyridin-2-yl) arylsulfonamide, 4) Show SMILES CN1CCN(CC1)C(=O)Cc1cccc(NS(=O)(=O)c2cccc(Cl)c2C)n1 Show InChI InChI=1S/C19H23ClN4O3S/c1-14-16(20)6-4-7-17(14)28(26,27)22-18-8-3-5-15(21-18)13-19(25)24-11-9-23(2)10-12-24/h3-8H,9-13H2,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29845 (N-(Pyridin-2-yl) arylsulfonamide, 5) Show SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)N2CCSCC2)n1 Show InChI InChI=1S/C18H20ClN3O3S2/c1-13-15(19)5-3-6-16(13)27(24,25)21-17-7-2-4-14(20-17)12-18(23)22-8-10-26-11-9-22/h2-7H,8-12H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29846 (N-(Pyridin-2-yl) arylsulfonamide, 6) Show SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)N2CCN(Cc3ccccc3)CC2)n1 Show InChI InChI=1S/C25H27ClN4O3S/c1-19-22(26)10-6-11-23(19)34(32,33)28-24-12-5-9-21(27-24)17-25(31)30-15-13-29(14-16-30)18-20-7-3-2-4-8-20/h2-12H,13-18H2,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29855 (N-(Pyridin-2-yl) arylsulfonamide, 17) Show SMILES Cc1cccc(NS(=O)(=O)c2cccc3ccccc23)n1 Show InChI InChI=1S/C16H14N2O2S/c1-12-6-4-11-16(17-12)18-21(19,20)15-10-5-8-13-7-2-3-9-14(13)15/h2-11H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29848 (N-(Pyridin-2-yl) arylsulfonamide, 8) Show SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(O)=O)n1 Show InChI InChI=1S/C14H13ClN2O4S/c1-9-11(15)5-3-6-12(9)22(20,21)17-13-7-2-4-10(16-13)8-14(18)19/h2-7H,8H2,1H3,(H,16,17)(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29851 (N-(Pyridin-2-yl) arylsulfonamide, 13) Show SMILES Cc1cccc(NS(=O)(=O)c2ccccc2C(F)(F)F)n1 Show InChI InChI=1S/C13H11F3N2O2S/c1-9-5-4-8-12(17-9)18-21(19,20)11-7-3-2-6-10(11)13(14,15)16/h2-8H,1H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29852 (N-(Pyridin-2-yl) arylsulfonamide, 14) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc(C)n1 Show InChI InChI=1S/C13H14N2O3S/c1-10-4-3-5-13(14-10)15-19(16,17)12-8-6-11(18-2)7-9-12/h3-9H,1-2H3,(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29853 (N-(Pyridin-2-yl) arylsulfonamide, 15) Show SMILES Cc1cccc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)n1 Show InChI InChI=1S/C16H20N2O2S/c1-12-6-5-7-15(17-12)18-21(19,20)14-10-8-13(9-11-14)16(2,3)4/h5-11H,1-4H3,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM29847 (N-(Pyridin-2-yl) arylsulfonamide, 7) Show SMILES Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(CC(=O)N2CCCC2)n1 Show InChI InChI=1S/C18H20ClN3O3S/c1-13-15(19)7-5-8-16(13)26(24,25)21-17-9-4-6-14(20-17)12-18(23)22-10-2-3-11-22/h4-9H,2-3,10-12H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Pfizer					Assay Description The enzyme assay was performed in a round-bottom 96-well plate. The enzyme was pre-incubated in the assay buffer in the presence of NADPH and inhibit...				Bioorg Med Chem Lett 19: 3493-7 (2009) Article DOI: 10.1016/j.bmcl.2009.05.011 BindingDB Entry DOI: 10.7270/Q2SB4428
					More data for this Ligand-Target Pair