Found 301 hits of ic50 data for polymerid = 1409 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50247012
(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O |r,t:18| Show InChI InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1 | KEGG
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| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi... |
Bioorg Med Chem Lett 19: 4455-8 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.033
BindingDB Entry DOI: 10.7270/Q2VT1T1D |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM13757
((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)Show SMILES CC(C)(Oc1ccccc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O |r,wU:17.17,19.19,14.14,wD:21.27,TLB:23:21:18:16.15.14,THB:16:17:20:23.15.14,22:17:14:23.20.21,24:21:18:16.15.14,(10.84,-3.12,;11.61,-4.45,;12.7,-3.37,;12.94,-5.22,;14.43,-4.83,;14.43,-3.29,;15.76,-2.52,;17.1,-3.29,;17.1,-4.83,;15.76,-5.6,;15.76,-7.14,;10.27,-5.22,;10.27,-6.76,;8.94,-4.45,;7.61,-5.22,;7.61,-6.76,;6.94,-7.93,;4.72,-7.16,;4.72,-5.12,;6.04,-4.32,;4.24,-5.07,;4.24,-6.31,;3.21,-7.32,;6.26,-7.03,;2.91,-5.54,;1.58,-6.31,;2.51,-4.05,)| Show InChI InChI=1S/C21H26ClNO4/c1-20(2,27-16-6-4-3-5-15(16)22)18(24)23-17-13-7-12-8-14(17)11-21(9-12,10-13)19(25)26/h3-6,12-14,17H,7-11H2,1-2H3,(H,23,24)(H,25,26)/t12-,13+,14?,17+,21+/m0/s1 | KEGG
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
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| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp... |
Bioorg Med Chem Lett 17: 750-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.074
BindingDB Entry DOI: 10.7270/Q2W66J13 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340383
(5-(4-(5,6,7,8,9,10-hexahydro-[1,2,4]triazolo[4,3-a...)Show InChI InChI=1S/C21H35N3O/c1-17(25)7-6-9-20-10-13-21(14-11-20,15-12-20)19-23-22-18-8-4-2-3-5-16-24(18)19/h17,25H,2-16H2,1H3 | KEGG
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| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2568-72 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.018
BindingDB Entry DOI: 10.7270/Q2QJ7HMK |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50247012
(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)Show SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O |r,t:18| Show InChI InChI=1S/C34H50O7/c1-29(2)23-10-13-34(7)27(32(23,5)12-11-24(29)41-26(38)9-8-25(36)37)22(35)18-20-21-19-31(4,28(39)40)15-14-30(21,3)16-17-33(20,34)6/h18,21,23-24,27H,8-17,19H2,1-7H3,(H,36,37)(H,39,40)/t21-,23-,24-,27+,30+,31-,32-,33+,34+/m0/s1 | KEGG
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| n/a | n/a | 206 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assay |
J Nat Prod 75: 599-604 (2012)
Article DOI: 10.1021/np200831c
BindingDB Entry DOI: 10.7270/Q27M090Q |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM13758
((1R,3R,4S,7S)-4-[2-(3-chlorophenoxy)-2-methylpropa...)Show SMILES CC(C)(Oc1cccc(Cl)c1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O |r,wU:17.17,19.19,14.14,wD:21.27,TLB:23:21:18:16.15.14,THB:16:17:20:23.15.14,22:17:14:23.20.21,24:21:18:16.15.14,(10.84,-3.12,;11.61,-4.45,;12.7,-3.37,;12.94,-5.22,;14.43,-4.83,;14.43,-3.29,;15.76,-2.52,;17.1,-3.29,;17.1,-4.83,;18.43,-5.6,;15.76,-5.6,;10.27,-5.22,;10.27,-6.76,;8.94,-4.45,;7.61,-5.22,;7.61,-6.76,;6.94,-7.93,;4.72,-7.16,;4.72,-5.12,;6.04,-4.32,;4.24,-5.07,;4.24,-6.31,;3.21,-7.32,;6.26,-7.03,;2.91,-5.54,;1.58,-6.31,;2.51,-4.05,)| Show InChI InChI=1S/C21H26ClNO4/c1-20(2,27-16-5-3-4-15(22)8-16)18(24)23-17-13-6-12-7-14(17)11-21(9-12,10-13)19(25)26/h3-5,8,12-14,17H,6-7,9-11H2,1-2H3,(H,23,24)(H,25,26)/t12-,13+,14?,17+,21+/m0/s1 | KEGG
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| PC cid
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| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp... |
Bioorg Med Chem Lett 17: 750-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.074
BindingDB Entry DOI: 10.7270/Q2W66J13 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50195290
(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)Show SMILES CC(C)(N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)N[C@H]1C2C[C@H]3CC1C[C@](C3)(C2)C(O)=O |wU:22.23,wD:25.27,29.36,TLB:21:22:30.25.26:28,THB:24:25:28:31.23.22,24:23:30.25.26:28,22:27:30:31.24.23,(21.86,-6.75,;20.53,-7.53,;19.71,-6.23,;21.34,-8.84,;20.6,-10.2,;21.41,-11.5,;22.95,-11.46,;23.68,-10.1,;22.87,-8.78,;23.76,-12.76,;23.02,-14.12,;23.82,-15.42,;25.37,-15.38,;26.1,-14.03,;25.29,-12.71,;26.17,-16.7,;26.93,-18.02,;27.49,-15.91,;24.83,-17.45,;19.24,-8.38,;19.34,-9.92,;17.86,-7.7,;16.58,-8.55,;16.57,-10.08,;15.56,-11.35,;14.15,-10.79,;14.15,-9.2,;15.18,-7.97,;13.84,-8.45,;13.85,-9.93,;12.65,-11.21,;15.17,-10.42,;12.3,-9.92,;11.53,-11.25,;11.54,-8.59,)| Show InChI InChI=1S/C25H33F3N4O3/c1-23(2,32-7-5-31(6-8-32)19-4-3-18(14-29-19)25(26,27)28)21(33)30-20-16-9-15-10-17(20)13-24(11-15,12-16)22(34)35/h3-4,14-17,20H,5-13H2,1-2H3,(H,30,33)(H,34,35)/t15-,16?,17?,20-,24- | KEGG
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PC cid
PC sid
UniChem
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| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA |
Bioorg Med Chem Lett 16: 5958-62 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.129
BindingDB Entry DOI: 10.7270/Q23R0SJT |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50195295
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...)Show SMILES OC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C1(CCCC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2 |wU:9.10,wD:3.2,TLB:6:5:36:8.7.9,6:7:4.5.35:36,THB:9:7:4:35.34.36,9:34:4:8.6.7,10:9:4.5.35:36,(-10.51,-26.96,;-9.74,-25.63,;-10.5,-24.3,;-8.2,-25.64,;-9.39,-26.91,;-7.89,-26.49,;-6.49,-27.06,;-5.48,-25.78,;-6.87,-26.13,;-5.47,-24.26,;-4.18,-23.41,;-2.81,-24.09,;-2.71,-25.63,;-1.53,-23.23,;-.44,-22.14,;-1.14,-20.76,;-2.67,-21.01,;-2.9,-22.54,;-.14,-23.92,;-.05,-25.45,;1.32,-26.14,;2.6,-25.29,;2.51,-23.75,;1.13,-23.06,;3.98,-25.98,;4.07,-27.51,;5.44,-28.2,;6.73,-27.35,;6.63,-25.81,;5.25,-25.13,;8.1,-28.04,;9.43,-28.8,;7.32,-29.36,;8.86,-26.7,;-6.86,-23.68,;-7.9,-24.9,;-8.21,-24.16,)| Show InChI InChI=1S/C27H35F3N4O3/c28-27(29,30)20-3-4-21(31-16-20)33-7-9-34(10-8-33)26(5-1-2-6-26)23(35)32-22-18-11-17-12-19(22)15-25(13-17,14-18)24(36)37/h3-4,16-19,22H,1-2,5-15H2,(H,32,35)(H,36,37)/t17?,18?,19?,22-,25- | KEGG
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| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA |
Bioorg Med Chem Lett 16: 5958-62 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.129
BindingDB Entry DOI: 10.7270/Q23R0SJT |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM13773
((1R,3R,4S,7S)-4-[2-(2-chlorophenoxy)-2-methylpropa...)Show SMILES CC(C)(Oc1ccccc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(=O)NS(C)(=O)=O |r,wU:17.17,19.19,14.14,wD:21.27,TLB:23:21:18:16.15.14,THB:16:17:20:23.15.14,22:17:14:23.20.21,24:21:18:16.15.14,(10.84,-3.12,;11.61,-4.45,;12.7,-3.37,;12.94,-5.22,;14.43,-4.83,;14.43,-3.29,;15.76,-2.52,;17.1,-3.29,;17.1,-4.83,;15.76,-5.6,;15.76,-7.14,;10.27,-5.22,;10.27,-6.76,;8.94,-4.45,;7.61,-5.22,;7.61,-6.76,;6.94,-7.93,;4.72,-7.16,;4.72,-5.12,;6.04,-4.32,;4.24,-5.07,;4.24,-6.31,;3.21,-7.32,;6.26,-7.03,;2.7,-6.31,;1.93,-4.98,;1.93,-7.64,;.39,-7.64,;-1.15,-7.64,;.39,-6.1,;.39,-9.18,)| Show InChI InChI=1S/C22H29ClN2O5S/c1-21(2,30-17-7-5-4-6-16(17)23)19(26)24-18-14-8-13-9-15(18)12-22(10-13,11-14)20(27)25-31(3,28)29/h4-7,13-15,18H,8-12H2,1-3H3,(H,24,26)(H,25,27)/t13-,14+,15?,18+,22+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp... |
Bioorg Med Chem Lett 17: 750-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.074
BindingDB Entry DOI: 10.7270/Q2W66J13 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM13772
(2-(2-chloro-4-fluorophenoxy)-2-methyl-N-[(1R,2S,5R...)Show SMILES CC(C)(Oc1ccc(F)cc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)c1nnn[nH]1 |r,wU:18.18,20.20,15.15,wD:22.28,TLB:24:22:19:17.16.15,THB:17:18:21:24.16.15,23:18:15:24.21.22,25:22:19:17.16.15,(10.84,-3.12,;11.61,-4.45,;12.7,-3.37,;12.94,-5.22,;14.43,-4.83,;14.43,-3.29,;15.76,-2.52,;17.1,-3.29,;18.43,-2.52,;17.1,-4.83,;15.76,-5.6,;15.76,-7.14,;10.27,-5.22,;10.27,-6.76,;8.94,-4.45,;7.61,-5.22,;7.61,-6.76,;6.94,-7.93,;4.72,-7.16,;4.72,-5.12,;6.04,-4.32,;4.24,-5.07,;4.24,-6.31,;3.21,-7.32,;6.26,-7.03,;2.76,-6.71,;1.9,-7.99,;.42,-7.57,;.36,-6.03,;1.8,-5.5,)| Show InChI InChI=1S/C21H25ClFN5O2/c1-20(2,30-16-4-3-14(23)7-15(16)22)19(29)24-17-12-5-11-6-13(17)10-21(8-11,9-12)18-25-27-28-26-18/h3-4,7,11-13,17H,5-6,8-10H2,1-2H3,(H,24,29)(H,25,26,27,28)/t11-,12+,13?,17+,21+/m0/s1 | KEGG
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp... |
Bioorg Med Chem Lett 17: 750-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.074
BindingDB Entry DOI: 10.7270/Q2W66J13 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM13755
((1R,3R,4S,7S)-4-(2-methyl-2-phenoxypropanamido)ada...)Show SMILES CC(C)(Oc1ccccc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O |r,wU:16.16,18.18,13.13,wD:20.26,TLB:22:20:17:15.14.13,THB:15:16:19:22.14.13,21:16:13:22.19.20,23:20:17:15.14.13,(10.84,-3.12,;11.61,-4.45,;12.7,-3.37,;12.94,-5.22,;14.43,-4.83,;14.43,-3.29,;15.76,-2.52,;17.1,-3.29,;17.1,-4.83,;15.76,-5.6,;10.27,-5.22,;10.27,-6.76,;8.94,-4.45,;7.61,-5.22,;7.61,-6.76,;6.94,-7.93,;4.72,-7.16,;4.72,-5.12,;6.04,-4.32,;4.24,-5.07,;4.24,-6.31,;3.21,-7.32,;6.26,-7.03,;2.91,-5.54,;1.58,-6.31,;2.51,-4.05,)| Show InChI InChI=1S/C21H27NO4/c1-20(2,26-16-6-4-3-5-7-16)18(23)22-17-14-8-13-9-15(17)12-21(10-13,11-14)19(24)25/h3-7,13-15,17H,8-12H2,1-2H3,(H,22,23)(H,24,25)/t13-,14+,15?,17+,21+/m0/s1 | KEGG
UniProtKB/SwissProt
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| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp... |
Bioorg Med Chem Lett 17: 750-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.074
BindingDB Entry DOI: 10.7270/Q2W66J13 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50193796
(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)Show SMILES CC1(C)C(COc2ccc(cn2)C(F)(F)F)CN([C@H]2C3CC4CC2C[C@](C4)(C3)c2nnn[nH]2)C1=O |wU:18.18,wD:25.31,TLB:18:19:26:22.23.24,17:18:26.21.22:24,THB:20:21:24:27.19.18,20:19:26.21.22:24,18:23:26:27.20.19,(18.43,-20.09,;17.11,-19.33,;17.56,-17.86,;16.63,-20.79,;17.54,-22.04,;19.08,-22,;19.87,-23.32,;19.13,-24.66,;19.92,-25.98,;21.47,-25.95,;22.21,-24.59,;21.41,-23.28,;22.22,-27.27,;22.98,-28.6,;20.89,-28.03,;23.55,-26.51,;15.09,-20.79,;14.62,-19.33,;13.15,-18.85,;11.84,-19.44,;10.31,-18.85,;10.25,-17.31,;11.7,-16.79,;13.16,-17.32,;12.16,-16.14,;10.72,-16.73,;9.31,-16.1,;10.85,-18.26,;10.72,-15.19,;11.96,-14.27,;11.48,-12.8,;9.93,-12.82,;9.46,-14.29,;15.86,-18.42,;15.86,-16.88,)| Show InChI InChI=1S/C24H29F3N6O2/c1-22(2)17(12-35-18-4-3-16(10-28-18)24(25,26)27)11-33(21(22)34)19-14-5-13-6-15(19)9-23(7-13,8-14)20-29-31-32-30-20/h3-4,10,13-15,17,19H,5-9,11-12H2,1-2H3,(H,29,30,31,32)/t13?,14?,15?,17?,19-,23- | KEGG
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| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 16: 5555-60 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.034
BindingDB Entry DOI: 10.7270/Q25X28K5 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50195300
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...)Show SMILES OC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C1(CCC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2 |wU:9.10,wD:3.2,TLB:6:5:35:8.7.9,6:7:4.5.34:35,THB:9:7:4:34.33.35,9:33:4:8.6.7,10:9:4.5.34:35,(11.08,-20.04,;11.85,-18.71,;11.09,-17.37,;13.39,-18.71,;12.2,-19.99,;13.7,-19.57,;15.1,-20.13,;16.11,-18.86,;14.72,-19.2,;16.13,-17.33,;17.41,-16.48,;18.79,-17.17,;18.88,-18.7,;20.07,-16.31,;21.16,-15.21,;20.06,-14.13,;18.97,-15.22,;21.45,-17,;21.54,-18.53,;22.91,-19.21,;24.19,-18.36,;24.1,-16.83,;22.72,-16.14,;25.57,-19.05,;25.66,-20.59,;27.03,-21.28,;28.32,-20.43,;28.22,-18.88,;26.84,-18.2,;29.69,-21.12,;31.02,-21.88,;28.91,-22.44,;30.45,-19.77,;14.73,-16.75,;13.69,-17.98,;13.38,-17.23,)| Show InChI InChI=1S/C26H33F3N4O3/c27-26(28,29)19-2-3-20(30-15-19)32-6-8-33(9-7-32)25(4-1-5-25)22(34)31-21-17-10-16-11-18(21)14-24(12-16,13-17)23(35)36/h2-3,15-18,21H,1,4-14H2,(H,31,34)(H,35,36)/t16?,17?,18?,21-,24- | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA |
Bioorg Med Chem Lett 16: 5958-62 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.129
BindingDB Entry DOI: 10.7270/Q23R0SJT |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM13759
((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)Show SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(O)=O |r,wU:17.17,19.19,14.14,wD:21.27,TLB:23:21:18:16.15.14,THB:16:17:20:23.15.14,22:17:14:23.20.21,24:21:18:16.15.14,(10.84,-3.12,;11.61,-4.45,;12.7,-3.37,;12.94,-5.22,;14.43,-4.83,;14.43,-3.29,;15.76,-2.52,;17.1,-3.29,;18.43,-2.52,;17.1,-4.83,;15.76,-5.6,;10.27,-5.22,;10.27,-6.76,;8.94,-4.45,;7.61,-5.22,;7.61,-6.76,;6.94,-7.93,;4.72,-7.16,;4.72,-5.12,;6.04,-4.32,;4.24,-5.07,;4.24,-6.31,;3.21,-7.32,;6.26,-7.03,;2.91,-5.54,;1.58,-6.31,;2.51,-4.05,)| Show InChI InChI=1S/C21H26ClNO4/c1-20(2,27-16-5-3-15(22)4-6-16)18(24)23-17-13-7-12-8-14(17)11-21(9-12,10-13)19(25)26/h3-6,12-14,17H,7-11H2,1-2H3,(H,23,24)(H,25,26)/t12-,13+,14?,17+,21+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
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| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description
The in Vitro 11beta-HSD2 dehydrogenase assays were developed using the cell lysates that had the full length human or mouse 11beta-HSD2 cDNA over exp... |
Bioorg Med Chem Lett 17: 750-5 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.074
BindingDB Entry DOI: 10.7270/Q2W66J13 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50192685
((3s,9s)-9-(2-(4-chlorophenoxy)-2-methylpropanamido...)Show SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@@H]1C2CCCC1C[C@H](C2)C(O)=O |wD:14.14,21.25,TLB:13:14:22.21.20:16.18.17,THB:23:21:16.18.17:14,(.09,-10.48,;1.44,-9.72,;2.77,-10.5,;2.77,-8.95,;2.77,-7.42,;4.1,-6.65,;4.11,-5.11,;2.77,-4.34,;2.77,-2.8,;1.44,-5.12,;1.44,-6.65,;.11,-8.95,;.11,-7.41,;-.79,-9.46,;-2.25,-8.62,;-2.83,-10.19,;-2.83,-12.52,;-4.87,-12.46,;-3.87,-11.76,;-3.87,-9.08,;-5.21,-9.09,;-5.73,-8.15,;-5.76,-10.11,;-7.23,-8.55,;-8.31,-7.46,;-7.63,-10.03,)| Show InChI InChI=1S/C20H26ClNO4/c1-20(2,26-16-8-6-15(21)7-9-16)19(25)22-17-12-4-3-5-13(17)11-14(10-12)18(23)24/h6-9,12-14,17H,3-5,10-11H2,1-2H3,(H,22,25)(H,23,24)/t12?,13?,14-,17+ | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 16: 5408-13 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.062
BindingDB Entry DOI: 10.7270/Q2XG9QRS |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50174285
(3-(4-pentylbicyclo[2.2.2]octan-1-yl)-5,6,7,8,9,10-...)Show InChI InChI=1S/C21H35N3/c1-2-3-7-10-20-11-14-21(15-12-20,16-13-20)19-23-22-18-9-6-4-5-8-17-24(18)19/h2-17H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck & Co.
Curated by ChEMBL
| Assay Description
Inhibitory activity against mouse 11beta-HSD2 |
Bioorg Med Chem Lett 15: 5266-9 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.052
BindingDB Entry DOI: 10.7270/Q2QC031M |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50174285
(3-(4-pentylbicyclo[2.2.2]octan-1-yl)-5,6,7,8,9,10-...)Show InChI InChI=1S/C21H35N3/c1-2-3-7-10-20-11-14-21(15-12-20,16-13-20)19-23-22-18-9-6-4-5-8-17-24(18)19/h2-17H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assay |
Bioorg Med Chem Lett 21: 2568-72 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.018
BindingDB Entry DOI: 10.7270/Q2QJ7HMK |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50195288
(4-{2-cyclopropyl-2-[4-(5-trifluoromethyl-pyridin-2...)Show SMILES OC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)C(C1CC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2 |wU:9.10,wD:3.2,TLB:6:5:35:8.7.9,6:7:4.5.34:35,THB:9:7:4:34.33.35,9:33:4:8.6.7,10:9:4.5.34:35,(-9.11,-13.49,;-8.34,-12.16,;-9.1,-10.83,;-6.8,-12.17,;-7.99,-13.45,;-6.49,-13.03,;-5.09,-13.59,;-4.07,-12.32,;-5.47,-12.66,;-4.06,-10.79,;-2.78,-9.94,;-1.4,-10.62,;-1.3,-12.16,;-.12,-9.77,;-.21,-8.23,;.46,-6.85,;-1.07,-6.95,;1.26,-10.45,;1.35,-11.98,;2.73,-12.67,;4.01,-11.82,;3.92,-10.28,;2.54,-9.59,;5.39,-12.51,;5.48,-14.05,;6.85,-14.74,;8.14,-13.89,;8.04,-12.34,;6.67,-11.66,;9.52,-14.57,;10.84,-15.34,;8.73,-15.9,;10.27,-13.23,;-5.46,-10.21,;-6.5,-11.44,;-6.8,-10.69,)| Show InChI InChI=1S/C26H33F3N4O3/c27-26(28,29)19-3-4-20(30-14-19)32-5-7-33(8-6-32)22(16-1-2-16)23(34)31-21-17-9-15-10-18(21)13-25(11-15,12-17)24(35)36/h3-4,14-18,21-22H,1-2,5-13H2,(H,31,34)(H,35,36)/t15?,17?,18?,21-,22?,25- | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA |
Bioorg Med Chem Lett 16: 5958-62 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.129
BindingDB Entry DOI: 10.7270/Q23R0SJT |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50195294
(4-({1-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazi...)Show SMILES OC(=O)[C@@]12C[C@H]3CC(C1)[C@H](NC(=O)C1(CC1)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2 |wU:9.10,wD:3.2,5.4,TLB:6:5:34:8.7.9,6:7:4.5.33:34,THB:10:9:4.5.33:34,(-7.99,-22.89,;-7.21,-21.56,;-7.98,-20.22,;-5.67,-21.56,;-6.87,-22.84,;-5.37,-22.42,;-3.96,-22.98,;-2.95,-21.71,;-4.35,-22.05,;-2.94,-20.18,;-1.66,-19.33,;-.28,-20.02,;-.18,-21.55,;1,-19.16,;.6,-17.67,;2.09,-18.07,;1.82,-20.47,;1.08,-21.83,;1.89,-23.13,;3.43,-23.09,;4.16,-21.73,;3.34,-20.42,;4.23,-24.39,;3.5,-25.75,;4.3,-27.05,;5.84,-27.01,;6.57,-25.66,;5.77,-24.34,;6.64,-28.33,;7.4,-29.65,;7.97,-27.54,;5.3,-29.08,;-4.34,-19.6,;-5.37,-20.83,;-5.68,-20.08,)| Show InChI InChI=1S/C25H31F3N4O3/c26-25(27,28)18-1-2-19(29-14-18)31-5-7-32(8-6-31)24(3-4-24)21(33)30-20-16-9-15-10-17(20)13-23(11-15,12-16)22(34)35/h1-2,14-17,20H,3-13H2,(H,30,33)(H,34,35)/t15-,16?,17?,20-,23- | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA |
Bioorg Med Chem Lett 16: 5958-62 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.129
BindingDB Entry DOI: 10.7270/Q23R0SJT |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50195291
(4-{2-methyl-2-[4-(5-trifluoromethyl-pyridin-2-yl)-...)Show SMILES CC(C)(N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)N[C@H]1C2C[C@H]3CC1C[C@](C3)(C2)C(N)=O |wU:22.23,wD:25.27,29.36,TLB:21:22:30.25.26:28,THB:24:25:28:31.23.22,24:23:30.25.26:28,22:27:30:31.24.23,(-.43,-31.93,;.38,-33.24,;1.71,-32.46,;1.2,-34.54,;.46,-35.9,;1.27,-37.21,;2.81,-37.16,;3.54,-35.81,;2.72,-34.49,;3.61,-38.47,;2.88,-39.82,;3.68,-41.13,;5.22,-41.09,;5.95,-39.73,;5.15,-38.42,;6.02,-42.4,;6.78,-43.73,;7.35,-41.62,;4.68,-43.16,;-.9,-34.09,;-.81,-35.62,;-2.28,-33.4,;-3.56,-34.25,;-3.58,-35.78,;-4.59,-37.06,;-5.99,-36.49,;-6,-34.9,;-4.96,-33.67,;-6.31,-34.15,;-6.3,-35.64,;-7.5,-36.91,;-4.97,-36.13,;-7.84,-35.63,;-8.62,-36.96,;-8.6,-34.29,)| Show InChI InChI=1S/C25H34F3N5O2/c1-23(2,33-7-5-32(6-8-33)19-4-3-18(14-30-19)25(26,27)28)22(35)31-20-16-9-15-10-17(20)13-24(11-15,12-16)21(29)34/h3-4,14-17,20H,5-13H2,1-2H3,(H2,29,34)(H,31,35)/t15-,16?,17?,20-,24- | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 assessed as cortisol disappearance by SPA |
Bioorg Med Chem Lett 16: 5958-62 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.129
BindingDB Entry DOI: 10.7270/Q23R0SJT |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340796
(CHEMBL1760687 | N-(4-(5-(1-(4-chlorophenyl)cyclobu...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(NC(=O)c2ccno2)cc1 Show InChI InChI=1S/C23H20ClN5O2/c1-29-20(15-3-9-18(10-4-15)26-21(30)19-11-14-25-31-19)27-28-22(29)23(12-2-13-23)16-5-7-17(24)8-6-16/h3-11,14H,2,12-13H2,1H3,(H,26,30) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340807
(CHEMBL1760689 | N-(3-chloro-4-(5-(1-(4-chloropheny...)Show SMILES CC(=O)Nc1ccc(-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(Cl)c1 Show InChI InChI=1S/C21H20Cl2N4O/c1-13(28)24-16-8-9-17(18(23)12-16)19-25-26-20(27(19)2)21(10-3-11-21)14-4-6-15(22)7-5-14/h4-9,12H,3,10-11H2,1-2H3,(H,24,28) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340808
(CHEMBL1760690 | N-(3-chloro-4-(5-(1-(4-chloropheny...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(NC(=O)c2cnccn2)cc1Cl Show InChI InChI=1S/C24H20Cl2N6O/c1-32-21(30-31-23(32)24(9-2-10-24)15-3-5-16(25)6-4-15)18-8-7-17(13-19(18)26)29-22(33)20-14-27-11-12-28-20/h3-8,11-14H,2,9-10H2,1H3,(H,29,33) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340812
(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1cncnc1 Show InChI InChI=1S/C23H20ClN5/c1-29-21(17-5-3-16(4-6-17)18-13-25-15-26-14-18)27-28-22(29)23(11-2-12-23)19-7-9-20(24)10-8-19/h3-10,13-15H,2,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340813
(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1cnc(N)nc1 Show InChI InChI=1S/C23H21ClN6/c1-30-20(16-5-3-15(4-6-16)17-13-26-22(25)27-14-17)28-29-21(30)23(11-2-12-23)18-7-9-19(24)10-8-18/h3-10,13-14H,2,11-12H2,1H3,(H2,25,26,27) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340814
(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1cnc(=O)[nH]c1 Show InChI InChI=1S/C23H20ClN5O/c1-29-20(16-5-3-15(4-6-16)17-13-25-22(30)26-14-17)27-28-21(29)23(11-2-12-23)18-7-9-19(24)10-8-18/h3-10,13-14H,2,11-12H2,1H3,(H,25,26,30) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340815
(5-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES COc1ncc(-c2ccc(cc2)-c2nnc(n2C)C2(CCC2)c2ccc(Cl)cc2)c(OC)n1 Show InChI InChI=1S/C25H24ClN5O2/c1-31-21(29-30-23(31)25(13-4-14-25)18-9-11-19(26)12-10-18)17-7-5-16(6-8-17)20-15-27-24(33-3)28-22(20)32-2/h5-12,15H,4,13-14H2,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340816
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1cnccn1 Show InChI InChI=1S/C23H20ClN5/c1-29-21(17-5-3-16(4-6-17)20-15-25-13-14-26-20)27-28-22(29)23(11-2-12-23)18-7-9-19(24)10-8-18/h3-10,13-15H,2,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340817
(6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1cc(=O)[nH]cn1 Show InChI InChI=1S/C23H20ClN5O/c1-29-21(16-5-3-15(4-6-16)19-13-20(30)26-14-25-19)27-28-22(29)23(11-2-12-23)17-7-9-18(24)10-8-17/h3-10,13-14H,2,11-12H2,1H3,(H,25,26,30) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340818
(3-chloro-6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1ccc(Cl)nn1 Show InChI InChI=1S/C23H19Cl2N5/c1-30-21(16-5-3-15(4-6-16)19-11-12-20(25)27-26-19)28-29-22(30)23(13-2-14-23)17-7-9-18(24)10-8-17/h3-12H,2,13-14H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340819
(6-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1ccc(N)nn1 Show InChI InChI=1S/C23H21ClN6/c1-30-21(16-5-3-15(4-6-16)19-11-12-20(25)27-26-19)28-29-22(30)23(13-2-14-23)17-7-9-18(24)10-8-17/h3-12H,2,13-14H2,1H3,(H2,25,27) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340820
(4-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1cnoc1 Show InChI InChI=1S/C22H19ClN4O/c1-27-20(16-5-3-15(4-6-16)17-13-24-28-14-17)25-26-21(27)22(11-2-12-22)18-7-9-19(23)10-8-18/h3-10,13-14H,2,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340821
(4-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cc1noc(C)c1-c1ccc(cc1)-c1nnc(n1C)C1(CCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H23ClN4O/c1-15-21(16(2)30-28-15)17-5-7-18(8-6-17)22-26-27-23(29(22)3)24(13-4-14-24)19-9-11-20(25)12-10-19/h5-12H,4,13-14H2,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340797
(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1)-c1ccon1 Show InChI InChI=1S/C22H19ClN4O/c1-27-20(16-5-3-15(4-6-16)19-11-14-28-26-19)24-25-21(27)22(12-2-13-22)17-7-9-18(23)10-8-17/h3-11,14H,2,12-13H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50260908
(3-(3-chloro-4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1cccnc1 Show InChI InChI=1S/C24H20Cl2N4/c1-30-22(20-10-5-16(14-21(20)26)17-4-2-13-27-15-17)28-29-23(30)24(11-3-12-24)18-6-8-19(25)9-7-18/h2,4-10,13-15H,3,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340799
(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1F)-c1cccnc1 Show InChI InChI=1S/C24H20ClFN4/c1-30-22(20-10-5-16(14-21(20)26)17-4-2-13-27-15-17)28-29-23(30)24(11-3-12-24)18-6-8-19(25)9-7-18/h2,4-10,13-15H,3,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340800
(3-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES COc1cc(ccc1-c1nnc(n1C)C1(CCC1)c1ccc(Cl)cc1)-c1cccnc1 Show InChI InChI=1S/C25H23ClN4O/c1-30-23(21-11-6-17(15-22(21)31-2)18-5-3-14-27-16-18)28-29-24(30)25(12-4-13-25)19-7-9-20(26)10-8-19/h3,5-11,14-16H,4,12-13H2,1-2H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340801
(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1O)-c1cccnc1 Show InChI InChI=1S/C24H21ClN4O/c1-29-22(20-10-5-16(14-21(20)30)17-4-2-13-26-15-17)27-28-23(29)24(11-3-12-24)18-6-8-19(25)9-7-18/h2,4-10,13-15,30H,3,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340802
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1F)-c1cnccn1 Show InChI InChI=1S/C23H19ClFN5/c1-30-21(18-8-3-15(13-19(18)25)20-14-26-11-12-27-20)28-29-22(30)23(9-2-10-23)16-4-6-17(24)7-5-16/h3-8,11-14H,2,9-10H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340803
(2-(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1OC(F)F)-c1cnccn1 Show InChI InChI=1S/C24H20ClF2N5O/c1-32-21(30-31-22(32)24(9-2-10-24)16-4-6-17(25)7-5-16)18-8-3-15(13-20(18)33-23(26)27)19-14-28-11-12-29-19/h3-8,11-14,23H,2,9-10H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340804
(2-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1C(N)=O)-c1cnccn1 Show InChI InChI=1S/C24H21ClN6O/c1-31-22(18-8-3-15(13-19(18)21(26)32)20-14-27-11-12-28-20)29-30-23(31)24(9-2-10-24)16-4-6-17(25)7-5-16/h3-8,11-14H,2,9-10H2,1H3,(H2,26,32) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340805
(4-(5-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-4H-1,...)Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1C(N)=O)C(N)=O Show InChI InChI=1S/C21H20ClN5O2/c1-27-19(15-8-3-12(17(23)28)11-16(15)18(24)29)25-26-20(27)21(9-2-10-21)13-4-6-14(22)7-5-13/h3-8,11H,2,9-10H2,1H3,(H2,23,28)(H2,24,29) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50340831
(2-(3-chloro-4-(5-(1-(4-chlorophenyl)-3-fluorocyclo...)Show SMILES Cn1c(nnc1C1(CC(F)C1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1cnccn1 Show InChI InChI=1S/C23H18Cl2FN5/c1-31-21(18-7-2-14(10-19(18)25)20-13-27-8-9-28-20)29-30-22(31)23(11-17(26)12-23)15-3-5-16(24)6-4-15/h2-10,13,17H,11-12H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11beta-HSD2 |
Bioorg Med Chem Lett 21: 2141-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.01.125
BindingDB Entry DOI: 10.7270/Q2W37WNN |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377877
(CHEMBL256571)Show InChI InChI=1S/C20H27N3/c1-2-10-16-23-18(13-7-1)21-22-19(23)20(14-8-4-9-15-20)17-11-5-3-6-12-17/h3,5-6,11-12H,1-2,4,7-10,13-16H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377884
(CHEMBL403993)Show InChI InChI=1S/C17H19Cl2N3/c18-12-6-7-13(14(19)11-12)17(8-9-17)16-21-20-15-5-3-1-2-4-10-22(15)16/h6-7,11H,1-5,8-10H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377885
(CHEMBL402995)Show InChI InChI=1S/C17H21N3/c1-2-7-13-20-15(10-6-1)18-19-16(20)17(11-12-17)14-8-4-3-5-9-14/h3-5,8-9H,1-2,6-7,10-13H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377866
(CHEMBL257148)Show InChI InChI=1S/C19H25N3/c1-15-8-6-9-16(14-15)19(11-7-12-19)18-21-20-17-10-4-2-3-5-13-22(17)18/h6,8-9,14H,2-5,7,10-13H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377867
(CHEMBL256514)Show InChI InChI=1S/C18H22FN3/c19-15-9-7-14(8-10-15)18(11-5-12-18)17-21-20-16-6-3-1-2-4-13-22(16)17/h7-10H,1-6,11-13H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377870
(CHEMBL256515)Show InChI InChI=1S/C20H27N3/c1-16-9-11-17(12-10-16)20(13-5-6-14-20)19-22-21-18-8-4-2-3-7-15-23(18)19/h9-12H,2-8,13-15H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377873
(CHEMBL402613)Show InChI InChI=1S/C19H24FN3/c20-16-10-8-15(9-11-16)19(12-4-5-13-19)18-22-21-17-7-3-1-2-6-14-23(17)18/h8-11H,1-7,12-14H2 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
11-beta-hydroxysteroid dehydrogenase type 2
(Mus musculus (mouse)) | BDBM50377875
(CHEMBL256090)Show InChI InChI=1S/C21H29N3/c1-17-10-12-18(13-11-17)21(14-6-4-7-15-21)20-23-22-19-9-5-2-3-8-16-24(19)20/h10-13H,2-9,14-16H2,1H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of mouse 11-beta-HSD2 by SPA assay |
Bioorg Med Chem Lett 18: 3412-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.014
BindingDB Entry DOI: 10.7270/Q2H99625 |
More data for this
Ligand-Target Pair | |
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