new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 306 hits of ic50 for UniProtKB: P22909   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50029050
PNG
((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Show SMILES CNC[C@H](O)c1ccc(O)c(O)c1 |r|
Show InChI InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 0n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 24: 1258-60 (1981)


BindingDB Entry DOI: 10.7270/Q27W6FDS
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50029051
PNG
((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Show SMILES NC[C@H](O)c1ccc(O)c(O)c1 |r|
Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 0n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 24: 1258-60 (1981)


BindingDB Entry DOI: 10.7270/Q27W6FDS
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50223423
PNG
(CHEMBL22352)
Show SMILES NCC(c1ccc(O)c(O)c1)S(O)(=O)=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 0.00000400n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 24: 1258-60 (1981)


BindingDB Entry DOI: 10.7270/Q27W6FDS
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50223422
PNG
(CHEMBL22195)
Show SMILES CNCC(c1ccc(O)c(O)c1)S(O)(=O)=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 0.0000100n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 24: 1258-60 (1981)


BindingDB Entry DOI: 10.7270/Q27W6FDS
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (Rat)-RAT-NEONATAL RAT-Rattus no...)
BDBM50223424
PNG
(CHEMBL280151)
Show SMILES CC(C)NCC(c1ccc(O)c(O)c1)S(O)(=O)=O
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 0.0000330n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 24: 1258-60 (1981)


BindingDB Entry DOI: 10.7270/Q27W6FDS
More data for this
Ligand-Target Pair
Adrenergic receptor alpha


(Rattus norvegicus (rat))
BDBM50034043
PNG
(1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperi...)
Show SMILES COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O
Show InChI InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 0.400n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against Alpha-1 adrenergic receptor was determined using [3H]WB-4101 radioligand


J Med Chem 38: 1119-31 (1995)


BindingDB Entry DOI: 10.7270/Q2S75H08
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225293
PNG
(CHEBI:5553 | GUANABENZ | Guanabenz | WY-8678)
Show SMILES NC(=N)N\N=C\c1c(Cl)cccc1Cl
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 1.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50019646
PNG
(2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline ...)
Show SMILES CC(Oc1c(Cl)cccc1Cl)C1=NCCN1 |t:12|
Show InChI InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 2.5n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225285
PNG
(CHEBI:3757 | CLONIDINE | Catapres | Catapres-Tts-1...)
Show SMILES Clc1cccc(Cl)c1NC1=NCCN1 |t:10|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 3.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50226942
PNG
(CHEMBL39286)
Show SMILES [H][C@@]1(C)c2ccccc2N(C)[C@]1([H])C1=NCCN1 |t:15|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 3.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 30: 1555-62 (1987)


BindingDB Entry DOI: 10.7270/Q2NC63FN
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50226153
PNG
(CHEMBL545092)
Show SMILES Br.Oc1ccc2C(CCc2c1O)C1=NCCN1 |t:13|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 3.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 463-7 (1986)


BindingDB Entry DOI: 10.7270/Q26D5W7D
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50019646
PNG
(2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline ...)
Show SMILES CC(Oc1c(Cl)cccc1Cl)C1=NCCN1 |t:12|
Show InChI InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 3.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 1183-8 (1986)


BindingDB Entry DOI: 10.7270/Q25H7JFF
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM34572
PNG
(BRIMONIDINE | CHEMBL844 | MLS000069370 | SMR000058...)
Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 |t:4|
Show InChI InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 3.60n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50295557
PNG
(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-...)
Show SMILES CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)N[C@]1(C)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](Cc3ccccc3)N2C1=O |r|
Show InChI InChI=1S/C33H37N5O5/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39)/t21-,23-,25-,26+,27+,32-,33+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 3.70n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of specific [3H]prazosin binding (0.2 nM) to rat brain membranes alpha-1 adrenergic receptor


J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225285
PNG
(CHEBI:3757 | CLONIDINE | Catapres | Catapres-Tts-1...)
Show SMILES Clc1cccc(Cl)c1NC1=NCCN1 |t:10|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 3.90n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 30: 1555-62 (1987)


BindingDB Entry DOI: 10.7270/Q2NC63FN
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50001922
PNG
(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
Show SMILES C(C1=NCCN1)c1cccc2ccccc12 |t:1|
Show InChI InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 4.80n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM30712
PNG
(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Show SMILES Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C |t:11|
Show InChI InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 5n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225247
PNG
(CHEMBL44558)
Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1OCCN2c1ccccc1)c34
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 7n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50226155
PNG
(CHEMBL543684)
Show SMILES Br.Oc1ccc2C(CCCc2c1O)C1=NCCN1 |t:14|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 7n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 463-7 (1986)


BindingDB Entry DOI: 10.7270/Q26D5W7D
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50070193
PNG
(1-((6aR,9R,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,...)
Show SMILES CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cc(cc2c34)C(C)(C)C)N(C)C1
Show InChI InChI=1S/C28H43N5O2/c1-8-29-27(35)33(11-9-10-31(5)6)26(34)19-12-21-22-14-20(28(2,3)4)15-23-25(22)18(16-30-23)13-24(21)32(7)17-19/h14-16,19,21,24,30H,8-13,17H2,1-7H3,(H,29,35)/t19-,21-,24-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 7n/an/an/an/an/an/a



Pharmacia & Upjohn S.p.A.-CNS Research

Curated by ChEMBL




Bioorg Med Chem Lett 8: 1117-22 (1999)


BindingDB Entry DOI: 10.7270/Q2M61JF3
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50019646
PNG
(2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline ...)
Show SMILES CC(Oc1c(Cl)cccc1Cl)C1=NCCN1 |t:12|
Show InChI InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 7.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 1183-8 (1986)


BindingDB Entry DOI: 10.7270/Q25H7JFF
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50048608
PNG
(CHEMBL154488 | Indol-1-yl-pyridin-4-yl-amine)
Show SMILES N(c1ccncc1)n1ccc2ccccc12
Show InChI InChI=1S/C13H11N3/c1-2-4-13-11(3-1)7-10-16(13)15-12-5-8-14-9-6-12/h1-10H,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 8n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex


J Med Chem 39: 570-81 (1996)


Article DOI: 10.1021/jm9506433
BindingDB Entry DOI: 10.7270/Q2BR8R7K
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM29568
PNG
(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1
Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 8n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Angiotensin I converting enzyme


J Med Chem 28: 1142-5 (1985)


BindingDB Entry DOI: 10.7270/Q21V5H5W
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225292
PNG
(HOE-440 | Symcor Base TTS | TIAMENIDINE | Tiamenid...)
Show SMILES Cc1csc(Cl)c1NC1=NCCN1 |t:9|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 9.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50013515
PNG
((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Show SMILES COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r|
Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 9.10n/an/an/an/an/an/a



Institut de Pharmacologie (UA 589 CNRS)

Curated by ChEMBL




J Med Chem 32: 1402-7 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ92M9
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM31046
PNG
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10|
Show InChI InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
PC cid
PC sid
UniChem
PubMed
n/an/a 10n/an/an/an/an/an/a



Institut de Pharmacologie (UA 589 CNRS)

Curated by ChEMBL




J Med Chem 32: 1402-7 (1989)


BindingDB Entry DOI: 10.7270/Q2SQ92M9
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225294
PNG
(CHEMBL146100)
Show SMILES Oc1ccc(NC2=NCCN2)cc1O |t:6|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 14n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225288
PNG
(TRAMAZOLINE | Tramazoline)
Show SMILES C1CN=C(Nc2cccc3CCCCc23)N1 |t:2|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 16n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225290
PNG
(CHEMBL146419)
Show SMILES CN(C)C1CCc2c(C1)ccc(O)c2O
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 17n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225285
PNG
(CHEBI:3757 | CLONIDINE | Catapres | Catapres-Tts-1...)
Show SMILES Clc1cccc(Cl)c1NC1=NCCN1 |t:10|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PubMed
n/an/a 17n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 1183-8 (1986)


BindingDB Entry DOI: 10.7270/Q25H7JFF
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225235
PNG
(CHEMBL42909)
Show SMILES [H][C@@]12CCc3ccccc3C1OCCN2CC
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 19n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM31046
PNG
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10|
Show InChI InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
PC cid
PC sid
UniChem
PubMed
n/an/a 20n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM30703
PNG
(2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline...)
Show SMILES Cc1cc(cc(C)c1CC1=NCCN1)C(C)(C)C |t:10|
Show InChI InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 23n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50048589
PNG
(CHEMBL152842 | Indol-1-yl-methyl-pyridin-4-yl-amin...)
Show SMILES CN(c1ccncc1)n1ccc2ccccc12
Show InChI InChI=1S/C14H13N3/c1-16(13-6-9-15-10-7-13)17-11-8-12-4-2-3-5-14(12)17/h2-11H,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 24n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex


J Med Chem 39: 570-81 (1996)


Article DOI: 10.1021/jm9506433
BindingDB Entry DOI: 10.7270/Q2BR8R7K
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM86053
PNG
(B-HT 920 | CAS_101626-70-4 | CHEMBL279085 | NSC_10...)
Show SMILES Nc1nc2CCN(CC=C)CCc2s1
Show InChI InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 25n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225241
PNG
(CHEMBL42242)
Show SMILES [H][C@@]12CCc3ccc(O)cc3C1OCCN2CC
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 29n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM96559
PNG
(2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-...)
Show SMILES C1CN=C(N1)C1CCCc2ccccc12 |c:2|
Show InChI InChI=1S/C13H16N2/c1-2-6-11-10(4-1)5-3-7-12(11)13-14-8-9-15-13/h1-2,4,6,12H,3,5,7-9H2,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 30n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50029051
PNG
((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Show SMILES NC[C@H](O)c1ccc(O)c(O)c1 |r|
Show InChI InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

PubMed
n/an/a 33n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 463-7 (1986)


BindingDB Entry DOI: 10.7270/Q26D5W7D
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM31046
PNG
(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Show SMILES Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10|
Show InChI InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
PC cid
PC sid
UniChem
PubMed
n/an/a 38n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 1183-8 (1986)


BindingDB Entry DOI: 10.7270/Q25H7JFF
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225248
PNG
(CHEMBL42309)
Show SMILES [H][C@@]12CCc3ccc(O)cc3C1OCCN2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 39n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50001884
PNG
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)
Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8|
Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 40n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 1628-37 (1986)


BindingDB Entry DOI: 10.7270/Q2319TVF
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50017543
PNG
((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)
Show SMILES CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 |r|
Show InChI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 41n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50019646
PNG
(2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline ...)
Show SMILES CC(Oc1c(Cl)cccc1Cl)C1=NCCN1 |t:12|
Show InChI InChI=1S/C11H12Cl2N2O/c1-7(11-14-5-6-15-11)16-10-8(12)3-2-4-9(10)13/h2-4,7H,5-6H2,1H3,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 43n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 1183-8 (1986)


BindingDB Entry DOI: 10.7270/Q25H7JFF
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50226156
PNG
(CHEMBL544627)
Show SMILES Br.Oc1ccc2C(Cc2c1O)C1=NCCN1 |t:12|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 49n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 29: 463-7 (1986)


BindingDB Entry DOI: 10.7270/Q26D5W7D
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225250
PNG
(CHEMBL42237)
Show SMILES [H][C@@]12CCc3ccccc3C1OCCN2CCC
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 51n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225251
PNG
(CHEMBL295359)
Show SMILES [H][C@@]12CCc3c(O)cccc3C1OCCN2CC
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 53n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50027060
PNG
(2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imi...)
Show SMILES C(Oc1ccccc1C1CC1)C1=NCCN1 |t:13|
Show InChI InChI=1S/C13H16N2O/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13/h1-4,10H,5-9H2,(H,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 59n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 495-503 (1984)


BindingDB Entry DOI: 10.7270/Q24B31WH
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50001955
PNG
((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r|
Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 63n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50225234
PNG
(CHEMBL41980)
Show SMILES [H][C@@]12CCc3ccc(O)cc3C1OCCN2C
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 71n/an/an/an/an/an/a



TBA

Curated by ChEMBL




J Med Chem 27: 1607-13 (1984)


BindingDB Entry DOI: 10.7270/Q2SJ1NT8
More data for this
Ligand-Target Pair
Adrenergic receptor alpha-2


(RAT-NEONATAL RAT-Rattus norvegicus (rat))
BDBM50067212
PNG
(CHEBI:8093 | Cyclomydril | Duo-Medihaler | PHENYLE...)
Show SMILES CNC[C@H](O)c1cccc(O)c1 |r|
Show InChI InChI=1/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/s2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

DrugBank
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 78n/an/an/an/an/an/a



Reckitt& Colman plc

Curated by ChEMBL




J Med Chem 32: 1627-30 (1989)


BindingDB Entry DOI: 10.7270/Q28S4S4V
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 306 total )  |  Next  |  Last  >>
Jump to: