Compile Data Set for Download or QSAR

Found 2558 hits of ic50 for UniProtKB: P23977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50051753 (1-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-yl)...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3ccccc3c1)N2 |THB:11:10:21:6.7,2:4:21:6.7| Show InChI InChI=1S/C20H23NO/c1-2-19(22)20-17(12-16-9-10-18(20)21-16)15-8-7-13-5-3-4-6-14(13)11-15/h3-8,11,16-18,20-21H,2,9-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041293 (1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3ccccc3c1)N2C |THB:22:21:4.10.9:6.7,11:10:21:6.7,2:4:21:6.7| Show InChI InChI=1S/C21H25NO/c1-3-20(23)21-18(13-17-10-11-19(21)22(17)2)16-9-8-14-6-4-5-7-15(14)12-16/h4-9,12,17-19,21H,3,10-11,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0430	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.				J Med Chem 37: 1262-8 (1994) BindingDB Entry DOI: 10.7270/Q2TH8NBM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50111889 (1-[3-(3-Chloro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc(I)c(Cl)c1)N2C |TLB:20:19:4.10.9:6.7,THB:2:4:19:6.7| Show InChI InChI=1S/C17H21ClINO/c1-3-16(21)17-12(9-11-5-7-15(17)20(11)2)10-4-6-14(19)13(18)8-10/h4,6,8,11-12,15,17H,3,5,7,9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0770	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporter				Bioorg Med Chem Lett 12: 845-7 (2002) BindingDB Entry DOI: 10.7270/Q25M6515
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50111893 (1-[3-(3-Chloro-4-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc(I)c(Cl)c1)N2 |THB:2:4:19:6.7| Show InChI InChI=1S/C16H19ClINO/c1-2-15(20)16-11(8-10-4-6-14(16)19-10)9-3-5-13(18)12(17)7-9/h3,5,7,10-11,14,16,19H,2,4,6,8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.0850	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporter				Bioorg Med Chem Lett 12: 845-7 (2002) BindingDB Entry DOI: 10.7270/Q25M6515
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041293 (1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3ccccc3c1)N2C |THB:22:21:4.10.9:6.7,11:10:21:6.7,2:4:21:6.7| Show InChI InChI=1S/C21H25NO/c1-3-20(23)21-18(13-17-10-11-19(21)22(17)2)16-9-8-14-6-4-5-7-15(14)12-16/h4-9,12,17-19,21H,3,10-11,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.115	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.				J Med Chem 37: 1262-8 (1994) BindingDB Entry DOI: 10.7270/Q2TH8NBM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041293 (1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3ccccc3c1)N2C |THB:22:21:4.10.9:6.7,11:10:21:6.7,2:4:21:6.7| Show InChI InChI=1S/C21H25NO/c1-3-20(23)21-18(13-17-10-11-19(21)22(17)2)16-9-8-14-6-4-5-7-15(14)12-16/h4-9,12,17-19,21H,3,10-11,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [125I]-RTI-55 from dopamine transporter of rat brain membranes				J Med Chem 39: 2554-8 (1996) Article DOI: 10.1021/jm9600508 BindingDB Entry DOI: 10.7270/Q2V69HP1
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099235 (1-[3-(6-Methoxy-naphthalen-2-yl)-8-methyl-8-aza-bi...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3cc(OC)ccc3c1)N2C |TLB:24:23:4.10.9:6.7,THB:11:10:23:6.7,2:4:23:6.7| Show InChI InChI=1S/C22H27NO2/c1-4-21(24)22-19(13-17-8-10-20(22)23(17)2)16-6-5-15-12-18(25-3)9-7-14(15)11-16/h5-7,9,11-12,17,19-20,22H,4,8,10,13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.130	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099227 (1-[3-(6-Ethyl-naphthalen-2-yl)-8-methyl-8-aza-bicy...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3cc(CC)ccc3c1)N2C |TLB:24:23:4.10.9:6.7,THB:11:10:23:6.7,2:4:23:6.7| Show InChI InChI=1S/C23H29NO/c1-4-15-6-7-17-13-18(9-8-16(17)12-15)20-14-19-10-11-21(24(19)3)23(20)22(25)5-2/h6-9,12-13,19-21,23H,4-5,10-11,14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50021226 (CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CNC1CC(c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of noradrenaline uptake in rat synaptosomal fraction				J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50021226 (CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...) Show SMILES CNC1CC(c2ccccc12)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of 5-HT uptake in rat synaptosomal fraction				J Med Chem 28: 1817-28 (1986) BindingDB Entry DOI: 10.7270/Q29W0G1M
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099225 (2-Methyl-1-(8-methyl-3-naphthalen-2-yl-8-aza-bicyc...) Show SMILES CC(C)C(=O)C1C2CCC(CC1c1ccc3ccccc3c1)N2C |TLB:23:22:5.11.10:7.8,THB:3:5:22:7.8,12:11:22:7.8| Show InChI InChI=1S/C22H27NO/c1-14(2)22(24)21-19(13-18-10-11-20(21)23(18)3)17-9-8-15-6-4-5-7-16(15)12-17/h4-9,12,14,18-21H,10-11,13H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50055014 (7-(3,4-Dichloro-phenyl)-2,4,5,7-tetrahydro-3H-[1,3...) Show SMILES OC1(N2CCCCN=C2c2ccccc12)c1ccc(Cl)c(Cl)c1 |c:7| Show InChI InChI=1S/C18H16Cl2N2O/c19-15-8-7-12(11-16(15)20)18(23)14-6-2-1-5-13(14)17-21-9-3-4-10-22(17)18/h1-2,5-8,11,23H,3-4,9-10H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
Drew University Curated by ChEMBL					Assay Description Inhibition of [3H]-dopamine uptake at the dopamine transporter in rat striatal tissue				J Med Chem 39: 4935-41 (1997) Article DOI: 10.1021/jm960288w BindingDB Entry DOI: 10.7270/Q2ZK5FSR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041304 (1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...) Show SMILES CN1C2CCC1C(C(C2)c1ccc2ccccc2c1)C(C)=O |TLB:9:7:1:4.3,19:6:1:4.3,THB:0:1:6.7.8:4.3| Show InChI InChI=1S/C20H23NO/c1-13(22)20-18(12-17-9-10-19(20)21(17)2)16-8-7-14-5-3-4-6-15(14)11-16/h3-8,11,17-20H,9-10,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to dopamine transport sites in rat striatal membranes.				J Med Chem 37: 1262-8 (1994) BindingDB Entry DOI: 10.7270/Q2TH8NBM
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50043303 ((1-Benzo[b]thiophen-2-yl-cyclohexyl)-butyl-amine |...) Show SMILES CCCCNC1(CCCCC1)c1cc2ccccc2s1 Show InChI InChI=1S/C18H25NS/c1-2-3-13-19-18(11-7-4-8-12-18)17-14-15-9-5-6-10-16(15)20-17/h5-6,9-10,14,19H,2-4,7-8,11-13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrain				J Med Chem 36: 4075-81 (1994) BindingDB Entry DOI: 10.7270/Q2KK9CFJ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099228 (1-[3-(6-Iodo-naphthalen-2-yl)-8-methyl-8-aza-bicyc...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3cc(I)ccc3c1)N2C |TLB:23:22:4.10.9:6.7,THB:11:10:22:6.7,2:4:22:6.7| Show InChI InChI=1S/C21H24INO/c1-3-20(24)21-18(12-17-8-9-19(21)23(17)2)15-5-4-14-11-16(22)7-6-13(14)10-15/h4-7,10-11,17-19,21H,3,8-9,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035734 (CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...) Show SMILES [H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(I)cc1)C(=O)N1CCCC1)N2C |r,TLB:24:23:7.8.6:2.3| Show InChI InChI=1S/C19H25IN2O/c1-21-15-8-9-17(21)18(19(23)22-10-2-3-11-22)16(12-15)13-4-6-14(20)7-5-13/h4-7,15-18H,2-3,8-12H2,1H3/t15-,16+,17+,18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding at dopamine transporter was determined				J Med Chem 46: 1775-94 (2003) Article DOI: 10.1021/jm030092d BindingDB Entry DOI: 10.7270/Q2FF3T3J
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035734 (CHEMBL1643896 | RTI-229 | [3-(4-Iodo-phenyl)-8-met...) Show SMILES [H][C@]12CC[C@]([H])([C@H]([C@H](C1)c1ccc(I)cc1)C(=O)N1CCCC1)N2C |r,TLB:24:23:7.8.6:2.3| Show InChI InChI=1S/C19H25IN2O/c1-21-15-8-9-17(21)18(19(23)22-10-2-3-11-22)16(12-15)13-4-6-14(20)7-5-13/h4-7,15-18H,2-3,8-12H2,1H3/t15-,16+,17+,18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50111888 (1-[3-(3-Fluoro-4-iodo-phenyl)-8-methyl-8-aza-bicyc...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc(I)c(F)c1)N2C |TLB:20:19:4.10.9:6.7,THB:2:4:19:6.7| Show InChI InChI=1S/C17H21FINO/c1-3-16(21)17-12(9-11-5-7-15(17)20(11)2)10-4-6-14(19)13(18)8-10/h4,6,8,11-12,15,17H,3,5,7,9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Tested for the ability to displace [125I]- RTI-55 binding in rat striatal membrane against dopamine transporter				Bioorg Med Chem Lett 12: 845-7 (2002) BindingDB Entry DOI: 10.7270/Q25M6515
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099233 (1-[3-(6-Isopropyl-naphthalen-2-yl)-8-methyl-8-aza-...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3cc(ccc3c1)C(C)C)N2C |TLB:25:24:4.10.9:6.7,THB:11:10:24:6.7,2:4:24:6.7| Show InChI InChI=1S/C24H31NO/c1-5-23(26)24-21(14-20-10-11-22(24)25(20)4)19-9-8-17-12-16(15(2)3)6-7-18(17)13-19/h6-9,12-13,15,20-22,24H,5,10-11,14H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.390	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035725 (3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...) Show SMILES CC(C)OC(=O)C1C2CCC(CC1c1ccc(I)cc1)N2C |TLB:13:12:20:8.9,THB:4:6:20:8.9| Show InChI InChI=1S/C18H24INO2/c1-11(2)22-18(21)17-15(12-4-6-13(19)7-5-12)10-14-8-9-16(17)20(14)3/h4-7,11,14-17H,8-10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Wake Forest University Health Sciences Curated by ChEMBL					Assay Description Displacement of [125I]RTI-55 dopamine transporter binding in rat striatal membrane				Bioorg Med Chem Lett 15: 4915-8 (2005) Article DOI: 10.1016/j.bmcl.2005.08.028 BindingDB Entry DOI: 10.7270/Q2H41S7P
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50006784 (3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...) Show SMILES CC(C)OC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C |TLB:21:20:6.12.11:8.9,THB:4:6:20:8.9,13:12:20:8.9| Show InChI InChI=1S/C18H24INO2/c1-11(2)22-18(21)17-15(12-4-6-13(19)7-5-12)10-14-8-9-16(17)20(14)3/h4-7,11,14-17H,8-10H2,1-3H3/t14-,15-,16?,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporter				J Med Chem 37: 1220-3 (1994) BindingDB Entry DOI: 10.7270/Q2Z60PQ2
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50006784 (3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...) Show SMILES CC(C)OC(=O)[C@@H]1C2CC[C@H](C[C@@H]1c1ccc(I)cc1)N2C |TLB:21:20:6.12.11:8.9,THB:4:6:20:8.9,13:12:20:8.9| Show InChI InChI=1S/C18H24INO2/c1-11(2)22-18(21)17-15(12-4-6-13(19)7-5-12)10-14-8-9-16(17)20(14)3/h4-7,11,14-17H,8-10H2,1-3H3/t14-,15-,16?,17+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.430	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428l binding to Dopamine transporter				J Med Chem 35: 2497-500 (1992) BindingDB Entry DOI: 10.7270/Q2736RJC
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099223 (1-[3-(7-Iodo-naphthalen-2-yl)-8-methyl-8-aza-bicyc...) Show SMILES CCC(=O)C1C2CCC(CC1c1ccc3ccc(I)cc3c1)N2C |TLB:23:22:4.10.9:6.7,THB:11:10:22:6.7,2:4:22:6.7| Show InChI InChI=1S/C21H24INO/c1-3-20(24)21-18(12-17-8-9-19(21)23(17)2)14-5-4-13-6-7-16(22)11-15(13)10-14/h4-7,10-11,17-19,21H,3,8-9,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranes				J Med Chem 44: 1509-15 (2001) BindingDB Entry DOI: 10.7270/Q2H1318R
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50125902 ((1S,4R)-4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benz...) Show SMILES OC1CN(Cc2ccc(F)cc2)CC[C@@H]1CCOC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H30FNO2/c28-25-13-11-21(12-14-25)19-29-17-15-22(26(30)20-29)16-18-31-27(23-7-3-1-4-8-23)24-9-5-2-6-10-24/h1-14,22,26-27,30H,15-20H2/t22-,26?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Binding affinity towards dopamine transporter in rat striatum using [3H]WIN-35 428 as radioligand				J Med Chem 46: 1220-8 (2003) Article DOI: 10.1021/jm020275k BindingDB Entry DOI: 10.7270/Q2CZ37XT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50138651 (3-(4-Chloro-phenyl)-2-(3-ethyl-isoxazol-5-yl)-8-me...) Show SMILES CCc1cc(on1)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |THB:4:7:21:9.10,14:13:21:9.10| Show InChI InChI=1S/C19H23ClN2O/c1-3-14-10-18(23-21-14)19-16(12-4-6-13(20)7-5-12)11-15-8-9-17(19)22(15)2/h4-7,10,15-17,19H,3,8-9,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligand				J Med Chem 47: 296-302 (2004) Article DOI: 10.1021/jm030453p BindingDB Entry DOI: 10.7270/Q2VT1SVR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50052158 ((2S,5R)-3-(4-Chloro-phenyl)-8-methyl-2-(3-methyl-i...) Show SMILES CN1[C@@H]2CCC1[C@H](C(C2)c1ccc(Cl)cc1)c1cc(C)no1 |TLB:16:6:1:4.3,0:1:6.7.8:4.3,THB:9:7:1:4.3| Show InChI InChI=1S/C18H21ClN2O/c1-11-9-17(22-20-11)18-15(12-3-5-13(19)6-4-12)10-14-7-8-16(18)21(14)2/h3-6,9,14-16,18H,7-8,10H2,1-2H3/t14-,15?,16?,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatum				J Med Chem 39: 2753-63 (1996) Article DOI: 10.1021/jm960160e BindingDB Entry DOI: 10.7270/Q2N87BDF
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50138654 (3-(4-Chloro-phenyl)-8-methyl-2-(3-methyl-isoxazol-...) Show SMILES CN1C2CCC1C(C(C2)c1ccc(Cl)cc1)c1cc(C)no1 |TLB:16:6:1:4.3,9:7:1:4.3| Show InChI InChI=1S/C18H21ClN2O/c1-11-9-17(22-20-11)18-15(12-3-5-13(19)6-4-12)10-14-7-8-16(18)21(14)2/h3-6,9,14-16,18H,7-8,10H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.590	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligand				J Med Chem 47: 296-302 (2004) Article DOI: 10.1021/jm030453p BindingDB Entry DOI: 10.7270/Q2VT1SVR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50054754 (1-(2-Benzhydryloxy-ethyl)-4-((E)-3-phenyl-allyl)-[...) Show SMILES C(CN1CCCN(C\C=C\c2ccccc2)CC1)OC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H34N2O/c1-4-12-26(13-5-1)14-10-19-30-20-11-21-31(23-22-30)24-25-32-29(27-15-6-2-7-16-27)28-17-8-3-9-18-28/h1-10,12-18,29H,11,19-25H2/b14-10+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of dopamine DA reuptake				J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035747 (3-(4-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct...) Show SMILES CN1C2CCC1C(C(C2)c1ccc(I)cc1)C(=O)OC1CC1 |TLB:16:6:1:4.3,THB:9:7:1:4.3| Show InChI InChI=1S/C18H22INO2/c1-20-13-6-9-16(20)17(18(21)22-14-7-8-14)15(10-13)11-2-4-12(19)5-3-11/h2-5,13-17H,6-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50041282 ((3S,8R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]oc...) Show SMILES COC(=O)C1C2CCC(C[C@@H]1c1ccc(Cl)cc1)N2 |TLB:11:10:18:6.7,THB:2:4:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3/t11?,12-,13?,14?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporter				J Med Chem 37: 1220-3 (1994) BindingDB Entry DOI: 10.7270/Q2Z60PQ2
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporter				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporter				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C15H18ClNO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue				J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50005534 (1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...) Show SMILES C1CCN(CC1)C1(CCCCC1)c1cc2ccccc2s1 Show InChI InChI=1S/C19H25NS/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporter				J Med Chem 36: 1188-93 (1993) BindingDB Entry DOI: 10.7270/Q23F4Q98
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50453639 (CHEMBL2112889) Show SMILES [H][C@]12CCC(N1)[C@H]([C@H](C2)c1ccc(I)cc1)C(=O)OC |TLB:9:7:5:3.2,THB:16:6:5:3.2| Show InChI InChI=1S/C15H18INO2/c1-19-15(18)14-12(8-11-6-7-13(14)17-11)9-2-4-10(16)5-3-9/h2-5,11-14,17H,6-8H2,1H3/t11-,12-,13?,14+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to dopamine (DA) transporter				J Med Chem 37: 1220-3 (1994) BindingDB Entry DOI: 10.7270/Q2Z60PQ2
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50056569 (2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(Cc2cc3ccccc3[nH]2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-24-9-5-21(6-10-24)28(22-7-11-25(30)12-8-22)34-18-17-32-13-15-33(16-14-32)20-26-19-23-3-1-2-4-27(23)31-26/h1-12,19,28,31H,13-18,20H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity at the dopamine transporter using [125I]-RTI-55 in rat caudate membranes.				J Med Chem 40: 705-16 (1997) Article DOI: 10.1021/jm9606599 BindingDB Entry DOI: 10.7270/Q2XD10ST
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50054726 (CHEMBL423372 | [(S)-1-(2-Benzhydryloxy-ethyl)-pyrr...) Show SMILES C(CNC[C@@H]1CCCN1CCOC(c1ccccc1)c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C29H36N2O/c1-4-12-25(13-5-1)14-10-20-30-24-28-19-11-21-31(28)22-23-32-29(26-15-6-2-7-16-26)27-17-8-3-9-18-27/h1-9,12-13,15-18,28-30H,10-11,14,19-24H2/t28-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of dopamine DA reuptake				J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50052173 ((2S,5R)-3-(4-Iodo-phenyl)-8-methyl-2-(3-methyl-iso...) Show SMILES CN1[C@@H]2CCC1[C@H](C(C2)c1ccc(I)cc1)c1cc(C)no1 |TLB:16:6:1:4.3,0:1:6.7.8:4.3,THB:9:7:1:4.3| Show InChI InChI=1S/C18H21IN2O/c1-11-9-17(22-20-11)18-15(12-3-5-13(19)6-4-12)10-14-7-8-16(18)21(14)2/h3-6,9,14-16,18H,7-8,10H2,1-2H3/t14-,15?,16?,18+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity against Dopamine transporter using [3H]WIN-35 428 in rat striatum				J Med Chem 39: 2753-63 (1996) Article DOI: 10.1021/jm960160e BindingDB Entry DOI: 10.7270/Q2N87BDF
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50096914 (8-Methyl-3-(1-methyl-1H-indol-5-yl)-8-aza-bicyclo[...) Show SMILES CCOC(=O)C1C2CCC(CC1c1ccc3n(C)ccc3c1)N2C |THB:12:11:22:7.8,3:5:22:7.8| Show InChI InChI=1S/C20H26N2O2/c1-4-24-20(23)19-16(12-15-6-8-18(19)22(15)3)13-5-7-17-14(11-13)9-10-21(17)2/h5,7,9-11,15-16,18-19H,4,6,8,12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by ChEMBL					Assay Description Displacement of [125I]-RTI-55 from Dopamine transporter of rat striatal membrane				Bioorg Med Chem Lett 11: 487-9 (2001) BindingDB Entry DOI: 10.7270/Q2M907ZR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035758 (CHEMBL339763 | [3-(4-Iodo-phenyl)-8-methyl-8-aza-b...) Show SMILES CN1C2CCC1C(C(C2)c1ccc(I)cc1)C(=O)N1CCCO1 |TLB:16:6:1:4.3,THB:9:7:1:4.3| Show InChI InChI=1S/C18H23IN2O2/c1-20-14-7-8-16(20)17(18(22)21-9-2-10-23-21)15(11-14)12-3-5-13(19)6-4-12/h3-6,14-17H,2,7-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50138642 (3-(4-Chloro-phenyl)-2-isoxazol-5-yl-8-methyl-8-aza...) Show SMILES CN1C2CCC1C(C(C2)c1ccc(Cl)cc1)c1ccno1 |TLB:16:6:1:4.3,9:7:1:4.3| Show InChI InChI=1S/C17H19ClN2O/c1-20-13-6-7-15(20)17(16-8-9-19-21-16)14(10-13)11-2-4-12(18)5-3-11/h2-5,8-9,13-15,17H,6-7,10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibitory concentration required to inhibit dopamine transporter DAT was determined by using [3H]WIN-35428 radioligand				J Med Chem 47: 296-302 (2004) Article DOI: 10.1021/jm030453p BindingDB Entry DOI: 10.7270/Q2VT1SVR
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035730 (3-(3,4-Dichloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)c(Cl)c1)N2C |TLB:20:19:4.10.9:6.7,THB:11:10:19:6.7,2:4:19:6.7| Show InChI InChI=1S/C16H19Cl2NO2/c1-19-10-4-6-14(19)15(16(20)21-2)11(8-10)9-3-5-12(17)13(18)7-9/h3,5,7,10-11,14-15H,4,6,8H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50453398 (CHEMBL2373961) Show SMILES [H][C@@]12CCC(C([C@@H](C1)c1ccc(Cl)c(Cl)c1)C(=O)OC)N2C |r,TLB:8:6:3.2:20,THB:16:5:3.2:20| Show InChI InChI=1S/C16H19Cl2NO2/c1-19-10-4-6-14(19)15(16(20)21-2)11(8-10)9-3-5-12(17)13(18)7-9/h3,5,7,10-11,14-15H,4,6,8H2,1-2H3/t10-,11+,14?,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Concentration required to inhibit 50% of radioligand binding ([3H]WIN-35428) to the dopamine (DA) transporter in rat				J Med Chem 37: 2865-73 (1994) BindingDB Entry DOI: 10.7270/Q21C1XH0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50453398 (CHEMBL2373961) Show SMILES [H][C@@]12CCC(C([C@@H](C1)c1ccc(Cl)c(Cl)c1)C(=O)OC)N2C |r,TLB:8:6:3.2:20,THB:16:5:3.2:20| Show InChI InChI=1S/C16H19Cl2NO2/c1-19-10-4-6-14(19)15(16(20)21-2)11(8-10)9-3-5-12(17)13(18)7-9/h3,5,7,10-11,14-15H,4,6,8H2,1-2H3/t10-,11+,14?,15?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding at dopamine transporter was determined				J Med Chem 46: 1775-94 (2003) Article DOI: 10.1021/jm030092d BindingDB Entry DOI: 10.7270/Q2FF3T3J
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50127392 (3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...) Show SMILES COC(=O)C1C2CC[C@H](C[C@@H]1c1ccc(Cl)c(C)c1)N2C |THB:20:19:4.10.9:6.7,11:10:19:6.7,2:4:19:6.7| Show InChI InChI=1S/C17H22ClNO2/c1-10-8-11(4-6-14(10)18)13-9-12-5-7-15(19(12)2)16(13)17(20)21-3/h4,6,8,12-13,15-16H,5,7,9H2,1-3H3/t12-,13-,15?,16?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding at dopamine transporter was determined				J Med Chem 46: 1775-94 (2003) Article DOI: 10.1021/jm030092d BindingDB Entry DOI: 10.7270/Q2FF3T3J
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035764 (3-(4-Chloro-3-methyl-phenyl)-8-methyl-8-aza-bicycl...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(Cl)c(C)c1)N2C |TLB:11:10:19:6.7,THB:2:4:19:6.7| Show InChI InChI=1S/C17H22ClNO2/c1-10-8-11(4-6-14(10)18)13-9-12-5-7-15(19(12)2)16(13)17(20)21-3/h4,6,8,12-13,15-16H,5,7,9H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporter				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50093781 (3-p-Tolyl-8-aza-bicyclo[3.2.1]octane | 3-p-Tolyl-8...) Show SMILES COC(=O)C1C2CCC(CC1c1ccc(C)cc1)N2 |THB:2:4:18:6.7,11:10:18:6.7| Show InChI InChI=1S/C16H21NO2/c1-10-3-5-11(6-4-10)13-9-12-7-8-14(17-12)15(13)16(18)19-2/h3-6,12-15,17H,7-9H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat striatal dopamine transporter				J Med Chem 48: 3852-7 (2005) Article DOI: 10.1021/jm058164j BindingDB Entry DOI: 10.7270/Q2M909FV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50035765 (3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]o...) Show SMILES CON(C)C(=O)C1C2CCC(CC1c1ccc(Cl)cc1)N2C |TLB:13:12:20:8.9,THB:4:6:20:8.9| Show InChI InChI=1S/C17H23ClN2O2/c1-19-13-8-9-15(19)16(17(21)20(2)22-3)14(10-13)11-4-6-12(18)7-5-11/h4-7,13-16H,8-10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity at the Dopamine transporter in rat striata by inhibition of 0.5 nM [3H]WIN-35428 binding				J Med Chem 38: 379-88 (1995) BindingDB Entry DOI: 10.7270/Q2D50NM0
					More data for this Ligand-Target Pair

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