BindingDB PrimarySearch

Found 526 hits of ic50 for Cyclooxygenase-1
having polymerids = 2261,2299,50000093,50000760,50001408,50002157,50002608,50002633 and
complexids = 50014775,50014921
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247597 (4,5-Bis(4-methoxyphenyl)-3H-1,2-dithiol-3-one \| CH...) Show SMILES COc1ccc(cc1)-c1ssc(=O)c1-c1ccc(OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Tested for inhibition against Prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Università "La Sapienza" Curated by ChEMBL					Assay Description In vitro inhibitory activity against Prostaglandin G/H synthase 1 in murine J774 cells				J Med Chem 48: 3428-32 (2005) Article DOI: 10.1021/jm049121q BindingDB Entry DOI: 10.7270/Q2N01628
Università "La Sapienza" Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247826 (4,5-bis(4-methoxyphenyl)isothiazole \| CHEMBL473946) Show SMILES COc1ccc(cc1)-c1cnsc1-c1ccc(OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50474760 (CG-100649 \| CG100649 \| Polmacoxib) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
The M.S University of Baroda Curated by ChEMBL					Assay Description Inhibition of COX-1 in LPS-induced mouse peritoneal macrophages				Eur J Med Chem 162: 1-17 (2019) Article DOI: 10.1016/j.ejmech.2018.10.054 BindingDB Entry DOI: 10.7270/Q2FX7DSW
The M.S University of Baroda Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM13066 (2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...) Show SMILES OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Hamburg Curated by ChEMBL					Assay Description Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...				Bioorg Med Chem Lett 22: 5031-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.012 BindingDB Entry DOI: 10.7270/Q27P90GC
University of Hamburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247901 (4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiole-3-thi...) Show SMILES Cc1ccc(cc1)-c1ssc(=S)c1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245432 (4,5-Bis(4-methoxyphenyl)-1,2-selenazole \| CHEMBL47...) Show SMILES COc1ccc(cc1)-c1cn[se]c1-c1ccc(OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247827 (5-(4-methoxyphenyl)-4-p-tolylisothiazole \| CHEMBL5...) Show SMILES COc1ccc(cc1)-c1sncc1-c1ccc(C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245465 (5-(4-Chlorophenyl)-4-(4-methoxyphenyl)-1,2-selenaz...) Show SMILES COc1ccc(cc1)-c1cn[se]c1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247851 (4-(4-Chlorophenyl)-5-(4-methoxyphenyl)isothiazole ...) Show SMILES COc1ccc(cc1)-c1sncc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247578 (4-(4-Chlorophenyl)-5-p-tolyl-3H-1,2-dithiol-3-one ...) Show SMILES Cc1ccc(cc1)-c1ssc(=O)c1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245433 (5-(4-Methoxyphenyl)-4-p-tolyl-1,2-selenazole \| CHE...) Show SMILES COc1ccc(cc1)-c1[se]ncc1-c1ccc(C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245466 (4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-1,2-selenaz...) Show SMILES COc1ccc(cc1)-c1[se]ncc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247902 (4,5-bis(4-methoxyphenyl)-3H-1,2-dithiole-3-thione ...) Show SMILES COc1ccc(cc1)-c1ssc(=S)c1-c1ccc(OC)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247847 (5-(4-Chlorophenyl)-4-p-tolylisothiazole \| CHEMBL52...) Show SMILES Cc1ccc(cc1)-c1cnsc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137420 (2-[5-(4-Ethoxy-phenyl)-3-trifluoromethyl-pyrazol-1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245435 (4-(4-Chlorophenyl)-5-p-tolyl-1,2-selenazole \| CHEM...) Show SMILES Cc1ccc(cc1)-c1[se]ncc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247850 (5-(4-Chlorophenyl)-4-(4-methoxyphenyl)isothiazole ...) Show SMILES COc1ccc(cc1)-c1cnsc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50474774 (CHEMBL352430) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71.2	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
AmorePacific R&D Center Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50293280 (3-(4-(hydroxymethyl)phenyl)-4-(4-(methylsulfonyl)p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247849 (4,5-Bis(4-chlorophenyl)isothiazole \| CHEMBL491088) Show SMILES Clc1ccc(cc1)-c1cnsc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50179624 (5-(2,3-dimethylphenoxy)-1-(5-(methylsulfonyl)pyrid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50179602 (1-(5-(methylsulfonyl)pyridin-2-yl)-5-(5,6,7,8-tetr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094548 (1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094534 (1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094535 (1,3-diphenyl-4,7-dihydro-2H-isoindole \| CHEMBL1408...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094558 (3,5-Diphenyl-4-aza-tricyclo[5.2.1.02,6]deca-2,5-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094555 (5,6-Dimethyl-1,3-diphenyl-4,7-dihydro-2H-isoindole...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094540 (1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole \| CHE...) Show SMILES C1CCc2c(C1)c([nH]c2-c1ccccc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50293282 (CHEMBL504535 \| Imrecoxib) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX1 in mouse peritoneal macrophages				Bioorg Med Chem Lett 19: 2270-2 (2009) Article DOI: 10.1016/j.bmcl.2009.02.090 BindingDB Entry DOI: 10.7270/Q2CF9PZR
Chinese Academy of Medical Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50293282 (CHEMBL504535 \| Imrecoxib) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
PharmaPhase Co., Ltd Curated by ChEMBL					Assay Description Inhibition of calcimycin-induced COX-1 in peritoneal macrophage of C57BL/J6 mouse assessed as 6-Keto prostaglandin F1alpha formation preincubated for...				Bioorg Med Chem 22: 2005-32 (2014) Article DOI: 10.1016/j.bmc.2014.02.017 BindingDB Entry DOI: 10.7270/Q2WS8VS9
PharmaPhase Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50038649 (2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Hamburg Curated by ChEMBL					Assay Description Inhibition of bovine COX1 assessed as inhibition of calcium ionophore A23187-induced 12-hydroxyheptadecatrienoic acid formation by reverse-phase HPLC...				Bioorg Med Chem Lett 22: 5031-4 (2012) Article DOI: 10.1016/j.bmcl.2012.06.012 BindingDB Entry DOI: 10.7270/Q27P90GC
University of Hamburg Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50474742 (CHEMBL166295) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
AmorePacific R&D Center Curated by ChEMBL					Assay Description In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage method				J Med Chem 47: 792-804 (2004) Article DOI: 10.1021/jm020545z BindingDB Entry DOI: 10.7270/Q2QZ2DPG
AmorePacific R&D Center Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245436 (4,5-Bis(4-chlorophenyl)-1,2-selenazole \| CHEMBL501...) Show SMILES Clc1ccc(cc1)-c1cn[se]c1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50038649 (2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247577 (5-(4-Chlorophenyl)-4-p-tolyl-3H-1,2-dithiol-3-one ...) Show SMILES Cc1ccc(cc1)-c1c(ssc1=O)-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50247848 (4-(4-Chlorophenyl)-5-p-tolylisothiazole \| CHEMBL49...) Show SMILES Cc1ccc(cc1)-c1sncc1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-University Curated by ChEMBL					Assay Description Inhibition of COX1 in bovine platelets assessed as formation of 12-hydroxyheptadecatrienoic acid by HPLC				Bioorg Med Chem 17: 558-68 (2009) Article DOI: 10.1016/j.bmc.2008.11.074 BindingDB Entry DOI: 10.7270/Q2X92B4S
Johannes Gutenberg-University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50179609 (1-(5-(methylsulfonyl)pyridin-2-yl)-5-(phenylthio)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50179598 (1-(5-(methylsulfonyl)pyridin-2-yl)-5-(propylthio)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137411 (2-[3-Difluoromethyl-5-(4-methoxy-phenyl)-pyrazol-1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM50245434 (5-(4-Chlorophenyl)-4-p-tolyl-1,2-selenazole \| CHEM...) Show SMILES Cc1ccc(cc1)-c1cn[se]c1-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg University Curated by ChEMBL					Assay Description Inhibition of bovine COX1				Eur J Med Chem 43: 1152-9 (2008) Article DOI: 10.1016/j.ejmech.2007.09.007 BindingDB Entry DOI: 10.7270/Q2MG7QDR
Johannes Gutenberg University Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094551 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094546 (3,5-Diphenyl-4-aza-tricyclo[5.2.2.02,6]undeca-2,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM50094542 (1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...) Show SMILES C1Cc2c(C1)c([nH]c2-c1ccccc1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
Institut de Recherche Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50137423 (2-(4-Chloro-3-difluoromethyl-5-phenyl-pyrazol-1-yl...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Bos taurus)	BDBM22360 (2-(acetyloxy)benzoate \| 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by ChEMBL					Assay Description Inhibition of bovine COX-1 by enzyme immuno assay				Bioorg Med Chem Lett 19: 6855-61 (2009) Article DOI: 10.1016/j.bmcl.2009.10.083 BindingDB Entry DOI: 10.7270/Q2D79CB6
University of Alberta Curated by ChEMBL					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Canis familiaris)	BDBM50179596 (5-(cyclopentylmethoxy)-1-(5-(methylsulfonyl)pyridi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of COX1 by canine whole blood assay				Bioorg Med Chem Lett 16: 1202-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.110 BindingDB Entry DOI: 10.7270/Q2FT8KKM
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

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