Found 392 hits of ic50 data for polymerid = 2277,50000411 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50169743
((13S,17S)-13-Methyl-7-[9-(4,4,5,5,5-pentafluoro-pe...)Show SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc1cc(O)ccc31 |r| Show InChI InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Medical Center
Curated by ChEMBL
| Assay Description
Antagonist activity at ERalpha receptor in human MCF7 cells assessed as inhibition of cell growth after 6 days by crystal violet staining method |
J Med Chem 56: 2779-90 (2013)
Article DOI: 10.1021/jm3013773
BindingDB Entry DOI: 10.7270/Q2CC121G |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50212166
(7-chloro-6H-chromeno[4,3-b]quinoline-3,9-diol | CH...)Show InChI InChI=1S/C16H10ClNO3/c17-15-11-5-8(19)2-4-13(11)18-16-10-3-1-9(20)6-14(10)21-7-12(15)16/h1-6,19-20H,7H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM17292
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50212173
(7-bromo-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)Show InChI InChI=1S/C16H10BrNO3/c17-15-11-5-8(19)2-4-13(11)18-16-10-3-1-9(20)6-14(10)21-7-12(15)16/h1-6,19-20H,7H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501982
(CHEMBL4533857)Show SMILES COc1cc(\C=C(/C#N)C(N)=O)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H14F6N2O3/c1-30-17-7-11(6-13(9-27)18(28)29)2-5-16(17)31-10-12-3-4-14(19(21,22)23)8-15(12)20(24,25)26/h2-8H,10H2,1H3,(H2,28,29)/b13-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501984
(CHEMBL4578651)Show SMILES COCCNC(=O)C(=C\c1ccc(OCc2ccc(cc2C(F)(F)F)C(F)(F)F)c(OC)c1)\C#N Show InChI InChI=1S/C23H20F6N2O4/c1-33-8-7-31-21(32)16(12-30)9-14-3-6-19(20(10-14)34-2)35-13-15-4-5-17(22(24,25)26)11-18(15)23(27,28)29/h3-6,9-11H,7-8,13H2,1-2H3,(H,31,32)/b16-9+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50171724
(4-Bromo-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-bro...)Show InChI InChI=1S/C15H10BrNO2/c16-13-8-15(9-1-3-10(18)4-2-9)17-14-6-5-11(19)7-12(13)14/h1-8,18-19H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50171726
(4-Chloro-2-(4-hydroxy-phenyl)-quinolin-6-ol | 4-ch...)Show InChI InChI=1S/C15H10ClNO2/c16-13-8-15(9-1-3-10(18)4-2-9)17-14-6-5-11(19)7-12(13)14/h1-8,18-19H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501969
(CHEMBL4440692)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCOCCC(O)=O)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C25H22F6N2O6/c1-37-21-11-15(10-17(13-32)23(36)33-7-9-38-8-6-22(34)35)2-5-20(21)39-14-16-3-4-18(24(26,27)28)12-19(16)25(29,30)31/h2-5,10-12H,6-9,14H2,1H3,(H,33,36)(H,34,35)/b17-10+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276796
(CHEMBL4170306)Show SMILES CN1CCC[C@H]1CN1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O |r| Show InChI InChI=1S/C25H22ClF3N4O2S/c1-31-8-2-3-19(31)14-32-23(34)22(36-24(32)35)10-15-4-7-21-17(9-15)12-30-33(21)13-16-5-6-18(26)11-20(16)25(27,28)29/h4-7,9-12,19H,2-3,8,13-14H2,1H3/b22-10-/t19-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501980
(CHEMBL4467767)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C47H50F6N6O7S/c1-27-40(67-26-57-27)30-12-9-28(10-13-30)23-56-43(63)36-21-34(60)24-59(36)44(64)41(45(2,3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48,49)50)20-35(31)47(51,52)53/h9-16,18-20,26,34,36,41,60H,6-8,17,21,23-25H2,1-5H3,(H,55,62)(H,56,63)(H,58,61)/b32-18+/t34-,36-,41+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501986
(CHEMBL4543370)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCOCCOCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C49H54F6N6O9S/c1-29-42(71-28-59-29)32-9-6-30(7-10-32)25-58-45(65)38-23-36(62)26-61(38)46(66)43(47(2,3)4)60-41(63)14-16-68-18-19-69-17-15-57-44(64)34(24-56)20-31-8-13-39(40(21-31)67-5)70-27-33-11-12-35(48(50,51)52)22-37(33)49(53,54)55/h6-13,20-22,28,36,38,43,62H,14-19,23,25-27H2,1-5H3,(H,57,64)(H,58,65)(H,60,63)/b34-20+/t36-,38+,43-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501971
(CHEMBL4514580)Show SMILES COc1cc(\C=C(/C#N)C(O)=O)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H13F6NO4/c1-30-17-7-11(6-13(9-27)18(28)29)2-5-16(17)31-10-12-3-4-14(19(21,22)23)8-15(12)20(24,25)26/h2-8H,10H2,1H3,(H,28,29)/b13-6+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501985
(CHEMBL4445475)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C48H52F6N6O7S/c1-28-41(68-27-58-28)31-13-10-29(11-14-31)24-57-44(64)37-22-35(61)25-60(37)45(65)42(46(2,3)4)59-40(62)9-7-6-8-18-56-43(63)33(23-55)19-30-12-17-38(39(20-30)66-5)67-26-32-15-16-34(47(49,50)51)21-36(32)48(52,53)54/h10-17,19-21,27,35,37,42,61H,6-9,18,22,24-26H2,1-5H3,(H,56,63)(H,57,64)(H,59,62)/b33-19+/t35-,37+,42-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM17292
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H] Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Medical Center
Curated by ChEMBL
| Assay Description
Displacement of [3H]E2 from human recombinant ERalpha receptor after overnight incubation by liquid scintillation counting analysis |
J Med Chem 56: 2779-90 (2013)
Article DOI: 10.1021/jm3013773
BindingDB Entry DOI: 10.7270/Q2CC121G |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501973
(CHEMBL4444248)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCC(O)=O)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C25H22F6N2O5/c1-37-21-11-15(10-17(13-32)23(36)33-9-3-2-4-22(34)35)5-8-20(21)38-14-16-6-7-18(24(26,27)28)12-19(16)25(29,30)31/h5-8,10-12H,2-4,9,14H2,1H3,(H,33,36)(H,34,35)/b17-10+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50212172
(3,9-dihydroxy-6H-chromeno[4,3-b]quinoline-7-carbon...)Show InChI InChI=1S/C17H10N2O3/c18-7-13-12-5-9(20)2-4-15(12)19-17-11-3-1-10(21)6-16(11)22-8-14(13)17/h1-6,20-21H,8H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501975
(CHEMBL4456486)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C46H48F6N6O7S/c1-26-39(66-25-56-26)29-11-8-27(9-12-29)22-55-42(62)35-20-33(59)23-58(35)43(63)40(44(2,3)4)57-38(60)7-6-16-54-41(61)31(21-53)17-28-10-15-36(37(18-28)64-5)65-24-30-13-14-32(45(47,48)49)19-34(30)46(50,51)52/h8-15,17-19,25,33,35,40,59H,6-7,16,20,22-24H2,1-5H3,(H,54,61)(H,55,62)(H,57,60)/b31-17+/t33-,35+,40-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501979
(CHEMBL4521251)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCOCCOCCOCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C51H58F6N6O10S/c1-31-44(74-30-61-31)34-9-6-32(7-10-34)27-60-47(67)40-25-38(64)28-63(40)48(68)45(49(2,3)4)62-43(65)14-16-70-18-20-72-21-19-71-17-15-59-46(66)36(26-58)22-33-8-13-41(42(23-33)69-5)73-29-35-11-12-37(50(52,53)54)24-39(35)51(55,56)57/h6-13,22-24,30,38,40,45,64H,14-21,25,27-29H2,1-5H3,(H,59,66)(H,60,67)(H,62,65)/b36-22+/t38-,40+,45-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501974
(CHEMBL4461157)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C45H46F6N6O7S/c1-25-38(65-24-55-25)28-9-6-26(7-10-28)21-54-41(61)34-19-32(58)22-57(34)42(62)39(43(2,3)4)56-37(59)14-15-53-40(60)30(20-52)16-27-8-13-35(36(17-27)63-5)64-23-29-11-12-31(44(46,47)48)18-33(29)45(49,50)51/h6-13,16-18,24,32,34,39,58H,14-15,19,21-23H2,1-5H3,(H,53,60)(H,54,61)(H,56,59)/b30-16+/t32-,34+,39-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501978
(CHEMBL4532018)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C50H56F6N6O7S/c1-30-43(70-29-60-30)33-15-12-31(13-16-33)26-59-46(66)39-24-37(63)27-62(39)47(67)44(48(2,3)4)61-42(64)11-9-7-6-8-10-20-58-45(65)35(25-57)21-32-14-19-40(41(22-32)68-5)69-28-34-17-18-36(49(51,52)53)23-38(34)50(54,55)56/h12-19,21-23,29,37,39,44,63H,6-11,20,24,26-28H2,1-5H3,(H,58,65)(H,59,66)(H,61,64)/b35-21+/t37-,39+,44-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276803
(CHEMBL4169272)Show SMILES COc1ccc(Cn2ncc3cc(\C=C4/SC(=O)N(CCN5CCOCC5)C4=O)ccc23)c(c1)C(F)(F)F Show InChI InChI=1S/C26H25F3N4O4S/c1-36-20-4-3-18(21(14-20)26(27,28)29)16-33-22-5-2-17(12-19(22)15-30-33)13-23-24(34)32(25(35)38-23)7-6-31-8-10-37-11-9-31/h2-5,12-15H,6-11,16H2,1H3/b23-13- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501981
(CHEMBL4218019)Show SMILES COc1cc(\C=C2/SC(=O)N(CCOCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)C2=O)ccc1Oc1ccc(cc1C(F)(F)F)C#N |r| Show InChI InChI=1S/C46H47F3N6O9S2/c1-26-39(65-25-52-26)30-10-6-27(7-11-30)23-51-41(58)33-21-31(56)24-55(33)43(60)40(45(2,3)4)53-38(57)14-16-63-17-15-54-42(59)37(66-44(54)61)20-28-8-13-35(36(19-28)62-5)64-34-12-9-29(22-50)18-32(34)46(47,48)49/h6-13,18-20,25,31,33,40,56H,14-17,21,23-24H2,1-5H3,(H,51,58)(H,53,57)/b37-20-/t31-,33+,40-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276818
(CHEMBL4161346)Show SMILES COc1ccc(Cn2ncc3cc(\C=C4/SC(=O)N(C5CCC(CC5)C(O)=O)C4=O)ccc23)c(c1)C(F)(F)F |(9.02,-29.93,;9.49,-28.47,;8.46,-27.32,;8.94,-25.85,;7.91,-24.71,;6.41,-25.04,;5.38,-23.89,;5.86,-22.43,;4.95,-21.18,;5.86,-19.94,;7.32,-20.41,;8.65,-19.64,;9.99,-20.4,;11.32,-19.63,;12.66,-20.39,;12.82,-21.92,;14.33,-22.24,;14.96,-23.64,;15.09,-20.9,;16.62,-20.73,;17.53,-21.98,;19.05,-21.81,;19.68,-20.41,;18.77,-19.16,;17.23,-19.32,;21.21,-20.24,;22.12,-21.49,;21.84,-18.83,;14.06,-19.76,;14.37,-18.25,;9.99,-21.95,;8.66,-22.72,;7.32,-21.95,;5.93,-26.49,;6.95,-27.64,;4.41,-26.8,;3.04,-27.09,;3.16,-25.79,;3.67,-28.23,)| Show InChI InChI=1S/C27H24F3N3O5S/c1-38-20-8-5-17(21(12-20)27(28,29)30)14-32-22-9-2-15(10-18(22)13-31-32)11-23-24(34)33(26(37)39-23)19-6-3-16(4-7-19)25(35)36/h2,5,8-13,16,19H,3-4,6-7,14H2,1H3,(H,35,36)/b23-11- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276805
(CHEMBL4166492)Show SMILES CC(=O)NS(=O)(=O)CN1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O Show InChI InChI=1S/C22H16ClF3N4O5S2/c1-12(31)28-37(34,35)11-29-20(32)19(36-21(29)33)7-13-2-5-18-15(6-13)9-27-30(18)10-14-3-4-16(23)8-17(14)22(24,25)26/h2-9H,10-11H2,1H3,(H,28,31)/b19-7- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276817
(CHEMBL4159613)Show SMILES OC(=O)CN1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O Show InChI InChI=1S/C21H13ClF3N3O4S/c22-14-3-2-12(15(7-14)21(23,24)25)9-28-16-4-1-11(5-13(16)8-26-28)6-17-19(31)27(10-18(29)30)20(32)33-17/h1-8H,9-10H2,(H,29,30)/b17-6- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276834
(CHEMBL4163909)Show SMILES COc1ccc(Cn2ncc3cc(\C=C4/SC(=O)N(CC(O)=O)C4=O)ccc23)c(c1)C(F)(F)F Show InChI InChI=1S/C22H16F3N3O5S/c1-33-15-4-3-13(16(8-15)22(23,24)25)10-28-17-5-2-12(6-14(17)9-26-28)7-18-20(31)27(11-19(29)30)21(32)34-18/h2-9H,10-11H2,1H3,(H,29,30)/b18-7- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501983
(CHEMBL4538025)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCOCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C47H50F6N6O8S/c1-27-40(68-26-57-27)30-9-6-28(7-10-30)23-56-43(63)36-21-34(60)24-59(36)44(64)41(45(2,3)4)58-39(61)14-16-66-17-15-55-42(62)32(22-54)18-29-8-13-37(38(19-29)65-5)67-25-31-11-12-33(46(48,49)50)20-35(31)47(51,52)53/h6-13,18-20,26,34,36,41,60H,14-17,21,23-25H2,1-5H3,(H,55,62)(H,56,63)(H,58,61)/b32-18+/t34-,36+,41-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM19459
(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501970
(CHEMBL4461263)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCOCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C46H48F6N6O8S/c1-26-39(67-25-56-26)29-9-6-27(7-10-29)21-55-42(62)35-19-33(59)22-58(35)43(63)40(44(2,3)4)57-38(60)24-65-15-14-54-41(61)31(20-53)16-28-8-13-36(37(17-28)64-5)66-23-30-11-12-32(45(47,48)49)18-34(30)46(50,51)52/h6-13,16-18,25,33,35,40,59H,14-15,19,21-24H2,1-5H3,(H,54,61)(H,55,62)(H,57,60)/b31-16+/t33-,35+,40-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276816
(CHEMBL4166832)Show SMILES OC(=O)C1CCC(CC1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O |(47.59,-35.76,;46.69,-34.51,;47.31,-33.11,;45.15,-34.68,;44.52,-36.09,;43,-36.25,;42.09,-35,;42.71,-33.59,;44.24,-33.43,;40.57,-35.17,;39.8,-36.51,;40.43,-37.91,;38.29,-36.19,;38.13,-34.66,;36.79,-33.9,;35.46,-34.67,;35.47,-36.22,;34.13,-37,;32.79,-36.23,;31.33,-36.7,;30.85,-38.16,;31.88,-39.31,;33.38,-38.98,;34.41,-40.12,;33.94,-41.59,;34.97,-42.74,;32.43,-41.91,;31.4,-40.77,;29.88,-41.08,;28.51,-41.36,;28.63,-40.06,;29.14,-42.51,;30.43,-35.45,;31.33,-34.21,;32.8,-34.69,;34.12,-33.91,;39.53,-34.03,;39.84,-32.52,)| Show InChI InChI=1S/C26H21ClF3N3O4S/c27-18-5-2-16(20(11-18)26(28,29)30)13-32-21-8-1-14(9-17(21)12-31-32)10-22-23(34)33(25(37)38-22)19-6-3-15(4-7-19)24(35)36/h1-2,5,8-12,15,19H,3-4,6-7,13H2,(H,35,36)/b22-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501977
(CHEMBL4469374)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C49H54F6N6O7S/c1-29-42(69-28-59-29)32-14-11-30(12-15-32)25-58-45(65)38-23-36(62)26-61(38)46(66)43(47(2,3)4)60-41(63)10-8-6-7-9-19-57-44(64)34(24-56)20-31-13-18-39(40(21-31)67-5)68-27-33-16-17-35(48(50,51)52)22-37(33)49(53,54)55/h11-18,20-22,28,36,38,43,62H,6-10,19,23,25-27H2,1-5H3,(H,57,64)(H,58,65)(H,60,63)/b34-20+/t36-,38+,43-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50336739
(4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-meth...)Show SMILES COC(=O)c1ccc(Oc2ccc(C=C3SC(O)=NC3=O)cc2OC)c2ccccc12 |w:13.12,c:17| Show InChI InChI=1S/C23H17NO6S/c1-28-19-11-13(12-20-21(25)24-23(27)31-20)7-9-18(19)30-17-10-8-16(22(26)29-2)14-5-3-4-6-15(14)17/h3-12H,1-2H3,(H,24,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at 6his-tagged ERRalpha LBD assessed as inhibition of recruitment of GST-labeled coactivator Scr2 by TR-FRET assay |
J Med Chem 54: 788-808 (2012)
Article DOI: 10.1021/jm101063h
BindingDB Entry DOI: 10.7270/Q208668Q |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501976
(CHEMBL4570799)Show SMILES COc1cc(\C=C(/C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C47H50F6N6O7S/c1-27-40(67-26-57-27)30-12-9-28(10-13-30)23-56-43(63)36-21-34(60)24-59(36)44(64)41(45(2,3)4)58-39(61)8-6-7-17-55-42(62)32(22-54)18-29-11-16-37(38(19-29)65-5)66-25-31-14-15-33(46(48,49)50)20-35(31)47(51,52)53/h9-16,18-20,26,34,36,41,60H,6-8,17,21,23-25H2,1-5H3,(H,55,62)(H,56,63)(H,58,61)/b32-18+/t34-,36+,41-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276822
(CHEMBL4165363)Show SMILES FC(F)(F)c1cc(Cl)ccc1Cn1ncc2cc(\C=C3/SC(=O)N(Cc4nnn[nH]4)C3=O)ccc12 Show InChI InChI=1S/C21H13ClF3N7O2S/c22-14-3-2-12(15(7-14)21(23,24)25)9-32-16-4-1-11(5-13(16)8-26-32)6-17-19(33)31(20(34)35-17)10-18-27-29-30-28-18/h1-8H,9-10H2,(H,27,28,29,30)/b17-6- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276830
(CHEMBL4172209)Show SMILES OCCN1CCC(CC1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O Show InChI InChI=1S/C26H24ClF3N4O3S/c27-19-3-2-17(21(13-19)26(28,29)30)15-33-22-4-1-16(11-18(22)14-31-33)12-23-24(36)34(25(37)38-23)20-5-7-32(8-6-20)9-10-35/h1-4,11-14,20,35H,5-10,15H2/b23-12- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276811
(CHEMBL4172522)Show SMILES FC(F)(F)c1cc(Cl)ccc1Cn1ncc2cc(\C=C3/SC(=O)N(C[C@H]4COCCN4)C3=O)ccc12 |r| Show InChI InChI=1S/C24H20ClF3N4O3S/c25-17-3-2-15(19(9-17)24(26,27)28)11-32-20-4-1-14(7-16(20)10-30-32)8-21-22(33)31(23(34)36-21)12-18-13-35-6-5-29-18/h1-4,7-10,18,29H,5-6,11-13H2/b21-8-/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50336759
(4-[4-(2,4-Dioxothiazolidin-5-ylidenemethyl)-2-meth...)Show SMILES COC(=O)c1ccc(Oc2ccc(C=C3SC(O)=NC3=O)cc2OC)c(c1)C(F)(F)F |w:13.12,c:17| Show InChI InChI=1S/C20H14F3NO6S/c1-28-15-7-10(8-16-17(25)24-19(27)31-16)3-5-14(15)30-13-6-4-11(18(26)29-2)9-12(13)20(21,22)23/h3-9H,1-2H3,(H,24,25,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description
Antagonist activity at 6his-tagged ERRalpha LBD assessed as inhibition of recruitment of GST-labeled coactivator Scr2 by TR-FRET assay |
J Med Chem 54: 788-808 (2012)
Article DOI: 10.1021/jm101063h
BindingDB Entry DOI: 10.7270/Q208668Q |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276814
(CHEMBL4163054)Show SMILES FC(F)(F)c1cc(Cl)ccc1Cn1ncc2cc(\C=C3/SC(=O)N(C4CCNCC4)C3=O)ccc12 Show InChI InChI=1S/C24H20ClF3N4O2S/c25-17-3-2-15(19(11-17)24(26,27)28)13-31-20-4-1-14(9-16(20)12-30-31)10-21-22(33)32(23(34)35-21)18-5-7-29-8-6-18/h1-4,9-12,18,29H,5-8,13H2/b21-10- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276795
(CHEMBL4163375)Show SMILES FC(F)(F)c1cc(Cl)ccc1Cn1ncc2cc(\C=C3/SC(=O)N(CCN4CCCC4)C3=O)ccc12 Show InChI InChI=1S/C25H22ClF3N4O2S/c26-19-5-4-17(20(13-19)25(27,28)29)15-33-21-6-3-16(11-18(21)14-30-33)12-22-23(34)32(24(35)36-22)10-9-31-7-1-2-8-31/h3-6,11-14H,1-2,7-10,15H2/b22-12- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276835
(CHEMBL4173278)Show SMILES CS(=O)(=O)NC(=O)CN1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O Show InChI InChI=1S/C22H16ClF3N4O5S2/c1-37(34,35)28-19(31)11-29-20(32)18(36-21(29)33)7-12-2-5-17-14(6-12)9-27-30(17)10-13-3-4-15(23)8-16(13)22(24,25)26/h2-9H,10-11H2,1H3,(H,28,31)/b18-7- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276823
(CHEMBL4177113)Show SMILES NS(=O)(=O)NC(=O)CN1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O Show InChI InChI=1S/C21H15ClF3N5O5S2/c22-14-3-2-12(15(7-14)21(23,24)25)9-30-16-4-1-11(5-13(16)8-27-30)6-17-19(32)29(20(33)36-17)10-18(31)28-37(26,34)35/h1-8H,9-10H2,(H,28,31)(H2,26,34,35)/b17-6- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276836
(CHEMBL4173757)Show SMILES CN1CCC(CC1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O Show InChI InChI=1S/C25H22ClF3N4O2S/c1-31-8-6-19(7-9-31)33-23(34)22(36-24(33)35)11-15-2-5-21-17(10-15)13-30-32(21)14-16-3-4-18(26)12-20(16)25(27,28)29/h2-5,10-13,19H,6-9,14H2,1H3/b22-11- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50501972
(CHEMBL4443118)Show SMILES COC(=O)C(=C\c1ccc(OCc2ccc(cc2C(F)(F)F)C(F)(F)F)c(OC)c1)\C#N Show InChI InChI=1S/C21H15F6NO4/c1-30-18-8-12(7-14(10-28)19(29)31-2)3-6-17(18)32-11-13-4-5-15(20(22,23)24)9-16(13)21(25,26)27/h3-9H,11H2,1-2H3/b14-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Binding affinity to GST-tagged ERRalpha-LBD (unknown origin) using fluorescein-conjugated coactivator PGC-1alpha incubated for 1 hr by TR-FRET assay |
ACS Med Chem Lett 10: 767-772 (2019)
Article DOI: 10.1021/acsmedchemlett.9b00025
BindingDB Entry DOI: 10.7270/Q2S185QM |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50434093
(CHEMBL2381353)Show InChI InChI=1S/C18H18N4O/c1-12(2)13-6-5-7-14(10-13)22-11-17(20-21-22)18(23)15-8-3-4-9-16(15)19/h3-12H,19H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human GAL4-DBD-fused ERRalpha-LBD transcriptional activity transfected in human 293FT cells assessed as disruption of interaction with ... |
J Med Chem 56: 4631-40 (2013)
Article DOI: 10.1021/jm4003928
BindingDB Entry DOI: 10.7270/Q2GX4CZW |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50232195
(CHEMBL4093786)Show SMILES COCCOc1cccc(Cn2nc(C)c3cc(sc23)C(=O)N2CCN([C@H](C)C2)c2ccc(cn2)C(C)=O)c1 |r| Show InChI InChI=1S/C29H33N5O4S/c1-19-17-32(10-11-33(19)27-9-8-23(16-30-27)21(3)35)28(36)26-15-25-20(2)31-34(29(25)39-26)18-22-6-5-7-24(14-22)38-13-12-37-4/h5-9,14-16,19H,10-13,17-18H2,1-4H3/t19-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
| Assay Description
Inverse agonist activity at GAL4-fused human ERRalpha expressed in HEK293 cells assessed as inhibition of transcriptional activity after 20 hrs by lu... |
Bioorg Med Chem Lett 27: 1145-1148 (2017)
Article DOI: 10.1016/j.bmcl.2017.01.076
BindingDB Entry DOI: 10.7270/Q22B9183 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50212161
(7-vinyl-6H-chromeno[4,3-b]quinoline-3,9-diol | CHE...)Show InChI InChI=1S/C18H13NO3/c1-2-12-14-7-10(20)4-6-16(14)19-18-13-5-3-11(21)8-17(13)22-9-15(12)18/h2-8,20-21H,1,9H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human ERalpha |
Bioorg Med Chem Lett 17: 4053-6 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.068
BindingDB Entry DOI: 10.7270/Q2V124HV |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276812
(CHEMBL4164196)Show SMILES CN1CC[C@@H]([C@@H](F)C1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O |r| Show InChI InChI=1S/C25H21ClF4N4O2S/c1-32-7-6-21(19(27)13-32)34-23(35)22(37-24(34)36)9-14-2-5-20-16(8-14)11-31-33(20)12-15-3-4-17(26)10-18(15)25(28,29)30/h2-5,8-11,19,21H,6-7,12-13H2,1H3/b22-9-/t19-,21-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276797
(CHEMBL4174856)Show SMILES CN1CC[C@H]([C@H](F)C1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O |r| Show InChI InChI=1S/C25H21ClF4N4O2S/c1-32-7-6-21(19(27)13-32)34-23(35)22(37-24(34)36)9-14-2-5-20-16(8-14)11-31-33(20)12-15-3-4-17(26)10-18(15)25(28,29)30/h2-5,8-11,19,21H,6-7,12-13H2,1H3/b22-9-/t19-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
Steroid hormone receptor ERR1
(Homo sapiens (Human)) | BDBM50276833
(CHEMBL4175927)Show SMILES CN1CC[C@H]([C@H](O)C1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O |r| Show InChI InChI=1S/C25H22ClF3N4O3S/c1-31-7-6-20(21(34)13-31)33-23(35)22(37-24(33)36)9-14-2-5-19-16(8-14)11-30-32(19)12-15-3-4-17(26)10-18(15)25(27,28)29/h2-5,8-11,20-21,34H,6-7,12-13H2,1H3/b22-9-/t20-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research and Development LLC
Curated by ChEMBL
| Assay Description
Antagonist activity at His6-tagged ERRalpha LBD (unknown origin) assessed as inhibition of GST-tagged SRC-2 co-activator peptide recruitment after 18... |
Eur J Med Chem 138: 830-853 (2017)
Article DOI: 10.1016/j.ejmech.2017.07.015
BindingDB Entry DOI: 10.7270/Q2W098F7 |
More data for this
Ligand-Target Pair | |
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