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Compile Data Set for Download or QSAR

Found 33 hits of kd data for polymerid = 2288   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50414792
PNG
(CHEMBL573817)
Show SMILES C(CN1CCCCC1)C#Cc1cccc(CN2CCCCC2)c1
Show InChI InChI=1S/C21H30N2/c1-4-13-22(14-5-1)15-8-3-10-20-11-9-12-21(18-20)19-23-16-6-2-7-17-23/h9,11-12,18H,1-2,4-8,13-17,19H2
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n/an/an/a 0.0813n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP accumulation treate...


Eur J Med Chem 44: 4098-106 (2009)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410347
PNG
(CHEMBL194441)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C20H32N2O/c1-17(2)22-14-10-20(11-15-22)23-19-8-6-18(7-9-19)16-21-12-4-3-5-13-21/h6-9,17,20H,3-5,10-16H2,1-2H3
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n/an/an/a 0.126n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50159110
PNG
(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1
Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2
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n/an/an/a 0.145n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50159110
PNG
(1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piper...)
Show SMILES C(COc1ccc(CN2CCCCC2)cc1)CN1CCCCC1
Show InChI InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2
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n/an/an/a 0.145n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor


J Med Chem 46: 3938-44 (2003)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50200636
PNG
(1-(4-(4-(piperidin-1-ylmethyl)phenyl)but-3-ynyl)pi...)
Show SMILES C(CN1CCCCC1)C#Cc1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C21H30N2/c1-4-14-22(15-5-1)16-8-3-9-20-10-12-21(13-11-20)19-23-17-6-2-7-18-23/h10-13H,1-2,4-8,14-19H2
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n/an/an/a 0.148n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP accumulation treate...


Eur J Med Chem 44: 4098-106 (2009)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410329
PNG
(CHEMBL427177)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCCCCC2)cc1
Show InChI InChI=1S/C21H34N2O/c1-18(2)23-15-11-21(12-16-23)24-20-9-7-19(8-10-20)17-22-13-5-3-4-6-14-22/h7-10,18,21H,3-6,11-17H2,1-2H3
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n/an/an/a 0.174n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50409727
PNG
(CHEMBL129411)
Show SMILES C(COc1ccc(CNC2CCCCC2)cc1)CN1CCCCC1
Show InChI InChI=1S/C21H34N2O/c1-3-8-20(9-4-1)22-18-19-10-12-21(13-11-19)24-17-7-16-23-14-5-2-6-15-23/h10-13,20,22H,1-9,14-18H2
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n/an/an/a 0.195n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor


J Med Chem 46: 3938-44 (2003)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410335
PNG
(CHEMBL193381)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN(C)CCN(C)C)cc1
Show InChI InChI=1S/C20H35N3O/c1-17(2)23-12-10-20(11-13-23)24-19-8-6-18(7-9-19)16-22(5)15-14-21(3)4/h6-9,17,20H,10-16H2,1-5H3
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n/an/an/a 0.214n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50375373
PNG
(CHEMBL129306)
Show SMILES OC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1
Show InChI InChI=1S/C20H32N2O2/c23-19-9-14-22(15-10-19)17-18-5-7-20(8-6-18)24-16-4-13-21-11-2-1-3-12-21/h5-8,19,23H,1-4,9-17H2
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n/an/an/a 0.229n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor


J Med Chem 46: 3938-44 (2003)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410326
PNG
(CHEMBL194541)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCC(CO)CC2)cc1
Show InChI InChI=1S/C21H34N2O2/c1-17(2)23-13-9-21(10-14-23)25-20-5-3-18(4-6-20)15-22-11-7-19(16-24)8-12-22/h3-6,17,19,21,24H,7-16H2,1-2H3
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n/an/an/a 0.257n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410346
PNG
(CHEMBL372471)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCN(C)CC2)cc1
Show InChI InChI=1S/C20H33N3O/c1-17(2)23-10-8-20(9-11-23)24-19-6-4-18(5-7-19)16-22-14-12-21(3)13-15-22/h4-7,17,20H,8-16H2,1-3H3
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n/an/an/a 0.257n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410344
PNG
(CHEMBL195815)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCCN(C)CC2)cc1
Show InChI InChI=1S/C21H35N3O/c1-18(2)24-13-9-21(10-14-24)25-20-7-5-19(6-8-20)17-23-12-4-11-22(3)15-16-23/h5-8,18,21H,4,9-17H2,1-3H3
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n/an/an/a 0.324n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410338
PNG
(CHEMBL193934)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCC(O)CC2)cc1
Show InChI InChI=1S/C20H32N2O2/c1-16(2)22-13-9-20(10-14-22)24-19-5-3-17(4-6-19)15-21-11-7-18(23)8-12-21/h3-6,16,18,20,23H,7-15H2,1-2H3
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n/an/an/a 0.331n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410339
PNG
(CHEMBL439676)
Show SMILES CCCCN(C)Cc1ccc(OC2CCN(CC2)C(C)C)cc1
Show InChI InChI=1S/C20H34N2O/c1-5-6-13-21(4)16-18-7-9-19(10-8-18)23-20-11-14-22(15-12-20)17(2)3/h7-10,17,20H,5-6,11-16H2,1-4H3
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n/an/an/a 0.339n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410333
PNG
(CHEMBL370169)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCCC2)cc1
Show InChI InChI=1S/C19H30N2O/c1-16(2)21-13-9-19(10-14-21)22-18-7-5-17(6-8-18)15-20-11-3-4-12-20/h5-8,16,19H,3-4,9-15H2,1-2H3
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n/an/an/a 0.355n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410341
PNG
(CHEMBL195826)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CNC2CC2)cc1
Show InChI InChI=1S/C18H28N2O/c1-14(2)20-11-9-18(10-12-20)21-17-7-3-15(4-8-17)13-19-16-5-6-16/h3-4,7-8,14,16,18-19H,5-6,9-13H2,1-2H3
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n/an/an/a 0.457n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410330
PNG
(CHEMBL191405)
Show SMILES CCN(CC)Cc1ccc(OC2CCN(CC2)C(C)C)cc1
Show InChI InChI=1S/C19H32N2O/c1-5-20(6-2)15-17-7-9-18(10-8-17)22-19-11-13-21(14-12-19)16(3)4/h7-10,16,19H,5-6,11-15H2,1-4H3
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n/an/an/a 0.468n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50217581
PNG
(4-(4-(1-isopropylpiperidin-4-yloxy)benzyl)morpholi...)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C19H30N2O2/c1-16(2)21-9-7-19(8-10-21)23-18-5-3-17(4-6-18)15-20-11-13-22-14-12-20/h3-6,16,19H,7-15H2,1-2H3
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n/an/an/a 0.479n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50217569
PNG
(4-(3-(4-(piperidin-1-yl)but-1-ynyl)benzyl)morpholi...)
Show SMILES C(CN1CCCCC1)C#Cc1cccc(CN2CCOCC2)c1
Show InChI InChI=1S/C20H28N2O/c1-3-10-21(11-4-1)12-5-2-7-19-8-6-9-20(17-19)18-22-13-15-23-16-14-22/h6,8-9,17H,1,3-5,10-16,18H2
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n/an/an/a 0.490n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP accumulation treate...


Eur J Med Chem 44: 4098-106 (2009)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50409730
PNG
(CHEMBL339867)
Show SMILES C(COc1ccc(CN2CCOCC2)cc1)CN1CCCCC1
Show InChI InChI=1S/C19H30N2O2/c1-2-9-20(10-3-1)11-4-14-23-19-7-5-18(6-8-19)17-21-12-15-22-16-13-21/h5-8H,1-4,9-17H2
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n/an/an/a 0.537n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor


J Med Chem 46: 3938-44 (2003)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410337
PNG
(CHEMBL194090)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCN(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C26H37N3O/c1-22(2)29-14-12-26(13-15-29)30-25-10-8-24(9-11-25)21-28-18-16-27(17-19-28)20-23-6-4-3-5-7-23/h3-11,22,26H,12-21H2,1-2H3
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n/an/an/a 0.661n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410336
PNG
(CHEMBL372935)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CNc2ccccn2)cc1
Show InChI InChI=1S/C20H27N3O/c1-16(2)23-13-10-19(11-14-23)24-18-8-6-17(7-9-18)15-22-20-5-3-4-12-21-20/h3-9,12,16,19H,10-11,13-15H2,1-2H3,(H,21,22)
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n/an/an/a 0.741n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410340
PNG
(CHEMBL195099)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCC(Cc3ccccc3)CC2)cc1
Show InChI InChI=1S/C27H38N2O/c1-22(2)29-18-14-27(15-19-29)30-26-10-8-25(9-11-26)21-28-16-12-24(13-17-28)20-23-6-4-3-5-7-23/h3-11,22,24,27H,12-21H2,1-2H3
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n/an/an/a 0.813n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410331
PNG
(CHEMBL193861)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN2CCN(CC2)c2ccccc2)cc1
Show InChI InChI=1S/C25H35N3O/c1-21(2)27-14-12-25(13-15-27)29-24-10-8-22(9-11-24)20-26-16-18-28(19-17-26)23-6-4-3-5-7-23/h3-11,21,25H,12-20H2,1-2H3
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n/an/an/a 1.02n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410343
PNG
(CHEMBL191992)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CN(C)C)cc1
Show InChI InChI=1S/C17H28N2O/c1-14(2)19-11-9-17(10-12-19)20-16-7-5-15(6-8-16)13-18(3)4/h5-8,14,17H,9-13H2,1-4H3
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n/an/an/a 1.17n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410354
PNG
(CHEMBL195777)
Show SMILES Cc1ccc2nc(cn2c1)-c1ccc(OCCCN2CCCCC2)cc1
Show InChI InChI=1S/C22H27N3O/c1-18-6-11-22-23-21(17-25(22)16-18)19-7-9-20(10-8-19)26-15-5-14-24-12-3-2-4-13-24/h6-11,16-17H,2-5,12-15H2,1H3
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n/an/an/a 2.04n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50410345
PNG
(CHEMBL194548)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc(CNc2ccccc2)cc1
Show InChI InChI=1S/C21H28N2O/c1-17(2)23-14-12-21(13-15-23)24-20-10-8-18(9-11-20)16-22-19-6-4-3-5-7-19/h3-11,17,21-22H,12-16H2,1-2H3
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n/an/an/a 2.69n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50414793
PNG
(CHEMBL573090)
Show SMILES C(CN1CCCCC1)C#Cc1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C20H28N2O/c1-3-11-21(12-4-1)13-5-2-6-19-7-9-20(10-8-19)18-22-14-16-23-17-15-22/h7-10H,1,3-5,11-18H2
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n/an/an/a 3.24n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in SK-N-MC cells assessed as inhibition of forskolin-stimulated cAMP accumulation treate...


Eur J Med Chem 44: 4098-106 (2009)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50409817
PNG
(CHEMBL78498 | VUF-5681)
Show SMILES C(CC1CCNCC1)Cc1cnc[nH]1
Show InChI InChI=1S/C11H19N3/c1(3-11-8-13-9-14-11)2-10-4-6-12-7-5-10/h8-10,12H,1-7H2,(H,13,14)
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n/an/an/a 7.94n/an/an/an/an/a



Vrije Universiteit Amsterdam

Curated by ChEMBL


Assay Description
Inhibition of the cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing the human Histamine H3 receptor


J Med Chem 47: 2414-7 (2004)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50409729
PNG
(CHEMBL126904)
Show SMILES C(CN1CCCCC1)Oc1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C19H30N2O/c1-3-11-20(12-4-1)15-16-22-19-9-7-18(8-10-19)17-21-13-5-2-6-14-21/h7-10H,1-6,11-17H2
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n/an/an/a 8.91n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor


J Med Chem 46: 3938-44 (2003)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50409728
PNG
(CHEMBL337942)
Show SMILES CN(C)CCOc1ccc(CN2CCCCC2)cc1
Show InChI InChI=1S/C16H26N2O/c1-17(2)12-13-19-16-8-6-15(7-9-16)14-18-10-4-3-5-11-18/h6-9H,3-5,10-14H2,1-2H3
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n/an/an/a 10.5n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL


Assay Description
Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptor


J Med Chem 46: 3938-44 (2003)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM50327231
PNG
(4-(1-(3-(piperidin-1-yl)propyl)-3-(3-(piperidin-1-...)
Show SMILES C(CSc1nc(-c2ccncc2)n(CCCN2CCCCC2)n1)CN1CCCCC1
Show InChI InChI=1S/C23H36N6S/c1-3-13-27(14-4-1)17-7-19-29-22(21-9-11-24-12-10-21)25-23(26-29)30-20-8-18-28-15-5-2-6-16-28/h9-12H,1-8,13-20H2
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n/an/an/a 18n/an/an/an/an/a



Johann Wolfgang Goethe University

Curated by ChEMBL


Assay Description
Displacement of [3H]Methylhistamine from human histamine H3 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 20: 5883-6 (2010)

More data for this
Ligand-Target Pair
Histamine receptor (H3)


(Homo sapiens (human))
BDBM22914
PNG
(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1
Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)
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n/an/an/a 43.6n/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Mean functional activity against human H3 receptor


J Med Chem 48: 2229-38 (2005)

More data for this
Ligand-Target Pair