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Compile Data Set for Download or QSAR

Found 167 hits for UniProtKB: P03406   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tryrosine-Protein Kinase (HCK) + Protein Nef (NEF)


(Homo sapiens (Human)-Human immunodeficiency virus ...)
BDBM36545
PNG
(DFP-4APF | diphenylfuropyrimidine-4-aminopropylfur...)
Show SMILES C(CNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)Cc1ccco1
Show InChI InChI=1S/C25H21N3O2/c1-3-9-18(10-4-1)21-22-24(26-15-7-13-20-14-8-16-29-20)27-17-28-25(22)30-23(21)19-11-5-2-6-12-19/h1-6,8-12,14,16-17H,7,13,15H2,(H,26,27,28)
PDB

UniProtKB/SwissProt

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PC sid
UniChem

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Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/a25



University of Pittsburgh School of Medicine



Assay Description
In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.


ACS Chem Biol 4: 939-47 (2009)

More data for this
Ligand-Target Pair
Tryrosine-Protein Kinase (HCK) + Protein Nef (NEF)


(Homo sapiens (Human)-Human immunodeficiency virus ...)
BDBM14807
PNG
(3-(5,6-Diphenyl-furo[2,3-d]pyrimidin-4-ylamino)-pr...)
Show SMILES OCCCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Show InChI InChI=1S/C21H19N3O2/c25-13-7-12-22-20-18-17(15-8-3-1-4-9-15)19(16-10-5-2-6-11-16)26-21(18)24-14-23-20/h1-6,8-11,14,25H,7,12-13H2,(H,22,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
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PC sid
UniChem

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Article
PubMed
n/an/a 5.10E+3n/an/an/an/an/a25



University of Pittsburgh School of Medicine



Assay Description
In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.


ACS Chem Biol 4: 939-47 (2009)

More data for this
Ligand-Target Pair
Tryrosine-Protein Kinase (HCK) + Protein Nef (NEF)


(Homo sapiens (Human)-Human immunodeficiency virus ...)
BDBM36544
PNG
(DFP-4AB | Diphenylfuropyrimidine-4-aminobutanol)
Show SMILES OCCCCNc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Show InChI InChI=1S/C22H21N3O2/c26-14-8-7-13-23-21-19-18(16-9-3-1-4-10-16)20(17-11-5-2-6-12-17)27-22(19)25-15-24-21/h1-6,9-12,15,26H,7-8,13-14H2,(H,23,24,25)
PDB

UniProtKB/SwissProt

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antibodypedia
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PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/a25



University of Pittsburgh School of Medicine



Assay Description
In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.


ACS Chem Biol 4: 939-47 (2009)

More data for this
Ligand-Target Pair
Tryrosine-Protein Kinase (HCK) + Protein Nef (NEF)


(Homo sapiens (Human)-Human immunodeficiency virus ...)
BDBM14806
PNG
(5,6-Diphenyl-furo[2,3-d]pyrimidin-4 -ylamine | 5,6...)
Show SMILES Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1
Show InChI InChI=1S/C18H13N3O/c19-17-15-14(12-7-3-1-4-8-12)16(13-9-5-2-6-10-13)22-18(15)21-11-20-17/h1-11H,(H2,19,20,21)
PDB

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PubMed
n/an/a>3.00E+4n/an/an/an/an/a25



University of Pittsburgh School of Medicine



Assay Description
In vitro kinase activity of Nef-Hck complex and Hck alone using Z'-lyte kinase assay system and Tyr2 peptide substrate from Invitrogen.


ACS Chem Biol 4: 939-47 (2009)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288019
PNG
(US10087178, Example 1)
Show SMILES CO[C@H]1C[C@@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F
PDB
MMDB

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UniChem
Article
n/an/an/an/a 3.10n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288020
PNG
(US10087178, Example 2)
Show SMILES CO[C@H]1C[C@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F
PDB
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UniChem
Article
n/an/an/an/a 4.20n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288021
PNG
(US10087178, Example 3)
Show SMILES COCC1C[C@@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F
PDB
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UniChem
Article
n/an/an/an/a 3.20n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288022
PNG
(US10087178, Example 4)
Show SMILES COC[C@H]1C[C@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1cccc(Cl)c1F
PDB
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UniChem
Article
n/an/an/an/a 2.90n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288023
PNG
(US10087178, Example 5)
Show SMILES CCN1C(=O)c2c(O)c(=O)c(cn2C[C@]11CC(C1)OC)C(=O)NCc1cccc(Cl)c1F
PDB
MMDB

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UniChem
Article
n/an/an/an/a 2.90n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288024
PNG
(US10087178, Example 6)
Show SMILES CCN1C(=O)c2c(O)c(=O)c(cn2C[C@]11C[C@@H](C1)OC)C(=O)NCc1cccc(Cl)c1F
PDB
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Article
n/an/an/an/a 2n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288025
PNG
(US10087178, Example 7)
Show SMILES COC[C@H]1C[C@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(OC)c(Cl)c1F
PDB
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Article
n/an/an/an/a 5n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288027
PNG
(US10087178, Example 8)
Show SMILES COCC1C[C@@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(OC)c(Cl)c1F
PDB
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Article
n/an/an/an/a 8.10n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288028
PNG
(US10087178, Example 9)
Show SMILES CC(C)N1C[C@@]2(C[C@@H]2CO)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 5.60n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288029
PNG
(US10087178, Example 10)
Show SMILES COC[C@H]1C[C@@]11CN(C(C)C)C(=O)c2c(O)c(=O)c(cn12)C(=O)NCc1ccc(F)cc1F
PDB
MMDB

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UniChem
Article
n/an/an/an/a 3.60n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288030
PNG
(US10087178, Example 11 | US10087178, Example 15)
Show SMILES CC(C)N1C[C@@]2(C[C@H]2CO)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
MMDB

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Article
n/an/an/an/a 5.80n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288031
PNG
(US10087178, Example 12 | US10087178, Example 16)
Show SMILES COC[C@@H]1C[C@@]11CN(C(C)C)C(=O)c2c(O)c(=O)c(cn12)C(=O)NCc1ccc(F)cc1F
PDB
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Article
n/an/an/an/a 5n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288032
PNG
(US10087178, Example 13)
Show SMILES CC(C)N1C[C@]2(C[C@@H]2CO)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 5.40n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288033
PNG
(US10087178, Example 14)
Show SMILES COC[C@H]1C[C@]11CN(C(C)C)C(=O)c2c(O)c(=O)c(cn12)C(=O)NCc1ccc(F)cc1F
PDB
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Article
n/an/an/an/a 9.10n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288030
PNG
(US10087178, Example 11 | US10087178, Example 15)
Show SMILES CC(C)N1C[C@@]2(C[C@H]2CO)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 7.20n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288031
PNG
(US10087178, Example 12 | US10087178, Example 16)
Show SMILES COC[C@@H]1C[C@@]11CN(C(C)C)C(=O)c2c(O)c(=O)c(cn12)C(=O)NCc1ccc(F)cc1F
PDB
MMDB

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Article
n/an/an/an/a 6.10n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288036
PNG
(US10087178, Example 17)
Show SMILES CCN1C(=O)c2c(O)c(=O)c(cn2C[C@@]11C[C@@H]1COC)C(=O)NCc1cccc(Cl)c1F
PDB
MMDB

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Article
n/an/an/an/a 3.40n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288037
PNG
(US10087178, Example 18)
Show SMILES CCN1C(=O)c2c(O)c(=O)c(cn2C[C@]11C[C@H]1COC)C(=O)NCc1cccc(Cl)c1F
PDB
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Article
n/an/an/an/a 2.60n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288038
PNG
(US10087178, Example 19)
Show SMILES CC(C)N1C[C@@]2(C[C@@H]2C(=O)N(C)C)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 4.20n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288039
PNG
(US10087178, Example 20)
Show SMILES CC(C)N1CC2(CC(C2)N(C)C(C)=O)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
MMDB

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Article
n/an/an/an/a 20n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288040
PNG
(US10087178, Example 21)
Show SMILES CC(C)N1C[C@]2(C[C@H]2CS(C)(=O)=O)n2cc(C(=O)NCc3cccc(Cl)c3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 48n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288041
PNG
(US10087178, Example S1 | trans-3-(benzyloxy)-N-(2,...)
Show SMILES CC(C)N1C[C@@]2(C[C@@H](C2)OCc2ccccc2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 7.70n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288042
PNG
(US10087178, Example S2 | cis-3-(benzyloxy)-N-(2,4-...)
Show SMILES CC(C)N1C[C@]2(C[C@@H](C2)OCc2ccccc2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 10n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288043
PNG
(N-(2,4-difluorobenzyl)- trans-3,9'-dihydroxy-2'- i...)
Show SMILES CC(C)N1C[C@@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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n/an/an/an/a 11n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288044
PNG
(N-(2,4-difluorobenzyl)-cis- 3,9'-dihydroxy-2'-isop...)
Show SMILES CC(C)N1C[C@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Article
n/an/an/an/a 4.90n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288045
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Show SMILES CO[C@H]1C[C@]2(C1)CN(C(C)C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
PDB
MMDB

UniProtKB/SwissProt

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UniChem
Article
n/an/an/an/a 4.40n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288046
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-ci...)
Show SMILES CO[C@H]1C[C@@]2(C1)CN(C(C)C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
PDB
MMDB

UniProtKB/SwissProt

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UniChem
Article
n/an/an/an/a 3.70n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288047
PNG
(N-(2,4-difluorobenzyl)- trans-3-ethoxy-9'-hydroxy-...)
Show SMILES CCO[C@H]1C[C@]2(C1)CN(C(C)C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
PDB
MMDB

UniProtKB/SwissProt

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UniChem
Article
n/an/an/an/a 3.70n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288048
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Show SMILES COCCO[C@H]1C[C@]2(C1)CN(C(C)C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
PDB
MMDB

UniProtKB/SwissProt

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Article
n/an/an/an/a 5.30n/an/an/a25



Gilead Sciences Inc.





Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288049
PNG
(US10087178, Example S9 | trans-3-(benzyloxy)-N-(2,...)
Show SMILES CN1C[C@@]2(C[C@@H](C2)OCc2ccccc2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
PDB
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288050
PNG
(US10087178, Example S10 | cis-3-(benzyloxy)-N-(2,4...)
Show SMILES CN1C[C@]2(C[C@@H](C2)OCc2ccccc2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288051
PNG
(N-(2,4-difluorobenzyl)- trans-3,9'-dihydroxy-2'- m...)
Show SMILES CN1C[C@@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288052
PNG
(N-(2,4-difluorobenzyl)-cis- 3,9'-dihydroxy-2'-meth...)
Show SMILES CN1C[C@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288053
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-trans-3-methoxy...)
Show SMILES CO[C@H]1C[C@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288054
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-cis-3-methoxy-2...)
Show SMILES CO[C@H]1C[C@@]2(C1)CN(C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288055
PNG
(US10087178, Example S15 | trans-3-(benzyloxy)-N-(2...)
Show SMILES CCN1C[C@@]2(C[C@@H](C2)OCc2ccccc2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288056
PNG
(US10087178, Example S16 | cis-3-(benzyloxy)-N-(2,4...)
Show SMILES CCN1C[C@]2(C[C@@H](C2)OCc2ccccc2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288057
PNG
(N-(2,4-difluorobenzyl)-2'- ethyl-trans-3,9'-dihydr...)
Show SMILES CCN1C[C@@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288058
PNG
(N-(2,4-difluorobenzyl)-2'- ethyl-cis-3,9'-dihydrox...)
Show SMILES CCN1C[C@]2(C[C@H](O)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288059
PNG
(N-(2,4-difluorobenzyl)-2'- ethyl-9'-hydroxy-trans-...)
Show SMILES CCN1C[C@@]2(C[C@@H](C2)OC)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288060
PNG
(N-(2,4-difluorobenzyl)-2'- ethyl-9'-hydroxy-cis-3-...)
Show SMILES CCN1C[C@]2(C[C@@H](C2)OC)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288061
PNG
(N-(2,4-difluorobenzyl)-cis- 3-ethoxy-2'-ethyl-9'- ...)
Show SMILES CCO[C@H]1C[C@@]2(C1)CN(CC)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288062
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-cis-3- (hydroxy...)
Show SMILES CC(C)N1C[C@]2(C[C@H](CO)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288063
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-ci...)
Show SMILES COC[C@H]1C[C@@]2(C1)CN(C(C)C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288064
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-trans-3- (hydro...)
Show SMILES CC(C)N1C[C@@]2(C[C@H](CO)C2)n2cc(C(=O)NCc3ccc(F)cc3F)c(=O)c(O)c2C1=O
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
HIV-1 Nef


(Human immunodeficiency virus type 1 (isolate BRU/L...)
BDBM288065
PNG
(N-(2,4-difluorobenzyl)-9'- hydroxy-2'-isopropyl-tr...)
Show SMILES COC[C@H]1C[C@]2(C1)CN(C(C)C)C(=O)c1c(O)c(=O)c(cn21)C(=O)NCc1ccc(F)cc1F
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Bioorg Med Chem Lett 10: 1257-60 (2000)

More data for this
Ligand-Target Pair
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