Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA ligase (Bacteriophage T4) | BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | J Biol Chem 280: 30273-81 (2005) Article DOI: 10.1074/jbc.M503780200 BindingDB Entry DOI: 10.7270/Q2SX6BGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22982 (Glycosyl Ureides, 3b | ethyl 3-[(3aS,6R,6aS)-6-(be...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | J Biol Chem 280: 30273-81 (2005) Article DOI: 10.1074/jbc.M503780200 BindingDB Entry DOI: 10.7270/Q2SX6BGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22981 (Glycosyl Ureides, 3a | ethyl 3-[(3aS,6R,6aS)-6-(be...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | J Biol Chem 280: 30273-81 (2005) Article DOI: 10.1074/jbc.M503780200 BindingDB Entry DOI: 10.7270/Q2SX6BGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22984 ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University Curated by ChEMBL | Assay Description Inhibition of T4 ligase from bacteriophage infected Escherichia coli assessed as ligation of supercoiled pBR322 DNA | J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22986 (18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.04E+5 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | Proteins 69: 97-111 (2007) Article DOI: 10.1002/prot.21457 BindingDB Entry DOI: 10.7270/Q2P55KSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22983 (ethyl 3-[({3-[({1-[(3aR,6S,6aR)-6-(benzyloxy)-2,2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.39E+5 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | J Biol Chem 280: 30273-81 (2005) Article DOI: 10.1074/jbc.M503780200 BindingDB Entry DOI: 10.7270/Q2SX6BGR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM50242374 (CHEMBL505529 | topostatin) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University Curated by ChEMBL | Assay Description Inhibition of T4 ligase from bacteriophage infected Escherichia coli assessed as ligation of supercoiled pBR322 DNA | J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM50008923 ((S)-4-ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University Curated by ChEMBL | Assay Description Inhibition of T4 ligase from bacteriophage infected Escherichia coli assessed as ligation of supercoiled pBR322 DNA | J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM50164888 (6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University Curated by ChEMBL | Assay Description Inhibition of T4 ligase from bacteriophage infected Escherichia coli assessed as ligation of supercoiled pBR322 DNA | J Nat Prod 64: 204-7 (2001) BindingDB Entry DOI: 10.7270/Q2W37W21 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22985 (Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+6 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | Proteins 69: 97-111 (2007) Article DOI: 10.1002/prot.21457 BindingDB Entry DOI: 10.7270/Q2P55KSS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA ligase (Bacteriophage T4) | BDBM22985 (Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+6 | n/a | n/a | n/a | n/a | 7.6 | 25 |
India Central Drug Research Institute | Assay Description The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were... | J Biol Chem 280: 30273-81 (2005) Article DOI: 10.1074/jbc.M503780200 BindingDB Entry DOI: 10.7270/Q2SX6BGR | |||||||||||
More data for this Ligand-Target Pair |