Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23215 (Homoisocitrate thia analogue, 3 | trisodium (2S,3S...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 97 | -9.91 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 16: 3372-6 (2008) Article DOI: 10.1016/j.bmc.2007.12.002 BindingDB Entry DOI: 10.7270/Q2RX99D8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23213 (Homoisocitrate oxa analogue, 2 | trisodium (2S,3R)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | Article PubMed | 1.00E+4 | -7.07 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 16: 3372-6 (2008) Article DOI: 10.1016/j.bmc.2007.12.002 BindingDB Entry DOI: 10.7270/Q2RX99D8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23216 (3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid | ...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 1.20E+4 | -6.96 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 16: 3372-6 (2008) Article DOI: 10.1016/j.bmc.2007.12.002 BindingDB Entry DOI: 10.7270/Q2RX99D8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23220 ((1R,2Z)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 7.20E+4 | -5.86 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 15: 1346-55 (2007) Article DOI: 10.1016/j.bmc.2006.11.008 BindingDB Entry DOI: 10.7270/Q2N87824 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23218 ((2R,3Z)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 5.10E+5 | -4.65 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 15: 1346-55 (2007) Article DOI: 10.1016/j.bmc.2006.11.008 BindingDB Entry DOI: 10.7270/Q2N87824 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23219 ((1R,2E)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 7.90E+5 | -4.39 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 15: 1346-55 (2007) Article DOI: 10.1016/j.bmc.2006.11.008 BindingDB Entry DOI: 10.7270/Q2N87824 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Homoisocitrate dehydrogenase, mitochondrial (Saccharomyces cerevisiae) | BDBM23217 ((2R,3E)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.40E+6 | -4.03 | n/a | n/a | n/a | n/a | n/a | 7.8 | 36 |
Tokyo Institute of Technology | Assay Description Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ... | Bioorg Med Chem 15: 1346-55 (2007) Article DOI: 10.1016/j.bmc.2006.11.008 BindingDB Entry DOI: 10.7270/Q2N87824 | |||||||||||
More data for this Ligand-Target Pair |