Found 6 hits of kd data for polymerid = 2421 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Equilibrative nucleoside transporter 1
(Homo sapiens (Human)) | BDBM50301068
(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)Show SMILES O[C@@H]1[C@@H](CSCCNC(=O)CCCCCNC(=O)c2ccc3c(c2)C(=O)OC32C3=C(CC(=O)CC3)Oc3cc(O)ccc23)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccc(cc3)[N+]([O-])=O)ncnc12 |r,t:30| Show InChI InChI=1S/C46H46N8O12S/c55-28-10-13-32-34(19-28)64-35-20-29(56)11-14-33(35)46(32)31-12-7-26(18-30(31)45(61)66-46)43(60)48-15-3-1-2-4-37(57)47-16-17-67-22-36-39(58)40(59)44(65-36)53-24-52-38-41(50-23-51-42(38)53)49-21-25-5-8-27(9-6-25)54(62)63/h5-10,12-13,18-19,23-24,36,39-40,44,55,58-59H,1-4,11,14-17,20-22H2,(H,47,57)(H,48,60)(H,49,50,51)/t36-,39-,40-,44-,46?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.260 | n/a | n/a | n/a | n/a | n/a |
Ulm University
Curated by ChEMBL
| Assay Description
Binding affinity to human ENT1 in HL60 cells by flow cytometry |
Bioorg Med Chem Lett 19: 5151-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.017
BindingDB Entry DOI: 10.7270/Q2QJ7HCF |
More data for this
Ligand-Target Pair | |
Equilibrative nucleoside transporter 1
(Homo sapiens (Human)) | BDBM50301068
(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)Show SMILES O[C@@H]1[C@@H](CSCCNC(=O)CCCCCNC(=O)c2ccc3c(c2)C(=O)OC32C3=C(CC(=O)CC3)Oc3cc(O)ccc23)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccc(cc3)[N+]([O-])=O)ncnc12 |r,t:30| Show InChI InChI=1S/C46H46N8O12S/c55-28-10-13-32-34(19-28)64-35-20-29(56)11-14-33(35)46(32)31-12-7-26(18-30(31)45(61)66-46)43(60)48-15-3-1-2-4-37(57)47-16-17-67-22-36-39(58)40(59)44(65-36)53-24-52-38-41(50-23-51-42(38)53)49-21-25-5-8-27(9-6-25)54(62)63/h5-10,12-13,18-19,23-24,36,39-40,44,55,58-59H,1-4,11,14-17,20-22H2,(H,47,57)(H,48,60)(H,49,50,51)/t36-,39-,40-,44-,46?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a |
Ulm University
Curated by ChEMBL
| Assay Description
Binding affinity to human ENT1 in Capan1 cells by flow cytometry |
Bioorg Med Chem Lett 19: 5151-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.017
BindingDB Entry DOI: 10.7270/Q2QJ7HCF |
More data for this
Ligand-Target Pair | |
Equilibrative nucleoside transporter 1
(Homo sapiens (Human)) | BDBM50301068
(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)Show SMILES O[C@@H]1[C@@H](CSCCNC(=O)CCCCCNC(=O)c2ccc3c(c2)C(=O)OC32C3=C(CC(=O)CC3)Oc3cc(O)ccc23)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccc(cc3)[N+]([O-])=O)ncnc12 |r,t:30| Show InChI InChI=1S/C46H46N8O12S/c55-28-10-13-32-34(19-28)64-35-20-29(56)11-14-33(35)46(32)31-12-7-26(18-30(31)45(61)66-46)43(60)48-15-3-1-2-4-37(57)47-16-17-67-22-36-39(58)40(59)44(65-36)53-24-52-38-41(50-23-51-42(38)53)49-21-25-5-8-27(9-6-25)54(62)63/h5-10,12-13,18-19,23-24,36,39-40,44,55,58-59H,1-4,11,14-17,20-22H2,(H,47,57)(H,48,60)(H,49,50,51)/t36-,39-,40-,44-,46?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a |
Ulm University
Curated by ChEMBL
| Assay Description
Binding affinity to human ENT1 in BX-PC3 cells by flow cytometry |
Bioorg Med Chem Lett 19: 5151-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.017
BindingDB Entry DOI: 10.7270/Q2QJ7HCF |
More data for this
Ligand-Target Pair | |
Equilibrative nucleoside transporter 1
(Homo sapiens (Human)) | BDBM50301068
(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)Show SMILES O[C@@H]1[C@@H](CSCCNC(=O)CCCCCNC(=O)c2ccc3c(c2)C(=O)OC32C3=C(CC(=O)CC3)Oc3cc(O)ccc23)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccc(cc3)[N+]([O-])=O)ncnc12 |r,t:30| Show InChI InChI=1S/C46H46N8O12S/c55-28-10-13-32-34(19-28)64-35-20-29(56)11-14-33(35)46(32)31-12-7-26(18-30(31)45(61)66-46)43(60)48-15-3-1-2-4-37(57)47-16-17-67-22-36-39(58)40(59)44(65-36)53-24-52-38-41(50-23-51-42(38)53)49-21-25-5-8-27(9-6-25)54(62)63/h5-10,12-13,18-19,23-24,36,39-40,44,55,58-59H,1-4,11,14-17,20-22H2,(H,47,57)(H,48,60)(H,49,50,51)/t36-,39-,40-,44-,46?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
Ulm University
Curated by ChEMBL
| Assay Description
Binding affinity to human ENT1 in SK-PC1 cells by flow cytometry |
Bioorg Med Chem Lett 19: 5151-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.017
BindingDB Entry DOI: 10.7270/Q2QJ7HCF |
More data for this
Ligand-Target Pair | |
Equilibrative nucleoside transporter 1
(Homo sapiens (Human)) | BDBM50301068
(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)Show SMILES O[C@@H]1[C@@H](CSCCNC(=O)CCCCCNC(=O)c2ccc3c(c2)C(=O)OC32C3=C(CC(=O)CC3)Oc3cc(O)ccc23)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccc(cc3)[N+]([O-])=O)ncnc12 |r,t:30| Show InChI InChI=1S/C46H46N8O12S/c55-28-10-13-32-34(19-28)64-35-20-29(56)11-14-33(35)46(32)31-12-7-26(18-30(31)45(61)66-46)43(60)48-15-3-1-2-4-37(57)47-16-17-67-22-36-39(58)40(59)44(65-36)53-24-52-38-41(50-23-51-42(38)53)49-21-25-5-8-27(9-6-25)54(62)63/h5-10,12-13,18-19,23-24,36,39-40,44,55,58-59H,1-4,11,14-17,20-22H2,(H,47,57)(H,48,60)(H,49,50,51)/t36-,39-,40-,44-,46?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.910 | n/a | n/a | n/a | n/a | n/a |
Ulm University
Curated by ChEMBL
| Assay Description
Binding affinity to human ENT1 in MIA-PaCa2 cells by flow cytometry |
Bioorg Med Chem Lett 19: 5151-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.017
BindingDB Entry DOI: 10.7270/Q2QJ7HCF |
More data for this
Ligand-Target Pair | |
Equilibrative nucleoside transporter 1
(Homo sapiens (Human)) | BDBM50301068
(5'-[(fluorescein-5-ylcarbonyl)-6-aminohexanoyl-(2-...)Show SMILES O[C@@H]1[C@@H](CSCCNC(=O)CCCCCNC(=O)c2ccc3c(c2)C(=O)OC32C3=C(CC(=O)CC3)Oc3cc(O)ccc23)O[C@H]([C@@H]1O)n1cnc2c(NCc3ccc(cc3)[N+]([O-])=O)ncnc12 |r,t:30| Show InChI InChI=1S/C46H46N8O12S/c55-28-10-13-32-34(19-28)64-35-20-29(56)11-14-33(35)46(32)31-12-7-26(18-30(31)45(61)66-46)43(60)48-15-3-1-2-4-37(57)47-16-17-67-22-36-39(58)40(59)44(65-36)53-24-52-38-41(50-23-51-42(38)53)49-21-25-5-8-27(9-6-25)54(62)63/h5-10,12-13,18-19,23-24,36,39-40,44,55,58-59H,1-4,11,14-17,20-22H2,(H,47,57)(H,48,60)(H,49,50,51)/t36-,39-,40-,44-,46?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a |
Ulm University
Curated by ChEMBL
| Assay Description
Binding affinity to human ENT1 in panc1 cells by flow cytometry |
Bioorg Med Chem Lett 19: 5151-4 (2009)
Article DOI: 10.1016/j.bmcl.2009.07.017
BindingDB Entry DOI: 10.7270/Q2QJ7HCF |
More data for this
Ligand-Target Pair | |
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