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Compile Data Set for Download or QSAR

Found 141 hits of ic50 for UniProtKB: P00592   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055367
PNG
(CHEMBL345986 | [3-Aminooxalyl-1-(3-chloro-benzyl)-...)
Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(Cl)c1
Show InChI InChI=1S/C21H19ClN2O5/c1-2-14-19(20(27)21(23)28)18-15(7-4-8-16(18)29-11-17(25)26)24(14)10-12-5-3-6-13(22)9-12/h3-9H,2,10-11H2,1H3,(H2,23,28)(H,25,26)
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n/an/a 3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound wastested for inhibition of porcine secreted pancreatic PLA2

J Med Chem 39: 5159-75 (1997)


Article DOI: 10.1021/jm960487f
BindingDB Entry DOI: 10.7270/Q22B8X54
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055384
PNG
((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C26H22N2O5/c1-16-23(25(31)26(27)32)24-20(11-6-12-21(24)33-15-22(29)30)28(16)14-17-7-5-10-19(13-17)18-8-3-2-4-9-18/h2-13H,14-15H2,1H3,(H2,27,32)(H,29,30)
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n/an/a 7n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01808
BindingDB Entry DOI: 10.7270/Q2SF316G
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055384
PNG
((3-Aminooxalyl-1-biphenyl-3-ylmethyl-2-methyl-1H-i...)
Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C26H22N2O5/c1-16-23(25(31)26(27)32)24-20(11-6-12-21(24)33-15-22(29)30)28(16)14-17-7-5-10-19(13-17)18-8-3-2-4-9-18/h2-13H,14-15H2,1H3,(H2,27,32)(H,29,30)
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n/an/a 7n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2

J Med Chem 39: 5159-75 (1997)


Article DOI: 10.1021/jm960487f
BindingDB Entry DOI: 10.7270/Q22B8X54
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055383
PNG
((3-Aminooxalyl-1-benzyl-2-methyl-1H-indol-4-yloxy)...)
Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1
Show InChI InChI=1S/C20H18N2O5/c1-12-17(19(25)20(21)26)18-14(8-5-9-15(18)27-11-16(23)24)22(12)10-13-6-3-2-4-7-13/h2-9H,10-11H2,1H3,(H2,21,26)(H,23,24)
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n/an/a 15n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01808
BindingDB Entry DOI: 10.7270/Q2SF316G
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055383
PNG
((3-Aminooxalyl-1-benzyl-2-methyl-1H-indol-4-yloxy)...)
Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1
Show InChI InChI=1S/C20H18N2O5/c1-12-17(19(25)20(21)26)18-14(8-5-9-15(18)27-11-16(23)24)22(12)10-13-6-3-2-4-7-13/h2-9H,10-11H2,1H3,(H2,21,26)(H,23,24)
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n/an/a 15n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2

J Med Chem 39: 5159-75 (1997)


Article DOI: 10.1021/jm960487f
BindingDB Entry DOI: 10.7270/Q22B8X54
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004495
PNG
(CHEMBL101015 | Hexadecanoic acid 3-[hydroxy-(2-hyd...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCCO)NC(=O)CCCCCCCCCCCCC
Show InChI InChI=1S/C35H70NO8P/c1-3-5-7-9-11-13-15-16-18-20-22-24-26-28-35(39)42-31-33(32-44-45(40,41)43-30-29-37)36-34(38)27-25-23-21-19-17-14-12-10-8-6-4-2/h33,37H,3-32H2,1-2H3,(H,36,38)(H,40,41)
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n/an/a 30n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004502
PNG
(CHEMBL101972 | Phosphoric acid 2-hexadecanoylamino...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(=O)OCCO)CC(C)C
Show InChI InChI=1S/C24H50NO6P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(27)25-23(20-22(2)3)21-31-32(28,29)30-19-18-26/h22-23,26H,4-21H2,1-3H3,(H,25,27)(H,28,29)/t23-/m1/s1
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Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055366
PNG
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1
Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
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n/an/a 48n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of porcine secretory pancreatic PLA2

J Med Chem 39: 5159-75 (1997)


Article DOI: 10.1021/jm960487f
BindingDB Entry DOI: 10.7270/Q22B8X54
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055366
PNG
((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Show SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1
Show InChI InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
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n/an/a 48n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01808
BindingDB Entry DOI: 10.7270/Q2SF316G
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055371
PNG
((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1-c1ccccc1
Show InChI InChI=1S/C26H22N2O5/c1-16-23(25(31)26(27)32)24-20(12-7-13-21(24)33-15-22(29)30)28(16)14-18-10-5-6-11-19(18)17-8-3-2-4-9-17/h2-13H,14-15H2,1H3,(H2,27,32)(H,29,30)
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n/an/a 97n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2

J Med Chem 39: 5159-75 (1997)


Article DOI: 10.1021/jm960487f
BindingDB Entry DOI: 10.7270/Q22B8X54
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055371
PNG
((3-aminooxalyl-1-biphenyl-2-ylmethyl-2-methyl-1H-i...)
Show SMILES Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1-c1ccccc1
Show InChI InChI=1S/C26H22N2O5/c1-16-23(25(31)26(27)32)24-20(12-7-13-21(24)33-15-22(29)30)28(16)14-18-10-5-6-11-19(18)17-8-3-2-4-9-17/h2-13H,14-15H2,1H3,(H2,27,32)(H,29,30)
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n/an/a 97n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c01808
BindingDB Entry DOI: 10.7270/Q2SF316G
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004499
PNG
((R)-O-(2-Hexadecanamidoisohexyl) phosphocholine | ...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)CC(C)C
Show InChI InChI=1S/C27H57N2O5P/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-27(30)28-26(23-25(2)3)24-34-35(31,32)33-22-21-29(4,5)6/h25-26H,7-24H2,1-6H3,(H-,28,30,31,32)/t26-/m1/s1
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n/an/a 230n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50269843
PNG
(Bolinaquinone | CHEMBL477692)
Show SMILES COC1=CC(=O)C(=O)C(C[C@@]2(C)CC[C@@]3(C)[C@@H](CCC=C3C)[C@H]2C)C1=O |r,c:19,t:2|
Show InChI InChI=1S/C22H30O4/c1-13-7-6-8-16-14(2)21(3,9-10-22(13,16)4)12-15-19(24)17(23)11-18(26-5)20(15)25/h7,11,14-16H,6,8-10,12H2,1-5H3/t14-,15?,16+,21-,22-/m1/s1
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n/an/a 400n/an/an/an/an/an/a



Università degli Studi di Napoli Federico II

Curated by ChEMBL


Assay Description
Inhibition of pig pancreatic group 1 secretory phospholipase A2 by liquid scintillation counting

J Nat Prod 64: 612-5 (2001)


BindingDB Entry DOI: 10.7270/Q28915MQ
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055287
PNG
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1
Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27)
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n/an/a 610n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for the inhibitory activity against porcine pancreatic PLA2

J Med Chem 39: 5137-58 (1997)


Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50031087
PNG
(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1[nH]c(SC#N)cc1-c1ccc(F)cc1
Show InChI InChI=1S/C18H13FN2O2S2/c1-25(22,23)15-8-4-13(5-9-15)18-16(10-17(21-18)24-11-20)12-2-6-14(19)7-3-12/h2-10,21H,1H3
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n/an/a 1.10E+3n/an/an/an/an/an/a



Du Pont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibitory activity rat polymorphonuclear leukocyte phospholipase-A2 (PMN-PLA2)

J Med Chem 37: 988-98 (1994)


BindingDB Entry DOI: 10.7270/Q2BP01WP
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004504
PNG
((R)-O-(2-Hexadecanamidopropyl] phosphocholine | CH...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@H](C)COP([O-])(=O)OCC[N+](C)(C)C
Show InChI InChI=1S/C24H51N2O5P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24(27)25-23(2)22-31-32(28,29)30-21-20-26(3,4)5/h23H,6-22H2,1-5H3,(H-,25,27,28,29)/t23-/m1/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50206912
PNG
((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Show SMILES CCCCCCCCCCCCCCOC(COCCCCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1
Show InChI InChI=1S/C35H52N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-17-27-40-33(28-39-26-18-16-21-30-19-14-13-15-20-30)29-41-32-24-22-31(23-25-32)34-36-35(38)42-37-34/h13-15,19-20,22-25,33H,2-12,16-18,21,26-29H2,1H3,(H,36,37,38)
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n/an/a 2.20E+3n/an/an/an/an/an/a



Université Paris7-Denis Diderot

Curated by ChEMBL


Assay Description
Inhibition of pig group IB PLA2 by fluorimetric assay

J Med Chem 50: 1618-26 (2007)


Article DOI: 10.1021/jm060082n
BindingDB Entry DOI: 10.7270/Q2TQ6174
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004502
PNG
(CHEMBL101972 | Phosphoric acid 2-hexadecanoylamino...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(=O)OCCO)CC(C)C
Show InChI InChI=1S/C24H50NO6P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-24(27)25-23(20-22(2)3)21-31-32(28,29)30-19-18-26/h22-23,26H,4-21H2,1-3H3,(H,25,27)(H,28,29)/t23-/m1/s1
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n/an/a 2.60E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004495
PNG
(CHEMBL101015 | Hexadecanoic acid 3-[hydroxy-(2-hyd...)
Show SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCCO)NC(=O)CCCCCCCCCCCCC
Show InChI InChI=1S/C35H70NO8P/c1-3-5-7-9-11-13-15-16-18-20-22-24-26-28-35(39)42-31-33(32-44-45(40,41)43-30-29-37)36-34(38)27-25-23-21-19-17-14-12-10-8-6-4-2/h33,37H,3-32H2,1-2H3,(H,36,38)(H,40,41)
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n/an/a 3.50E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316463
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)N1CCN(CC1)C(=O)Nc1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C33H54N6O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-34-31(40)38-23-25-39(26-24-38)32(41)35-29-20-18-28(19-21-29)27-30-36-33(42)43-37-30/h18-21H,2-17,22-27H2,1H3,(H,34,40)(H,35,41)(H,36,37,42)
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n/an/a 3.58E+3n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50055287
PNG
(4-(1-Benzyl-3-carbamoylmethyl-2-methyl-1H-indol-4-...)
Show SMILES Cc1c(CC(N)=O)c2c(OCCCC(O)=O)cccc2n1Cc1ccccc1
Show InChI InChI=1S/C22H24N2O4/c1-15-17(13-20(23)25)22-18(24(15)14-16-7-3-2-4-8-16)9-5-10-19(22)28-12-6-11-21(26)27/h2-5,7-10H,6,11-14H2,1H3,(H2,23,25)(H,26,27)
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n/an/a 3.66E+3n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Compound was tested for the inhibitory activity against human pancreatic PLA2

J Med Chem 39: 5137-58 (1997)


Article DOI: 10.1021/jm960486n
BindingDB Entry DOI: 10.7270/Q2639NV0
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004493
PNG
(CHEMBL101890 | O-(2-hexadecanamidoethyl) phosphoch...)
Show SMILES CCCCCCCCCCCCCCCC(=O)NCCOP([O-])(=O)OCC[N+](C)(C)C
Show InChI InChI=1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)24-19-21-29-31(27,28)30-22-20-25(2,3)4/h5-22H2,1-4H3,(H-,24,26,27,28)
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n/an/a 4.00E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004505
PNG
((S)-O-(2-Hexadecanamidoisohexyl) phosphocholine | ...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@H](COP([O-])(=O)OCC[N+](C)(C)C)CC(C)C
Show InChI InChI=1S/C27H57N2O5P/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-27(30)28-26(23-25(2)3)24-34-35(31,32)33-22-21-29(4,5)6/h25-26H,7-24H2,1-6H3,(H-,28,30,31,32)/t26-/m0/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004500
PNG
(CHEMBL319067 | Phosphoric acid mono-(2-hexadecanoy...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccccc1
Show InChI InChI=1S/C25H44NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-25(27)26-24(22-31-32(28,29)30)21-23-18-15-14-16-19-23/h14-16,18-19,24H,2-13,17,20-22H2,1H3,(H,26,27)(H2,28,29,30)/t24-/m1/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316459
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCOc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C34H48N4O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-26-41-31-20-18-30(19-21-31)37-22-24-38(25-23-37)33(39)29-16-14-28(15-17-29)27-32-35-34(40)42-36-32/h14-21H,2-13,22-27H2,1H3,(H,35,36,40)
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n/an/a 5.33E+3n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50280987
PNG
(1N-[12-isopropyl-2,6-dimethyltricyclo[8.4.0.02,7]t...)
Show SMILES CC(N)CCCNC[C@]1(C)CCC[C@@]2(C)C1CCc1cc(ccc21)C(C)C |r|
Show InChI InChI=1S/C25H42N2/c1-18(2)20-9-11-22-21(16-20)10-12-23-24(4,13-7-14-25(22,23)5)17-27-15-6-8-19(3)26/h9,11,16,18-19,23,27H,6-8,10,12-15,17,26H2,1-5H3/t19?,23?,24-,25+/m0/s1
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n/an/a 5.40E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for its inhibitory activity against Phospholipase A2 (PLA2)

Bioorg Med Chem Lett 3: 2087-2092 (1993)


Article DOI: 10.1016/S0960-894X(01)81022-2
BindingDB Entry DOI: 10.7270/Q2G73F6K
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50206913
PNG
((+/-)-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4H-oxadiazol...)
Show SMILES CCCCCCCCCCCCCCOC(COC(c1ccccc1)c1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1
Show InChI InChI=1S/C38H50N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-19-28-42-35(29-43-34-26-24-33(25-27-34)37-39-38(41)45-40-37)30-44-36(31-20-15-13-16-21-31)32-22-17-14-18-23-32/h13-18,20-27,35-36H,2-12,19,28-30H2,1H3,(H,39,40,41)
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n/an/a 5.60E+3n/an/an/an/an/an/a



Université Paris7-Denis Diderot

Curated by ChEMBL


Assay Description
Inhibition of pig group IB PLA2 by fluorimetric assay

J Med Chem 50: 1618-26 (2007)


Article DOI: 10.1021/jm060082n
BindingDB Entry DOI: 10.7270/Q2TQ6174
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004501
PNG
((E)-(R)-O-(2-Dec-3-enamidoisohexyl) phosphocholine...)
Show SMILES CCCCC\C=C/CCC(=O)N[C@@H](COP([O-])(=O)OCC[N+](C)(C)C)CC(C)C
Show InChI InChI=1S/C21H43N2O5P/c1-7-8-9-10-11-12-13-14-21(24)22-20(17-19(2)3)18-28-29(25,26)27-16-15-23(4,5)6/h11-12,19-20H,7-10,13-18H2,1-6H3,(H-,22,24,25,26)/b12-11-/t20-/m1/s1
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n/an/a 6.00E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316458
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCCCCCOc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C38H56N4O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30-45-35-24-22-34(23-25-35)41-26-28-42(29-27-41)37(43)33-20-18-32(19-21-33)31-36-39-38(44)46-40-36/h18-25H,2-17,26-31H2,1H3,(H,39,40,44)
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n/an/a 7.40E+3n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316456
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCCCCCOc1ccc(cc1)N1CCN(Cc2ccc(Cc3nc(=O)o[nH]3)cc2)CC1
Show InChI InChI=1S/C38H58N4O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30-44-36-24-22-35(23-25-36)42-28-26-41(27-29-42)32-34-20-18-33(19-21-34)31-37-39-38(43)45-40-37/h18-25H,2-17,26-32H2,1H3,(H,39,40,43)
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n/an/a 7.41E+3n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM23771
PNG
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1
Show InChI InChI=1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Universite Paris 7-Denis Diderot



Assay Description
PLA2 activity is by using the fluorescent phospholipid analogue as the substrate. The increase in fluorescence (ex @342 nm and em@388 nm) of the enzy...

Bioorg Med Chem 16: 1242-53 (2008)


Article DOI: 10.1016/j.bmc.2007.10.077
BindingDB Entry DOI: 10.7270/Q2J964PK
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004498
PNG
(CHEMBL99161 | O-[2-(2-Naphthalenecarboxamido)ethyl...)
Show SMILES C[N+](C)(C)CCOP([O-])(=O)OCCNC(=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C18H25N2O5P/c1-20(2,3)11-13-25-26(22,23)24-12-10-19-18(21)17-9-8-15-6-4-5-7-16(15)14-17/h4-9,14H,10-13H2,1-3H3,(H-,19,21,22,23)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM23771
PNG
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1
Show InChI InChI=1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Université Paris7-Denis Diderot

Curated by ChEMBL


Assay Description
Inhibition of pig group IB PLA2 by fluorimetric assay

J Med Chem 50: 1618-26 (2007)


Article DOI: 10.1021/jm060082n
BindingDB Entry DOI: 10.7270/Q2TQ6174
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM23771
PNG
((3-{[1-benzyl-3-(carbamoylmethyl)-2-ethyl-1H-indol...)
Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)ccc2n1Cc1ccccc1
Show InChI InChI=1S/C22H27N2O5P/c1-2-20-19(14-22(23)25)18-13-17(29-11-6-12-30(26,27)28)9-10-21(18)24(20)15-16-7-4-3-5-8-16/h3-5,7-10,13H,2,6,11-12,14-15H2,1H3,(H2,23,25)(H2,26,27,28)
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n/an/a 8.00E+3n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50206908
PNG
((+/-)-1-O-(4-cyanomethylphenyl)-3-O-[4-(4,5-dihydr...)
Show SMILES CCCCCCCCCCCCCCOC(COCc1ccc(cc1)C#N)COc1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C34H47N3O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-22-40-32(26-39-25-30-16-14-29(24-35)15-17-30)27-41-31-20-18-28(19-21-31)23-33-36-34(38)42-37-33/h14-21,32H,2-13,22-23,25-27H2,1H3,(H,36,37,38)
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n/an/a 9.60E+3n/an/an/an/an/an/a



Université Paris7-Denis Diderot

Curated by ChEMBL


Assay Description
Inhibition of pig group IB PLA2 by fluorimetric assay

J Med Chem 50: 1618-26 (2007)


Article DOI: 10.1021/jm060082n
BindingDB Entry DOI: 10.7270/Q2TQ6174
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004496
PNG
(CHEMBL318193 | Phosphoric acid mono-(2-hexadecanoy...)
Show SMILES CCCCCCCCCCCCCCCC(=O)N[C@@H](COP(O)(O)=O)CC(C)C
Show InChI InChI=1S/C22H46NO5P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(24)23-21(18-20(2)3)19-28-29(25,26)27/h20-21H,4-19H2,1-3H3,(H,23,24)(H2,25,26,27)/t21-/m1/s1
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n/an/a 1.00E+4n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by monomeric substrate assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316457
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCOc1ccc(cc1)N1CCN(Cc2ccc(Cc3nc(=O)o[nH]3)cc2)CC1
Show InChI InChI=1S/C34H50N4O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-26-40-32-20-18-31(19-21-32)38-24-22-37(23-25-38)28-30-16-14-29(15-17-30)27-33-35-34(39)41-36-33/h14-21H,2-13,22-28H2,1H3,(H,35,36,39)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50591711
PNG
(CHEMBL5203236)
Show SMILES O=c1[nH]c2ccccc2nc1N\N=C\c1cccs1
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n/an/a 1.07E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50591712
PNG
(CHEMBL5194852)
Show SMILES COc1cccc(\C=N\Nc2nc3ccccc3[nH]c2=O)c1
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n/an/a 1.24E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50591713
PNG
(CHEMBL5207115)
Show SMILES [O-][N+](=O)c1ccc(-c2ccc3n2c2ccccc2[nH]c3=O)c(c1)[N+]([O-])=O
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n/an/a 1.36E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50591715
PNG
(CHEMBL5179709)
Show SMILES Clc1ccc(cc1Cl)-c1ccc2n1c1ccccc1[nH]c2=O
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n/an/a 1.45E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50591714
PNG
(CHEMBL5200953)
Show SMILES Oc1ccc(-c2ccc3n2c2ccccc2[nH]c3=O)c(O)c1
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n/an/a 1.48E+4n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2021.114085
BindingDB Entry DOI: 10.7270/Q2XW4PS2
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50004497
PNG
(CHEMBL330205 | Phosphoric acid 2-trimethylamino-et...)
Show SMILES CCCCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)NC(=O)CCCCCCCCCCCCCCC
Show InChI InChI=1S/C42H87N2O6P/c1-6-8-10-12-14-16-18-20-21-22-24-26-28-30-32-34-37-48-39-41(40-50-51(46,47)49-38-36-44(3,4)5)43-42(45)35-33-31-29-27-25-23-19-17-15-13-11-9-7-2/h41H,6-40H2,1-5H3,(H-,43,45,46,47)/t41-/m1/s1
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n/an/a 1.50E+4n/an/an/an/an/an/a



Fisons plc

Curated by ChEMBL


Assay Description
In vitro inhibition of porcine pancreatic phospholipase A2 evaluated by Deoxycholate-phospholipid mixed micelle assay

J Med Chem 35: 2939-51 (1992)


BindingDB Entry DOI: 10.7270/Q2RF5T0R
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50280984
PNG
(C-((4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a...)
Show SMILES CC(C)c1ccc2c(CC[C@H]3C(C)(CN)CCC[C@]23C)c1 |r|
Show InChI InChI=1S/C20H31N/c1-14(2)15-6-8-17-16(12-15)7-9-18-19(3,13-21)10-5-11-20(17,18)4/h6,8,12,14,18H,5,7,9-11,13,21H2,1-4H3/t18-,19?,20+/m0/s1
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n/an/a 2.10E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested for its inhibitory activity against Phospholipase A2 (PLA2)

Bioorg Med Chem Lett 3: 2087-2092 (1993)


Article DOI: 10.1016/S0960-894X(01)81022-2
BindingDB Entry DOI: 10.7270/Q2G73F6K
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316460
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCOc1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C30H40N4O4/c1-2-3-4-5-6-7-8-9-22-37-27-16-14-26(15-17-27)33-18-20-34(21-19-33)29(35)25-12-10-24(11-13-25)23-28-31-30(36)38-32-28/h10-17H,2-9,18-23H2,1H3,(H,31,32,36)
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n/an/a 2.16E+4n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316454
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)N1CCN(CC1)C(=O)c1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C33H53N5O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-34-32(40)38-25-23-37(24-26-38)31(39)29-20-18-28(19-21-29)27-30-35-33(41)42-36-30/h18-21H,2-17,22-27H2,1H3,(H,34,40)(H,35,36,41)
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n/an/a 2.45E+4n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316462
PNG
(1-[4-(4,5-Dihydro-1,2,4-(4H)-5-oxo-oxadiazol-3-ylm...)
Show SMILES CCCCCCCCCCCCCCN1CCN(CC1)C(=O)Nc1ccc(Cc2nc(=O)o[nH]2)cc1
Show InChI InChI=1S/C28H45N5O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-18-32-19-21-33(22-20-32)27(34)29-25-16-14-24(15-17-25)23-26-30-28(35)36-31-26/h14-17H,2-13,18-23H2,1H3,(H,29,34)(H,30,31,35)
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n/an/a>2.50E+4n/an/an/an/an/an/a



Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50206904
PNG
((+/-)-1-O-benzyl-3-O-[4-(4,5-dihydro-5-oxo-1,2,4-4...)
Show SMILES CCCCCCCCCCCCCCOC(COCc1ccccc1)COc1ccc(cc1)-c1nc(=O)o[nH]1
Show InChI InChI=1S/C32H46N2O5/c1-2-3-4-5-6-7-8-9-10-11-12-16-23-37-30(25-36-24-27-17-14-13-15-18-27)26-38-29-21-19-28(20-22-29)31-33-32(35)39-34-31/h13-15,17-22,30H,2-12,16,23-26H2,1H3,(H,33,34,35)
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n/an/a>2.50E+4n/an/an/an/an/an/a



Université Paris7-Denis Diderot

Curated by ChEMBL


Assay Description
Inhibition of pig group IB PLA2 by fluorimetric assay

J Med Chem 50: 1618-26 (2007)


Article DOI: 10.1021/jm060082n
BindingDB Entry DOI: 10.7270/Q2TQ6174
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50316444
PNG
(1-[4-(4,5-Dihydro-1,2,4(4H)-5-oxo-oxadiazol-3-yl)b...)
Show SMILES CCCCCCCCCCCCCCN1CCN(Cc2ccc(cc2)-c2nc(=O)o[nH]2)C(=O)C1
Show InChI InChI=1S/C27H42N4O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-18-30-19-20-31(25(32)22-30)21-23-14-16-24(17-15-23)26-28-27(33)34-29-26/h14-17H,2-13,18-22H2,1H3,(H,28,29,33)
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Universit£ Paris Diderot

Curated by ChEMBL


Assay Description
Inhibition of porcine group 1B phospholipase A2 by fluorimetric assay

Bioorg Med Chem 18: 3588-600 (2010)


Article DOI: 10.1016/j.bmc.2010.03.049
BindingDB Entry DOI: 10.7270/Q2ZG6SD9
More data for this
Ligand-Target Pair
Phospholipase A2, major isoenzyme


(Sus scrofa (pig))		BDBM50031087
PNG
(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5...)
Show SMILES CS(=O)(=O)c1ccc(cc1)-c1[nH]c(SC#N)cc1-c1ccc(F)cc1
Show InChI InChI=1S/C18H13FN2O2S2/c1-25(22,23)15-8-4-13(5-9-15)18-16(10-17(21-18)24-11-20)12-2-6-14(19)7-3-12/h2-10,21H,1H3
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Du Pont Merck Pharmaceutical Company

Curated by ChEMBL


Assay Description
Inhibitory activity porcine pancreatic phospholipase-A2

J Med Chem 37: 988-98 (1994)


BindingDB Entry DOI: 10.7270/Q2BP01WP
More data for this
Ligand-Target Pair
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