Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23865 (3-[(2S)-2-[1-(9H-fluoren-9-yl)acetamido]-4-methylp...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8 | -10.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50543556 (CHEMBL4647187) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysis | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115433 BindingDB Entry DOI: 10.7270/Q2JM2F55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23866 (MDL28170 | Z-Val-Phe-CHO | benzyl N-[(1S)-2-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 10 | -10.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50014577 (CHEMBL286722 | MDL-2170 | Z-Val-Phe-H | [(S)-1-((S...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysis | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115433 BindingDB Entry DOI: 10.7270/Q2JM2F55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50543555 (CHEMBL4642092) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysis | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115433 BindingDB Entry DOI: 10.7270/Q2JM2F55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50543554 (CHEMBL4646991) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysis | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115433 BindingDB Entry DOI: 10.7270/Q2JM2F55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50543552 (CHEMBL4642290) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysis | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115433 BindingDB Entry DOI: 10.7270/Q2JM2F55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193489 ((R)-1-(4-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326300 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193501 ((R)-1-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193494 ((R)-1-(4-methoxyphenylsulfonyl)-N-((R,S)-1-oxo-3-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326298 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23859 (3-[(2S)-2-[1-(adamantan-1-yl)acetamido]-4-methylpe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 41 | -9.97 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193509 ((S)-3-(4-iodophenylsulfonyl)-N-((R,S)-1-oxo-3-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23857 (3-[(2S)-2-(3-cyclohexylpropanamido)-4-methylpentan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 50 | -9.85 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326303 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326304 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(6-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23863 (3-[(2S)-2-(3,3-diphenylpropanamido)-4-methylpentan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 63 | -9.72 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193503 ((4S)-N-(1-oxo-3-phenylpropan-2-yl)-3-tosylthiazoli...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193502 ((S)-3-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50244952 ((S)-2-ethyl-N-(1-oxo-3-phenylpropan-2-yl)-2-(3-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of pig erythrocyte mu-calpain | Bioorg Med Chem Lett 18: 4806-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.094 BindingDB Entry DOI: 10.7270/Q2V987W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193507 ((2R)-N-(1-oxo-3-phenylpropan-2-yl)-1-tosylpyrrolid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193490 ((S)-3-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23861 (3-[(2S)-2-(1,1-diphenylacetamido)-4-methylpentanam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 108 | -9.40 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193495 ((S)-3-(4-fluorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193504 ((R)-1-(4-bromophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 128 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193497 ((R)-1-(4-chlorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 141 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50084684 (CHEMBL333627 | {3-Methyl-1-[1-(3-morpholin-4-yl-pr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326299 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 165 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50069792 ((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of pig erythrocyte mu-calpain | Bioorg Med Chem Lett 18: 4806-8 (2008) Article DOI: 10.1016/j.bmcl.2008.07.094 BindingDB Entry DOI: 10.7270/Q2V987W2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193506 ((R)-1-(naphthalen-1-ylsulfonyl)-N-((R,S)-1-oxo-3-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 191 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193493 ((R)-N-((R,S)-1-oxo-3-phenylpropan-2-yl)-1-(phenyls...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 196 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326306 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 226 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193505 ((R)-1-(3-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 256 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50543553 (CHEMBL4640485) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 273 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of mu-calpain in porcine erythrocyte using Suc-Leu-Tyr-AMC as substrate by microtiter plate assay based Dixon plot analysis | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115433 BindingDB Entry DOI: 10.7270/Q2JM2F55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193500 ((R)-N-(2(R,S)-3,4-dioxo-4-(phenethylamino)-1-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193499 ((R)-1-(butylsulfonyl)-N-((R,S)-1-oxo-3-phenylpropa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 313 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193496 ((R)-1-(4-fluorophenylsulfonyl)-N-((R,S)-1-oxo-3-ph...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 386 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193508 ((R)-1-(2-nitrophenylsulfonyl)-N-((R,S)-1-oxo-3-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 424 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23858 (Peptidyl alpha-Ketoester, 1b | methyl 3-[(2S)-2-[1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 450 | -8.57 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193492 ((R)-N-(2(R,S)-3,4-dioxo-4-(phenethylamino)-1-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 450 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326301 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-amino-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326302 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326305 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(2-(dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 711 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193498 ((R)-1-(isopropylsulfonyl)-N-((R,S)-1-oxo-3-phenylp...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 836 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50193491 ((R)-N-(2(R,S)-3,4-dioxo-4-(phenethylamino)-1-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Tennessee Health Science Center Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte mu calpain | J Med Chem 49: 5282-90 (2006) Article DOI: 10.1021/jm050849w BindingDB Entry DOI: 10.7270/Q20C4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23860 (Peptidyl alpha-Ketoester, 1c | methyl 3-[(2S)-2-(1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 944 | -8.13 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23855 (Peptidyl alpha-Ketoester, 1a | methyl 3-[(2S)-2-(3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.05E+3 | -8.07 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM23864 (Peptidyl alpha-Ketoester, 1e | methyl 3-[(2S)-2-[1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.20E+3 | -7.99 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
University of Tennessee Health Science Center | Assay Description Assays were initiated by addition of CaCl2, and the increase in fluorescence (ex @370 nm, em @440 nm) was monitored. MDL28170 and buffer with 2% DMSO... | J Med Chem 51: 4346-50 (2008) Article DOI: 10.1021/jm800182c BindingDB Entry DOI: 10.7270/Q2542KW0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Calpain-1 catalytic subunit (Sus scrofa (pig)) | BDBM50326307 (3-(Benzyloxycarbonyl-L-leucylamino)-N-(3-(4-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Georgia Institute of Technology Curated by ChEMBL | Assay Description Inhibition of porcine erythrocyte calpain 1 | J Med Chem 53: 6326-36 (2010) Article DOI: 10.1021/jm901221v BindingDB Entry DOI: 10.7270/Q2KS6RR2 | |||||||||||
More data for this Ligand-Target Pair |
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