Found 376 hits of ic50 data for polymerid = 2457,49000583 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Gamma-aminobutyric acid type B receptor subunit 1
(Homo sapiens (Human)) | BDBM50435128
(CHEMBL2391908)Show SMILES C[C@H](NCC(=O)CP(O)(O)CC1CCCCC1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C18H28Cl2NO3P/c1-13(15-7-8-17(19)18(20)9-15)21-10-16(22)12-25(23,24)11-14-5-3-2-4-6-14/h7-9,13-14,21,23-25H,2-6,10-12H2,1H3/t13-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Broad Institute of MIT and Harvard
Curated by ChEMBL
| Assay Description
Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrs |
Bioorg Med Chem Lett 23: 1834-8 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.025
BindingDB Entry DOI: 10.7270/Q2P55PWC |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM104978
(US8575375, C-8)Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)C(CC[C@@H]2[N+]([O-])=O)C2CC[C@H]3C[C@](C)(O)CCC3C12 |r| Show InChI InChI=1S/C27H40N2O3/c1-26(30)14-13-20-18(15-26)7-10-21-23-11-12-24(29(31)32)27(23,2)16-22(25(20)21)17-5-8-19(9-6-17)28(3)4/h5-6,8-9,18,20-25,30H,7,10-16H2,1-4H3/t18-,20?,21?,22+,23?,24-,25?,26+,27-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 9.79 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute; The United States of America, as represented by the Secretary, Department of Health and Human Services
US Patent
| Assay Description
[35S]TBPS binding assay. |
US Patent US8575375 (2013)
BindingDB Entry DOI: 10.7270/Q2ST7NGT |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585990
(US11530237, Compound 165 | US11542297, Compound 16...)Show SMILES COC[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nc6ccc(Cl)cc6n5)[C@@]4(C)CC[C@H]23)C1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586009
(US11530237, Compound 185 | US11542297, Compound 18...)Show SMILES COC[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nnc6ccc(Cl)cc56)[C@@]4(C)CC[C@H]23)C1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586015
(US11530237, Compound 191 | US11542297, Compound 19...)Show SMILES COC[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5cc6cc(Cl)ccc6n5)[C@@]4(C)CC[C@H]23)C1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586026
(US11530237, Compound 204 | US11542297, Compound 20...)Show SMILES CCOC(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586065
(US11530237, Compound 246)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(F)cc2n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586067
(US11530237, Compound 248 | US11542297, Compound 24...)Show SMILES CSc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586066
(US11530237, Compound 247 | US11530237, Compound 24...)Show SMILES CSc1ccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc2c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586078
(US11530237, Compound 259 | US11542297, Compound 25...)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cnc(F)c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM586079
(US11530237, Compound 260 | US11542297, Compound 26...)Show SMILES CCCN(C)C(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585854
(US11530237, Compound 10 | US11542297, Compound 10)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc(cn1)C#N |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585855
(US11530237, Compound 11 | US11542297, Compound 11)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccccc2n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585856
(US11530237, Compound 12 | US11542297, Compound 12)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccccc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585858
(US11530237, Compound 14 | US11542297, Compound 14)Show SMILES COc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585859
(US11530237, Compound 15 | US11542297, Compound 15)Show SMILES COc1ccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc2c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585860
(US11530237, Compound 16 | US11542297, Compound 16)Show SMILES COc1ccc2nnn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)c2c1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585862
(US11530237, Compound 18 | US11542297, Compound 18)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2c(F)cccc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585863
(US11530237, Compound 19 | US11542297, Compound 19)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ccc(n1)C(F)(F)F |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585864
(US11530237, Compound 21 | US11542297, Compound 21)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(F)cc2n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585865
(US11530237, Compound 22 | US11542297, Compound 22)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccc(F)cc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585866
(US11530237, Compound 23 | US11542297, Compound 23)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)ccc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585867
(US11530237, Compound 24 | US11542297, Compound 24)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ccc(n1)C#N |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585868
(US11530237, Compound 26 | US11542297, Compound 26)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1cc2ccccc2n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585870
(US11530237, Compound 28 | US11542297, Compound 28)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2cc(F)cc(F)c2n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585871
(US11530237, Compound 29 | US11542297, Compound 29)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2cc(F)cc(F)c12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585874
(US11530237, Compound 32)Show SMILES Cc1nnn(CC(=O)[C@@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585877
(US11530237, Compound 35 | US11542297, Compound 35)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(Cl)cc2n1 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585878
(US11530237, Compound 36 | US11542297, Compound 36)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2ccc(Cl)cc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585882
(US11530237, Compound 40 | US11542297, Compound 40)Show SMILES CCO[C@H]1C[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5ccc(n5)C(=O)OCC)[C@@]4(C)CC[C@H]23)C[C@@H]1O |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585886
(US11530237, Compound 45 | US11542297, Compound 45)Show SMILES COc1cccc2n(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nnc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585891
(US11530237, Compound 50)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncc2cc(Cl)cnc12 |r| | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585894
(US11530237, Compound 53 | US11542297, Compound 53)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(Cl)c(F)c2n1 |r| | PDB
MMDB
KEGG
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B.MOAD
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| PC cid
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| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585895
(US11530237, Compound 54 | US11542297, Compound 54)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1ncnn1 |r| | PDB
MMDB
KEGG
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UniChem
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TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585915
(US11530237, Compound 74 | US11542297, Compound 74)Show SMILES CSc1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB
MMDB
KEGG
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B.MOAD
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| PC cid
PC sid
UniChem
| US Patent
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TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585919
(US11530237, Compound 78 | US11542297, Compound 78)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nnc2c(F)c(F)ccc12 |r| | PDB
MMDB
KEGG
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| PC cid
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UniChem
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TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585922
(US11530237, Compound 169 | US11530237, Compound 86...)Show SMILES CN(C)C(=O)c1cnn(CC(=O)[C@H]2CC[C@H]3[C@@H]4CC[C@@H]5C[C@](C)(O)CC[C@]5(C)[C@H]4CC[C@]23C)c1 |r| | PDB
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KEGG
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585932
(US11530237, Compound 103)Show SMILES CS(=O)c1ccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc2c1 |r| | PDB
MMDB
KEGG
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| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585933
(US11530237, Compound 104)Show SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@](C)(O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)Cn1nc2ccc(cc2n1)S(C)(=O)=O |r| | PDB
MMDB
KEGG
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| PC cid
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UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM585946
(US11530237, Compound 117 | US11542297, Compound 11...)Show SMILES COc1cccc2nn(CC(=O)[C@H]3CC[C@H]4[C@@H]5CC[C@H]6C[C@](C)(O)CC[C@]6(C)[C@H]5CC[C@]34C)nc12 |r| | PDB
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TBA
| Assay Description
TBD |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2XG9W00 |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403328
(US10329320, Compound 1 | US10329320, Compound 2)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nc5ccc(Cl)cc5n4)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C29H40ClN3O3/c1-27(35)12-13-29(17-36-3)18(15-27)4-6-20-21-7-8-23(28(21,2)11-10-22(20)29)26(34)16-33-31-24-9-5-19(30)14-25(24)32-33/h5,9,14,18,20-23,35H,4,6-8,10-13,15-17H2,1-3H3/t18-,20+,21+,22+,23-,27-,28+,29-/m1/s1 | PDB
MMDB
KEGG
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B.MOAD
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| PC cid
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UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403328
(US10329320, Compound 1 | US10329320, Compound 2)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nc5ccc(Cl)cc5n4)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C29H40ClN3O3/c1-27(35)12-13-29(17-36-3)18(15-27)4-6-20-21-7-8-23(28(21,2)11-10-22(20)29)26(34)16-33-31-24-9-5-19(30)14-25(24)32-33/h5,9,14,18,20-23,35H,4,6-8,10-13,15-17H2,1-3H3/t18-,20+,21+,22+,23-,27-,28+,29-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403330
(US10329320, Compound 7)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nnc5c(F)c(F)ccc45)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C29H39F2N3O3/c1-27(36)12-13-29(16-37-3)17(14-27)4-5-18-19-6-7-21(28(19,2)11-10-20(18)29)24(35)15-34-23-9-8-22(30)25(31)26(23)32-33-34/h8-9,17-21,36H,4-7,10-16H2,1-3H3/t17-,18-,19-,20-,21+,27+,28-,29+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403331
(US10329320, Compound 8)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nc5ccc(F)c(F)c5n4)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C29H39F2N3O3/c1-27(36)12-13-29(16-37-3)17(14-27)4-5-18-19-6-7-21(28(19,2)11-10-20(18)29)24(35)15-34-32-23-9-8-22(30)25(31)26(23)33-34/h8-9,17-21,36H,4-7,10-16H2,1-3H3/t17-,18-,19-,20-,21+,27+,28-,29+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403332
(US10329320, Compound 9)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nnc5c(F)cc(F)cc45)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C29H39F2N3O3/c1-27(36)10-11-29(16-37-3)17(14-27)4-5-19-20-6-7-22(28(20,2)9-8-21(19)29)25(35)15-34-24-13-18(30)12-23(31)26(24)32-33-34/h12-13,17,19-22,36H,4-11,14-16H2,1-3H3/t17-,19-,20-,21-,22+,27+,28-,29+/m0/s1 | PDB
MMDB
KEGG
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B.MOAD
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AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403333
(US10329320, Compound 10)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nc5cc(F)cc(F)c5n4)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C29H39F2N3O3/c1-27(36)10-11-29(16-37-3)17(14-27)4-5-19-20-6-7-22(28(20,2)9-8-21(19)29)25(35)15-34-32-24-13-18(30)12-23(31)26(24)33-34/h12-13,17,19-22,36H,4-11,14-16H2,1-3H3/t17-,19-,20-,21-,22+,27+,28-,29+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403334
(US10329320, Compound 11)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nnc5ncc(Cl)cc45)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C28H39ClN4O3/c1-26(35)10-11-28(16-36-3)17(13-26)4-5-19-20-6-7-22(27(20,2)9-8-21(19)28)24(34)15-33-23-12-18(29)14-30-25(23)31-32-33/h12,14,17,19-22,35H,4-11,13,15-16H2,1-3H3/t17-,19-,20-,21-,22+,26+,27-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403335
(US10329320, Compound 12)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nnc5cc(Cl)cnc45)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C28H39ClN4O3/c1-26(35)10-11-28(16-36-3)17(13-26)4-5-19-20-6-7-22(27(20,2)9-8-21(19)28)24(34)15-33-25-23(31-32-33)12-18(29)14-30-25/h12,14,17,19-22,35H,4-11,13,15-16H2,1-3H3/t17-,19-,20-,21-,22+,26+,27-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403336
(US10329320, Compound 13)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4nc5cc(Cl)cnc5n4)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C28H39ClN4O3/c1-26(35)10-11-28(16-36-3)17(13-26)4-5-19-20-6-7-22(27(20,2)9-8-21(19)28)24(34)15-33-31-23-12-18(29)14-30-25(23)32-33/h12,14,17,19-22,35H,4-11,13,15-16H2,1-3H3/t17-,19-,20-,21-,22+,26+,27-,28+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
More data for this
Ligand-Target Pair | |
Gamma-aminobutyric acid (GABA) B receptor 1
(Rattus norvegicus (rat)) | BDBM403337
(US10329320, Compound 14 | US11124538, Compound 14)Show SMILES COC[C@]12CC[C@@](C)(O)C[C@H]1CC[C@H]1[C@@H]3CC[C@H](C(=O)Cn4cc5ccc(F)cc5n4)[C@@]3(C)CC[C@H]21 |r| Show InChI InChI=1S/C30H41FN2O3/c1-28(35)12-13-30(18-36-3)20(15-28)5-7-22-23-8-9-25(29(23,2)11-10-24(22)30)27(34)17-33-16-19-4-6-21(31)14-26(19)32-33/h4,6,14,16,20,22-25,35H,5,7-13,15,17-18H2,1-3H3/t20-,22+,23+,24+,25-,28-,29+,30-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
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AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
SRMLSC
Curated by PubChem BioAssay
| Assay Description
TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987... |
PubChem Bioassay (2006)
BindingDB Entry DOI: 10.7270/Q22N54NV |
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Ligand-Target Pair | |
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