Compile Data Set for Download or QSAR

Found 104 hits of kd for UniProtKB: Q92769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19410 (CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	156	n/a	n/a	n/a	8.0	n/a
Genentech, Inc.					Assay Description Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19423 (HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C19H17N3O2S/c1-12(23)21-15-7-4-13(5-8-15)19(24)22-17-11-14(6-9-16(17)20)18-3-2-10-25-18/h2-11H,20H2,1H3,(H,21,23)(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	55.2	n/a	n/a	n/a	8.0	n/a
Genentech, Inc.					Assay Description Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50276074 (CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC2=O)CC1)-c1cccs1 Show InChI InChI=1S/C23H23N5O2S/c24-17-5-3-15(19-2-1-11-31-19)12-18(17)27-21(29)16-4-6-20(25-13-16)28-9-7-23(8-10-28)14-26-22(23)30/h1-6,11-13H,7-10,14,24H2,(H,26,30)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	48.1	n/a	n/a	n/a	8.0	n/a
Genentech, Inc.					Assay Description Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM50005711 (CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...) Show SMILES C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	15.3	n/a	n/a	n/a	8.0	n/a
Genentech, Inc.					Assay Description Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	182	n/a	n/a	n/a	8.0	n/a
Genentech, Inc.					Assay Description Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413916 (US10421756, Compound 100) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2cncnc2C1)-c1ccncc1 Show InChI InChI=1S/C18H16N6O/c19-15-2-1-13(12-3-5-20-6-4-12)7-16(15)23-18(25)24-9-14-8-21-11-22-17(14)10-24/h1-8,11H,9-10,19H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413917 (US10421756, Compound 101) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2nccnc2C1)-c1ccncc1 Show InChI InChI=1S/C18H16N6O/c19-14-2-1-13(12-3-5-20-6-4-12)9-15(14)23-18(25)24-10-16-17(11-24)22-8-7-21-16/h1-9H,10-11,19H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413918 (US10421756, Compound 102) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccncc1 Show InChI InChI=1S/C19H17N5O/c20-17-2-1-14(13-3-6-21-7-4-13)9-18(17)23-19(25)24-11-15-5-8-22-10-16(15)12-24/h1-10H,11-12,20H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413919 (US10421756, Compound 103) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccncn1 Show InChI InChI=1S/C18H16N6O/c19-15-2-1-12(16-4-6-21-11-22-16)7-17(15)23-18(25)24-9-13-3-5-20-8-14(13)10-24/h1-8,11H,9-10,19H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413920 (US10421756, Compound 104) Show SMILES CC(C)(C)OC(=O)N1CC2CC1CN2C(=O)Nc1cc(ccc1N)-c1ccncc1 Show InChI InChI=1S/C22H27N5O3/c1-22(2,3)30-21(29)27-13-16-11-17(27)12-26(16)20(28)25-19-10-15(4-5-18(19)23)14-6-8-24-9-7-14/h4-10,16-17H,11-13,23H2,1-3H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413921 (US10421756, Compound 105) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CCC(C1)O2)-c1ccncc1 Show InChI InChI=1S/C18H20N4O2/c19-16-4-1-13(12-5-7-20-8-6-12)9-17(16)21-18(23)22-10-14-2-3-15(11-22)24-14/h1,4-9,14-15H,2-3,10-11,19H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413922 (US10421756, Compound 106 | US10421756, Compound 11...) Show SMILES CC(C)(C)OC(=O)N1C2CCC1CN(C2)C(=O)Nc1cc(ccc1N)-c1ccncc1 |TLB:5:7:9.10:13.14.12| Show InChI InChI=1S/C23H29N5O3/c1-23(2,3)31-22(30)28-17-5-6-18(28)14-27(13-17)21(29)26-20-12-16(4-7-19(20)24)15-8-10-25-11-9-15/h4,7-12,17-18H,5-6,13-14,24H2,1-3H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413923 (US10421756, Compound 107 | US10421756, Compound 10...) Show SMILES CC(=O)N1C2CCC1CN(C2)C(=O)Nc1cc(ccc1N)-c1ccncc1 |TLB:1:3:5.6:9.10.8| Show InChI InChI=1S/C20H23N5O2/c1-13(26)25-16-3-4-17(25)12-24(11-16)20(27)23-19-10-15(2-5-18(19)21)14-6-8-22-9-7-14/h2,5-10,16-17H,3-4,11-12,21H2,1H3,(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413924 (US10421756, Compound 108) Show SMILES CC(=O)N1CC2CC1CN2C(=O)Nc1cc(ccc1N)-c1ccncc1 Show InChI InChI=1S/C19H21N5O2/c1-12(25)23-10-16-9-15(23)11-24(16)19(26)22-18-8-14(2-3-17(18)20)13-4-6-21-7-5-13/h2-8,15-16H,9-11,20H2,1H3,(H,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413923 (US10421756, Compound 107 | US10421756, Compound 10...) Show SMILES CC(=O)N1C2CCC1CN(C2)C(=O)Nc1cc(ccc1N)-c1ccncc1 |TLB:1:3:5.6:9.10.8| Show InChI InChI=1S/C20H23N5O2/c1-13(26)25-16-3-4-17(25)12-24(11-16)20(27)23-19-10-15(2-5-18(19)21)14-6-8-22-9-7-14/h2,5-10,16-17H,3-4,11-12,21H2,1H3,(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413922 (US10421756, Compound 106 | US10421756, Compound 11...) Show SMILES CC(C)(C)OC(=O)N1C2CCC1CN(C2)C(=O)Nc1cc(ccc1N)-c1ccncc1 |TLB:5:7:9.10:13.14.12| Show InChI InChI=1S/C23H29N5O3/c1-23(2,3)31-22(30)28-17-5-6-18(28)14-27(13-17)21(29)26-20-12-16(4-7-19(20)24)15-8-10-25-11-9-15/h4,7-12,17-18H,5-6,13-14,24H2,1-3H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413927 (US10421756, Compound 111) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CCC(C1)O2)-c1ccc(F)cc1 Show InChI InChI=1S/C19H20FN3O2/c20-14-4-1-12(2-5-14)13-3-8-17(21)18(9-13)22-19(24)23-10-15-6-7-16(11-23)25-15/h1-5,8-9,15-16H,6-7,10-11,21H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413928 (US10421756, Compound 112) Show SMILES CC(C)(C)OC(=O)N1C2CCC1CN(C2)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1 |TLB:5:7:9.10:13.14.12| Show InChI InChI=1S/C24H29FN4O3/c1-24(2,3)32-23(31)29-18-9-10-19(29)14-28(13-18)22(30)27-21-12-16(6-11-20(21)26)15-4-7-17(25)8-5-15/h4-8,11-12,18-19H,9-10,13-14,26H2,1-3H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413929 (US10421756, Compound 113) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CCC(C1)N2)-c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN4O/c20-14-4-1-12(2-5-14)13-3-8-17(21)18(9-13)23-19(25)24-10-15-6-7-16(11-24)22-15/h1-5,8-9,15-16,22H,6-7,10-11,21H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413930 (US10421756, Compound 114) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CNCC2C1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN4O/c20-16-4-1-12(2-5-16)13-3-6-17(21)18(7-13)23-19(25)24-10-14-8-22-9-15(14)11-24/h1-7,14-15,22H,8-11,21H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413931 (US10421756, Compound 115) Show SMILES CN1CC2CN(CC2C1=O)C(=O)Nc1cc(ccc1N)-c1ccncc1 Show InChI InChI=1S/C19H21N5O2/c1-23-9-14-10-24(11-15(14)18(23)25)19(26)22-17-8-13(2-3-16(17)20)12-4-6-21-7-5-12/h2-8,14-15H,9-11,20H2,1H3,(H,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413932 (US10421756, Compound 116) Show SMILES CC(=O)N1C2CCC1CN(C2)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1 |TLB:1:3:5.6:9.10.8| Show InChI InChI=1S/C21H23FN4O2/c1-13(27)26-17-7-8-18(26)12-25(11-17)21(28)24-20-10-15(4-9-19(20)23)14-2-5-16(22)6-3-14/h2-6,9-10,17-18H,7-8,11-12,23H2,1H3,(H,24,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413933 (US10421756, Compound 117) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CCC(C1)N2C=O)-c1ccc(F)cc1 |TLB:18:17:13.14:10.11.16| Show InChI InChI=1S/C20H21FN4O2/c21-15-4-1-13(2-5-15)14-3-8-18(22)19(9-14)23-20(27)24-10-16-6-7-17(11-24)25(16)12-26/h1-5,8-9,12,16-17H,6-7,10-11,22H2,(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413934 (US10421756, Compound 118) Show SMILES Nc1ccc(cc1NC(=O)N1CCC2(CCNC2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H25FN4O/c22-17-4-1-15(2-5-17)16-3-6-18(23)19(13-16)25-20(27)26-11-8-21(9-12-26)7-10-24-14-21/h1-6,13,24H,7-12,14,23H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413935 (US10421756, Compound 119) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2nccnc2C1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H16FN5O/c20-14-4-1-12(2-5-14)13-3-6-15(21)16(9-13)24-19(26)25-10-17-18(11-25)23-8-7-22-17/h1-9H,10-11,21H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413936 (US10421756, Compound 120) Show SMILES CNC(=O)N1CC2CN(CC2C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H24FN5O2/c1-24-20(28)26-9-15-11-27(12-16(15)10-26)21(29)25-19-8-14(4-7-18(19)23)13-2-5-17(22)6-3-13/h2-8,15-16H,9-12,23H2,1H3,(H,24,28)(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413937 (US10421756, Compound 121) Show SMILES NCC(=O)N1CC2CN(CC2C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H24FN5O2/c22-17-4-1-13(2-5-17)14-3-6-18(24)19(7-14)25-21(29)27-11-15-9-26(20(28)8-23)10-16(15)12-27/h1-7,15-16H,8-12,23-24H2,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413938 (US10421756, Compound 122) Show SMILES Nc1ccc(cc1NC(=O)c1cn2CCNCc2n1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H18FN5O/c20-14-4-1-12(2-5-14)13-3-6-15(21)16(9-13)24-19(26)17-11-25-8-7-22-10-18(25)23-17/h1-6,9,11,22H,7-8,10,21H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413939 (US10421756, Compound 123) Show SMILES Nc1ccc(cc1NC(=O)c1cn2CCNCc2n1)-c1ccncc1 Show InChI InChI=1S/C18H18N6O/c19-14-2-1-13(12-3-5-20-6-4-12)9-15(14)23-18(25)16-11-24-8-7-21-10-17(24)22-16/h1-6,9,11,21H,7-8,10,19H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413940 (US10421756, Compound 124) Show SMILES CC(C)(C)OC(=O)N1CC2CN(CC2C1)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1 Show InChI InChI=1S/C24H29FN4O3/c1-24(2,3)32-23(31)29-13-17-11-28(12-18(17)14-29)22(30)27-21-10-16(6-9-20(21)26)15-4-7-19(25)8-5-15/h4-10,17-18H,11-14,26H2,1-3H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413941 (US10421756, Compound 125) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CN(CC2C1)C(=O)C1CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H25FN4O2/c24-19-6-3-14(4-7-19)16-5-8-20(25)21(9-16)26-23(30)28-12-17-10-27(11-18(17)13-28)22(29)15-1-2-15/h3-9,15,17-18H,1-2,10-13,25H2,(H,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413942 (US10421756, Compound 126) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CN(CC2C1)C1COC1)-c1ccc(F)cc1 Show InChI InChI=1S/C22H25FN4O2/c23-18-4-1-14(2-5-18)15-3-6-20(24)21(7-15)25-22(28)27-10-16-8-26(9-17(16)11-27)19-12-29-13-19/h1-7,16-17,19H,8-13,24H2,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413943 (US10421756, Compound 127) Show SMILES Nc1ccc(cc1NC(=O)N1CCC2(COC2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN3O2/c21-16-4-1-14(2-5-16)15-3-6-17(22)18(11-15)23-19(25)24-9-7-20(8-10-24)12-26-13-20/h1-6,11H,7-10,12-13,22H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413944 (US10421756, Compound 128) Show SMILES Nc1ccc(cc1NC(=O)c1cn2CC(CCc2n1)C#N)-c1ccc(F)cc1 Show InChI InChI=1S/C21H18FN5O/c22-16-5-2-14(3-6-16)15-4-7-17(24)18(9-15)26-21(28)19-12-27-11-13(10-23)1-8-20(27)25-19/h2-7,9,12-13H,1,8,11,24H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413945 (US10421756, Compound 129) Show SMILES Nc1ccc(cc1NC(=O)N1CC2CN(CC2C1)C1COC1)-c1ccncc1 Show InChI InChI=1S/C21H25N5O2/c22-19-2-1-15(14-3-5-23-6-4-14)7-20(19)24-21(27)26-10-16-8-25(9-17(16)11-26)18-12-28-13-18/h1-7,16-18H,8-13,22H2,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413946 (US10421756, Compound 130) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17ClN4O/c21-17-4-1-13(2-5-17)14-3-6-18(22)19(9-14)24-20(26)25-11-15-7-8-23-10-16(15)12-25/h1-10H,11-12,22H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413947 (US10421756, Compound 131) Show SMILES Nc1ccc(cc1NC(=O)c1cn2CCNCc2n1)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C19H17F2N5O/c20-13-3-1-11(7-14(13)21)12-2-4-15(22)16(8-12)25-19(27)17-10-26-6-5-23-9-18(26)24-17/h1-4,7-8,10,23H,5-6,9,22H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413948 (US10421756, Compound 132) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccc(cc1F)C(F)(F)F Show InChI InChI=1S/C21H16F4N4O/c22-17-8-15(21(23,24)25)2-3-16(17)12-1-4-18(26)19(7-12)28-20(30)29-10-13-5-6-27-9-14(13)11-29/h1-9H,10-11,26H2,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413949 (US10421756, Compound 133) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccc(F)cc1F Show InChI InChI=1S/C20H16F2N4O/c21-15-2-3-16(17(22)8-15)12-1-4-18(23)19(7-12)25-20(27)26-10-13-5-6-24-9-14(13)11-26/h1-9H,10-11,23H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413950 (US10421756, Compound 134) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1cccnc1 Show InChI InChI=1S/C19H17N5O/c20-17-4-3-13(14-2-1-6-21-9-14)8-18(17)23-19(25)24-11-15-5-7-22-10-16(15)12-24/h1-10H,11-12,20H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413951 (US10421756, Compound 135) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C20H16F2N4O/c21-16-3-1-12(7-17(16)22)13-2-4-18(23)19(8-13)25-20(27)26-10-14-5-6-24-9-15(14)11-26/h1-9H,10-11,23H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413952 (US10421756, Compound 136) Show SMILES COCCN1CCC2(C1)CCN(CC2)C(=O)Nc1cc(ccc1N)-c1ccncc1 Show InChI InChI=1S/C23H31N5O2/c1-30-15-14-27-11-6-23(17-27)7-12-28(13-8-23)22(29)26-21-16-19(2-3-20(21)24)18-4-9-25-10-5-18/h2-5,9-10,16H,6-8,11-15,17,24H2,1H3,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413953 (US10421756, Compound 137) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2nccnc2C1)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C19H15F2N5O/c20-13-3-1-11(7-14(13)21)12-2-4-15(22)16(8-12)25-19(27)26-9-17-18(10-26)24-6-5-23-17/h1-8H,9-10,22H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413954 (US10421756, Compound 138) Show SMILES COCCN1CCC2(C1)CCN(CC2)C(=O)Nc1cc(ccc1N)-c1ccc(F)cc1 Show InChI InChI=1S/C24H31FN4O2/c1-31-15-14-28-11-8-24(17-28)9-12-29(13-10-24)23(30)27-22-16-19(4-7-21(22)26)18-2-5-20(25)6-3-18/h2-7,16H,8-15,17,26H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413955 (US10421756, Compound 139) Show SMILES COc1ccc(cc1)-c1ccc(N)c(NC(=O)N2Cc3ccncc3C2)c1 Show InChI InChI=1S/C21H20N4O2/c1-27-18-5-2-14(3-6-18)15-4-7-19(22)20(10-15)24-21(26)25-12-16-8-9-23-11-17(16)13-25/h2-11H,12-13,22H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413956 (US10421756, Compound 140) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H17F3N4O/c22-21(23,24)17-4-1-13(2-5-17)14-3-6-18(25)19(9-14)27-20(29)28-11-15-7-8-26-10-16(15)12-28/h1-10H,11-12,25H2,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413957 (US10421756, Compound 141) Show SMILES Cc1cc(F)ccc1-c1ccc(N)c(NC(=O)N2Cc3ccncc3C2)c1 Show InChI InChI=1S/C21H19FN4O/c1-13-8-17(22)3-4-18(13)14-2-5-19(23)20(9-14)25-21(27)26-11-15-6-7-24-10-16(15)12-26/h2-10H,11-12,23H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413958 (US10421756, Compound 142) Show SMILES Nc1ccc(cc1NC(=O)N1Cc2ccncc2C1)-c1cc(F)c(F)c(F)c1 Show InChI InChI=1S/C20H15F3N4O/c21-15-5-13(6-16(22)19(15)23)11-1-2-17(24)18(7-11)26-20(28)27-9-12-3-4-25-8-14(12)10-27/h1-8H,9-10,24H2,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413959 (US10421756, Compound 143) Show SMILES Nc1ccc(cc1NC(=O)N1CCC2(CCN(CCF)C2)CC1)-c1ccc(F)cc1 Show InChI InChI=1S/C23H28F2N4O/c24-10-14-28-11-7-23(16-28)8-12-29(13-9-23)22(30)27-21-15-18(3-6-20(21)26)17-1-4-19(25)5-2-17/h1-6,15H,7-14,16,26H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair
Histone deacetylase 2 (Homo sapiens (Human))	BDBM413960 (US10421756, Compound 144) Show SMILES Nc1ccc(cc1NC(=O)N1CCC2(CCN(CCF)C2)CC1)-c1ccncc1 Show InChI InChI=1S/C22H28FN5O/c23-8-14-27-11-5-22(16-27)6-12-28(13-7-22)21(29)26-20-15-18(1-2-19(20)24)17-3-9-25-10-4-17/h1-4,9-10,15H,5-8,11-14,16,24H2,(H,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a
Rodin Therapeutics, Inc. US Patent					Assay Description HDAC2 containing a C-terminal HIS-Tag (Proteros) and fluorescently-labeled anti-HIS-antibody are diluted in one vial in assay buffer 50 mM Tris, pH 8...				US Patent US10421756 (2019) BindingDB Entry DOI: 10.7270/Q2PK0JGK
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 104 total )  |  Next  |  Last  >>

Jump to: