Compile Data Set for Download or QSAR

Found 16 hits of ki data for polymerid = 2965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50574654 (CHEMBL4870906) Show SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2cccc(c2)C(F)(F)F)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113679 BindingDB Entry DOI: 10.7270/Q2NV9P2Q
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50574655 (CHEMBL4852896) Show SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2cccc(Cl)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113679 BindingDB Entry DOI: 10.7270/Q2NV9P2Q
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50574656 (CHEMBL4866490) Show SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2cccc(OC(F)(F)F)c2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant MAGL assessed as dissociation constant using 4-NPA as substrate				Citation and Details Article DOI: 10.1016/j.ejmech.2021.113679 BindingDB Entry DOI: 10.7270/Q2NV9P2Q
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50605682 (CHEMBL5176915) Show SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(Cc2cccc(Oc3cc(ccn3)C(F)(F)F)c2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01806 BindingDB Entry DOI: 10.7270/Q2Q81J4P
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562160 (CHEMBL4757403) Show SMILES Oc1cc(C(=O)N2CCC(CC2)C(=O)c2ccc(Sc3ccccc3)cc2)c(F)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50540526 (CHEMBL4637658) Show SMILES Clc1cccc(NC(=O)C2CCN(CC2)C(=O)c2ccc3ccccc3c2)c1 Show InChI InChI=1S/C23H21ClN2O2/c24-20-6-3-7-21(15-20)25-22(27)17-10-12-26(13-11-17)23(28)19-9-8-16-4-1-2-5-18(16)14-19/h1-9,14-15,17H,10-13H2,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL at 31.25 nM to 125 nM pre-incubated for 5 mins before MAGL substrate addition and further incubated ...				J Med Chem 63: 5783-5796 (2020) Article DOI: 10.1021/acs.jmedchem.9b02137 BindingDB Entry DOI: 10.7270/Q2GQ7288
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562158 (CHEMBL4747585) Show SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Sc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562161 (CHEMBL4755606) Show SMILES Oc1cc(C(=O)N2CCC(CC2)C(=O)c2ccc(Cc3ccccc3)cc2)c(F)cc1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562159 (CHEMBL4798508) Show SMILES Oc1ccc(F)c(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cc2ccccc2)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531972 (CHEMBL4536045) Show SMILES CC(C)c1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1cc(O)ccc1F Show InChI InChI=1S/C22H24FNO3/c1-14(2)15-3-5-16(6-4-15)21(26)17-9-11-24(12-10-17)22(27)19-13-18(25)7-8-20(19)23/h3-8,13-14,17,25H,9-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten-based plot analysis				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483 BindingDB Entry DOI: 10.7270/Q2GM8BSN
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50600140 (CHEMBL5174588) Show SMILES CS(=O)(=O)c1ccc(NC(=O)N\N=C/c2c(Cl)cccc2Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116698 BindingDB Entry DOI: 10.7270/Q22B933P
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50394369 (CHEMBL2159781) Show SMILES O=C(N1CCN(CC1)C(c1ccccc1)c1ccccc1)n1nnc2ccccc12 Show InChI InChI=1S/C24H23N5O/c30-24(29-22-14-8-7-13-21(22)25-26-29)28-17-15-27(16-18-28)23(19-9-3-1-4-10-19)20-11-5-2-6-12-20/h1-14,23H,15-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Irreversible inhibition of human MAGL using p-nitrophenylpropionate as substrate				Bioorg Med Chem 20: 6260-75 (2012) Article DOI: 10.1016/j.bmc.2012.09.011 BindingDB Entry DOI: 10.7270/Q2W37XDX
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Monoglyceride lipase (Homo sapiens (Human))	BDBM50255235 (CHEMBL4078924) Show SMILES Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1 Show InChI InChI=1S/C30H31N3O2/c1-22-6-5-9-25(18-22)21-33-29(26-10-12-27(34)13-11-26)20-28(31-33)30(35)32-16-14-24(15-17-32)19-23-7-3-2-4-8-23/h2-13,18,20,24,34H,14-17,19,21H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	412	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemical and Pharmaceutical Sciences, University of Ferrara , 44121 Ferrara, Italy. Curated by ChEMBL					Assay Description Competitive inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten plot analysis				J Med Chem 61: 1340-1354 (2018) Article DOI: 10.1021/acs.jmedchem.7b01845 BindingDB Entry DOI: 10.7270/Q2JM2D3V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50470454 (CHEMBL4282040) Show SMILES Oc1cccc(c1)C(=O)N1CCC(CC1)C(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClNO3/c20-16-6-4-13(5-7-16)18(23)14-8-10-21(11-9-14)19(24)15-2-1-3-17(22)12-15/h1-7,12,14,22H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human recombinant MAGL using 4-NPA substrate incubated for 30 mins by Michaelis-Menten kinetics analysis				Citation and Details BindingDB Entry DOI: 10.7270/Q20868X2
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50379241 (CHEMBL2011479) Show SMILES O=C(Cc1ccc(Cc2ccccc2)cc1)OC[C@H]1CO1 |r| Show InChI InChI=1S/C18H18O3/c19-18(21-13-17-12-20-17)11-16-8-6-15(7-9-16)10-14-4-2-1-3-5-14/h1-9,17H,10-13H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Non-competitive inhibition of human recombinant MAGL assessed as 7-hydroxycoumarin level using umbelliferyl arachidonate as substrate by luminescence...				J Med Chem 55: 824-36 (2012) Article DOI: 10.1021/jm201327p BindingDB Entry DOI: 10.7270/Q2B27W9V
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50479142 (Guineensine | Guineesine | Pipyahyine) Show SMILES CC(C)CNC(=O)\C=C\C=C\CCCCCC\C=C\c1ccc2OCOc2c1 Show InChI InChI=1S/C24H33NO3/c1-20(2)18-25-24(26)14-12-10-8-6-4-3-5-7-9-11-13-21-15-16-22-23(17-21)28-19-27-22/h8,10-17,20H,3-7,9,18-19H2,1-2H3,(H,25,26)/b10-8+,13-11+,14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Concordia University Wisconsin Curated by ChEMBL					Assay Description Inhibition of MAGL in human U937 cell homogenates using [3H]-2OG as substrate preincubated for 15 mins followed by substrate addition and measured af...				J Nat Prod 82: 636-646 (2019) Article DOI: 10.1021/acs.jnatprod.8b00874 BindingDB Entry DOI: 10.7270/Q2P55RZ3
					More data for this Ligand-Target Pair