Found 22 hits of ki data for polymerid = 3423 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50046201
((2E)-2-((2E)-2-{[(E)-amino(imino)methyl]hydrazono}...)Show SMILES [#6]-[#6](-[#6]=[#7]-[#7]-[#6](-[#7])=[#7])=[#7]\[#7]=[#6](\[#7])-[#7] |w:3.3,8.8| Show InChI InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
Inhibition of rat liver form of S-adenosyl-methionine decarboxylase enzyme |
J Med Chem 44: 1-26 (2001)
BindingDB Entry DOI: 10.7270/Q28S4QNR |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50403124
(CHEMBL2115571)Show SMILES C[S+](CCC(N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7?,8-,10-,11-,14-,27?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uM |
Bioorg Med Chem Lett 3: 2811-2816 (1993)
Article DOI: 10.1016/S0960-894X(01)80770-8
BindingDB Entry DOI: 10.7270/Q2TH8N6T |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50281293
(2-amino-5-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)Show SMILES Br.[Br-].C[S+](CCCC(N)C#N)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C16H24N7O3S/c1-27(4-2-3-9(18)5-17)6-10-12(24)13(25)16(26-10)23-8-22-11-14(19)20-7-21-15(11)23/h7-10,12-13,16,24-25H,2-4,6,18H2,1H3,(H2,19,20,21)/q+1/p+1/t9?,10-,12-,13-,16?,27?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was evaluated to inactivate the human AdoMet-DC |
Bioorg Med Chem Lett 3: 2811-2816 (1993)
Article DOI: 10.1016/S0960-894X(01)80770-8
BindingDB Entry DOI: 10.7270/Q2TH8N6T |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50403124
(CHEMBL2115571)Show SMILES C[S+](CCC(N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7?,8-,10-,11-,14-,27?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was evaluated to inactivate the human AdoMet-DC; value ranges from 10.7 to 62.7 uM |
Bioorg Med Chem Lett 3: 2811-2816 (1993)
Article DOI: 10.1016/S0960-894X(01)80770-8
BindingDB Entry DOI: 10.7270/Q2TH8N6T |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50403124
(CHEMBL2115571)Show SMILES C[S+](CCC(N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7?,8-,10-,11-,14-,27?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uM |
Bioorg Med Chem Lett 3: 2811-2816 (1993)
Article DOI: 10.1016/S0960-894X(01)80770-8
BindingDB Entry DOI: 10.7270/Q2TH8N6T |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366321
(CHEMBL3392203 | CHEMBL606101)Show SMILES OS(O)(=O)=O.OS([O-])(=O)=O.C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C1C[C@@H](N)C=C1 |r,c:35| Show InChI InChI=1S/C16H23N6O3S/c1-26(9-3-2-8(17)4-9)5-10-12(23)13(24)16(25-10)22-7-21-11-14(18)19-6-20-15(11)22/h2-3,6-10,12-13,16,23-24H,4-5,17H2,1H3,(H2,18,19,20)/q+1/p+1/t8-,9?,10+,12+,13+,16?,26?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50034925
(CHEMBL299398 | O-{(1S,4S)-4-[6-(6-Amino-purin-9-yl...)Show SMILES CC1(C)OC2C(CS[C@H]3C[C@H](ON)C=C3)OC(C2O1)n1cnc2c(N)ncnc12 |c:13| Show InChI InChI=1S/C18H24N6O4S/c1-18(2)26-13-11(6-29-10-4-3-9(5-10)28-20)25-17(14(13)27-18)24-8-23-12-15(19)21-7-22-16(12)24/h3-4,7-11,13-14,17H,5-6,20H2,1-2H3,(H2,19,21,22)/t9-,10-,11?,13?,14?,17?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
compound was evaluated for the inhibitor constant against Escherichia coli S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50368997
(CHEMBL1791422)Show SMILES C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)[C@@H]1C[C@@H](O[NH3+])C=C1 |r,c:28| Show InChI InChI=1S/C16H24N6O4S/c1-27(9-3-2-8(4-9)26-18)5-10-12(23)13(24)16(25-10)22-7-21-11-14(17)19-6-20-15(11)22/h2-3,6-10,12-13,16,23-24H,4-5H2,1,18H3,(H2,17,19,20)/q+2/t8-,9-,10+,12+,13+,16+,27?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
compound was evaluated for the inhibitor constant against human S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50034925
(CHEMBL299398 | O-{(1S,4S)-4-[6-(6-Amino-purin-9-yl...)Show SMILES CC1(C)OC2C(CS[C@H]3C[C@H](ON)C=C3)OC(C2O1)n1cnc2c(N)ncnc12 |c:13| Show InChI InChI=1S/C18H24N6O4S/c1-18(2)26-13-11(6-29-10-4-3-9(5-10)28-20)25-17(14(13)27-18)24-8-23-12-15(19)21-7-22-16(12)24/h3-4,7-11,13-14,17H,5-6,20H2,1-2H3,(H2,19,21,22)/t9-,10-,11?,13?,14?,17?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
compound was evaluated for the inhibitor constant against Escherichia coli S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50368997
(CHEMBL1791422)Show SMILES C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)[C@@H]1C[C@@H](O[NH3+])C=C1 |r,c:28| Show InChI InChI=1S/C16H24N6O4S/c1-27(9-3-2-8(4-9)26-18)5-10-12(23)13(24)16(25-10)22-7-21-11-14(17)19-6-20-15(11)22/h2-3,6-10,12-13,16,23-24H,4-5H2,1,18H3,(H2,17,19,20)/q+2/t8-,9-,10+,12+,13+,16+,27?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
compound was evaluated for the inhibitor constant against Escherichia coli S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50368996
(CHEMBL1791421)Show SMILES C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)[C@H]1C[C@H](O[NH3+])C=C1 |r,c:28| Show InChI InChI=1S/C16H24N6O4S/c1-27(9-3-2-8(4-9)26-18)5-10-12(23)13(24)16(25-10)22-7-21-11-14(17)19-6-20-15(11)22/h2-3,6-10,12-13,16,23-24H,4-5H2,1,18H3,(H2,17,19,20)/q+2/t8-,9-,10-,12-,13-,16-,27?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibitor constant against Escherichia coli S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50368996
(CHEMBL1791421)Show SMILES C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)[C@H]1C[C@H](O[NH3+])C=C1 |r,c:28| Show InChI InChI=1S/C16H24N6O4S/c1-27(9-3-2-8(4-9)26-18)5-10-12(23)13(24)16(25-10)22-7-21-11-14(17)19-6-20-15(11)22/h2-3,6-10,12-13,16,23-24H,4-5H2,1,18H3,(H2,17,19,20)/q+2/t8-,9-,10-,12-,13-,16-,27?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
Compound was evaluated for the inhibitor constant against Escherichia coli S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50281292
(2-amino-4-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)Show SMILES Br.[Br-].C[S+](CCC(N)C#N)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C15H22N7O3S/c1-26(3-2-8(17)4-16)5-9-11(23)12(24)15(25-9)22-7-21-10-13(18)19-6-20-14(10)22/h6-9,11-12,15,23-24H,2-3,5,17H2,1H3,(H2,18,19,20)/q+1/p+1/t8?,9-,11-,12-,15?,26?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 3.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was evaluated to inactivate the bacterial AdoMet-DC |
Bioorg Med Chem Lett 3: 2811-2816 (1993)
Article DOI: 10.1016/S0960-894X(01)80770-8
BindingDB Entry DOI: 10.7270/Q2TH8N6T |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50034927
(CHEMBL48973 | O-{(1R,4R)-4-[6-(6-Amino-purin-9-yl)...)Show SMILES CC1(C)OC2C(CS[C@@H]3C[C@@H](ON)C=C3)OC(C2O1)n1cnc2c(N)ncnc12 |c:13| Show InChI InChI=1S/C18H24N6O4S/c1-18(2)26-13-11(6-29-10-4-3-9(5-10)28-20)25-17(14(13)27-18)24-8-23-12-15(19)21-7-22-16(12)24/h3-4,7-11,13-14,17H,5-6,20H2,1-2H3,(H2,19,21,22)/t9-,10-,11?,13?,14?,17?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 9.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
compound was evaluated for the inhibitory constant against human S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50034927
(CHEMBL48973 | O-{(1R,4R)-4-[6-(6-Amino-purin-9-yl)...)Show SMILES CC1(C)OC2C(CS[C@@H]3C[C@@H](ON)C=C3)OC(C2O1)n1cnc2c(N)ncnc12 |c:13| Show InChI InChI=1S/C18H24N6O4S/c1-18(2)26-13-11(6-29-10-4-3-9(5-10)28-20)25-17(14(13)27-18)24-8-23-12-15(19)21-7-22-16(12)24/h3-4,7-11,13-14,17H,5-6,20H2,1-2H3,(H2,19,21,22)/t9-,10-,11?,13?,14?,17?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 9.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University
Curated by ChEMBL
| Assay Description
compound was evaluated for the inhibitory constant against human S-adenosyl-L-methionine decarboxylase |
J Med Chem 38: 1770-7 (1995)
BindingDB Entry DOI: 10.7270/Q2X92BX3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50281292
(2-amino-4-({[(2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-...)Show SMILES Br.[Br-].C[S+](CCC(N)C#N)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C15H22N7O3S/c1-26(3-2-8(17)4-16)5-9-11(23)12(24)15(25-9)22-7-21-10-13(18)19-6-20-14(10)22/h6-9,11-12,15,23-24H,2-3,5,17H2,1H3,(H2,18,19,20)/q+1/p+1/t8?,9-,11-,12-,15?,26?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 2.47E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was evaluated to inactivate the human AdoMet-DC |
Bioorg Med Chem Lett 3: 2811-2816 (1993)
Article DOI: 10.1016/S0960-894X(01)80770-8
BindingDB Entry DOI: 10.7270/Q2TH8N6T |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366318
(CHEMBL3392208 | CHEMBL605698)Show SMILES OS(O)(=O)=O.Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CSC2CCNC2)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C14H20N6O3S/c15-12-9-13(18-5-17-12)20(6-19-9)14-11(22)10(21)8(23-14)4-24-7-1-2-16-3-7/h5-8,10-11,14,16,21-22H,1-4H2,(H2,15,17,18)/t7?,8-,10-,11-,14?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 4.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366320
(CHEMBL3392206 | CHEMBL605899)Show SMILES OS(O)(=O)=O.Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CS[C@@H]2CN[C@@H](C2)C(O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C15H20N6O5S/c16-12-9-13(19-4-18-12)21(5-20-9)14-11(23)10(22)8(26-14)3-27-6-1-7(15(24)25)17-2-6/h4-8,10-11,14,17,22-23H,1-3H2,(H,24,25)(H2,16,18,19)/t6-,7+,8-,10-,11-,14?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 4.78E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366317
(CHEMBL3392204 | CHEMBL606102)Show SMILES OS(O)(=O)=O.OS([O-])(=O)=O.C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C1CCNC1 |r| Show InChI InChI=1S/C15H23N6O3S/c1-25(8-2-3-17-4-8)5-9-11(22)12(23)15(24-9)21-7-20-10-13(16)18-6-19-14(10)21/h6-9,11-12,15,17,22-23H,2-5H2,1H3,(H2,16,18,19)/q+1/p+1/t8?,9-,11-,12-,15?,25?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 6.69E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366316
(CHEMBL3392209 | CHEMBL605267)Show SMILES OS(O)(=O)=O.Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CS[C@H]2CN[C@@H](C2)C(O)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C15H20N6O5S/c16-12-9-13(19-4-18-12)21(5-20-9)14-11(23)10(22)8(26-14)3-27-6-1-7(15(24)25)17-2-6/h4-8,10-11,14,17,22-23H,1-3H2,(H,24,25)(H2,16,18,19)/t6-,7-,8+,10+,11+,14?/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 9.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366319
(CHEMBL1791405 | CHEMBL3392205)Show SMILES OS(O)(=O)=O.OS([O-])(=O)=O.C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C1CN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C16H22N6O5S/c1-28(7-2-8(16(25)26)18-3-7)4-9-11(23)12(24)15(27-9)22-6-21-10-13(17)19-5-20-14(10)22/h5-9,11-12,15,18,23-24H,2-4H2,1H3,(H2-,17,19,20,25,26)/p+2/t7-,8+,9-,11-,12-,15-,28?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.07E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
S-adenosylmethionine decarboxylase proenzyme
(Homo sapiens (Human)) | BDBM50366319
(CHEMBL1791405 | CHEMBL3392205)Show SMILES OS(O)(=O)=O.OS([O-])(=O)=O.C[S+](C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C1CN[C@@H](C1)C(O)=O |r| Show InChI InChI=1S/C16H22N6O5S/c1-28(7-2-8(16(25)26)18-3-7)4-9-11(23)12(24)15(27-9)22-6-21-10-13(17)19-5-20-14(10)22/h5-9,11-12,15,18,23-24H,2-4H2,1H3,(H2-,17,19,20,25,26)/p+2/t7-,8+,9-,11-,12-,15-,28?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| 1.07E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Tested for irreversible inhibitory activity against AdoMet-DC (S-adenosyl-methionine decarboxylase-) isolated from Escherichia coli |
Bioorg Med Chem Lett 3: 147-152 (1993)
Article DOI: 10.1016/S0960-894X(01)80865-9
BindingDB Entry DOI: 10.7270/Q2PR7WG3 |
More data for this
Ligand-Target Pair | |
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