BindingDB PrimarySearch

Found 13 hits of kd data for polymerid = 3609
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50585157 (CHEMBL5087665) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to recombinant human iNOS assessed as dissociation constant by surface plasmon resonance assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00578 BindingDB Entry DOI: 10.7270/Q2H9993V
TBA					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50346532 ((R)-pyrrolidine-2-carboximidamide \| CHEMBL1783097) Show SMILES NC(=N)[C@H]1CCCN1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to human recombinant iNOS delta 65 residue				Bioorg Med Chem Lett 21: 3037-40 (2011) Article DOI: 10.1016/j.bmcl.2011.03.038 BindingDB Entry DOI: 10.7270/Q2FB538T
GlaxoSmithKline R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM130385 (6(3amino2{5[2(6amino4methylpyridin2 yl)ethyl]pyrid...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.19E+3	n/a	n/a	n/a	7.5	25
University of California at Irvine					Assay Description The buffer contained 50 mM HEPES (pH 7.5), 10% glycerol, and 100 mM NaCl, containing 1 mM imidazole. The spectral shift was monitored for a few minut...				Biochemistry 53: 5272-9 (2014) Article DOI: 10.1021/bi500561h BindingDB Entry DOI: 10.7270/Q2N01573
University of California at Irvine					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50374677 (CHEMBL405231) Show SMILES NNC(=N)NCCC[C@H](N)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to truncated iNOS construct (1-490) by spectral assay				J Med Chem 51: 924-31 (2008) Article DOI: 10.1021/jm701119v BindingDB Entry DOI: 10.7270/Q2639QMP
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50230418 (CHEMBL260629 \| N(gamma)-hydroxy-L-arginine \| N-OME...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	n/a	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a
University of Utrecht Curated by ChEMBL					Assay Description Binding affinity to iNOS with heme domain construct (unknown origin) assessed as spectral binding constant by spectral assay				Bioorg Med Chem Lett 19: 1758-62 (2009) Article DOI: 10.1016/j.bmcl.2009.01.076 BindingDB Entry DOI: 10.7270/Q2P55NC7
University of Utrecht Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM21959 ((2S)-2-amino-5-carbamimidamidopentanoic acid \| ARG...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a
University of Utrecht Curated by ChEMBL					Assay Description Binding affinity to iNOS with heme domain construct (unknown origin) assessed as spectral binding constant by spectral assay				Bioorg Med Chem Lett 19: 1758-62 (2009) Article DOI: 10.1016/j.bmcl.2009.01.076 BindingDB Entry DOI: 10.7270/Q2P55NC7
University of Utrecht Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM21959 ((2S)-2-amino-5-carbamimidamidopentanoic acid \| ARG...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to truncated iNOS construct (1-490) by spectral assay				J Med Chem 51: 924-31 (2008) Article DOI: 10.1021/jm701119v BindingDB Entry DOI: 10.7270/Q2639QMP
University of California Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50374674 (CHEMBL408756) Show SMILES CN(N)C(=N)NCCC[C@H](N)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to truncated iNOS construct (1-490) by spectral assay				J Med Chem 51: 924-31 (2008) Article DOI: 10.1021/jm701119v BindingDB Entry DOI: 10.7270/Q2639QMP
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50374676 (CHEMBL272814) Show SMILES CNNC(=N)NCCC[C@H](N)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to truncated iNOS construct (1-490) by spectral assay				J Med Chem 51: 924-31 (2008) Article DOI: 10.1021/jm701119v BindingDB Entry DOI: 10.7270/Q2639QMP
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50346533 ((S)-pyrrolidine-2-carboximidamide \| CHEMBL1783098) Show SMILES NC(=N)[C@@H]1CCCN1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Binding affinity to human recombinant iNOS delta 65 residue				Bioorg Med Chem Lett 21: 3037-40 (2011) Article DOI: 10.1016/j.bmcl.2011.03.038 BindingDB Entry DOI: 10.7270/Q2FB538T
GlaxoSmithKline R&D Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50374675 (CHEMBL272851) Show SMILES N[C@@H](CCCNC(=N)N(N)CC(F)(F)F)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity to truncated iNOS construct (1-490) by spectral assay				J Med Chem 51: 924-31 (2008) Article DOI: 10.1021/jm701119v BindingDB Entry DOI: 10.7270/Q2639QMP
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50266728 (4,4-difluoro-N(gamma)-hydroxy-L-arginine \| CHEMBL4...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a
University of Utrecht Curated by ChEMBL					Assay Description Binding affinity to iNOS with heme domain construct (unknown origin) assessed as spectral binding constant by spectral assay				Bioorg Med Chem Lett 19: 1758-62 (2009) Article DOI: 10.1016/j.bmcl.2009.01.076 BindingDB Entry DOI: 10.7270/Q2P55NC7
University of Utrecht Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50266727 (4,4-Difluoro-L-arginine \| CHEMBL476416) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.10E+6	n/a	n/a	n/a	n/a	n/a
University of Utrecht Curated by ChEMBL					Assay Description Binding affinity to iNOS with heme domain construct (unknown origin) assessed as spectral binding constant by spectral assay				Bioorg Med Chem Lett 19: 1758-62 (2009) Article DOI: 10.1016/j.bmcl.2009.01.076 BindingDB Entry DOI: 10.7270/Q2P55NC7
University of Utrecht Curated by ChEMBL					More data for this Ligand-Target Pair