Compile Data Set for Download or QSAR

Found 18 hits of non-affinity data for polymerid = 369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM19918 (3-arylquinazolinone, 1aj | 5-hydroxy-7-methoxy-3-(...) Show SMILES COc1ccc(cc1)-n1cnc2cc(OC)cc(O)c2c1=O Show InChI InChI=1S/C16H14N2O4/c1-21-11-5-3-10(4-6-11)18-9-17-13-7-12(22-2)8-14(19)15(13)16(18)20/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM22433 (4-hydroxytamoxifen (4-OHT) analog, 13 | N-[(4Z)-5-...) Show SMILES CN(C)CCOc1ccc(cc1)C(=C(\CCCNC(C)=O)c1ccccc1)\c1ccc(O)cc1 Show InChI InChI=1S/C29H34N2O3/c1-22(32)30-19-7-10-28(23-8-5-4-6-9-23)29(24-11-15-26(33)16-12-24)25-13-17-27(18-14-25)34-21-20-31(2)3/h4-6,8-9,11-18,33H,7,10,19-21H2,1-3H3,(H,30,32)/b29-28-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Binding affinity was measured by a scintillation proximity binding assay using [3H]4-OHT (for ERRgamma) or [3H]estradiol (for ERalpha) as radioligand...				Bioorg Med Chem Lett 16: 821-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.030 BindingDB Entry DOI: 10.7270/Q2WW7FZ7
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19923 (3-arylquinazolinone, 1an | 5,7-dihydroxy-3-(4-hydr...) Show SMILES Oc1ccc(cc1)-n1cnc2c(I)c(O)c(I)c(O)c2c1=O Show InChI InChI=1S/C14H8I2N2O4/c15-9-11-8(12(20)10(16)13(9)21)14(22)18(5-17-11)6-1-3-7(19)4-2-6/h1-5,19-21H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19925 (3-arylquinazolinone, 1ap | 5,7-dihydroxy-3-(4-hydr...) Show SMILES Oc1ccc(cc1)-n1cnc2cc(O)c(I)c(O)c2c1=O Show InChI InChI=1S/C14H9IN2O4/c15-12-10(19)5-9-11(13(12)20)14(21)17(6-16-9)7-1-3-8(18)4-2-7/h1-6,18-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19935 (3-arylquinazolinone, 1aab | 5-hydroxy-3-(4-hydroxy...) Show SMILES COc1cc(O)c2c(c1)[nH]c(=S)n(-c1ccc(O)cc1)c2=O Show InChI InChI=1S/C15H12N2O4S/c1-21-10-6-11-13(12(19)7-10)14(20)17(15(22)16-11)8-2-4-9(18)5-3-8/h2-7,18-19H,1H3,(H,16,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19937 (2-chloro-5,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dih...) Show SMILES Oc1ccc(cc1)-n1c(Cl)nc2cc(O)cc(O)c2c1=O Show InChI InChI=1S/C14H9ClN2O4/c15-14-16-10-5-9(19)6-11(20)12(10)13(21)17(14)7-1-3-8(18)4-2-7/h1-6,18-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19939 (3-arylquinazolinone, 1aaf | 7-hydroxy-3-(4-hydroxy...) Show SMILES Cc1nc2cc(O)ccc2c(=O)n1-c1ccc(O)cc1 Show InChI InChI=1S/C15H12N2O3/c1-9-16-14-8-12(19)6-7-13(14)15(20)17(9)10-2-4-11(18)5-3-10/h2-8,18-19H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19941 (3-arylquinazolinone, 1aah | 5-ethoxy-7-hydroxy-3-(...) Show SMILES CCOc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 Show InChI InChI=1S/C16H14N2O4/c1-2-22-14-8-12(20)7-13-15(14)16(21)18(9-17-13)10-3-5-11(19)6-4-10/h3-9,19-20H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19919 (3-arylquinazolinone, 1aak | 3-arylquinazolinone, 1...) Show SMILES COc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 Show InChI InChI=1S/C15H12N2O4/c1-21-13-7-11(19)6-12-14(13)15(20)17(8-16-12)9-2-4-10(18)5-3-9/h2-8,18-19H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19945 (3-arylquinazolinone, 1aal | 7-hydroxy-3-(4-hydroxy...) Show SMILES Oc1ccc(cc1)-n1cnc2cc(O)cc(C#N)c2c1=O Show InChI InChI=1S/C15H9N3O3/c16-7-9-5-12(20)6-13-14(9)15(21)18(8-17-13)10-1-3-11(19)4-2-10/h1-6,8,19-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19946 (3-arylquinazolinone, 1aam | 7-hydroxy-3-(4-hydroxy...) Show SMILES Oc1ccc(cc1)-n1cnc2cc(O)cc(OS(=O)(=O)C(F)(F)F)c2c1=O Show InChI InChI=1S/C15H9F3N2O6S/c16-15(17,18)27(24,25)26-12-6-10(22)5-11-13(12)14(23)20(7-19-11)8-1-3-9(21)4-2-8/h1-7,21-22H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19959 (3-arylquinazolinethione, 1bg | 5-(acetyloxy)-3-[4-...) Show SMILES CC(=O)Oc1ccc(cc1)-n1cnc2cc(OC(C)=O)cc(OC(C)=O)c2c1=S Show InChI InChI=1S/C20H16N2O6S/c1-11(23)26-15-6-4-14(5-7-15)22-10-21-17-8-16(27-12(2)24)9-18(28-13(3)25)19(17)20(22)29/h4-10H,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19960 (3-arylquinazolinethione, 1bh | 7-methoxy-3-(4-meth...) Show SMILES COc1ccc(cc1)-n1cnc2cc(OC)cc(OS(=O)(=O)C(F)(F)F)c2c1=S Show InChI InChI=1S/C17H13F3N2O5S2/c1-25-11-5-3-10(4-6-11)22-9-21-13-7-12(26-2)8-14(15(13)16(22)28)27-29(23,24)17(18,19)20/h3-9H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19961 (3-arylquinazolinethione, 1bi | 5-hydroxy-7-methoxy...) Show SMILES COc1ccc(cc1)-n1cnc2cc(OC)cc(O)c2c1=S Show InChI InChI=1S/C16H14N2O3S/c1-20-11-5-3-10(4-6-11)18-9-17-13-7-12(21-2)8-14(19)15(13)16(18)22/h3-9,19H,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM22430 ((5Z)-6-{4-[2-(dimethylamino)ethoxy]phenyl}-6-(4-hy...) Show SMILES CN(C)CCOc1ccc(cc1)C(=C(\CCCC(O)=O)c1ccccc1)\c1ccc(O)cc1 Show InChI InChI=1S/C28H31NO4/c1-29(2)19-20-33-25-17-13-23(14-18-25)28(22-11-15-24(30)16-12-22)26(9-6-10-27(31)32)21-7-4-3-5-8-21/h3-5,7-8,11-18,30H,6,9-10,19-20H2,1-2H3,(H,31,32)/b28-26-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Binding affinity was measured by a scintillation proximity binding assay using [3H]4-OHT (for ERRgamma) or [3H]estradiol (for ERalpha) as radioligand...				Bioorg Med Chem Lett 16: 821-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.030 BindingDB Entry DOI: 10.7270/Q2WW7FZ7
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM22431 (4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-5-(m...) Show SMILES CNCCC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 Show InChI InChI=1S/C28H34N2O2/c1-29-19-7-10-27(22-8-5-4-6-9-22)28(23-11-15-25(31)16-12-23)24-13-17-26(18-14-24)32-21-20-30(2)3/h4-6,8-9,11-18,29,31H,7,10,19-21H2,1-3H3/b28-27-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Binding affinity was measured by a scintillation proximity binding assay using [3H]4-OHT (for ERRgamma) or [3H]estradiol (for ERalpha) as radioligand...				Bioorg Med Chem Lett 16: 821-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.030 BindingDB Entry DOI: 10.7270/Q2WW7FZ7
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM22432 (4-[(1Z)-5-(dimethylamino)-1-{4-[2-(dimethylamino)e...) Show SMILES CN(C)CCC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 Show InChI InChI=1S/C29H36N2O2/c1-30(2)20-8-11-28(23-9-6-5-7-10-23)29(24-12-16-26(32)17-13-24)25-14-18-27(19-15-25)33-22-21-31(3)4/h5-7,9-10,12-19,32H,8,11,20-22H2,1-4H3/b29-28-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Binding affinity was measured by a scintillation proximity binding assay using [3H]4-OHT (for ERRgamma) or [3H]estradiol (for ERalpha) as radioligand...				Bioorg Med Chem Lett 16: 821-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.030 BindingDB Entry DOI: 10.7270/Q2WW7FZ7
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM19919 (3-arylquinazolinone, 1aak | 3-arylquinazolinone, 1...) Show SMILES COc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 Show InChI InChI=1S/C15H12N2O4/c1-21-13-7-11(19)6-12-14(13)15(20)17(8-16-12)9-2-4-10(18)5-3-9/h2-8,18-19H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	n/a	n/a	n/a	8.0	22
Bristol-Myers Squibb Company					Assay Description Ligand binding was determined using a scintillation proximity assay with streptavidin-coated SPA beads (Amersham) and biotinylated receptor. Receptor...				J Med Chem 49: 2440-55 (2006) Article DOI: 10.1021/jm0509389 BindingDB Entry DOI: 10.7270/Q2WH2N82
					More data for this Ligand-Target Pair