Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KIST) Curated by ChEMBL | Assay Description Inhibition of MAPK15 (unknown origin) | Eur J Med Chem 141: 657-675 (2017) Article DOI: 10.1016/j.ejmech.2017.10.003 BindingDB Entry DOI: 10.7270/Q2CV4M86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of human ERK7 using MBP as substrate by [gamma-33P]-ATP assay | Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ERK7 using MBP as substrate by [gamma-33P]-ATP assay | Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50270298 (CHEMBL4075720) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human ERK7 at 0.123 uM by Hotspot assay | Eur J Med Chem 155: 303-315 (2018) Article DOI: 10.1016/j.ejmech.2018.06.010 BindingDB Entry DOI: 10.7270/Q2668GSP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50548060 (CHEMBL4762609) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human ERK8 (2 to 544 residues) incubated for 5 mins in presence of [gamma33P]ATP by scintillation counting analysis | Citation and Details Article DOI: 10.1039/d0md00203h BindingDB Entry DOI: 10.7270/Q2QJ7MWD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50347388 (CHEMBL1234833) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College London Curated by ChEMBL | Assay Description Inhibition of ERK8 | J Med Chem 53: 8508-22 (2010) Article DOI: 10.1021/jm100732t BindingDB Entry DOI: 10.7270/Q2B858GZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50441090 (CHEMBL2430323 | US9669028, 114 N-(3-(3-methyl-1H-p...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Edinburgh Cancer Research Centre in the Institute of Genetics and Molecular Medicine Curated by ChEMBL | Assay Description Inhibition of human ERK8 in presence of 5 uM ATP | Bioorg Med Chem Lett 23: 5578-85 (2013) Article DOI: 10.1016/j.bmcl.2013.08.046 BindingDB Entry DOI: 10.7270/Q2Q52R2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50509365 (CHEMBL4564337) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway Curated by ChEMBL | Assay Description Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assay | J Med Chem 62: 10167-10181 (2019) Article DOI: 10.1021/acs.jmedchem.9b01006 BindingDB Entry DOI: 10.7270/Q26M3B4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50509369 (CHEMBL4548361) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway Curated by ChEMBL | Assay Description Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assay | J Med Chem 62: 10167-10181 (2019) Article DOI: 10.1021/acs.jmedchem.9b01006 BindingDB Entry DOI: 10.7270/Q26M3B4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50509366 (CHEMBL4555884) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway Curated by ChEMBL | Assay Description Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assay | J Med Chem 62: 10167-10181 (2019) Article DOI: 10.1021/acs.jmedchem.9b01006 BindingDB Entry DOI: 10.7270/Q26M3B4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50509368 (CHEMBL4475097) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway Curated by ChEMBL | Assay Description Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assay | J Med Chem 62: 10167-10181 (2019) Article DOI: 10.1021/acs.jmedchem.9b01006 BindingDB Entry DOI: 10.7270/Q26M3B4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50509367 (CHEMBL4476426) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway Curated by ChEMBL | Assay Description Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assay | J Med Chem 62: 10167-10181 (2019) Article DOI: 10.1021/acs.jmedchem.9b01006 BindingDB Entry DOI: 10.7270/Q26M3B4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50135286 (CHEMBL3745885) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Icahn School of Medicine at Mount Sinai Curated by ChEMBL | Assay Description Inhibition of human ERK7 using MBP as substrate | Bioorg Med Chem 24: 521-44 (2016) Article DOI: 10.1016/j.bmc.2015.11.045 BindingDB Entry DOI: 10.7270/Q24Q7WT8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50509370 (CHEMBL4446434) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
UiT - The Arctic University of Norway Curated by ChEMBL | Assay Description Inhibition of ERK8 (unknown origin) by [33P]-ATP filter binding kinase assay | J Med Chem 62: 10167-10181 (2019) Article DOI: 10.1021/acs.jmedchem.9b01006 BindingDB Entry DOI: 10.7270/Q26M3B4R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 15 (Homo sapiens (Human)) | BDBM50510133 (CHEMBL4446681) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8-fused ERK7 N-terminal domain (M1 to R354 residues) expressed in Sf9 insect c... | Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4 | |||||||||||
More data for this Ligand-Target Pair |