Compile Data Set for Download or QSAR

Found 18 hits of ic50 for UniProtKB: P0A7Y4   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343049 ((1S,3R,4R,5R)-3-[(E)-3-(3,4-Dihydroxy-phenyl)-acry...) Show SMILES COC(=O)[C@]1(O)C[C@@H](O)[C@@H](O)[C@@H](C1)OC(=O)\C=C\c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C17H20O9/c1-25-16(23)17(24)7-12(20)15(22)13(8-17)26-14(21)5-3-9-2-4-10(18)11(19)6-9/h2-6,12-13,15,18-20,22,24H,7-8H2,1H3/b5-3+/t12-,13-,15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343049 ((1S,3R,4R,5R)-3-[(E)-3-(3,4-Dihydroxy-phenyl)-acry...) Show SMILES COC(=O)[C@]1(O)C[C@@H](O)[C@@H](O)[C@@H](C1)OC(=O)\C=C\c1ccc(O)c(O)c1 |r| Show InChI InChI=1S/C17H20O9/c1-25-16(23)17(24)7-12(20)15(22)13(8-17)26-14(21)5-3-9-2-4-10(18)11(19)6-9/h2-6,12-13,15,18-20,22,24H,7-8H2,1H3/b5-3+/t12-,13-,15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343045 ((1R,2R,4S)-p-menthane-1,2,8-triol-1-O-beta-D-gluco...) Show SMILES CC(C)(O)[C@H]1CC[C@@](C)(O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)C1 |r| Show InChI InChI=1S/C16H30O8/c1-15(2,22)8-4-5-16(3,10(18)6-8)24-14-13(21)12(20)11(19)9(7-17)23-14/h8-14,17-22H,4-7H2,1-3H3/t8-,9-,10+,11-,12+,13-,14+,16+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343046 ((4R)-p-menth-1-ene-7,8-diol-7-O-[beta-D-xylopyrano...) Show SMILES CC(C)(O)[C@@H]1CCC(CO[C@H]2O[C@@H](CO[C@H]3OC[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)=CC1 |r,c:31| Show InChI InChI=1S/C21H36O11/c1-21(2,28)11-5-3-10(4-6-11)7-29-20-18(27)16(25)15(24)13(32-20)9-31-19-17(26)14(23)12(22)8-30-19/h3,11-20,22-28H,4-9H2,1-2H3/t11-,12-,13-,14+,15-,16+,17-,18-,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343047 (CHEMBL1770694 | iso-dihydrodendranthemoside A) Show SMILES C[C@H](O)CC[C@@]1(O)[C@@H](C)C[C@@H](CC1(C)C)O[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H36O8/c1-10-7-12(8-18(3,4)19(10,25)6-5-11(2)21)26-17-16(24)15(23)14(22)13(9-20)27-17/h10-17,20-25H,5-9H2,1-4H3/t10-,11-,12-,13-,14-,15+,16-,17-,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50187665 ((-)-epigallocatechin | CHEMBL47386) Show SMILES O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1 |r| Show InChI InChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50269651 (CHEMBL465208 | salidroside) Show SMILES OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343048 (6''-O-galloylsalidroside | CHEMBL1770695) Show SMILES O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OCCc2ccc(O)cc2)[C@@H]1O |r| Show InChI InChI=1S/C21H24O11/c22-12-3-1-10(2-4-12)5-6-30-21-19(28)18(27)17(26)15(32-21)9-31-20(29)11-7-13(23)16(25)14(24)8-11/h1-4,7-8,15,17-19,21-28H,5-6,9H2/t15-,17-,18+,19-,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50241356 (4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphen...) Show SMILES COc1cc(\C=C\CO)cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H24O9/c1-23-10-6-9(4-3-5-18)7-11(24-2)16(10)26-17-15(22)14(21)13(20)12(8-19)25-17/h3-4,6-7,12-15,17-22H,5,8H2,1-2H3/b4-3+/t12-,13-,14+,15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50241356 (4-[(1E)-3-hydroxyprop-1-en-1-yl]-2,6-dimethoxyphen...) Show SMILES COc1cc(\C=C\CO)cc(OC)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H24O9/c1-23-10-6-9(4-3-5-18)7-11(24-2)16(10)26-17-15(22)14(21)13(20)12(8-19)25-17/h3-4,6-7,12-15,17-22H,5,8H2,1-2H3/b4-3+/t12-,13-,14+,15-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343045 ((1R,2R,4S)-p-menthane-1,2,8-triol-1-O-beta-D-gluco...) Show SMILES CC(C)(O)[C@H]1CC[C@@](C)(O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)C1 |r| Show InChI InChI=1S/C16H30O8/c1-15(2,22)8-4-5-16(3,10(18)6-8)24-14-13(21)12(20)11(19)9(7-17)23-14/h8-14,17-22H,4-7H2,1-3H3/t8-,9-,10+,11-,12+,13-,14+,16+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343046 ((4R)-p-menth-1-ene-7,8-diol-7-O-[beta-D-xylopyrano...) Show SMILES CC(C)(O)[C@@H]1CCC(CO[C@H]2O[C@@H](CO[C@H]3OC[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)=CC1 |r,c:31| Show InChI InChI=1S/C21H36O11/c1-21(2,28)11-5-3-10(4-6-11)7-29-20-18(27)16(25)15(24)13(32-20)9-31-19-17(26)14(23)12(22)8-30-19/h3,11-20,22-28H,4-9H2,1-2H3/t11-,12-,13-,14+,15-,16+,17-,18-,19+,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343047 (CHEMBL1770694 | iso-dihydrodendranthemoside A) Show SMILES C[C@H](O)CC[C@@]1(O)[C@@H](C)C[C@@H](CC1(C)C)O[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C19H36O8/c1-10-7-12(8-18(3,4)19(10,25)6-5-11(2)21)26-17-16(24)15(23)14(22)13(9-20)27-17/h10-17,20-25H,5-9H2,1-4H3/t10-,11-,12-,13-,14-,15+,16-,17-,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50187665 ((-)-epigallocatechin | CHEMBL47386) Show SMILES O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1 |r| Show InChI InChI=1S/C15H14O7/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6/h1-4,12,15-21H,5H2/t12-,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50269651 (CHEMBL465208 | salidroside) Show SMILES OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM50343048 (6''-O-galloylsalidroside | CHEMBL1770695) Show SMILES O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(O)c(O)c2)O[C@@H](OCCc2ccc(O)cc2)[C@@H]1O |r| Show InChI InChI=1S/C21H24O11/c22-12-3-1-10(2-4-12)5-6-30-21-19(28)18(27)17(26)15(32-21)9-31-20(29)11-7-13(23)16(25)14(24)8-11/h1-4,7-8,15,17-19,21-28H,5-6,9H2/t15-,17-,18+,19-,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chungnam National University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay				Bioorg Med Chem Lett 21: 2840-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.091 BindingDB Entry DOI: 10.7270/Q2H70G48
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM33963 (vinylogous urea, NSC727448) Show SMILES Cc1sc(NC(=O)c2ccco2)c(C(N)=O)c1C Show InChI InChI=1S/C12H12N2O3S/c1-6-7(2)18-12(9(6)10(13)15)14-11(16)8-4-3-5-17-8/h3-5H,1-2H3,(H2,13,15)(H,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	8.0	20
National Cancer Institute					Assay Description RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...				ACS Chem Biol 3: 635-44 (2008) Article DOI: 10.1021/cb8001039 BindingDB Entry DOI: 10.7270/Q29P300F
					More data for this Ligand-Target Pair
Ribonuclease HI (Escherichia coli (strain K12))	BDBM33045 (2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...) Show SMILES NC(=O)c1c(N)sc2CCCCCc12 Show InChI InChI=1S/C10H14N2OS/c11-9(13)8-6-4-2-1-3-5-7(6)14-10(8)12/h1-5,12H2,(H2,11,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	8.0	20
National Cancer Institute					Assay Description RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...				ACS Chem Biol 3: 635-44 (2008) Article DOI: 10.1021/cb8001039 BindingDB Entry DOI: 10.7270/Q29P300F
					More data for this Ligand-Target Pair