Compile Data Set for Download or QSAR

Found 19 hits of ec50 for UniProtKB: P30557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35861 (phenylpropanoic acid analogue, 5) Show SMILES OC(=O)CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H24N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-9,13-14,16-17H,10-12,15,18H2,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35854 (acrylic acid derivative, 12) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H22N2O3/c28-25(29)10-9-22-8-6-20(17-27-13-12-26-18-27)16-24(22)30-14-11-19-5-7-21-3-1-2-4-23(21)15-19/h1-10,12-13,15-16,18H,11,14,17H2,(H,28,29)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35855 (acrylic acid derivative, 4) Show SMILES OC(=O)\C=C\c1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H22N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-11,13-14,16-17H,12,15,18H2,(H,28,29)/b11-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	12	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35859 (acrylic acid derivative, 16) Show SMILES OC(=O)\C=C\c1ccc(COc2ccccc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C28H24O4/c29-28(30)15-14-24-13-11-22(20-32-26-8-2-1-3-9-26)19-27(24)31-17-16-21-10-12-23-6-4-5-7-25(23)18-21/h1-15,18-19H,16-17,20H2,(H,29,30)/b15-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	130	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35858 (acrylic acid derivative, 15) Show SMILES OC(=O)\C=C\c1ccc(Cc2cccs2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C26H22O3S/c27-26(28)12-11-22-10-8-20(17-24-6-3-15-30-24)18-25(22)29-14-13-19-7-9-21-4-1-2-5-23(21)16-19/h1-12,15-16,18H,13-14,17H2,(H,27,28)/b12-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	150	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35853 (acrylic acid derivative, 11) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCc1cc2ccccc2o1 Show InChI InChI=1S/C23H20N2O4/c26-23(27)8-7-18-6-5-17(15-25-11-10-24-16-25)13-22(18)28-12-9-20-14-19-3-1-2-4-21(19)29-20/h1-8,10-11,13-14,16H,9,12,15H2,(H,26,27)/b8-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	44	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35857 (acrylic acid derivative, 14) Show SMILES OC(=O)\C=C\c1ccc(Cc2ccccc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C28H24O3/c29-28(30)15-14-25-13-11-23(18-21-6-2-1-3-7-21)20-27(25)31-17-16-22-10-12-24-8-4-5-9-26(24)19-22/h1-15,19-20H,16-18H2,(H,29,30)/b15-14+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	130	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35864 (phenylbutanoic acid analogue, 20) Show SMILES OC(=O)CCCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C26H26N2O3/c29-26(30)8-3-7-23-12-10-21(19-28-15-4-14-27-28)18-25(23)31-16-13-20-9-11-22-5-1-2-6-24(22)17-20/h1-2,4-6,9-12,14-15,17-18H,3,7-8,13,16,19H2,(H,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	39	n/a	n/a	n/a	460	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35865 (benzyloxyacetic acid analogue, 21) Show SMILES OC(=O)COCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H24N2O4/c28-25(29)18-30-17-23-9-7-20(16-27-12-3-11-26-27)15-24(23)31-13-10-19-6-8-21-4-1-2-5-22(21)14-19/h1-9,11-12,14-15H,10,13,16-18H2,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	210	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35856 (acrylic acid derivative, 13) Show SMILES OC(=O)\C=C\c1ccc(CN2CCCC2=O)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C26H25NO4/c28-25-6-3-14-27(25)18-20-8-10-22(11-12-26(29)30)24(17-20)31-15-13-19-7-9-21-4-1-2-5-23(21)16-19/h1-2,4-5,7-12,16-17H,3,6,13-15,18H2,(H,29,30)/b12-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	110	n/a	n/a	n/a	580	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35846 (acrylic acid derivative, 3) Show SMILES Cc1c(C)c2OC(C)(CCOc3cc(Cn4ccnc4)ccc3\C=C\C(O)=O)CCc2c(C)c1O Show InChI InChI=1S/C28H32N2O5/c1-18-19(2)27-23(20(3)26(18)33)9-10-28(4,35-27)11-14-34-24-15-21(16-30-13-12-29-17-30)5-6-22(24)7-8-25(31)32/h5-8,12-13,15,17,33H,9-11,14,16H2,1-4H3,(H,31,32)/b8-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	63	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35862 (phenylpropynoic acid analogue, 18) Show SMILES OC(=O)C#Cc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H20N2O3/c28-25(29)11-10-22-9-7-20(18-27-14-3-13-26-27)17-24(22)30-15-12-19-6-8-21-4-1-2-5-23(21)16-19/h1-9,13-14,16-17H,12,15,18H2,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	99	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35860 (acrylic acid derivative, 17) Show SMILES OC(=O)\C=C\c1ccc(OCc2ccccc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C28H24O4/c29-28(30)15-13-24-12-14-26(32-20-22-6-2-1-3-7-22)19-27(24)31-17-16-21-10-11-23-8-4-5-9-25(23)18-21/h1-15,18-19H,16-17,20H2,(H,29,30)/b15-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	850	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35863 (phenoxyacetic acid analogue, 19) Show SMILES OC(=O)COc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C24H22N2O4/c27-24(28)17-30-22-9-7-19(16-26-12-3-11-25-26)15-23(22)29-13-10-18-6-8-20-4-1-2-5-21(20)14-18/h1-9,11-12,14-15H,10,13,16-17H2,(H,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	260	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35851 (acrylic acid derivative, 9) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCCOc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-22(26)10-9-19-8-7-18(16-24-12-11-23-17-24)15-21(19)28-14-4-13-27-20-5-2-1-3-6-20/h1-3,5-12,15,17H,4,13-14,16H2,(H,25,26)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	280	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35849 (acrylic acid derivative, 7) Show SMILES Cc1ccc(\C=C\C(O)=O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1 Show InChI InChI=1S/C25H30O5/c1-15-6-7-19(8-9-22(26)27)21(14-15)29-13-12-25(5)11-10-20-18(4)23(28)16(2)17(3)24(20)30-25/h6-9,14,28H,10-13H2,1-5H3,(H,26,27)/b9-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	940	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35852 (acrylic acid derivative, 10) Show SMILES OC(=O)\C=C\c1ccc(Cn2ccnc2)cc1OCCCCOc1ccccc1 Show InChI InChI=1S/C23H24N2O4/c26-23(27)11-10-20-9-8-19(17-25-13-12-24-18-25)16-22(20)29-15-5-4-14-28-21-6-2-1-3-7-21/h1-3,6-13,16,18H,4-5,14-15,17H2,(H,26,27)/b11-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	220	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35848 (acrylic acid derivative, 6) Show SMILES Cc1c(C)c2OC(C)(CCOc3ccccc3\C=C\C(O)=O)CCc2c(C)c1O Show InChI InChI=1S/C24H28O5/c1-15-16(2)23-19(17(3)22(15)27)11-12-24(4,29-23)13-14-28-20-8-6-5-7-18(20)9-10-21(25)26/h5-10,27H,11-14H2,1-4H3,(H,25,26)/b10-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	530	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM35850 (acrylic acid derivative, 8) Show SMILES COc1ccc(\C=C\C(O)=O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1 Show InChI InChI=1S/C25H30O6/c1-15-16(2)24-20(17(3)23(15)28)10-11-25(4,31-24)12-13-30-21-14-19(29-5)8-6-18(21)7-9-22(26)27/h6-9,14,28H,10-13H2,1-5H3,(H,26,27)/b9-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd					Assay Description Competitive binding studies were conducted using radiolabeled ligands and membrane fractions prepared from Chinese hamster ovary (CHO) cells stably e...				Bioorg Med Chem 17: 6567-82 (2009) Article DOI: 10.1016/j.bmc.2009.08.007 BindingDB Entry DOI: 10.7270/Q23T9FK7
					More data for this Ligand-Target Pair