Compile Data Set for Download or QSAR

Found 338 hits of ec50 for UniProtKB: Q9Y478   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563544 (US11407768, Compound 1) Show SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563546 (US11407768, Compound 3) Show SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563547 (US11407768, Compound 4) Show SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNCc1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565695 (US11407768, Compound 74) Show SMILES OCCOCCNCc1ccc(c(O)c1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565454 (US11407768, Compound 53) Show SMILES OCC(CO)(CO)NCc1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.230	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565696 (US11407768, Compound 75) Show SMILES OCCOCCNC(=O)c1ccc(c(O)c1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563553 (US11407768, Compound 10) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCNc1cccc2c(cccc12)S(O)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563498 ((2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-...) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCc1ccc(cc1)S(O)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.460	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM237992 (US9394285, 75) Show SMILES OCC1(CC1)c1ccc(cc1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O Show InChI InChI=1S/C19H16ClNO3/c20-16-8-17-14(15(9-21-17)18(23)24)7-13(16)11-1-3-12(4-2-11)19(10-22)5-6-19/h1-4,7-9,21-22H,5-6,10H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	7.5	25
Pfizer Inc. US Patent					Assay Description The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...				US Patent US9394285 (2016) BindingDB Entry DOI: 10.7270/Q2DB80Q7
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563556 (US11407768, Compound 14) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCP(O)(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563558 (US11407768, Compound 29) Show SMILES C[N+](C)(C)CCNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.560	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565456 (US11407768, Compound 54) Show SMILES OCC1(CO)CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2nc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.570	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563549 (US11407768, Compound 6) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCCS(O)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.620	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565561 (US11407768, Compound 71) Show SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.630	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563501 ((2S)-2-amino-3-(4-(2- amino-6-((R)-2,2,2- trifluor...) Show SMILES OC(CNCc1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.630	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563503 ((2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-...) Show SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.650	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase subunit beta-1 (Homo sapiens (Human))	BDBM50195477 (CHEMBL3979403) Show SMILES COc1cc(on1)C(O)=C1C(=O)Nc2cc(Cl)c(cc12)-c1ccc2n(C)ccc2c1 Show InChI InChI=1S/C22H16ClN3O4/c1-26-6-5-12-7-11(3-4-17(12)26)13-8-14-16(9-15(13)23)24-22(28)20(14)21(27)18-10-19(29-2)25-30-18/h3-10,27H,1-2H3,(H,24,28)/b21-20+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.700	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of recombinant human His-tagged AMPK alpha2 (2 to 552 residues)/beta1 (2 to 270 residues)/gamma2 (2 to 569 residues) expressed in baculovi...				Bioorg Med Chem Lett 26: 5139-5148 (2016) Article DOI: 10.1016/j.bmcl.2016.09.065 BindingDB Entry DOI: 10.7270/Q25M67PH
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565449 (US11407768, Compound 51) Show SMILES OCCN1CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2nc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.720	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563505 ((S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2- (5,6-dihy...) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2cc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCC[N+]12CCN(CC1)CC2 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.760	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565498 (US11407768, Compound 65) Show SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNCc1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.770	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565503 (US11407768, Compound 66) Show SMILES OCC1(CO)CN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565452 (US11407768, Compound 52) Show SMILES OCC1(CO)CN(Cc2ccc(cc2)-c2ccc(cc2)-c2nc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.810	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563563 (US11407768, Compound 36) Show SMILES OCC(CO)(CO)NCc1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.840	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565483 (US11407768, Compound 60) Show SMILES OCC1(CO)CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.850	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565483 (US11407768, Compound 60) Show SMILES OCC1(CO)CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.850	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563560 (US11407768, Compound 31) Show SMILES OCCOCCNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.850	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563548 (US11407768, Compound 5) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCS(O)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.860	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565476 (US11407768, Compound 57) Show SMILES CN1CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.890	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565506 (US11407768, Compound 67) Show SMILES NCC1CN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.930	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565474 (US11407768, Compound 56) Show SMILES OCCN1CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)CC1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.930	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565478 (US11407768, Compound 58) Show SMILES OCCOCCNCc1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.930	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563562 (US11407768, Compound 33) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2cc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCCC[N+]12CCN(CC1)CC2 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.960	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM50195478 (CHEMBL3959081) Show SMILES Cc1ccc(Oc2nc3nc(c(Cl)cc3[nH]2)-c2ccc(cc2)N2CCCC2)cc1C(O)=O Show InChI InChI=1S/C24H21ClN4O3/c1-14-4-9-17(12-18(14)23(30)31)32-24-26-20-13-19(25)21(27-22(20)28-24)15-5-7-16(8-6-15)29-10-2-3-11-29/h4-9,12-13H,2-3,10-11H2,1H3,(H,30,31)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of full length human recombinant AMPK alpha1/beta1/gamma1 expressed in baculovirus infected sf21 cells using 5'-FAM-SAMS peptide substrate...				Bioorg Med Chem Lett 26: 5139-5148 (2016) Article DOI: 10.1016/j.bmcl.2016.09.065 BindingDB Entry DOI: 10.7270/Q25M67PH
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565481 (US11407768, Compound 59) Show SMILES O[C@@H]1CCN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.04	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563566 (US11407768, Compound 40) Show SMILES OCC(CO)NCc1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.08	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565494 (US11407768, Compound 63) Show SMILES OCC1CN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.09	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563568 (US11407768, Compound 48) Show SMILES CN(CCOCCO)C(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.16	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM50195538 (CHEMBL3898977) Show SMILES Cc1ccc(Oc2nc3cc(c(Cl)cc3[nH]2)-c2ccc(cc2)N2CCOCC2)cc1P(O)(O)=O Show InChI InChI=1S/C24H23ClN3O5P/c1-15-2-7-18(12-23(15)34(29,30)31)33-24-26-21-13-19(20(25)14-22(21)27-24)16-3-5-17(6-4-16)28-8-10-32-11-9-28/h2-7,12-14H,8-11H2,1H3,(H,26,27)(H2,29,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of full length human recombinant AMPK alpha1/beta1/gamma1 expressed in baculovirus infected sf21 cells using SAMS peptide substrate after ...				Bioorg Med Chem Lett 26: 5139-5148 (2016) Article DOI: 10.1016/j.bmcl.2016.09.065 BindingDB Entry DOI: 10.7270/Q25M67PH
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563550 (US11407768, Compound 7) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)C(=O)NCC(CS(O)(=O)=O)c1ccc(Cl)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.22	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM237984 (US9394285, 67) Show SMILES OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc(cc1)-c1ccccc1O Show InChI InChI=1S/C21H14ClNO3/c22-18-10-19-16(17(11-23-19)21(25)26)9-15(18)13-7-5-12(6-8-13)14-3-1-2-4-20(14)24/h1-11,23-24H,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphoryl...				J Med Chem 59: 8068-81 (2016) Article DOI: 10.1021/acs.jmedchem.6b00866 BindingDB Entry DOI: 10.7270/Q2PZ5BRC
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565492 (US11407768, Compound 62) Show SMILES CN(CCOCCO)Cc1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565694 (US11407768, Compound 73) Show SMILES CC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)c1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.33	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565486 (US11407768, Compound 61) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2cc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(CN2C[C@H](O)[C@H](O)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.36	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565693 (US11407768, Compound 72) Show SMILES CN(CCOCCO)S(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.38	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565496 (US11407768, Compound 64) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2cc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(CN2C[C@H](O)[C@@H](O)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563545 (US11407768, Compound 2) Show SMILES O[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)Oc1nc2nc(c(Cl)cc2[nH]1)-c1ccc(cc1)-c1ccc(cc1)P(O)(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.40	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565446 (US11407768, Compound 50) Show SMILES OCCOCC1CN(Cc2ccc(cc2)-c2ccc(cc2)-c2cc3nc(O[C@@H]4CO[C@@H]5[C@H](O)CO[C@H]45)[nH]c3cc2Cl)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.46	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM565530 (US11407768, Compound 70) Show SMILES OCCOCCNS(=O)(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.51	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM563552 (US11407768, Compound 9) Show SMILES NC(=O)CN(CCS(O)(=O)=O)C(=O)c1ccc(cc1)-c1ccc(cc1)-c1nc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.61	n/a	n/a	n/a	n/a
TBA					Assay Description Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KD223Z
					More data for this Ligand-Target Pair
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1 (Homo sapiens (Human))	BDBM237962 (US9394285, 43) Show SMILES OC(=O)c1c[nH]c2cc(Cl)c(cc12)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H14ClNO2/c22-19-11-20-17(18(12-23-20)21(24)25)10-16(19)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-12,23H,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.70	n/a	n/a	7.5	25
Pfizer Inc. US Patent					Assay Description The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...				US Patent US9394285 (2016) BindingDB Entry DOI: 10.7270/Q2DB80Q7
					More data for this Ligand-Target Pair

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