Compile Data Set for Download or QSAR

Found 153 hits of ic50 for UniProtKB: Q9UEE5   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50585203 (CHEMBL5085430) Show SMILES Brc1cnc(Nc2cccc(NC(=O)N3CCCC3)c2)nc1NCCCNC(=O)C1CCC1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00440 BindingDB Entry DOI: 10.7270/Q27S7SND
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50274640 (CHEMBL4126445) Show SMILES C[C@@H](C1CC1)N1Cc2cc(cc(C)c2C1=O)-c1sc(NC(C)=O)nc1C |r| Show InChI InChI=1S/C20H23N3O2S/c1-10-7-15(18-11(2)21-20(26-18)22-13(4)24)8-16-9-23(19(25)17(10)16)12(3)14-5-6-14/h7-8,12,14H,5-6,9H2,1-4H3,(H,21,22,24)/t12-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaron-Beijing Co., Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human full length GST-tagged DRAK1 expressed in baculovirus expression system				J Med Chem 61: 5435-5441 (2018) Article DOI: 10.1021/acs.jmedchem.8b00447 BindingDB Entry DOI: 10.7270/Q27M0BFZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441855 (US10647686, Example (3)) Show SMILES CC(C)c1ccc(Nc2ncc(Cl)c(NCCCN)n2)cc1 Show InChI InChI=1S/C16H22ClN5/c1-11(2)12-4-6-13(7-5-12)21-16-20-10-14(17)15(22-16)19-9-3-8-18/h4-7,10-11H,3,8-9,18H2,1-2H3,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50166076 (CHEMBL3799585) Show SMILES CCCC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1 Show InChI InChI=1S/C20H18N4O3/c1-2-5-16(25)21-11-8-9-15-13(10-11)17(20(26)23-15)19-18(24-27)12-6-3-4-7-14(12)22-19/h3-4,6-10,22,27H,2,5H2,1H3,(H,21,25)(H,23,26)/b19-17-,24-18+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK1 (unknown origin)				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50154342 (CHEMBL3774448) Show SMILES O=C1NC(=S)S\C1=C/c1ccc2ncccc2c1 Show InChI InChI=1S/C13H8N2OS2/c16-12-11(18-13(17)15-12)7-8-3-4-10-9(6-8)2-1-5-14-10/h1-7H,(H,15,16,17)/b11-7-	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Saarland University Curated by ChEMBL					Assay Description Inhibition of STK17A (unknown origin)				Eur J Med Chem 112: 209-16 (2016) Article DOI: 10.1016/j.ejmech.2016.02.017 BindingDB Entry DOI: 10.7270/Q2GF0WC4
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441866 (US10647686, Example (13)) Show SMILES NCCCNc1nc(Nc2ccc(cc2)S(=O)(=O)c2ccc(cc2)[N+]([O-])=O)ncc1Cl Show InChI InChI=1S/C19H19ClN6O4S/c20-17-12-23-19(25-18(17)22-11-1-10-21)24-13-2-6-15(7-3-13)31(29,30)16-8-4-14(5-9-16)26(27)28/h2-9,12H,1,10-11,21H2,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50520157 (CHEMBL4436188) Show SMILES C[C@@H](N1CCN(CC1)C(=O)CC(F)(F)F)c1ccnc(Nc2nc3ccc(cc3[nH]2)-c2cnn(CC3CCC3)c2)c1 |r| Show InChI InChI=1S/C29H33F3N8O/c1-19(38-9-11-39(12-10-38)27(41)15-29(30,31)32)21-7-8-33-26(14-21)37-28-35-24-6-5-22(13-25(24)36-28)23-16-34-40(18-23)17-20-3-2-4-20/h5-8,13-14,16,18-20H,2-4,9-12,15,17H2,1H3,(H2,33,35,36,37)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Inhibition of wild-type human partial length DRAK1 (R32 to E363 residues) expressed in bacterial expression system by Kinomescan method				J Med Chem 63: 601-612 (2020) Article DOI: 10.1021/acs.jmedchem.9b01460 BindingDB Entry DOI: 10.7270/Q2CN7795
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50606011 (CHEMBL5191892) Show SMILES C[C@H](NC(=O)c1ccc-2cc1OCCOCCNc1ccn3ncc-2c3n1)c1ccncc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00173 BindingDB Entry DOI: 10.7270/Q2NC6587
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441876 (US10647686, Example (23)) Show SMILES NCCCNc1nc(Nc2ccc3CCCCc3c2)ncc1Cl Show InChI InChI=1S/C17H22ClN5/c18-15-11-21-17(23-16(15)20-9-3-8-19)22-14-7-6-12-4-1-2-5-13(12)10-14/h6-7,10-11H,1-5,8-9,19H2,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441873 (US10647686, Example (20)) Show SMILES NCCCNc1nc(Nc2ccc3OCOc3c2)ncc1Cl Show InChI InChI=1S/C14H16ClN5O2/c15-10-7-18-14(20-13(10)17-5-1-4-16)19-9-2-3-11-12(6-9)22-8-21-11/h2-3,6-7H,1,4-5,8,16H2,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441862 (US10647686, Example (9)) Show SMILES NCCCNc1nc(Nc2ccc(F)cc2)ncc1Cl Show InChI InChI=1S/C13H15ClFN5/c14-11-8-18-13(20-12(11)17-7-1-6-16)19-10-4-2-9(15)3-5-10/h2-5,8H,1,6-7,16H2,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441882 (US10647686, Example (26)) Show SMILES NCCCNc1nc(Nc2ccc(cc2)C2CCNCC2)ncc1Cl Show InChI InChI=1S/C18H25ClN6/c19-16-12-23-18(25-17(16)22-9-1-8-20)24-15-4-2-13(3-5-15)14-6-10-21-11-7-14/h2-5,12,14,21H,1,6-11,20H2,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441878 (US10647686, Example (24)) Show SMILES NCCCNc1nc(Nc2ccc3C(=O)CCCc3c2)ncc1Cl Show InChI InChI=1S/C17H20ClN5O/c18-14-10-21-17(23-16(14)20-8-2-7-19)22-12-5-6-13-11(9-12)3-1-4-15(13)24/h5-6,9-10H,1-4,7-8,19H2,(H2,20,21,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50166251 (CHEMBL3799389) Show SMILES O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(NC(=O)C3CC3)cc12 Show InChI InChI=1S/C20H16N4O3/c25-19(10-5-6-10)21-11-7-8-15-13(9-11)16(20(26)23-15)18-17(24-27)12-3-1-2-4-14(12)22-18/h1-4,7-10,22,27H,5-6H2,(H,21,25)(H,23,26)/b18-16-,24-17+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK1 (unknown origin)				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441874 (US10647686, Example (21)) Show SMILES NCCCNc1nc(Nc2ccc3CCCc3c2)ncc1Cl Show InChI InChI=1S/C16H20ClN5/c17-14-10-20-16(22-15(14)19-8-2-7-18)21-13-6-5-11-3-1-4-12(11)9-13/h5-6,9-10H,1-4,7-8,18H2,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441881 (US10647686, Example (25)) Show SMILES NCCCNc1nc(Nc2ccc(cc2)N2CCNCC2)ncc1Cl Show InChI InChI=1S/C17H24ClN7/c18-15-12-22-17(24-16(15)21-7-1-6-19)23-13-2-4-14(5-3-13)25-10-8-20-9-11-25/h2-5,12,20H,1,6-11,19H2,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441872 (US10647686, Example (19) | US10647686, Example 19) Show SMILES Cc1cnc(Nc2ccc(Cl)cc2)nc1NCCCN Show InChI InChI=1S/C14H18ClN5/c1-10-9-18-14(20-13(10)17-8-2-7-16)19-12-5-3-11(15)4-6-12/h3-6,9H,2,7-8,16H2,1H3,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441872 (US10647686, Example (19) | US10647686, Example 19) Show SMILES Cc1cnc(Nc2ccc(Cl)cc2)nc1NCCCN Show InChI InChI=1S/C14H18ClN5/c1-10-9-18-14(20-13(10)17-8-2-7-16)19-12-5-3-11(15)4-6-12/h3-6,9H,2,7-8,16H2,1H3,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441870 (US10647686, Example (17)) Show SMILES NCCCNc1nc(Nc2ccc(Br)cc2)ncc1Cl Show InChI InChI=1S/C13H15BrClN5/c14-9-2-4-10(5-3-9)19-13-18-8-11(15)12(20-13)17-7-1-6-16/h2-5,8H,1,6-7,16H2,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441872 (US10647686, Example (19) | US10647686, Example 19) Show SMILES Cc1cnc(Nc2ccc(Cl)cc2)nc1NCCCN Show InChI InChI=1S/C14H18ClN5/c1-10-9-18-14(20-13(10)17-8-2-7-16)19-12-5-3-11(15)4-6-12/h3-6,9H,2,7-8,16H2,1H3,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441858 (US10647686, Example (6)) Show SMILES Cc1ccc(Nc2ncc(Cl)c(NCCCN)n2)cc1Cl Show InChI InChI=1S/C14H17Cl2N5/c1-9-3-4-10(7-11(9)15)20-14-19-8-12(16)13(21-14)18-6-2-5-17/h3-4,7-8H,2,5-6,17H2,1H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50166260 (CHEMBL3799505) Show SMILES CC(C)(C)CC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1 Show InChI InChI=1S/C22H22N4O3/c1-22(2,3)11-17(27)23-12-8-9-16-14(10-12)18(21(28)25-16)20-19(26-29)13-6-4-5-7-15(13)24-20/h4-10,24,29H,11H2,1-3H3,(H,23,27)(H,25,28)/b20-18-,26-19+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK1 (unknown origin)				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441875 (US10647686, Example (22)) Show SMILES NCCCNc1nc(Nc2ccc3OCCOc3c2)ncc1Cl Show InChI InChI=1S/C15H18ClN5O2/c16-11-9-19-15(21-14(11)18-5-1-4-17)20-10-2-3-12-13(8-10)23-7-6-22-12/h2-3,8-9H,1,4-7,17H2,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50166271 (CHEMBL3798563) Show SMILES O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(NC(=O)c3cc(cc(c3)[N+]([O-])=O)[N+]([O-])=O)cc12 Show InChI InChI=1S/C23H14N6O7/c30-22(11-7-13(28(33)34)10-14(8-11)29(35)36)24-12-5-6-18-16(9-12)19(23(31)26-18)21-20(27-32)15-3-1-2-4-17(15)25-21/h1-10,25,32H,(H,24,30)(H,26,31)/b21-19-,27-20+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK1 (unknown origin)				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50520152 (CHEMBL4594167 | US10894784, Example 150.02) Show SMILES CNc1cc(ncn1)-c1ccc2nc(Nc3cc(CN4CCN(CC4)C(=O)CC(F)(F)F)ccn3)[nH]c2c1 Show InChI InChI=1S/C25H26F3N9O/c1-29-21-12-19(31-15-32-21)17-2-3-18-20(11-17)34-24(33-18)35-22-10-16(4-5-30-22)14-36-6-8-37(9-7-36)23(38)13-25(26,27)28/h2-5,10-12,15H,6-9,13-14H2,1H3,(H,29,31,32)(H2,30,33,34,35)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Inhibition of wild-type human partial length DRAK1 (R32 to E363 residues) expressed in bacterial expression system by Kinomescan method				J Med Chem 63: 601-612 (2020) Article DOI: 10.1021/acs.jmedchem.9b01460 BindingDB Entry DOI: 10.7270/Q2CN7795
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441863 (US10647686, Example (10)) Show SMILES NCCCNc1nc(Nc2ccc(Oc3ccccc3)cc2)ncc1Cl Show InChI InChI=1S/C19H20ClN5O/c20-17-13-23-19(25-18(17)22-12-4-11-21)24-14-7-9-16(10-8-14)26-15-5-2-1-3-6-15/h1-3,5-10,13H,4,11-12,21H2,(H2,22,23,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441854 (US10647686, Example (2)) Show SMILES NCCCNc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1Cl Show InChI InChI=1S/C13H14Cl3N5/c14-8-4-9(15)6-10(5-8)20-13-19-7-11(16)12(21-13)18-3-1-2-17/h4-7H,1-3,17H2,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441868 (US10647686, Example (15)) Show SMILES NCCCNc1nc(Nc2ccc(F)c(c2)C(F)(F)F)ncc1Cl Show InChI InChI=1S/C14H14ClF4N5/c15-10-7-22-13(24-12(10)21-5-1-4-20)23-8-2-3-11(16)9(6-8)14(17,18)19/h2-3,6-7H,1,4-5,20H2,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441904 (US10647686, Comparative Example 6) Show SMILES NCCCNc1nc(Nc2ccc(Cl)cc2)ncc1Br Show InChI InChI=1S/C13H15BrClN5/c14-11-8-18-13(20-12(11)17-7-1-6-16)19-10-4-2-9(15)3-5-10/h2-5,8H,1,6-7,16H2,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441904 (US10647686, Comparative Example 6) Show SMILES NCCCNc1nc(Nc2ccc(Cl)cc2)ncc1Br Show InChI InChI=1S/C13H15BrClN5/c14-11-8-18-13(20-12(11)17-7-1-6-16)19-10-4-2-9(15)3-5-10/h2-5,8H,1,6-7,16H2,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50520150 (CHEMBL4566796) Show SMILES COCc1cc(ncn1)-c1ccc2nc(Nc3cc(ccn3)[C@@H](C)N3CCN(CC3)C(=O)CC(F)(F)F)[nH]c2c1 |r| Show InChI InChI=1S/C27H29F3N8O2/c1-17(37-7-9-38(10-8-37)25(39)14-27(28,29)30)18-5-6-31-24(12-18)36-26-34-21-4-3-19(11-23(21)35-26)22-13-20(15-40-2)32-16-33-22/h3-6,11-13,16-17H,7-10,14-15H2,1-2H3,(H2,31,34,35,36)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Inhibition of wild-type human partial length DRAK1 (R32 to E363 residues) expressed in bacterial expression system by Kinomescan method				J Med Chem 63: 601-612 (2020) Article DOI: 10.1021/acs.jmedchem.9b01460 BindingDB Entry DOI: 10.7270/Q2CN7795
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	30.4	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human DRAK1 using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441898 (US10647686, Example (41)) Show SMILES NCCCCNc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1Cl Show InChI InChI=1S/C14H16Cl3N5/c15-9-5-10(16)7-11(6-9)21-14-20-8-12(17)13(22-14)19-4-2-1-3-18/h5-8H,1-4,18H2,(H2,19,20,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50606014 (CHEMBL5193635) Show SMILES CC(NC(=O)c1ccc-2cc1OCCOCCNc1ccn3ncc-2c3n1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00173 BindingDB Entry DOI: 10.7270/Q2NC6587
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	31.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human DRAK1 using KKLNRTLSFAEPG as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50166077 (CHEMBL513703) Show SMILES CC(C)(C)C(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1 Show InChI InChI=1S/C21H20N4O3/c1-21(2,3)20(27)22-11-8-9-15-13(10-11)16(19(26)24-15)18-17(25-28)12-6-4-5-7-14(12)23-18/h4-10,23,28H,1-3H3,(H,22,27)(H,24,26)/b18-16-,25-17+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK1 (unknown origin)				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441905 (US10647686, Example 1) Show SMILES CC(C)(C)OC(=O)NCCCNc1nc(Cl)ncc1Cl Show InChI InChI=1S/C12H18Cl2N4O2/c1-12(2,3)20-11(19)16-6-4-5-15-9-8(13)7-17-10(14)18-9/h7H,4-6H2,1-3H3,(H,16,19)(H,15,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441869 (US10647686, Example (16)) Show SMILES NCCCNc1nc(Nc2ccc(Br)c(c2)C(F)(F)F)ncc1Cl Show InChI InChI=1S/C14H14BrClF3N5/c15-10-3-2-8(6-9(10)14(17,18)19)23-13-22-7-11(16)12(24-13)21-5-1-4-20/h2-3,6-7H,1,4-5,20H2,(H2,21,22,23,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441895 (US10647686, Example (38)) Show SMILES Cc1cnc(Nc2ccc(F)c(Cl)c2)nc1NCCCN Show InChI InChI=1S/C14H17ClFN5/c1-9-8-19-14(21-13(9)18-6-2-5-17)20-10-3-4-12(16)11(15)7-10/h3-4,7-8H,2,5-6,17H2,1H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441871 (US10647686, Example (18)) Show SMILES COc1ccc(Nc2ncc(Cl)c(NCCCN)n2)cc1Cl Show InChI InChI=1S/C14H17Cl2N5O/c1-22-12-4-3-9(7-10(12)15)20-14-19-8-11(16)13(21-14)18-6-2-5-17/h3-4,7-8H,2,5-6,17H2,1H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441867 (US10647686, Example (14)) Show SMILES Cc1ccc(Nc2ncc(Cl)c(NCCCN)n2)cc1C Show InChI InChI=1S/C15H20ClN5/c1-10-4-5-12(8-11(10)2)20-15-19-9-13(16)14(21-15)18-7-3-6-17/h4-5,8-9H,3,6-7,17H2,1-2H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441905 (US10647686, Example 1) Show SMILES CC(C)(C)OC(=O)NCCCNc1nc(Cl)ncc1Cl Show InChI InChI=1S/C12H18Cl2N4O2/c1-12(2,3)20-11(19)16-6-4-5-15-9-8(13)7-17-10(14)18-9/h7H,4-6H2,1-3H3,(H,16,19)(H,15,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441853 (US10647686, Example (1)) Show SMILES NCCCNc1nc(Nc2ccc(Cl)cc2)ncc1Cl Show InChI InChI=1S/C13H15Cl2N5/c14-9-2-4-10(5-3-9)19-13-18-8-11(15)12(20-13)17-7-1-6-16/h2-5,8H,1,6-7,16H2,(H2,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50111572 (CHEMBL3605057) Show SMILES O=C(NCCCNc1nc(Nc2cccc(CN3CCOCC3)c2)ncc1C1CC1)C1CCC1 Show InChI InChI=1S/C26H36N6O2/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32/h1,4,7,16-17,20-21H,2-3,5-6,8-15,18H2,(H,28,33)(H2,27,29,30,31)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of tracer K9 from NLuc fused DRAK1 (unknown origin) expressed in HEK293 cells by NanoBRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00440 BindingDB Entry DOI: 10.7270/Q27S7SND
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441864 (US10647686, Example (11)) Show SMILES CCc1ccc(Nc2ncc(Cl)c(NCCCN)n2)cc1 Show InChI InChI=1S/C15H20ClN5/c1-2-11-4-6-12(7-5-11)20-15-19-10-13(16)14(21-15)18-9-3-8-17/h4-7,10H,2-3,8-9,17H2,1H3,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441897 (US10647686, Example (40) | US10647686, Example 40) Show SMILES NCCCCNc1nc(Nc2ccc(Cl)cc2)ncc1Cl Show InChI InChI=1S/C14H17Cl2N5/c15-10-3-5-11(6-4-10)20-14-19-9-12(16)13(21-14)18-8-2-1-7-17/h3-6,9H,1-2,7-8,17H2,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM441897 (US10647686, Example (40) | US10647686, Example 40) Show SMILES NCCCCNc1nc(Nc2ccc(Cl)cc2)ncc1Cl Show InChI InChI=1S/C14H17Cl2N5/c15-10-3-5-11(6-4-10)20-14-19-9-12(16)13(21-14)18-8-2-1-7-17/h3-6,9H,1-2,7-8,17H2,(H2,18,19,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY US Patent					Assay Description To measure the DRAK1 and DRAK2 activity, the substrate MRCL3 peptide and ATP were mixed with the enzymes. After an appropriate period of time, the re...				US Patent US10647686 (2020) BindingDB Entry DOI: 10.7270/Q2MS3WSB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50606012 (CHEMBL5087558) Show SMILES CC(C)(C)NC(=O)c1ccc-2cc1OCCOCCNc1ccn3ncc-2c3n1 Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00173 BindingDB Entry DOI: 10.7270/Q2NC6587
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM50166121 (CHEMBL3797480) Show SMILES CCCCC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1 Show InChI InChI=1S/C21H20N4O3/c1-2-3-8-17(26)22-12-9-10-16-14(11-12)18(21(27)24-16)20-19(25-28)13-6-4-5-7-15(13)23-20/h4-7,9-11,23,28H,2-3,8H2,1H3,(H,22,26)(H,24,27)/b20-18-,25-19+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of DRAK1 (unknown origin)				Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 17A (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00173 BindingDB Entry DOI: 10.7270/Q2NC6587
					More data for this Ligand-Target Pair

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