Found 6 hits of ki data for polymerid = 4676 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50416570
(CHEMBL1215819)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C127H201N31O35/c1-11-72(8)104(157-114(179)85(44-26-32-56-133)145-124(189)103(71(6)7)155-112(177)83(42-24-30-54-131)140-108(173)80(39-21-27-51-128)138-99(166)65-136-107(172)94(66-159)152-106(171)73(9)137-126(191)105(74(10)162)158-120(185)90(60-78-45-47-79(163)48-46-78)148-116(181)88(139-98(165)64-134)58-75-33-15-12-16-34-75)125(190)154-96(68-161)121(186)142-81(40-22-28-52-129)109(174)143-86(49-50-100(167)168)111(176)153-95(67-160)122(187)146-87(57-69(2)3)115(180)150-92(63-101(169)170)119(184)141-84(43-25-31-55-132)113(178)156-102(70(4)5)123(188)144-82(41-23-29-53-130)110(175)149-91(62-97(135)164)118(183)147-89(59-76-35-17-13-18-36-76)117(182)151-93(127(192)193)61-77-37-19-14-20-38-77/h12-20,33-38,45-48,69-74,80-96,102-105,159-163H,11,21-32,39-44,49-68,128-134H2,1-10H3,(H2,135,164)(H,136,172)(H,137,191)(H,138,166)(H,139,165)(H,140,173)(H,141,184)(H,142,186)(H,143,174)(H,144,188)(H,145,189)(H,146,187)(H,147,183)(H,148,181)(H,149,175)(H,150,180)(H,151,182)(H,152,171)(H,153,176)(H,154,190)(H,155,177)(H,156,178)(H,157,179)(H,158,185)(H,167,168)(H,169,170)(H,192,193)/t72-,73-,74+,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,102-,103-,104-,105-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique& Universite de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p... |
J Med Chem 53: 5782-91 (2010)
Article DOI: 10.1021/jm1002974
BindingDB Entry DOI: 10.7270/Q2NG4RV5 |
More data for this
Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50416568
(CHEMBL1215817)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C121H201N33O34/c1-13-68(10)98(153-108(174)79(41-25-31-49-127)141-118(184)97(67(8)9)151-106(172)77(39-23-29-47-125)136-102(168)74(36-20-26-44-122)134-93(161)59-131-101(167)88(60-155)148-100(166)69(11)133-120(186)99(70(12)158)154-114(180)84(54-73-58-130-63-132-73)144-111(177)83(135-92(160)57-128)52-71-32-16-14-17-33-71)119(185)150-90(62-157)115(181)138-75(37-21-27-45-123)103(169)139-80(42-43-94(162)163)105(171)149-89(61-156)116(182)143-81(50-64(2)3)109(175)146-86(56-95(164)165)113(179)137-78(40-24-30-48-126)107(173)152-96(66(6)7)117(183)140-76(38-22-28-46-124)104(170)145-85(55-91(129)159)112(178)142-82(51-65(4)5)110(176)147-87(121(187)188)53-72-34-18-15-19-35-72/h14-19,32-35,58,63-70,74-90,96-99,155-158H,13,20-31,36-57,59-62,122-128H2,1-12H3,(H2,129,159)(H,130,132)(H,131,167)(H,133,186)(H,134,161)(H,135,160)(H,136,168)(H,137,179)(H,138,181)(H,139,169)(H,140,183)(H,141,184)(H,142,178)(H,143,182)(H,144,177)(H,145,170)(H,146,175)(H,147,176)(H,148,166)(H,149,171)(H,150,185)(H,151,172)(H,152,173)(H,153,174)(H,154,180)(H,162,163)(H,164,165)(H,187,188)/t68-,69-,70+,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,96-,97-,98-,99-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique& Universite de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p... |
J Med Chem 53: 5782-91 (2010)
Article DOI: 10.1021/jm1002974
BindingDB Entry DOI: 10.7270/Q2NG4RV5 |
More data for this
Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50416569
(CHEMBL1215818)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C124H199N33O33/c1-12-70(8)101(156-112(177)83(45-27-33-53-130)145-121(186)100(69(6)7)154-110(175)81(43-25-31-51-128)141-106(171)78(40-22-28-48-125)138-96(163)63-134-105(170)92(64-158)152-104(169)72(10)137-123(188)102(73(11)160)157-118(183)88(58-77-62-133-66-135-77)148-114(179)86(139-95(162)61-131)55-74-34-16-13-17-35-74)122(187)136-71(9)103(168)140-79(41-23-29-49-126)107(172)143-84(46-47-97(164)165)109(174)153-93(65-159)119(184)146-85(54-67(2)3)113(178)150-90(60-98(166)167)117(182)142-82(44-26-32-52-129)111(176)155-99(68(4)5)120(185)144-80(42-24-30-50-127)108(173)149-89(59-94(132)161)116(181)147-87(56-75-36-18-14-19-37-75)115(180)151-91(124(189)190)57-76-38-20-15-21-39-76/h13-21,34-39,62,66-73,78-93,99-102,158-160H,12,22-33,40-61,63-65,125-131H2,1-11H3,(H2,132,161)(H,133,135)(H,134,170)(H,136,187)(H,137,188)(H,138,163)(H,139,162)(H,140,168)(H,141,171)(H,142,182)(H,143,172)(H,144,185)(H,145,186)(H,146,184)(H,147,181)(H,148,179)(H,149,173)(H,150,178)(H,151,180)(H,152,169)(H,153,174)(H,154,175)(H,155,176)(H,156,177)(H,157,183)(H,164,165)(H,166,167)(H,189,190)/t70-,71-,72-,73+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,99-,100-,101-,102-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique& Universite de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p... |
J Med Chem 53: 5782-91 (2010)
Article DOI: 10.1021/jm1002974
BindingDB Entry DOI: 10.7270/Q2NG4RV5 |
More data for this
Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50416566
(CHEMBL1215815)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C124H203N31O34/c1-14-70(10)101(154-112(176)83(42-26-32-54-130)143-121(185)100(69(8)9)152-110(174)81(40-24-30-52-128)139-106(170)78(37-21-27-49-125)136-96(162)63-133-105(169)92(64-156)150-104(168)72(12)135-123(187)102(73(13)158)155-118(182)88(58-76-43-45-77(159)46-44-76)146-115(179)87(137-95(161)62-131)57-74-33-17-15-18-34-74)122(186)134-71(11)103(167)138-79(38-22-28-50-126)107(171)141-84(47-48-97(163)164)109(173)151-93(65-157)119(183)145-85(55-66(2)3)113(177)148-90(61-98(165)166)117(181)140-82(41-25-31-53-129)111(175)153-99(68(6)7)120(184)142-80(39-23-29-51-127)108(172)147-89(60-94(132)160)116(180)144-86(56-67(4)5)114(178)149-91(124(188)189)59-75-35-19-16-20-36-75/h15-20,33-36,43-46,66-73,78-93,99-102,156-159H,14,21-32,37-42,47-65,125-131H2,1-13H3,(H2,132,160)(H,133,169)(H,134,186)(H,135,187)(H,136,162)(H,137,161)(H,138,167)(H,139,170)(H,140,181)(H,141,171)(H,142,184)(H,143,185)(H,144,180)(H,145,183)(H,146,179)(H,147,172)(H,148,177)(H,149,178)(H,150,168)(H,151,173)(H,152,174)(H,153,175)(H,154,176)(H,155,182)(H,163,164)(H,165,166)(H,188,189)/t70-,71-,72-,73+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,99-,100-,101-,102-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique& Universite de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p... |
J Med Chem 53: 5782-91 (2010)
Article DOI: 10.1021/jm1002974
BindingDB Entry DOI: 10.7270/Q2NG4RV5 |
More data for this
Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50416564
(CHEMBL1215813)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C121H201N33O33/c1-14-68(10)98(153-109(174)80(42-26-32-50-127)142-118(183)97(67(8)9)151-107(172)78(40-24-30-48-125)138-103(168)75(37-21-27-45-122)135-93(160)60-131-102(167)89(61-155)149-101(166)70(12)134-120(185)99(71(13)157)154-115(180)85(55-74-59-130-63-132-74)145-112(177)84(136-92(159)58-128)53-72-33-17-15-18-34-72)119(184)133-69(11)100(165)137-76(38-22-28-46-123)104(169)140-81(43-44-94(161)162)106(171)150-90(62-156)116(181)144-82(51-64(2)3)110(175)147-87(57-95(163)164)114(179)139-79(41-25-31-49-126)108(173)152-96(66(6)7)117(182)141-77(39-23-29-47-124)105(170)146-86(56-91(129)158)113(178)143-83(52-65(4)5)111(176)148-88(121(186)187)54-73-35-19-16-20-36-73/h15-20,33-36,59,63-71,75-90,96-99,155-157H,14,21-32,37-58,60-62,122-128H2,1-13H3,(H2,129,158)(H,130,132)(H,131,167)(H,133,184)(H,134,185)(H,135,160)(H,136,159)(H,137,165)(H,138,168)(H,139,179)(H,140,169)(H,141,182)(H,142,183)(H,143,178)(H,144,181)(H,145,177)(H,146,170)(H,147,175)(H,148,176)(H,149,166)(H,150,171)(H,151,172)(H,152,173)(H,153,174)(H,154,180)(H,161,162)(H,163,164)(H,186,187)/t68-,69-,70-,71+,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,96-,97-,98-,99-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique& Universite de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p... |
J Med Chem 53: 5782-91 (2010)
Article DOI: 10.1021/jm1002974
BindingDB Entry DOI: 10.7270/Q2NG4RV5 |
More data for this
Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50416567
(CHEMBL1215816)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C121H201N33O34/c1-13-68(10)98(153-108(174)79(41-25-31-49-127)141-118(184)97(67(8)9)151-106(172)77(39-23-29-47-125)137-102(168)74(36-20-26-44-122)134-93(161)59-131-101(167)88(60-155)148-116(182)90(62-157)150-120(186)99(70(12)158)154-114(180)84(54-73-58-130-63-132-73)144-111(177)83(135-92(160)57-128)52-71-32-16-14-17-33-71)119(185)133-69(11)100(166)136-75(37-21-27-45-123)103(169)139-80(42-43-94(162)163)105(171)149-89(61-156)115(181)143-81(50-64(2)3)109(175)146-86(56-95(164)165)113(179)138-78(40-24-30-48-126)107(173)152-96(66(6)7)117(183)140-76(38-22-28-46-124)104(170)145-85(55-91(129)159)112(178)142-82(51-65(4)5)110(176)147-87(121(187)188)53-72-34-18-15-19-35-72/h14-19,32-35,58,63-70,74-90,96-99,155-158H,13,20-31,36-57,59-62,122-128H2,1-12H3,(H2,129,159)(H,130,132)(H,131,167)(H,133,185)(H,134,161)(H,135,160)(H,136,166)(H,137,168)(H,138,179)(H,139,169)(H,140,183)(H,141,184)(H,142,178)(H,143,181)(H,144,177)(H,145,170)(H,146,175)(H,147,176)(H,148,182)(H,149,171)(H,150,186)(H,151,172)(H,152,173)(H,153,174)(H,154,180)(H,162,163)(H,164,165)(H,187,188)/t68-,69-,70+,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,96-,97-,98-,99-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre National de la Recherche Scientifique& Universite de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of human RAD51 assessed as concentration required for half dissociation of protein/single-stranded DNA complex formation by fluorescence p... |
J Med Chem 53: 5782-91 (2010)
Article DOI: 10.1021/jm1002974
BindingDB Entry DOI: 10.7270/Q2NG4RV5 |
More data for this
Ligand-Target Pair | |
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