Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573968 (CHEMBL4851044) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human 5HT1F receptor | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573966 (CHEMBL4847626) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573964 (CHEMBL4846825) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573968 (CHEMBL4851044) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573967 (CHEMBL4865700) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573969 (CHEMBL4860576) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573965 (CHEMBL4862526) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573975 (COL-144 | LY573144 | Lasmiditan) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573970 (CHEMBL4852743) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573971 (CHEMBL4874958) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50473503 (CHEMBL2110300) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 363 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoWellcome Curated by ChEMBL | Assay Description Binding affinity towards human recombinant 5-hydroxytryptamine 1F receptor | J Med Chem 44: 681-93 (2001) Article DOI: 10.1021/jm000956k BindingDB Entry DOI: 10.7270/Q2PC354M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573972 (CHEMBL4872571) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 571 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573973 (CHEMBL4871295) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 813 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50005835 ((3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents | DrugBank Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for the affinity at 5-hydroxytryptamine 1F receptor | J Med Chem 40: 3501-3 (1997) Article DOI: 10.1021/jm9704560 BindingDB Entry DOI: 10.7270/Q2DZ07D8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50060437 (3-(3-{4-[2-(3-Fluoro-phenyl)-ethyl]-piperazin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was evaluated for the affinity at 5-hydroxytryptamine 1F receptor | J Med Chem 40: 3501-3 (1997) Article DOI: 10.1021/jm9704560 BindingDB Entry DOI: 10.7270/Q2DZ07D8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50060429 ((R)-2-(4-Fluoro-phenyl)-2-{1-[3-(5-[1,2,4]triazol-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Compound was tested for the displacement of [3H]-5-HT binding to cloned human 5-hydroxytryptamine 1F receptor stably expressed in CHO cells | J Med Chem 42: 4981-5001 (2000) BindingDB Entry DOI: 10.7270/Q20P0Z77 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1F (Homo sapiens (Human)) | BDBM50573974 (CHEMBL4861949) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at 5HT1F receptor (unknown origin) expressed in HEK293 cells measured after 60 mins by Fluo-4AM dye based FLIPR assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113782 BindingDB Entry DOI: 10.7270/Q2TQ65CK | |||||||||||
More data for this Ligand-Target Pair |