Compile Data Set for Download or QSAR

Found 5 hits of ec50 for UniProtKB: P50407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (GUINEA PIG)	BDBM50253244 (4-(2-Diphenyl)-N-(4-pyridinylmethyl)-1-piperazineh...) Show SMILES O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NCc1ccncc1 Show InChI InChI=1S/C28H34N4O/c33-28(30-23-24-14-16-29-17-15-24)13-5-2-8-18-31-19-21-32(22-20-31)27-12-7-6-11-26(27)25-9-3-1-4-10-25/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-23H2,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contraction				J Med Chem 51: 5813-22 (2008) Article DOI: 10.1021/jm800615e BindingDB Entry DOI: 10.7270/Q24749QX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (GUINEA PIG)	BDBM50253130 (2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]-1,...) Show SMILES O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1CCc2ccccc2C1 Show InChI InChI=1S/C31H37N3O/c35-31(34-20-18-26-11-6-7-14-28(26)25-34)17-5-2-10-19-32-21-23-33(24-22-32)30-16-9-8-15-29(30)27-12-3-1-4-13-27/h1,3-4,6-9,11-16H,2,5,10,17-25H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	490	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contraction				J Med Chem 51: 5813-22 (2008) Article DOI: 10.1021/jm800615e BindingDB Entry DOI: 10.7270/Q24749QX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (GUINEA PIG)	BDBM50253281 (CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...) Show SMILES O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NCc1ccc(cc1)C#N Show InChI InChI=1S/C30H34N4O/c31-23-25-14-16-26(17-15-25)24-32-30(35)13-5-2-8-18-33-19-21-34(22-20-33)29-12-7-6-11-28(29)27-9-3-1-4-10-27/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-22,24H2,(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contraction				J Med Chem 51: 5813-22 (2008) Article DOI: 10.1021/jm800615e BindingDB Entry DOI: 10.7270/Q24749QX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (GUINEA PIG)	BDBM21392 (3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...) Show SMILES NCCc1c[nH]c2ccc(cc12)C(N)=O Show InChI InChI=1S/C11H13N3O/c12-4-3-8-6-14-10-2-1-7(11(13)15)5-9(8)10/h1-2,5-6,14H,3-4,12H2,(H2,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contraction				J Med Chem 51: 5813-22 (2008) Article DOI: 10.1021/jm800615e BindingDB Entry DOI: 10.7270/Q24749QX
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 7 (GUINEA PIG)	BDBM50253208 (CHEMBL492871 | N-Benzyl-4-(2-diphenyl)-1-piperazin...) Show SMILES O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)NCc1ccccc1 Show InChI InChI=1S/C29H35N3O/c33-29(30-24-25-12-4-1-5-13-25)18-8-3-11-19-31-20-22-32(23-21-31)28-17-10-9-16-27(28)26-14-6-2-7-15-26/h1-2,4-7,9-10,12-17H,3,8,11,18-24H2,(H,30,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.50E+6	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contraction				J Med Chem 51: 5813-22 (2008) Article DOI: 10.1021/jm800615e BindingDB Entry DOI: 10.7270/Q24749QX
					More data for this Ligand-Target Pair