Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50275902 (CHEMBL525577 | D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Agonist activity at recombinant neuromedin B receptor (unknown origin) expressed in baculovirus-transduced HEK293 cells assessed as intracellular cal... | Bioorg Med Chem Lett 18: 5451-5 (2008) Article DOI: 10.1016/j.bmcl.2008.09.033 BindingDB Entry DOI: 10.7270/Q2H9952R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50147019 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-methoxy-2,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 17.7 | n/a | n/a | n/a | n/a |
Tularik Inc. Curated by ChEMBL | Assay Description Affinity of [125I]-[D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells | Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50147019 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-methoxy-2,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Tularik Inc. Curated by ChEMBL | Assay Description Affinity of [125I]-[D-Tyr0]-NMB to human Neuromedin B receptor expressed in HEK293 cells | Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50071745 (CHEMBL403317 | Compound NMB | Gly-Asn-Leu-Trp-Ala-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50147019 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-5-methoxy-2,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 132 | n/a | n/a | n/a | n/a |
Tularik Inc. Curated by ChEMBL | Assay Description Agonistic activity was determined against human Neuromedin B receptor transfected in HEK293 cells as accumulation levels of inositol phosphate | Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50127519 (CHEMBL262992 | [D-Tyr6-, Beta-Ala11, Phe13, Nle14]...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50147021 (3-[3-(2,6-Diisopropyl-phenyl)-ureido]-2,3,4,9-tetr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 603 | n/a | n/a | n/a | n/a |
Tularik Inc. Curated by ChEMBL | Assay Description Agonistic activity was determined against human Neuromedin B receptor transfected in HEK293 cells as accumulation levels of inositol phosphate | Bioorg Med Chem Lett 14: 3037-42 (2004) Article DOI: 10.1016/j.bmcl.2004.04.045 BindingDB Entry DOI: 10.7270/Q2PR7VF7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50127532 (CHEMBL438926 | Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50127522 (2-Phenylacetylamino-pentanedioic acid 5-amide 1-{[...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuromedin-B receptor (Homo sapiens (Human)) | BDBM50127535 (2-[2-(4-Chloro-phenyl)-acetylamino]-pentanedioic a...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a |
Technische Universität München Curated by ChEMBL | Assay Description Effective concentration required against nueromedin B receptor (NMB-R) in CHO cells by using FLIPR assay | J Med Chem 46: 1918-30 (2003) Article DOI: 10.1021/jm0210921 BindingDB Entry DOI: 10.7270/Q29S1QDS | |||||||||||
More data for this Ligand-Target Pair |