Found 7 hits of kd data for polymerid = 49000305 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50022815
((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)Show SMILES CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C |r| Show InChI InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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MCE
KEGG
MMDB
PC cid
PC sid
UniChem
Patents
Similars
| Article
| n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | |
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50030448
(8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | CHEMBL269732 ...)Show SMILES CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC |r,t:45| Show InChI InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19+,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
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CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
Article
| n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50285474
((E)-18-Allyl-11,21-dihydroxy-23-[(E)-2-((R)-4-hydr...)Show SMILES CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)c2ocnc2[C@H](C)C[C@H](OC)[C@H](O)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)CC(O)[C@H]1C)OC |t:46| Show InChI InChI=1S/C45H70N2O11/c1-10-13-32-19-26(2)18-27(3)20-38(55-8)41(51)39(56-9)22-28(4)40-43(57-25-46-40)44(52)47-17-12-11-14-33(47)45(53)58-42(30(6)35(49)24-36(32)50)29(5)21-31-15-16-34(48)37(23-31)54-7/h10,19,21,25,27-28,30-35,37-39,41-42,48-49,51H,1,11-18,20,22-24H2,2-9H3/b26-19+,29-21+/t27-,28+,30+,31-,32+,33-,34+,35?,37+,38-,39-,41+,42+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
| n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | |
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50285472
(18-(E)-allyl-11,21-Dihydroxy-23-[2-((R)-4-hydroxy-...)Show SMILES CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)C[C@H](C)C[C@H](OC)[C@H](O)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC |t:43| Show InChI InChI=1S/C44H71NO11/c1-10-13-32-19-26(2)18-27(3)21-39(54-8)41(50)40(55-9)22-28(4)20-37(49)43(51)45-17-12-11-14-33(45)44(52)56-42(30(6)35(47)25-36(32)48)29(5)23-31-15-16-34(46)38(24-31)53-7/h10,19,23,27-28,30-35,38-42,46-47,50H,1,11-18,20-22,24-25H2,2-9H3/b26-19+,29-23+/t27-,28-,30+,31-,32+,33-,34+,35-,38+,39-,40-,41+,42+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | |
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50285473
((8S,10R,18R,19R,22R)-8-Methoxy-10,13,18-trimethyl-...)Show SMILES CCCC1N(C)C(=O)C[C@H](C)C[C@@H](CCSCC(=O)C(=O)N2CCC[C@H](C2)C(=O)O[C@H](CCc2cccnc2)[C@H](C)CCC1=O)OC Show InChI InChI=1S/C36H55N3O7S/c1-6-9-30-31(40)14-12-26(3)33(15-13-27-10-7-17-37-22-27)46-36(44)28-11-8-18-39(23-28)35(43)32(41)24-47-19-16-29(45-5)20-25(2)21-34(42)38(30)4/h7,10,17,22,25-26,28-30,33H,6,8-9,11-16,18-21,23-24H2,1-5H3/t25-,26-,28-,29-,30?,33-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | |
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50285471
((9S,11R,19R,20R,23R)-15-sec-Butyl-9-methoxy-11,14,...)Show SMILES CCC(C)C1N(C)C(=O)C[C@H](C)C[C@@H](CCSCCC(=O)C(=O)N2CCC[C@H](C2)C(=O)O[C@H](CCc2cccnc2)[C@H](C)CCC1=O)OC Show InChI InChI=1S/C38H59N3O7S/c1-7-27(3)36-32(42)14-12-28(4)34(15-13-29-10-8-18-39-24-29)48-38(46)30-11-9-19-41(25-30)37(45)33(43)17-21-49-20-16-31(47-6)22-26(2)23-35(44)40(36)5/h8,10,18,24,26-28,30-31,34,36H,7,9,11-17,19-23,25H2,1-6H3/t26-,27?,28-,30-,31-,34-,36?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | |
Protein phosphatase 3 catalytic subunit alpha
(Homo sapiens (Human)) | BDBM50285470
((9S,11R,19R,20R,23R)-3-Hydroxy-9-methoxy-11,14,19-...)Show SMILES CCCC1N(C)C(=O)C[C@H](C)C[C@@H](CCS(=O)CCC(O)C(=O)N2CCC[C@H](C2)C(=O)O[C@H](CCc2cccnc2)[C@H](C)CCC1=O)OC Show InChI InChI=1S/C37H59N3O8S/c1-6-9-31-32(41)14-12-27(3)34(15-13-28-10-7-18-38-24-28)48-37(45)29-11-8-19-40(25-29)36(44)33(42)17-21-49(46)20-16-30(47-5)22-26(2)23-35(43)39(31)4/h7,10,18,24,26-27,29-31,33-34,42H,6,8-9,11-17,19-23,25H2,1-5H3/t26-,27-,29-,30-,31?,33?,34-,49?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Binding affinity to protein phosphatase, calcineurin (CN) was determined |
Bioorg Med Chem Lett 5: 2341-2346 (1995)
Article DOI: 10.1016/0960-894X(95)00404-H
BindingDB Entry DOI: 10.7270/Q2JQ11HB |
More data for this
Ligand-Target Pair | |
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