Compile Data Set for Download or QSAR

Found 925 hits of ic50 for UniProtKB: P18901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenate				J Med Chem 28: 1811-7 (1985) BindingDB Entry DOI: 10.7270/Q2KW5J7H
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM79172 (2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenyli...) Show SMILES OCCN1CCN(CC\C=C2\c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 Show InChI InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vivo binding affinity of the compound against dopamine (D1) receptor in rat caudate-putamen tissue using [3H]-SCH-23,390 as radioligand				Bioorg Med Chem Lett 13: 4015-7 (2003) BindingDB Entry DOI: 10.7270/Q27M07BC
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50020220 (3-Dipropylamino-chroman-8-ol | CHEMBL38428) Show SMILES CCCN(CCC)C1COc2c(O)cccc2C1 Show InChI InChI=1S/C15H23NO2/c1-3-8-16(9-4-2)13-10-12-6-5-7-14(17)15(12)18-11-13/h5-7,13,17H,3-4,8-11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranes				J Med Chem 31: 688-91 (1988) BindingDB Entry DOI: 10.7270/Q2KD2140
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029385 ((4R,5R)-8-Chloro-3,4,5-trimethyl-5-phenyl-2,3,4,5-...) Show SMILES C[C@H]1N(C)CCc2cc(Cl)c(O)cc2[C@@]1(C)c1ccccc1 Show InChI InChI=1S/C19H22ClNO/c1-13-19(2,15-7-5-4-6-8-15)16-12-18(22)17(20)11-14(16)9-10-21(13)3/h4-8,11-13,22H,9-10H2,1-3H3/t13-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.370	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50334150 (1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...) Show SMILES Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.				J Med Chem 28: 606-12 (1985) BindingDB Entry DOI: 10.7270/Q2TB193Z
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity against dopamine receptor in rat striatal membrane using [3H]haloperidol				J Med Chem 29: 1628-37 (1986) BindingDB Entry DOI: 10.7270/Q2319TVF
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50334150 (1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...) Show SMILES Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.				J Med Chem 28: 606-12 (1985) BindingDB Entry DOI: 10.7270/Q2TB193Z
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.570	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D1 by using [3H]-SCH-23,390 as radioligand				J Med Chem 38: 318-27 (1995) BindingDB Entry DOI: 10.7270/Q2057DZH
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225369 (CHEMBL295712) Show SMILES Fc1ccc(cc1)N(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C28H30F2N4O/c29-22-7-11-24(12-8-22)33(25-13-9-23(30)10-14-25)18-4-17-32-19-15-28(16-20-32)27(35)31-21-34(28)26-5-2-1-3-6-26/h1-3,5-14H,4,15-21H2,(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.				J Med Chem 28: 606-12 (1985) BindingDB Entry DOI: 10.7270/Q2TB193Z
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Carlo Bo Curated by ChEMBL					Assay Description Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECA				J Med Chem 48: 6887-96 (2005) Article DOI: 10.1021/jm058018d BindingDB Entry DOI: 10.7270/Q28C9X1X
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029378 (4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(23)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.680	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029370 (4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C22H26F2N2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-6-16(23)7-5-15)18-9-8-17(24)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029370 (4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C22H26F2N2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-6-16(23)7-5-15)18-9-8-17(24)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029387 (4-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-1,2,2-trim...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccsc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C20H25ClN2S/c1-20(2)13-23(8-7-22(20)3)19-11-17(14-6-9-24-12-14)16-5-4-15(21)10-18(16)19/h4-6,9-10,12,17,19H,7-8,11,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029375 (4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-isop...) Show SMILES CC(C)N1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C24H30ClFN2/c1-16(2)28-12-11-27(15-24(28,3)4)23-14-21(17-5-8-19(26)9-6-17)20-10-7-18(25)13-22(20)23/h5-10,13,16,21,23H,11-12,14-15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029375 (4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-isop...) Show SMILES CC(C)N1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C24H30ClFN2/c1-16(2)28-12-11-27(15-24(28,3)4)23-14-21(17-5-8-19(26)9-6-17)20-10-7-18(25)13-22(20)23/h5-10,13,16,21,23H,11-12,14-15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029377 (1-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-3,3-dimeth...) Show SMILES CC1(C)CN(CCN1)C1CC(c2ccsc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C19H23ClN2S/c1-19(2)12-22(7-6-21-19)18-10-16(13-5-8-23-11-13)15-4-3-14(20)9-17(15)18/h3-5,8-9,11,16,18,21H,6-7,10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029382 (9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6-meth...) Show SMILES CN1CCN(CC11CCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C24H28ClFN2/c1-27-12-13-28(16-24(27)10-2-3-11-24)23-15-21(17-4-7-19(26)8-5-17)20-9-6-18(25)14-22(20)23/h4-9,14,21,23H,2-3,10-13,15-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029395 (8-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-5-meth...) Show SMILES CN1CCN(CC11CCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C23H26ClFN2/c1-26-11-12-27(15-23(26)9-2-10-23)22-14-20(16-3-6-18(25)7-4-16)19-8-5-17(24)13-21(19)22/h3-8,13,20,22H,2,9-12,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.890	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50007518 ((S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)me...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC Show InChI InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.920	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.				J Med Chem 29: 61-9 (1986) BindingDB Entry DOI: 10.7270/Q2SF2ZCH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029383 (2-{9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6,9...) Show SMILES OCCN1CCN(CC11CCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C25H30ClFN2O/c26-19-5-8-21-22(18-3-6-20(27)7-4-18)16-24(23(21)15-19)28-11-12-29(13-14-30)25(17-28)9-1-2-10-25/h3-8,15,22,24,30H,1-2,9-14,16-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029384 (2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2...) Show SMILES CC1(C)CN(CCN1CCO)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C23H28ClFN2O/c1-23(2)15-26(9-10-27(23)11-12-28)22-14-20(16-3-6-18(25)7-4-16)19-8-5-17(24)13-21(19)22/h3-8,13,20,22,28H,9-12,14-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]- #NAME? from binding Dopamine receptor D1 in rat striatum				J Med Chem 33: 1756-64 (1990) BindingDB Entry DOI: 10.7270/Q23X877X
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4)				J Med Chem 24: 1440-5 (1981) BindingDB Entry DOI: 10.7270/Q2QV3PQK
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.01	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested for its affinity towards Dopamine receptor D1 in rat striatal membrane				J Med Chem 37: 2453-60 (1994) BindingDB Entry DOI: 10.7270/Q2KS6QKD
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranes				J Med Chem 27: 1607-13 (1984) BindingDB Entry DOI: 10.7270/Q2SJ1NT8
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50029400 (3-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2...) Show SMILES CC1(C)CN(CCN1CCCO)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C24H30ClFN2O/c1-24(2)16-27(11-12-28(24)10-3-13-29)23-15-21(17-4-7-19(26)8-5-17)20-9-6-18(25)14-22(20)23/h4-9,14,21,23,29H,3,10-13,15-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50012961 ((-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydro...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC Show InChI InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description In vivo binding affinity of the compound against dopamine (D1) receptor in rat caudate-putamen tissue using [3H]-SCH-23,390 as radioligand				Bioorg Med Chem Lett 13: 4015-7 (2003) BindingDB Entry DOI: 10.7270/Q27M07BC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007567 (1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...) Show SMILES CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Ability to displace [3H]-SCH- 23390 (0.2 nM) from corpus striatum of rat Dopamine receptor D1				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007567 (1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-y...) Show SMILES CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 Show InChI InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Ability to inhibit binding of [3H]-SCH- 23390 to Dopamine receptor D1 in rat striatal membranes				J Med Chem 34: 2023-30 (1991) BindingDB Entry DOI: 10.7270/Q2KD1WVC
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029378 (4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(23)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r| Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity towards rat Dopamine receptor D1 by [3H]-SCH-23,390 displacement.				J Med Chem 33: 600-7 (1990) BindingDB Entry DOI: 10.7270/Q2XS5TCP
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029377 (1-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-3,3-dimeth...) Show SMILES CC1(C)CN(CCN1)C1CC(c2ccsc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C19H23ClN2S/c1-19(2)12-22(7-6-21-19)18-10-16(13-5-8-23-11-13)15-4-3-14(20)9-17(15)18/h3-5,8-9,11,16,18,21H,6-7,10,12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride				J Med Chem 25: 363-8 (1982) BindingDB Entry DOI: 10.7270/Q2J67K44
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50029408 (4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-y...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 Show InChI InChI=1S/C23H26F4N2/c1-22(2)14-29(11-10-28(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(12-20(18)21)23(25,26)27/h4-9,12,19,21H,10-11,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225774 (CHEMBL161122) Show SMILES [H][C@@]1(CNC(=O)c2c(O)c(CC)cc(F)c2OC)CCCN1CC Show InChI InChI=1S/C17H25FN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.				J Med Chem 29: 61-9 (1986) BindingDB Entry DOI: 10.7270/Q2SF2ZCH
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029369 (4-(6-Chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-p...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccccc1 Show InChI InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50017543 ((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...) Show SMILES CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 |r| Show InChI InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatum				J Med Chem 26: 1112-6 (1983) BindingDB Entry DOI: 10.7270/Q29G5Q18
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM81195 ((+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaph...) Show SMILES NC1CCc2cc(O)c(O)cc2C1 Show InChI InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpiride				J Med Chem 25: 363-8 (1982) BindingDB Entry DOI: 10.7270/Q2J67K44
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029390 (4-[6-Bromo-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-t...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(Br)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C22H26BrFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(23)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 |r| Show InChI InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN				J Med Chem 25: 363-8 (1982) BindingDB Entry DOI: 10.7270/Q2J67K44
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50026051 (3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...) Show SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(CC)c1OC Show InChI InChI=1S/C19H30N2O3/c1-5-13-11-14(6-2)18(24-4)16(17(13)22)19(23)20-12-15-9-8-10-21(15)7-3/h11,15,22H,5-10,12H2,1-4H3,(H,20,23)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.				J Med Chem 29: 61-9 (1986) BindingDB Entry DOI: 10.7270/Q2SF2ZCH
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50225247 (CHEMBL44558) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1OCCN2c1ccccc1)c34 Show InChI InChI=1S/C19H18N2O/c1-2-5-14(6-3-1)21-9-10-22-19-15-7-4-8-16-18(15)13(12-20-16)11-17(19)21/h1-8,12,17,19-20H,9-11H2/t17-,19?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranes				J Med Chem 27: 1607-13 (1984) BindingDB Entry DOI: 10.7270/Q2SJ1NT8
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50224790 (CHEMBL333794) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])OCCN2CC Show InChI InChI=1S/C15H18N2O/c1-2-17-6-7-18-15-11-4-3-5-12-14(11)10(9-16-12)8-13(15)17/h3-5,9,13,15-16H,2,6-8H2,1H3/t13-,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranes				J Med Chem 26: 363-7 (1983) BindingDB Entry DOI: 10.7270/Q2BG2R63
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50366495 ((+)butaclamol | CHEMBL1255588) Show SMILES CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 |r| Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration inhibiting the specific binding of [3H]spiroperidol by 50%				J Med Chem 27: 165-75 (1984) BindingDB Entry DOI: 10.7270/Q24T6MMX
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranes				J Med Chem 26: 194-203 (1983) BindingDB Entry DOI: 10.7270/Q2G73GXD
					More data for this Ligand-Target Pair
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTN				J Med Chem 25: 363-8 (1982) BindingDB Entry DOI: 10.7270/Q2J67K44
					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (RAT)	BDBM50029393 (4-[3-(4-Fluoro-phenyl)-6-methyl-indan-1-yl]-1,2,2-...) Show SMILES CN1CCN(CC1(C)C)C1CC(c2ccc(C)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C23H29FN2/c1-16-5-10-19-20(17-6-8-18(24)9-7-17)14-22(21(19)13-16)26-12-11-25(4)23(2,3)15-26/h5-10,13,20,22H,11-12,14-15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029371 (1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-3,3-di...) Show SMILES CC1(C)CN(CCN1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 Show InChI InChI=1S/C21H24ClFN2/c1-21(2)13-25(10-9-24-21)20-12-18(14-3-6-16(23)7-4-14)17-8-5-15(22)11-19(17)20/h3-8,11,18,20,24H,9-10,12-13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50029394 (2-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-octahy...) Show SMILES Fc1ccc(cc1)C1CC(N2CCN3CCCCC3C2)c2cc(Cl)ccc12 Show InChI InChI=1S/C23H26ClFN2/c24-17-6-9-20-21(16-4-7-18(25)8-5-16)14-23(22(20)13-17)27-12-11-26-10-2-1-3-19(26)15-27/h4-9,13,19,21,23H,1-3,10-12,14-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity for dopamine receptor D1, activity is expressed as IC50 values.				J Med Chem 38: 4380-92 (1995) BindingDB Entry DOI: 10.7270/Q28C9V87
					More data for this Ligand-Target Pair

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