Found 30 hits of ki for UniProtKB: P43005 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM17657
((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252046
((2S,4S)-2-amino-4-(benzyloxymethyl)pentanedioic ac...)Show SMILES N[C@@H](C[C@@H](COCc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C13H17NO5/c14-11(13(17)18)6-10(12(15)16)8-19-7-9-4-2-1-3-5-9/h1-5,10-11H,6-8,14H2,(H,15,16)(H,17,18)/t10-,11-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM86711
(3-[3-Methyl-4-(4-chlorophenyl)benzoylamino]alanine...)Show SMILES Cc1cc(ccc1-c1ccc(Cl)cc1)C(=O)NC[C@H](N)C(O)=O Show InChI InChI=1S/C17H17ClN2O3/c1-10-8-12(16(21)20-9-15(19)17(22)23)4-7-14(10)11-2-5-13(18)6-3-11/h2-8,15H,9,19H2,1H3,(H,20,21)(H,22,23)/t15-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 1.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by PDSP Ki Database
| |
Mol Pharmacol 68: 974-82 (2005)
Article DOI: 10.1124/mol.105.012005 BindingDB Entry DOI: 10.7270/Q2G44NVX |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM86714
(WAY 212922 | WAY-212922)Show SMILES N[C@@H](CC(=O)Nc1ccc-2c(Cc3cc(ccc-23)C(F)(F)F)c1)C(O)=O Show InChI InChI=1S/C18H15F3N2O3/c19-18(20,21)11-1-3-13-9(6-11)5-10-7-12(2-4-14(10)13)23-16(24)8-15(22)17(25)26/h1-4,6-7,15H,5,8,22H2,(H,23,24)(H,25,26)/t15-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 1.84E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by PDSP Ki Database
| |
Mol Pharmacol 68: 974-82 (2005)
Article DOI: 10.1124/mol.105.012005 BindingDB Entry DOI: 10.7270/Q2G44NVX |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252050
((2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioi...)Show InChI InChI=1S/C8H14N2O5/c9-5(8(14)15)3-4(7(12)13)1-2-6(10)11/h4-5H,1-3,9H2,(H2,10,11)(H,12,13)(H,14,15)/t4-,5+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50251894
((2S,4R)-4-(2,2-Diphenylethylamino-3-oxopropyl)glut...)Show SMILES N[C@@H](C[C@@H](CCC(=O)NCC(c1ccccc1)c1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C22H26N2O5/c23-19(22(28)29)13-17(21(26)27)11-12-20(25)24-14-18(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-10,17-19H,11-14,23H2,(H,24,25)(H,26,27)(H,28,29)/t17-,19+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50251893
((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...)Show SMILES N[C@@H](C[C@@H](CCC(=O)NCc1ccccc1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C15H20N2O5/c16-12(15(21)22)8-11(14(19)20)6-7-13(18)17-9-10-4-2-1-3-5-10/h1-5,11-12H,6-9,16H2,(H,17,18)(H,19,20)(H,21,22)/t11-,12+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252047
((2S,4S)-4-(2-Hydroxy-2-oxoethyl)glutamic Acid | (2...)Show InChI InChI=1S/C7H11NO6/c8-4(7(13)14)1-3(6(11)12)2-5(9)10/h3-4H,1-2,8H2,(H,9,10)(H,11,12)(H,13,14)/t3-,4-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252049
((1S,3R)-1-aminopentane-1,3,5-tricarboxylic acid | ...)Show InChI InChI=1S/C8H13NO6/c9-5(8(14)15)3-4(7(12)13)1-2-6(10)11/h4-5H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252048
((2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedi...)Show InChI InChI=1S/C9H15NO6/c1-16-7(11)3-2-5(8(12)13)4-6(10)9(14)15/h5-6H,2-4,10H2,1H3,(H,12,13)(H,14,15)/t5-,6+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50251951
((2S,4S)-2-amino-4-(hydroxymethyl)pentanedioic acid...)Show InChI InChI=1S/C6H11NO5/c7-4(6(11)12)1-3(2-8)5(9)10/h3-4,8H,1-2,7H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252051
((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...)Show InChI InChI=1S/C9H16N2O5/c1-11-7(12)3-2-5(8(13)14)4-6(10)9(15)16/h5-6H,2-4,10H2,1H3,(H,11,12)(H,13,14)(H,15,16)/t5-,6+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50252662
((2S,4R)-4-(3-Propylamino-3-oxopropyl)glutamic acid...)Show SMILES CCCNC(=O)CC[C@H](C[C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H20N2O5/c1-2-5-13-9(14)4-3-7(10(15)16)6-8(12)11(17)18/h7-8H,2-6,12H2,1H3,(H,13,14)(H,15,16)(H,17,18)/t7-,8+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal
Curated by ChEMBL
| Assay Description Inhibition of [3H]D-Asp uptake at human EAAT3 in HEK293 cells |
J Med Chem 51: 4085-92 (2008)
Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM86712
(CAS_868359-05-1 | N-[4-(2-BROMO-4,5-DIFLUOROPHENOX...)Show SMILES N[C@@H](CC(=O)Nc1ccc(Oc2cc(F)c(F)cc2Br)cc1)C(O)=O |r| Show InChI InChI=1S/C16H13BrF2N2O4/c17-10-5-11(18)12(19)6-14(10)25-9-3-1-8(2-4-9)21-15(22)7-13(20)16(23)24/h1-6,13H,7,20H2,(H,21,22)(H,23,24)/t13-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 3.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by PDSP Ki Database
| |
Mol Pharmacol 68: 974-82 (2005)
Article DOI: 10.1124/mol.105.012005 BindingDB Entry DOI: 10.7270/Q2G44NVX |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM86713
(WAY 213394 | WAY-213394)Show InChI InChI=1S/C17H18N2O3/c1-11-4-2-3-5-14(11)12-6-8-13(9-7-12)19-16(20)10-15(18)17(21)22/h2-9,15H,10,18H2,1H3,(H,19,20)(H,21,22)/t15-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 6.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by PDSP Ki Database
| |
Mol Pharmacol 68: 974-82 (2005)
Article DOI: 10.1124/mol.105.012005 BindingDB Entry DOI: 10.7270/Q2G44NVX |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50031704
((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)Show InChI InChI=1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,4+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM86316
(WAY-855)Show SMILES [H][C@@]12C[C@@]3([H])CC1[C@]2([H])[C@@]3(N)C(O)=O |r,wU:9.12,3.3,wD:1.0,7.9,TLB:10:9:2:6.5,11:9:2:6.5,(4,2.31,;2.67,1.54,;2.67,,;1.33,-.77,;2.1,-2.1,;1.73,.82,;1.33,2.31,;,1.54,;-1.09,2.63,;;-.4,-1.49,;-1.54,,;-2.31,1.33,;-2.63,-1.09,)| Show InChI InChI=1S/C8H11NO2/c9-8(7(10)11)3-1-4-5(2-3)6(4)8/h3-6H,1-2,9H2,(H,10,11)/t3-,4+,5?,6+,8+/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by PDSP Ki Database
| |
Br J Pharmacol 140: 839-46 (2003)
Article DOI: 10.1038/sj.bjp.0705509 BindingDB Entry DOI: 10.7270/Q2HD7T74 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197103
((2S,1'R,2'S)-2-(2'-Carboxycyclobutyl)glycine | CHE...)Show InChI InChI=1S/C7H11NO4/c8-5(7(11)12)3-1-2-4(3)6(9)10/h3-5H,1-2,8H2,(H,9,10)(H,11,12)/t3-,4+,5+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assay |
J Med Chem 49: 6532-8 (2006)
Article DOI: 10.1021/jm060822s BindingDB Entry DOI: 10.7270/Q2S46RMK |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50088230
((2S,4R)-4-propylglutamic acid | 2-Amino-4-propyl-p...)Show InChI InChI=1S/C8H15NO4/c1-2-3-5(7(10)11)4-6(9)8(12)13/h5-6H,2-4,9H2,1H3,(H,10,11)(H,12,13)/t5-,6+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50178684
((2S,4R)-4-ethylglutamic acid | CHEMBL372124)Show InChI InChI=1S/C7H13NO4/c1-2-4(6(9)10)3-5(8)7(11)12/h4-5H,2-3,8H2,1H3,(H,9,10)(H,11,12)/t4-,5+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50180145
((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)Show SMILES OC(=O)[C@H]1CC[C@H]2CN[C@@H]([C@@H]12)C(O)=O Show InChI InChI=1S/C9H13NO4/c11-8(12)5-2-1-4-3-10-7(6(4)5)9(13)14/h4-7,10H,1-3H2,(H,11,12)(H,13,14)/t4-,5-,6+,7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Activity against human EAAT3 transfected in HEK293 cells |
J Med Chem 49: 172-8 (2006)
Article DOI: 10.1021/jm0508336 BindingDB Entry DOI: 10.7270/Q2GM86WB |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197104
((2S,1'R,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)Show InChI InChI=1S/C7H11NO4/c8-5(7(11)12)3-1-2-4(3)6(9)10/h3-5H,1-2,8H2,(H,9,10)(H,11,12)/t3-,4-,5+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assay |
J Med Chem 49: 6532-8 (2006)
Article DOI: 10.1021/jm060822s BindingDB Entry DOI: 10.7270/Q2S46RMK |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50178683
((2S,4S)-4-isopropylglutamic acid | CHEMBL199564)Show InChI InChI=1S/C8H15NO4/c1-4(2)5(7(10)11)3-6(9)8(12)13/h4-6H,3,9H2,1-2H3,(H,10,11)(H,12,13)/t5-,6-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50197105
((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)Show InChI InChI=1S/C7H11NO4/c8-5(7(11)12)3-1-2-4(3)6(9)10/h3-5H,1-2,8H2,(H,9,10)(H,11,12)/t3-,4+,5-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Inhibition of human EAAT3 expressed in HEK293 cells by FLIPR membrane potential assay |
J Med Chem 49: 6532-8 (2006)
Article DOI: 10.1021/jm060822s BindingDB Entry DOI: 10.7270/Q2S46RMK |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50178688
((2S,4R)-4-benzylglutamic acid | CHEMBL198618)Show InChI InChI=1S/C12H15NO4/c13-10(12(16)17)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9-10H,6-7,13H2,(H,14,15)(H,16,17)/t9-,10+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50178685
((2S,4R)-4-butylglutamic acid | CHEMBL381004)Show InChI InChI=1S/C9H17NO4/c1-2-3-4-6(8(11)12)5-7(10)9(13)14/h6-7H,2-5,10H2,1H3,(H,11,12)(H,13,14)/t6-,7+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50178686
((2S,4R)-4-isopentylglutamic acid | CHEMBL197176)Show InChI InChI=1S/C10H19NO4/c1-6(2)3-4-7(9(12)13)5-8(11)10(14)15/h6-8H,3-5,11H2,1-2H3,(H,12,13)(H,14,15)/t7-,8+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50088220
((2S,4R)-4-pentylglutamic acid | 2-Amino-4-pentyl-p...)Show InChI InChI=1S/C10H19NO4/c1-2-3-4-5-7(9(12)13)6-8(11)10(14)15/h7-8H,2-6,11H2,1H3,(H,12,13)(H,14,15)/t7-,8+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50178687
((2S,4R)-4-isobutylglutamic acid | CHEMBL199617)Show InChI InChI=1S/C9H17NO4/c1-5(2)3-6(8(11)12)4-7(10)9(13)14/h5-7H,3-4,10H2,1-2H3,(H,11,12)(H,13,14)/t6-,7+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Blaise Pascal
Curated by ChEMBL
| Assay Description Binding affinity to human EAAT3 expressed in HEK293 cells in FMP (FLPR) assay |
J Med Chem 48: 7980-92 (2005)
Article DOI: 10.1021/jm050597z BindingDB Entry DOI: 10.7270/Q2MP52V1 |
More data for this Ligand-Target Pair | |
Excitatory amino acid transporter 3
(Homo sapiens (Human)) | BDBM50180146
((3S,5S)-2-aza-bicyclo[2.2.1]heptane-3,5-dicarboxyl...)Show SMILES OC(=O)[C@H]1CC2CC1[C@H](N2)C(O)=O |THB:10:8:6:4.3,1:3:8.9:6| Show InChI InChI=1S/C8H11NO4/c10-7(11)5-2-3-1-4(5)6(9-3)8(12)13/h3-6,9H,1-2H2,(H,10,11)(H,12,13)/t3?,4?,5-,6-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >4.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description Activity against human EAAT3 transfected in HEK293 cells |
J Med Chem 49: 172-8 (2006)
Article DOI: 10.1021/jm0508336 BindingDB Entry DOI: 10.7270/Q2GM86WB |
More data for this Ligand-Target Pair | |