Found 142 hits of ic50 data for polymerid = 49000597,49000598 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM392076
(US10301272, Example 7/9)Show SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)N[C@H]2C[C@@H](C2)C(O)=O)c2ccccc12 |r,wU:27.28,wD:29.33,(8.76,1.15,;7.67,.06,;6.19,.46,;7.28,1.55,;8.07,-1.42,;6.98,-2.51,;6.59,-4,;8.07,-3.6,;5.5,-2.11,;5.1,-.63,;3.61,-.23,;2.52,-1.32,;1.03,-.92,;.56,.55,;-.98,.55,;-1.46,-.92,;-.21,-1.82,;-.21,-3.36,;-1.55,-4.13,;-2.88,-3.36,;-4.21,-4.13,;-4.21,-5.67,;-2.88,-6.44,;-1.55,-5.67,;-2.07,1.64,;-1.67,3.12,;-3.56,1.24,;-4.65,2.33,;-6.19,2.33,;-6.19,3.87,;-4.65,3.87,;-7.28,4.96,;-6.88,6.44,;-8.76,4.56,;2.92,-2.8,;1.83,-3.89,;2.23,-5.38,;3.72,-5.78,;4.81,-4.69,;4.41,-3.2,)| Show InChI InChI=1S/C30H37N3O5S2/c1-30(2,3)33-40(37,38)25-14-13-23(21-11-7-8-12-22(21)25)26-24(15-18-9-5-4-6-10-18)32-28(39-26)27(34)31-20-16-19(17-20)29(35)36/h7-8,11-14,18-20,33H,4-6,9-10,15-17H2,1-3H3,(H,31,34)(H,35,36)/t19-,20- | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Phenex Pharmaceuticals AG
Curated by ChEMBL
| Assay Description
Displacement of [125I]-endothelin-1 from human recombinant GAL2 receptor after 120 mins by scintillation counting analysis |
Bioorg Med Chem Lett 28: 1446-1455 (2018)
Article DOI: 10.1016/j.bmcl.2018.03.093
BindingDB Entry DOI: 10.7270/Q27W6FPC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50378616
(GALANIN)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O |r,wU:119.123,135.139,162.167,173.179,200.207,224.233,13.20,42.48,50.61,113.119,93.96,wD:2.2,127.131,145.150,156.161,183.190,191.198,216.224,4.4,8.8,23.23,34.40,66.69,71.76,77.84,85.92,97.112,(19.04,-36.25,;18.27,-34.92,;16.73,-34.92,;15.96,-36.25,;15.96,-33.59,;14.42,-33.59,;13.65,-34.92,;14.42,-36.25,;12.11,-34.92,;11.34,-36.25,;11.34,-33.59,;9.8,-33.59,;9.03,-34.92,;9.03,-32.26,;9.8,-30.92,;9.03,-29.59,;9.66,-28.19,;8.52,-27.16,;7.18,-27.92,;7.5,-29.43,;7.49,-32.26,;6.72,-33.59,;7.49,-34.92,;5.19,-33.67,;4.35,-34.96,;2.86,-34.56,;2.78,-33.03,;4.21,-32.48,;4.62,-30.99,;6.1,-30.59,;3.53,-29.9,;2.04,-30.3,;.95,-29.21,;-.53,-29.61,;1.35,-27.72,;.26,-26.63,;-1.23,-27.03,;-2.31,-25.94,;-1.62,-28.52,;2.83,-27.32,;3.24,-25.83,;2.15,-24.75,;4.72,-25.44,;5.81,-26.53,;5.41,-28.01,;3.93,-28.41,;6.5,-29.11,;5.24,-23.51,;3.83,-22.09,;2.34,-22.49,;4.34,-20.16,;5.83,-19.76,;6.92,-20.85,;8.4,-20.45,;9.5,-21.54,;9.09,-23.02,;10.19,-24.11,;7.61,-23.42,;6.52,-22.33,;2.93,-18.75,;1.44,-19.14,;1.04,-20.63,;.03,-17.72,;-1.46,-18.12,;-1.86,-19.61,;-.77,-20.7,;-3.35,-20.01,;-3.75,-21.5,;-4.43,-18.92,;-5.93,-19.32,;-6.32,-20.81,;-7.01,-18.23,;-8.5,-18.63,;-8.9,-20.12,;-6.61,-16.74,;-7.7,-15.65,;-9.19,-16.05,;-7.3,-14.17,;-8.39,-13.08,;-9.88,-13.47,;-10.97,-12.39,;-10.28,-14.97,;-5.82,-13.77,;-5.42,-12.28,;-6.51,-11.19,;-3.93,-11.88,;-3.53,-10.4,;-4.62,-9.31,;-6.11,-9.71,;-4.22,-7.82,;-2.84,-12.97,;-1.35,-12.57,;-.95,-11.09,;-.27,-13.66,;1.22,-13.27,;2.31,-14.35,;1.91,-15.84,;3.79,-13.96,;4.12,-12.45,;5.58,-11.97,;6.06,-10.51,;7.59,-10.51,;8.07,-11.97,;9.48,-12.6,;9.64,-14.13,;8.39,-15.04,;6.99,-14.41,;6.82,-12.88,;4.89,-15.04,;4.49,-16.53,;3,-16.93,;5.58,-17.62,;7.06,-17.22,;-.66,-15.15,;.43,-16.24,;-2.15,-15.55,;16.73,-32.26,;18.27,-32.26,;15.96,-30.92,;16.73,-29.59,;15.96,-28.26,;14.42,-28.26,;13.65,-29.59,;13.65,-26.93,;18.27,-29.59,;19.04,-28.26,;19.04,-30.92,;20.57,-30.92,;21.35,-32.26,;22.88,-32.26,;23.66,-33.59,;23.66,-30.92,;21.35,-29.59,;22.88,-29.59,;20.57,-28.26,;21.35,-26.93,;20.57,-25.59,;21.35,-24.26,;20.72,-22.86,;21.87,-21.82,;23.2,-22.59,;22.88,-24.09,;22.88,-26.93,;23.66,-28.26,;23.66,-25.59,;25.19,-25.59,;25.97,-26.93,;27.5,-26.93,;28.27,-25.59,;29.81,-25.59,;30.58,-24.26,;32.12,-24.26,;29.81,-22.92,;25.97,-24.26,;27.5,-24.26,;25.19,-22.92,;25.97,-21.59,;27.5,-21.59,;28.27,-20.26,;25.19,-20.26,;25.97,-18.92,;23.66,-20.26,;22.88,-18.92,;21.35,-18.92,;20.57,-17.59,;19.04,-17.59,;18.27,-16.26,;19.04,-14.93,;20.57,-14.93,;21.35,-16.26,;23.66,-17.59,;25.19,-17.59,;22.88,-16.26,;23.66,-14.93,;22.88,-13.59,;23.66,-12.26,;23.03,-10.86,;24.18,-9.82,;25.51,-10.59,;25.19,-12.1,;25.19,-14.93,;25.97,-16.26,;25.97,-13.59,;27.5,-13.59,;28.27,-14.93,;29.81,-14.93,;30.58,-16.26,;30.58,-13.59,;28.27,-12.26,;29.81,-12.26,;27.5,-10.93,;28.27,-9.6,;29.81,-9.6,;30.58,-10.93,;32.12,-10.93,;32.89,-12.26,;34.43,-12.26,;27.5,-8.26,;28.27,-6.92,;25.97,-8.26,;25.19,-6.92,;23.66,-6.92,;22.88,-5.59,;21.35,-5.59,;20.57,-4.26,;21.35,-2.93,;20.57,-1.59,;22.88,-2.93,;23.66,-4.26,;25.97,-5.59,;27.5,-5.59,;25.19,-4.26,;25.97,-2.93,;27.5,-2.93,;28.27,-4.26,;28.27,-1.59,;29.81,-1.59,;30.58,-2.93,;32.12,-2.93,;32.89,-4.26,;32.89,-1.59,;30.58,-.26,;32.12,-.26,;29.81,1.07,;30.58,2.4,;29.81,3.74,;32.12,2.4,;32.89,3.74,;32.89,1.07,)| Show InChI InChI=1S/C146H213N43O40/c1-15-75(10)119(187-123(207)78(13)167-129(213)101(51-84-60-154-68-162-84)182-143(227)110-31-24-42-189(110)116(200)65-161-124(208)93(43-71(2)3)173-130(214)95(45-73(6)7)174-132(216)98(49-82-34-38-88(194)39-35-82)170-114(198)63-159-122(206)77(12)166-141(225)108(66-190)186-137(221)105(55-112(150)196)179-131(215)96(46-74(8)9)183-145(229)120(79(14)192)188-140(224)100(168-113(197)58-148)50-83-59-158-90-28-20-19-27-89(83)90)144(228)184-107(57-118(203)204)139(223)180-104(54-111(149)195)136(220)178-102(52-85-61-155-69-163-85)134(218)172-92(30-23-41-157-146(152)153)127(211)185-109(67-191)142(226)176-99(47-80-25-17-16-18-26-80)133(217)177-103(53-86-62-156-70-164-86)135(219)181-106(56-117(201)202)138(222)171-91(29-21-22-40-147)126(210)175-97(48-81-32-36-87(193)37-33-81)125(209)160-64-115(199)169-94(44-72(4)5)128(212)165-76(11)121(151)205/h16-20,25-28,32-39,59-62,68-79,91-110,119-120,158,190-194H,15,21-24,29-31,40-58,63-67,147-148H2,1-14H3,(H2,149,195)(H2,150,196)(H2,151,205)(H,154,162)(H,155,163)(H,156,164)(H,159,206)(H,160,209)(H,161,208)(H,165,212)(H,166,225)(H,167,213)(H,168,197)(H,169,199)(H,170,198)(H,171,222)(H,172,218)(H,173,214)(H,174,216)(H,175,210)(H,176,226)(H,177,217)(H,178,220)(H,179,215)(H,180,223)(H,181,219)(H,182,227)(H,183,229)(H,184,228)(H,185,211)(H,186,221)(H,187,207)(H,188,224)(H,201,202)(H,203,204)(H4,152,153,157)/t75-,76-,77-,78-,79+,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-,120-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Organic Synthesis
Curated by ChEMBL
| Assay Description
Binding affinity to human GAL2 receptor by radioligand displacement assay |
Bioorg Med Chem 21: 2764-71 (2013)
Article DOI: 10.1016/j.bmc.2013.03.016
BindingDB Entry DOI: 10.7270/Q2N87C5Q |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50378616
(GALANIN)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O |r,wU:119.123,135.139,162.167,173.179,200.207,224.233,13.20,42.48,50.61,113.119,93.96,wD:2.2,127.131,145.150,156.161,183.190,191.198,216.224,4.4,8.8,23.23,34.40,66.69,71.76,77.84,85.92,97.112,(19.04,-36.25,;18.27,-34.92,;16.73,-34.92,;15.96,-36.25,;15.96,-33.59,;14.42,-33.59,;13.65,-34.92,;14.42,-36.25,;12.11,-34.92,;11.34,-36.25,;11.34,-33.59,;9.8,-33.59,;9.03,-34.92,;9.03,-32.26,;9.8,-30.92,;9.03,-29.59,;9.66,-28.19,;8.52,-27.16,;7.18,-27.92,;7.5,-29.43,;7.49,-32.26,;6.72,-33.59,;7.49,-34.92,;5.19,-33.67,;4.35,-34.96,;2.86,-34.56,;2.78,-33.03,;4.21,-32.48,;4.62,-30.99,;6.1,-30.59,;3.53,-29.9,;2.04,-30.3,;.95,-29.21,;-.53,-29.61,;1.35,-27.72,;.26,-26.63,;-1.23,-27.03,;-2.31,-25.94,;-1.62,-28.52,;2.83,-27.32,;3.24,-25.83,;2.15,-24.75,;4.72,-25.44,;5.81,-26.53,;5.41,-28.01,;3.93,-28.41,;6.5,-29.11,;5.24,-23.51,;3.83,-22.09,;2.34,-22.49,;4.34,-20.16,;5.83,-19.76,;6.92,-20.85,;8.4,-20.45,;9.5,-21.54,;9.09,-23.02,;10.19,-24.11,;7.61,-23.42,;6.52,-22.33,;2.93,-18.75,;1.44,-19.14,;1.04,-20.63,;.03,-17.72,;-1.46,-18.12,;-1.86,-19.61,;-.77,-20.7,;-3.35,-20.01,;-3.75,-21.5,;-4.43,-18.92,;-5.93,-19.32,;-6.32,-20.81,;-7.01,-18.23,;-8.5,-18.63,;-8.9,-20.12,;-6.61,-16.74,;-7.7,-15.65,;-9.19,-16.05,;-7.3,-14.17,;-8.39,-13.08,;-9.88,-13.47,;-10.97,-12.39,;-10.28,-14.97,;-5.82,-13.77,;-5.42,-12.28,;-6.51,-11.19,;-3.93,-11.88,;-3.53,-10.4,;-4.62,-9.31,;-6.11,-9.71,;-4.22,-7.82,;-2.84,-12.97,;-1.35,-12.57,;-.95,-11.09,;-.27,-13.66,;1.22,-13.27,;2.31,-14.35,;1.91,-15.84,;3.79,-13.96,;4.12,-12.45,;5.58,-11.97,;6.06,-10.51,;7.59,-10.51,;8.07,-11.97,;9.48,-12.6,;9.64,-14.13,;8.39,-15.04,;6.99,-14.41,;6.82,-12.88,;4.89,-15.04,;4.49,-16.53,;3,-16.93,;5.58,-17.62,;7.06,-17.22,;-.66,-15.15,;.43,-16.24,;-2.15,-15.55,;16.73,-32.26,;18.27,-32.26,;15.96,-30.92,;16.73,-29.59,;15.96,-28.26,;14.42,-28.26,;13.65,-29.59,;13.65,-26.93,;18.27,-29.59,;19.04,-28.26,;19.04,-30.92,;20.57,-30.92,;21.35,-32.26,;22.88,-32.26,;23.66,-33.59,;23.66,-30.92,;21.35,-29.59,;22.88,-29.59,;20.57,-28.26,;21.35,-26.93,;20.57,-25.59,;21.35,-24.26,;20.72,-22.86,;21.87,-21.82,;23.2,-22.59,;22.88,-24.09,;22.88,-26.93,;23.66,-28.26,;23.66,-25.59,;25.19,-25.59,;25.97,-26.93,;27.5,-26.93,;28.27,-25.59,;29.81,-25.59,;30.58,-24.26,;32.12,-24.26,;29.81,-22.92,;25.97,-24.26,;27.5,-24.26,;25.19,-22.92,;25.97,-21.59,;27.5,-21.59,;28.27,-20.26,;25.19,-20.26,;25.97,-18.92,;23.66,-20.26,;22.88,-18.92,;21.35,-18.92,;20.57,-17.59,;19.04,-17.59,;18.27,-16.26,;19.04,-14.93,;20.57,-14.93,;21.35,-16.26,;23.66,-17.59,;25.19,-17.59,;22.88,-16.26,;23.66,-14.93,;22.88,-13.59,;23.66,-12.26,;23.03,-10.86,;24.18,-9.82,;25.51,-10.59,;25.19,-12.1,;25.19,-14.93,;25.97,-16.26,;25.97,-13.59,;27.5,-13.59,;28.27,-14.93,;29.81,-14.93,;30.58,-16.26,;30.58,-13.59,;28.27,-12.26,;29.81,-12.26,;27.5,-10.93,;28.27,-9.6,;29.81,-9.6,;30.58,-10.93,;32.12,-10.93,;32.89,-12.26,;34.43,-12.26,;27.5,-8.26,;28.27,-6.92,;25.97,-8.26,;25.19,-6.92,;23.66,-6.92,;22.88,-5.59,;21.35,-5.59,;20.57,-4.26,;21.35,-2.93,;20.57,-1.59,;22.88,-2.93,;23.66,-4.26,;25.97,-5.59,;27.5,-5.59,;25.19,-4.26,;25.97,-2.93,;27.5,-2.93,;28.27,-4.26,;28.27,-1.59,;29.81,-1.59,;30.58,-2.93,;32.12,-2.93,;32.89,-4.26,;32.89,-1.59,;30.58,-.26,;32.12,-.26,;29.81,1.07,;30.58,2.4,;29.81,3.74,;32.12,2.4,;32.89,3.74,;32.89,1.07,)| Show InChI InChI=1S/C146H213N43O40/c1-15-75(10)119(187-123(207)78(13)167-129(213)101(51-84-60-154-68-162-84)182-143(227)110-31-24-42-189(110)116(200)65-161-124(208)93(43-71(2)3)173-130(214)95(45-73(6)7)174-132(216)98(49-82-34-38-88(194)39-35-82)170-114(198)63-159-122(206)77(12)166-141(225)108(66-190)186-137(221)105(55-112(150)196)179-131(215)96(46-74(8)9)183-145(229)120(79(14)192)188-140(224)100(168-113(197)58-148)50-83-59-158-90-28-20-19-27-89(83)90)144(228)184-107(57-118(203)204)139(223)180-104(54-111(149)195)136(220)178-102(52-85-61-155-69-163-85)134(218)172-92(30-23-41-157-146(152)153)127(211)185-109(67-191)142(226)176-99(47-80-25-17-16-18-26-80)133(217)177-103(53-86-62-156-70-164-86)135(219)181-106(56-117(201)202)138(222)171-91(29-21-22-40-147)126(210)175-97(48-81-32-36-87(193)37-33-81)125(209)160-64-115(199)169-94(44-72(4)5)128(212)165-76(11)121(151)205/h16-20,25-28,32-39,59-62,68-79,91-110,119-120,158,190-194H,15,21-24,29-31,40-58,63-67,147-148H2,1-14H3,(H2,149,195)(H2,150,196)(H2,151,205)(H,154,162)(H,155,163)(H,156,164)(H,159,206)(H,160,209)(H,161,208)(H,165,212)(H,166,225)(H,167,213)(H,168,197)(H,169,199)(H,170,198)(H,171,222)(H,172,218)(H,173,214)(H,174,216)(H,175,210)(H,176,226)(H,177,217)(H,178,220)(H,179,215)(H,180,223)(H,181,219)(H,182,227)(H,183,229)(H,184,228)(H,185,211)(H,186,221)(H,187,207)(H,188,224)(H,201,202)(H,203,204)(H4,152,153,157)/t75-,76-,77-,78-,79+,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,119-,120-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Siena
Curated by ChEMBL
| Assay Description
Binding affinity to human GAL2 receptor by radioligand displacement assay |
Eur J Med Chem 63: 85-94 (2013)
Article DOI: 10.1016/j.ejmech.2013.01.044
BindingDB Entry DOI: 10.7270/Q2JH3NKC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50208989
(CHEMBL506553)Show SMILES [H][C@](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@]1([H])CCCN1C(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(C)C)([C@@H](C)O)C(=O)N[C@@H](CO)C(O)=O |r| Show InChI InChI=1S/C139H210N42O43/c1-65(2)38-84(165-121(206)86(40-67(5)6)166-123(208)88(43-75-31-33-79(188)34-32-75)161-106(193)55-151-114(199)70(11)157-131(216)97(59-182)175-127(212)95(49-104(144)191)170-122(207)87(41-68(7)8)173-136(221)112(72(13)186)180-130(215)90(159-105(192)51-141)44-76-52-150-81-27-19-18-26-80(76)81)116(201)154-58-109(196)181-37-23-30-101(181)134(219)172-91(45-77-53-147-63-155-77)120(205)158-71(12)115(200)178-111(69(9)10)135(220)153-57-108(195)162-94(48-103(143)190)126(211)168-92(46-78-54-148-64-156-78)125(210)164-83(29-22-36-149-139(145)146)119(204)174-98(60-183)132(217)167-89(42-74-24-16-15-17-25-74)124(209)176-99(61-184)133(218)171-96(50-110(197)198)128(213)163-82(28-20-21-35-140)118(203)169-93(47-102(142)189)117(202)152-56-107(194)160-85(39-66(3)4)129(214)179-113(73(14)187)137(222)177-100(62-185)138(223)224/h15-19,24-27,31-34,52-54,63-73,82-101,111-113,150,182-188H,20-23,28-30,35-51,55-62,140-141H2,1-14H3,(H2,142,189)(H2,143,190)(H2,144,191)(H,147,155)(H,148,156)(H,151,199)(H,152,202)(H,153,220)(H,154,201)(H,157,216)(H,158,205)(H,159,192)(H,160,194)(H,161,193)(H,162,195)(H,163,213)(H,164,210)(H,165,206)(H,166,208)(H,167,217)(H,168,211)(H,169,203)(H,170,207)(H,171,218)(H,172,219)(H,173,221)(H,174,204)(H,175,212)(H,176,209)(H,177,222)(H,178,200)(H,179,214)(H,180,215)(H,197,198)(H,223,224)(H4,145,146,149)/t70-,71-,72+,73+,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,111-,112-,113-/m0/s1 | PDB
Reactome pathway
KEGG
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CHEMBL
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PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from human recombinant GAL2 receptor expressed in CHO cells measured after 120 mins by scintillation counting method |
Bioorg Med Chem 25: 471-482 (2017)
Article DOI: 10.1016/j.bmc.2016.11.014
BindingDB Entry DOI: 10.7270/Q2CF9S3S |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256745
((2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophen...)Show SMILES N[C@@H](COC(c1cccc(F)c1)c1ccccc1OCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C23H22FNO4/c24-18-10-6-9-17(13-18)22(29-15-20(25)23(26)27)19-11-4-5-12-21(19)28-14-16-7-2-1-3-8-16/h1-13,20,22H,14-15,25H2,(H,26,27)/t20-,22?/m0/s1 | PDB
Reactome pathway
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CHEMBL
MCE
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UniChem
| Article
PubMed
| n/a | n/a | 21.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256746
((3S,6S,9S,15aR)-9-sec-butyl-6-((1-methoxy-1H-indol...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2cn(OC)c3ccccc23)NC(=O)[C@H](CCCCC(C)=O)NC(=O)[C@H]2CCCCN2C1=O |r| Show InChI InChI=1S/C32H45N5O6/c1-5-20(2)28-32(42)36-17-11-10-16-27(36)31(41)33-24(14-8-6-12-21(3)38)29(39)34-25(30(40)35-28)18-22-19-37(43-4)26-15-9-7-13-23(22)26/h7,9,13,15,19-20,24-25,27-28H,5-6,8,10-12,14,16-18H2,1-4H3,(H,33,41)(H,34,39)(H,35,40)/t20-,24-,25-,27+,28-/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
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UniChem
Similars
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PubMed
| n/a | n/a | 87.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256706
((3S,6S,9S,12S)-3-benzyl-6,9,12-tri-sec-butyl-1,4,7...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@@H](C)CC |r| Show InChI InChI=1S/C27H42N4O4/c1-7-16(4)21-25(33)28-20(15-19-13-11-10-12-14-19)24(32)29-22(17(5)8-2)26(34)31-23(18(6)9-3)27(35)30-21/h10-14,16-18,20-23H,7-9,15H2,1-6H3,(H,28,33)(H,29,32)(H,30,35)(H,31,34)/t16-,17-,18-,20-,21-,22-,23-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
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PubMed
| n/a | n/a | 226 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256665
((3S,6S,9S,12S)-3-benzyl-9,12-di-sec-butyl-6-((2S,3...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@H](C)[C@@H](C)O |r| Show InChI InChI=1S/C27H42N4O5/c1-7-15(3)21-25(34)30-22(16(4)8-2)26(35)31-23(17(5)18(6)32)27(36)28-20(24(33)29-21)14-19-12-10-9-11-13-19/h9-13,15-18,20-23,32H,7-8,14H2,1-6H3,(H,28,36)(H,29,33)(H,30,34)(H,31,35)/t15-,16-,17+,18+,20-,21-,22-,23-/m0/s1 | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 278 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358677
(CHEMBL1922007)Show SMILES COc1ccc(Nc2nc(Nc3ccc(OC(F)(F)F)cc3)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H24F3N5O2/c1-32-18-9-5-17(6-10-18)28-22-29-20(15-21(30-22)31-13-3-2-4-14-31)27-16-7-11-19(12-8-16)33-23(24,25)26/h5-12,15H,2-4,13-14H2,1H3,(H2,27,28,29,30) | PDB
Reactome pathway
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UniChem
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PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358683
(CHEMBL1922013)Show SMILES COc1ccc(Nc2nc(Nc3cccc(F)c3C)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H26FN5O/c1-16-19(24)7-6-8-20(16)26-21-15-22(29-13-4-3-5-14-29)28-23(27-21)25-17-9-11-18(30-2)12-10-17/h6-12,15H,3-5,13-14H2,1-2H3,(H2,25,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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UniChem
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PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358676
(CHEMBL1922006)Show SMILES COc1ccc(Nc2nc(Nc3cccc(OC(F)(F)F)c3)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H24F3N5O2/c1-32-18-10-8-16(9-11-18)28-22-29-20(15-21(30-22)31-12-3-2-4-13-31)27-17-6-5-7-19(14-17)33-23(24,25)26/h5-11,14-15H,2-4,12-13H2,1H3,(H2,27,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358680
(CHEMBL1922010)Show SMILES COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H26FN5O2/c1-30-18-9-6-16(7-10-18)26-23-27-21(15-22(28-23)29-12-4-3-5-13-29)25-17-8-11-20(31-2)19(24)14-17/h6-11,14-15H,3-5,12-13H2,1-2H3,(H2,25,26,27,28) | PDB
Reactome pathway
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UniChem
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PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358675
(CHEMBL1922005)Show SMILES COc1ccc(Nc2nc(Nc3cc(C)ccc3C)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C24H29N5O/c1-17-7-8-18(2)21(15-17)26-22-16-23(29-13-5-4-6-14-29)28-24(27-22)25-19-9-11-20(30-3)12-10-19/h7-12,15-16H,4-6,13-14H2,1-3H3,(H2,25,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256704
((3S,6S,9S,12S)-3-benzyl-9-sec-butyl-6-((2S,3R)-3-h...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC1=O)[C@H](C)[C@@H](C)O)C(C)C |r| Show InChI InChI=1S/C26H40N4O5/c1-7-15(4)21-25(34)30-22(16(5)17(6)31)26(35)27-19(13-18-11-9-8-10-12-18)23(32)28-20(14(2)3)24(33)29-21/h8-12,14-17,19-22,31H,7,13H2,1-6H3,(H,27,35)(H,28,32)(H,29,33)(H,30,34)/t15-,16+,17+,19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358679
(CHEMBL1922009)Show SMILES COc1ccc(Nc2nc(Nc3cccc(OC(F)F)c3)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H25F2N5O2/c1-31-18-10-8-16(9-11-18)27-23-28-20(15-21(29-23)30-12-3-2-4-13-30)26-17-6-5-7-19(14-17)32-22(24)25/h5-11,14-15,22H,2-4,12-13H2,1H3,(H2,26,27,28,29) | PDB
Reactome pathway
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256705
((3S,6S,9S,12S)-3-benzyl-6-((2S,3R)-3-hydroxybutan-...)Show SMILES CC(C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@H](C)[C@@H](C)O |r| Show InChI InChI=1S/C25H38N4O5/c1-13(2)19-23(32)28-20(14(3)4)24(33)29-21(15(5)16(6)30)25(34)26-18(22(31)27-19)12-17-10-8-7-9-11-17/h7-11,13-16,18-21,30H,12H2,1-6H3,(H,26,34)(H,27,31)(H,28,32)(H,29,33)/t15-,16-,18+,19+,20+,21+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 542 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358658
(CHEMBL1921999)Show SMILES COc1ccc(Nc2cc(Nc3cccc(OC(F)(F)F)c3)nc(NC3CCCCC3)n2)cc1 Show InChI InChI=1S/C24H26F3N5O2/c1-33-19-12-10-17(11-13-19)28-21-15-22(32-23(31-21)30-16-6-3-2-4-7-16)29-18-8-5-9-20(14-18)34-24(25,26)27/h5,8-16H,2-4,6-7H2,1H3,(H3,28,29,30,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358662
(CHEMBL1922003)Show SMILES Cc1c(F)cccc1Nc1cc(nc(n1)N1CCCN(CC1)c1ncccc1C(F)(F)F)N1CCCCC1 Show InChI InChI=1S/C27H31F4N7/c1-19-21(28)9-5-10-22(19)33-23-18-24(36-12-3-2-4-13-36)35-26(34-23)38-15-7-14-37(16-17-38)25-20(27(29,30)31)8-6-11-32-25/h5-6,8-11,18H,2-4,7,12-17H2,1H3,(H,33,34,35) | PDB
Reactome pathway
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UniProtKB/SwissProt
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256666
((3S,6S,9S,12S)-3-benzyl-12-sec-butyl-6-((2S,3R)-3-...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)[C@H](C)[C@@H](C)O |r| Show InChI InChI=1S/C26H40N4O5/c1-7-15(4)21-25(34)28-20(14(2)3)24(33)30-22(16(5)17(6)31)26(35)27-19(23(32)29-21)13-18-11-9-8-10-12-18/h8-12,14-17,19-22,31H,7,13H2,1-6H3,(H,27,35)(H,28,34)(H,29,32)(H,30,33)/t15-,16+,17+,19-,20-,21-,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 574 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358667
(CHEMBL1922016)Show SMILES COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(n2)N2CCCCCC2)cc1 Show InChI InChI=1S/C24H28FN5O2/c1-31-19-10-7-17(8-11-19)27-24-28-22(26-18-9-12-21(32-2)20(25)15-18)16-23(29-24)30-13-5-3-4-6-14-30/h7-12,15-16H,3-6,13-14H2,1-2H3,(H2,26,27,28,29) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358655
(CHEMBL1921996)Show SMILES COc1ccc(Nc2cc(Nc3cccc(OC(F)F)c3)nc(NC3CCCCC3)n2)cc1 Show InChI InChI=1S/C24H27F2N5O2/c1-32-19-12-10-17(11-13-19)27-21-15-22(28-18-8-5-9-20(14-18)33-23(25)26)31-24(30-21)29-16-6-3-2-4-7-16/h5,8-16,23H,2-4,6-7H2,1H3,(H3,27,28,29,30,31) | PDB
Reactome pathway
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UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358678
(CHEMBL1922008)Show SMILES COc1ccc(Nc2nc(Nc3ccc(cc3)C(F)(F)F)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H24F3N5O/c1-32-19-11-9-18(10-12-19)28-22-29-20(15-21(30-22)31-13-3-2-4-14-31)27-17-7-5-16(6-8-17)23(24,25)26/h5-12,15H,2-4,13-14H2,1H3,(H2,27,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358653
(CHEMBL1921993)Show SMILES COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(n2)N2CCCC2)cc1 Show InChI InChI=1S/C22H25N5O2/c1-28-18-10-8-16(9-11-18)23-20-15-21(24-17-6-5-7-19(14-17)29-2)26-22(25-20)27-12-3-4-13-27/h5-11,14-15H,3-4,12-13H2,1-2H3,(H2,23,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 930 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358682
(CHEMBL1922012)Show SMILES COc1ccc(Nc2nc(Nc3ccc(F)cc3C)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C23H26FN5O/c1-16-14-17(24)6-11-20(16)26-21-15-22(29-12-4-3-5-13-29)28-23(27-21)25-18-7-9-19(30-2)10-8-18/h6-11,14-15H,3-5,12-13H2,1-2H3,(H2,25,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358656
(CHEMBL1921997)Show SMILES COc1ccc(Nc2cc(Nc3ccc(OC(F)(F)F)cc3)nc(NC3CCCCC3)n2)cc1 Show InChI InChI=1S/C24H26F3N5O2/c1-33-19-11-7-17(8-12-19)28-21-15-22(32-23(31-21)30-16-5-3-2-4-6-16)29-18-9-13-20(14-10-18)34-24(25,26)27/h7-16H,2-6H2,1H3,(H3,28,29,30,31,32) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358648
(CHEMBL1921902)Show InChI InChI=1S/C22H25N5O/c1-28-19-12-10-18(11-13-19)24-21-16-20(23-17-8-4-2-5-9-17)25-22(26-21)27-14-6-3-7-15-27/h2,4-5,8-13,16H,3,6-7,14-15H2,1H3,(H2,23,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358674
(CHEMBL1922004)Show SMILES COc1ccc(Nc2nc(Nc3ccc(C)cc3C)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C24H29N5O/c1-17-7-12-21(18(2)15-17)26-22-16-23(29-13-5-4-6-14-29)28-24(27-22)25-19-8-10-20(30-3)11-9-19/h7-12,15-16H,4-6,13-14H2,1-3H3,(H2,25,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM42052
(2-N,3-N-dimethyl-6,7-dinitroquinoxaline-2,3-diamin...)Show SMILES CNc1nc2cc(c(cc2nc1NC)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C10H10N6O4/c1-11-9-10(12-2)14-6-4-8(16(19)20)7(15(17)18)3-5(6)13-9/h3-4H,1-2H3,(H,11,13)(H,12,14) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2D21W05 |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358668
(CHEMBL1922019)Show SMILES COc1ccc(Nc2nc(Nc3ccc(OC)c(F)c3)cc(n2)N2CCCC(C)C2)cc1 Show InChI InChI=1S/C24H28FN5O2/c1-16-5-4-12-30(15-16)23-14-22(26-18-8-11-21(32-3)20(25)13-18)28-24(29-23)27-17-6-9-19(31-2)10-7-17/h6-11,13-14,16H,4-5,12,15H2,1-3H3,(H2,26,27,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358657
(CHEMBL1921998)Show SMILES COc1ccc(Nc2cc(Nc3cccc(OC)c3)nc(NC3CCCCC3)n2)cc1 Show InChI InChI=1S/C24H29N5O2/c1-30-20-13-11-18(12-14-20)25-22-16-23(26-19-9-6-10-21(15-19)31-2)29-24(28-22)27-17-7-4-3-5-8-17/h6,9-17H,3-5,7-8H2,1-2H3,(H3,25,26,27,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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UniChem
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| Article
PubMed
| n/a | n/a | 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358659
(CHEMBL1922000)Show SMILES COc1ccc(Nc2cc(nc(n2)N2CCCN(CC2)c2ncccc2C(F)(F)F)N2CCCCC2)cc1 Show InChI InChI=1S/C27H32F3N7O/c1-38-21-10-8-20(9-11-21)32-23-19-24(35-13-3-2-4-14-35)34-26(33-23)37-16-6-15-36(17-18-37)25-22(27(28,29)30)7-5-12-31-25/h5,7-12,19H,2-4,6,13-18H2,1H3,(H,32,33,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358681
(CHEMBL1922011)Show SMILES COc1ccc(Nc2nc(NCc3cccc(c3)C(F)(F)F)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C24H26F3N5O/c1-33-20-10-8-19(9-11-20)29-23-30-21(15-22(31-23)32-12-3-2-4-13-32)28-16-17-6-5-7-18(14-17)24(25,26)27/h5-11,14-15H,2-4,12-13,16H2,1H3,(H2,28,29,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358661
(CHEMBL1922002)Show SMILES COc1ccc(Nc2cc(nc(n2)N2CCCN(CC2)c2ncccc2C(F)(F)F)N2CCCCC2)cc1F Show InChI InChI=1S/C27H31F4N7O/c1-39-22-9-8-19(17-21(22)28)33-23-18-24(36-11-3-2-4-12-36)35-26(34-23)38-14-6-13-37(15-16-38)25-20(27(29,30)31)7-5-10-32-25/h5,7-10,17-18H,2-4,6,11-16H2,1H3,(H,33,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358660
(CHEMBL1922001)Show SMILES Cc1ccc(C)c(Nc2cc(nc(n2)N2CCCN(CC2)c2ncccc2C(F)(F)F)N2CCCCC2)c1 Show InChI InChI=1S/C28H34F3N7/c1-20-9-10-21(2)23(18-20)33-24-19-25(36-12-4-3-5-13-36)35-27(34-24)38-15-7-14-37(16-17-38)26-22(28(29,30)31)8-6-11-32-26/h6,8-11,18-19H,3-5,7,12-17H2,1-2H3,(H,33,34,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(RAT) | BDBM50256664
((S)-2-((2S,5S,8S,11S)-5-benzyl-8,11-di-sec-butyl-3...)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)[C@@H](C)CC)[C@H](CS(O)(=O)=O)C(C)=O |r| Show InChI InChI=1S/C27H40N4O8S/c1-6-15(3)21-25(34)30-22(16(4)7-2)26(35)31-23(19(17(5)32)14-40(37,38)39)27(36)28-20(24(33)29-21)13-18-11-9-8-10-12-18/h8-12,15-16,19-23H,6-7,13-14H2,1-5H3,(H,28,36)(H,29,33)(H,30,34)(H,31,35)(H,37,38,39)/t15-,16-,19+,20-,21-,22-,23-/m0/s1 | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of [3H]glycine uptake at rat glycine transporter 2 expressed in african green monkey COS7 cells |
Bioorg Med Chem Lett 18: 6321-3 (2008)
Article DOI: 10.1016/j.bmcl.2008.10.104
BindingDB Entry DOI: 10.7270/Q2BZ65WC |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358685
(CHEMBL1922017)Show SMILES CCN(CC)c1cc(Nc2ccc(OC)c(F)c2)nc(Nc2ccc(OC)cc2)n1 Show InChI InChI=1S/C22H26FN5O2/c1-5-28(6-2)21-14-20(24-16-9-12-19(30-4)18(23)13-16)26-22(27-21)25-15-7-10-17(29-3)11-8-15/h7-14H,5-6H2,1-4H3,(H2,24,25,26,27) | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358664
(CHEMBL1921988)Show SMILES FC(F)Oc1ccc(Nc2cc(Nc3ccccc3)nc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C22H23F2N5O/c23-21(24)30-18-11-9-17(10-12-18)26-20-15-19(25-16-7-3-1-4-8-16)27-22(28-20)29-13-5-2-6-14-29/h1,3-4,7-12,15,21H,2,5-6,13-14H2,(H2,25,26,27,28) | PDB
Reactome pathway
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UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358652
(CHEMBL1921992)Show SMILES COc1ccc(Nc2cc(nc(n2)N2CCCC2)N2CCN(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H30N6O/c1-32-22-11-9-20(10-12-22)26-23-19-24(28-25(27-23)31-13-5-6-14-31)30-17-15-29(16-18-30)21-7-3-2-4-8-21/h2-4,7-12,19H,5-6,13-18H2,1H3,(H,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358665
(CHEMBL1921990)Show SMILES C(Nc1cc(Nc2ccccc2)nc(n1)N1CCCCC1)c1ccc2OCOc2c1 Show InChI InChI=1S/C23H25N5O2/c1-3-7-18(8-4-1)25-22-14-21(26-23(27-22)28-11-5-2-6-12-28)24-15-17-9-10-19-20(13-17)30-16-29-19/h1,3-4,7-10,13-14H,2,5-6,11-12,15-16H2,(H2,24,25,26,27) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358650
(CHEMBL1921989)Show SMILES FC(F)Oc1cccc(Nc2cc(Nc3ccccc3)nc(n2)N2CCCCC2)c1 Show InChI InChI=1S/C22H23F2N5O/c23-21(24)30-18-11-7-10-17(14-18)26-20-15-19(25-16-8-3-1-4-9-16)27-22(28-20)29-12-5-2-6-13-29/h1,3-4,7-11,14-15,21H,2,5-6,12-13H2,(H2,25,26,27,28) | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358684
(CHEMBL1922014)Show SMILES COc1ccc(Nc2nc(Nc3ccc(F)c(Cl)c3)cc(n2)N2CCCCC2)cc1 Show InChI InChI=1S/C22H23ClFN5O/c1-30-17-8-5-15(6-9-17)26-22-27-20(25-16-7-10-19(24)18(23)13-16)14-21(28-22)29-11-3-2-4-12-29/h5-10,13-14H,2-4,11-12H2,1H3,(H2,25,26,27,28) | PDB
Reactome pathway
KEGG
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| CHEMBL
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358663
(CHEMBL1921901)Show SMILES Cc1ccc(C)c(Nc2cc(Nc3ccccc3)nc(n2)N2CCCCC2)c1 Show InChI InChI=1S/C23H27N5/c1-17-11-12-18(2)20(15-17)25-22-16-21(24-19-9-5-3-6-10-19)26-23(27-22)28-13-7-4-8-14-28/h3,5-6,9-12,15-16H,4,7-8,13-14H2,1-2H3,(H2,24,25,26,27) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50007082
((E)-2-methoxy-4-(2-nitrovinyl)phenol | 2-Methoxy-4...)Show InChI InChI=1S/C9H9NO4/c1-14-9-6-7(2-3-8(9)11)4-5-10(12)13/h2-6,11H,1H3/b5-4+ | PDB
Reactome pathway
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MCE
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PC sid
UniChem
Similars
| PCBioAssay
| n/a | n/a | >4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2D21W05 |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM42060
(4,5-bis(chloranyl)-2-[2-(4-naphthalen-2-ylsulfonyl...)Show SMILES Clc1cnn(CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc3ccccc3c2)c(=O)c1Cl Show InChI InChI=1S/C20H18Cl2N4O4S/c21-17-12-23-26(20(28)19(17)22)13-18(27)24-7-9-25(10-8-24)31(29,30)16-6-5-14-3-1-2-4-15(14)11-16/h1-6,11-12H,7-10,13H2 | PDB
Reactome pathway
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PC sid
UniChem
| PCBioAssay
| n/a | n/a | 5.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2D21W05 |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358649
(CHEMBL1921903)Show SMILES FC(F)(F)Oc1cccc(Nc2cc(Nc3ccccc3)nc(n2)N2CCCCC2)c1 Show InChI InChI=1S/C22H22F3N5O/c23-22(24,25)31-18-11-7-10-17(14-18)27-20-15-19(26-16-8-3-1-4-9-16)28-21(29-20)30-12-5-2-6-13-30/h1,3-4,7-11,14-15H,2,5-6,12-13H2,(H2,26,27,28,29) | PDB
Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM42053
(MLS000573994 | N-[4-[[(E)-3-(4-chlorophenyl)acrylo...)Show SMILES Clc1ccc(C=CC(=O)NC(=S)Nc2ccc(NC(=O)c3ccco3)cc2)cc1 |w:5.4| Show InChI InChI=1S/C21H16ClN3O3S/c22-15-6-3-14(4-7-15)5-12-19(26)25-21(29)24-17-10-8-16(9-11-17)23-20(27)18-2-1-13-28-18/h1-13H,(H,23,27)(H2,24,25,26,29) | PDB
Reactome pathway
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PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 6.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2D21W05 |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM42069
(2-acetamido-4,5-dinitro-benzoic acid ethyl ester |...)Show SMILES CCOC(=O)c1cc(c(cc1NC(C)=O)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C11H11N3O7/c1-3-21-11(16)7-4-9(13(17)18)10(14(19)20)5-8(7)12-6(2)15/h4-5H,3H2,1-2H3,(H,12,15) | PDB
Reactome pathway
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| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 7.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute (TSRI) Assay Provid... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2W094B7 |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM42061
(2-(4,5-dichloro-6-keto-pyridazin-1-yl)-N-[2-(2-eth...)Show SMILES CCc1ccccc1NC(=O)CN(C)C(=O)Cn1ncc(Cl)c(Cl)c1=O Show InChI InChI=1S/C17H18Cl2N4O3/c1-3-11-6-4-5-7-13(11)21-14(24)9-22(2)15(25)10-23-17(26)16(19)12(18)8-20-23/h4-8H,3,9-10H2,1-2H3,(H,21,24) | PDB
Reactome pathway
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PC sid
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Similars
| PCBioAssay
| n/a | n/a | 7.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Florida Research Institute, TSRI Assay... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2D21W05 |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358666
(CHEMBL1921994)Show SMILES COc1ccc(Nc2cc(Nc3ccc(OC)cc3)nc(n2)N2CCCC2)cc1 Show InChI InChI=1S/C22H25N5O2/c1-28-18-9-5-16(6-10-18)23-20-15-21(24-17-7-11-19(29-2)12-8-17)26-22(25-20)27-13-3-4-14-27/h5-12,15H,3-4,13-14H2,1-2H3,(H2,23,24,25,26) | PDB
Reactome pathway
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UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
Galanin receptor type 2
(Homo sapiens (Human)) | BDBM50358651
(CHEMBL1921991)Show SMILES COc1ccc(Nc2cc(Nc3ccccc3)nc(n2)N2CCCCC2)cc1F Show InChI InChI=1S/C22H24FN5O/c1-29-19-11-10-17(14-18(19)23)25-21-15-20(24-16-8-4-2-5-9-16)26-22(27-21)28-12-6-3-7-13-28/h2,4-5,8-11,14-15H,3,6-7,12-13H2,1H3,(H2,24,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Displacement of [125I]galanin from GalR2 by gamma counting |
Bioorg Med Chem Lett 21: 7210-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.09.033
BindingDB Entry DOI: 10.7270/Q2JS9QVT |
More data for this
Ligand-Target Pair | |
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