Compile Data Set for Download or QSAR

Found 112 hits of ec50 for UniProtKB: P06536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (RAT)	BDBM50153512 ((9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydr...) Show SMILES C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(O)=O |c:11,t:7| Show InChI InChI=1S/C21H27FO5/c1-11-8-15-14-5-4-12-9-13(23)6-7-18(12,2)20(14,22)16(24)10-19(15,3)21(11,27)17(25)26/h6-7,9,11,14-16,24,27H,4-5,8,10H2,1-3H3,(H,25,26)/t11-,14?,15+,16+,18+,19+,20+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153512 ((9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydr...) Show SMILES C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(O)=O |c:11,t:7| Show InChI InChI=1S/C21H27FO5/c1-11-8-15-14-5-4-12-9-13(23)6-7-18(12,2)20(14,22)16(24)10-19(15,3)21(11,27)17(25)26/h6-7,9,11,14-16,24,27H,4-5,8,10H2,1-3H3,(H,25,26)/t11-,14?,15+,16+,18+,19+,20+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153512 ((9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydr...) Show SMILES C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(O)=O |c:11,t:7| Show InChI InChI=1S/C21H27FO5/c1-11-8-15-14-5-4-12-9-13(23)6-7-18(12,2)20(14,22)16(24)10-19(15,3)21(11,27)17(25)26/h6-7,9,11,14-16,24,27H,4-5,8,10H2,1-3H3,(H,25,26)/t11-,14?,15+,16+,18+,19+,20+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50577695 (CHEMBL4853394) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(C)cc1)C(C)(C)O |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.398	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50594604 (CHEMBL5173367) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@H](O)C1CC1 |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00299 BindingDB Entry DOI: 10.7270/Q2N87FSM
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50354849 (CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...) Show SMILES CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF |r,c:18,t:14| Show InChI InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.760	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosine amino transferase				Bioorg Med Chem Lett 21: 6343-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.108 BindingDB Entry DOI: 10.7270/Q2FF3SRN
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50594607 (CHEMBL5185246) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@H](O)c1ccc2ccccc2c1 |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00299 BindingDB Entry DOI: 10.7270/Q2N87FSM
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153501 ((4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(F)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H24F2N2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153508 (Benzo[b]thiophen-3-yl-[(4aR,5S)-1-(4-fluoro-phenyl...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1csc2ccccc12)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C27H25FN2OS/c1-27-14-17-15-29-30(20-11-9-19(28)10-12-20)24(17)13-18(27)5-4-7-23(27)26(31)22-16-32-25-8-3-2-6-21(22)25/h2-3,6,8-13,15-16,23,26,31H,4-5,7,14H2,1H3/t23-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM18207 ((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...) Show SMILES [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |c:28,t:24| Show InChI InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (RAT)	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Forschungszentrum Dresden-Rossendorf e.V. Curated by ChEMBL					Assay Description Binding affinity to rat glucocorticoid receptor				Bioorg Med Chem Lett 17: 4035-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.094 BindingDB Entry DOI: 10.7270/Q25X2CRN
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (RAT)	BDBM50153504 (CHEMBL366093 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES COc1cccc(c1)C(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:15| Show InChI InChI=1S/C26H27FN2O2/c1-26-15-18-16-28-29(21-11-9-20(27)10-12-21)24(18)14-19(26)6-4-8-23(26)25(30)17-5-3-7-22(13-17)31-2/h3,5,7,9-14,16,23,25,30H,4,6,8,15H2,1-2H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153509 (CHEMBL181601 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O/c1-25-15-18-16-27-28(21-12-10-20(26)11-13-21)23(18)14-19(25)8-5-9-22(25)24(29)17-6-3-2-4-7-17/h2-4,6-7,10-14,16,22,24,29H,5,8-9,15H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153503 (3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1cccc(O)c1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O2/c1-25-14-17-15-27-28(20-10-8-19(26)9-11-20)23(17)13-18(25)5-3-7-22(25)24(30)16-4-2-6-21(29)12-16/h2,4,6,8-13,15,22,24,29-30H,3,5,7,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153502 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES CCCCC(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:10| Show InChI InChI=1S/C23H29FN2O/c1-3-4-8-22(27)20-7-5-6-17-13-21-16(14-23(17,20)2)15-25-26(21)19-11-9-18(24)10-12-19/h9-13,15,20,22,27H,3-8,14H2,1-2H3/t20-,22?,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153503 (3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1cccc(O)c1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O2/c1-25-14-17-15-27-28(20-10-8-19(26)9-11-20)23(17)13-18(25)5-3-7-22(25)24(30)16-4-2-6-21(29)12-16/h2,4,6,8-13,15,22,24,29-30H,3,5,7,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153503 (3-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1cccc(O)c1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O2/c1-25-14-17-15-27-28(20-10-8-19(26)9-11-20)23(17)13-18(25)5-3-7-22(25)24(30)16-4-2-6-21(29)12-16/h2,4,6,8-13,15,22,24,29-30H,3,5,7,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153501 ((4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(F)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H24F2N2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153513 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)CCc1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C27H29FN2O/c1-27-17-20-18-29-30(23-13-11-22(28)12-14-23)25(20)16-21(27)8-5-9-24(27)26(31)15-10-19-6-3-2-4-7-19/h2-4,6-7,11-14,16,18,24,26,31H,5,8-10,15,17H2,1H3/t24-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153507 (CHEMBL186948 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc2ccccc2c1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C29H27FN2O/c1-29-17-22-18-31-32(25-13-11-24(30)12-14-25)27(22)16-23(29)7-4-8-26(29)28(33)21-10-9-19-5-2-3-6-20(19)15-21/h2-3,5-6,9-16,18,26,28,33H,4,7-8,17H2,1H3/t26-,28?,29+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153506 ((4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(Cl)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H24ClFN2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153509 (CHEMBL181601 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O/c1-25-15-18-16-27-28(21-12-10-20(26)11-13-21)23(18)14-19(25)8-5-9-22(25)24(29)17-6-3-2-4-7-17/h2-4,6-7,10-14,16,22,24,29H,5,8-9,15H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153519 (CHEMBL186954 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES Cc1ccc(cc1)C(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C26H27FN2O/c1-17-6-8-18(9-7-17)25(30)23-5-3-4-20-14-24-19(15-26(20,23)2)16-28-29(24)22-12-10-21(27)11-13-22/h6-14,16,23,25,30H,3-5,15H2,1-2H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM18207 ((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...) Show SMILES [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |c:28,t:24| Show InChI InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00299 BindingDB Entry DOI: 10.7270/Q2N87FSM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (RAT)	BDBM50153509 (CHEMBL181601 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O/c1-25-15-18-16-27-28(21-12-10-20(26)11-13-21)23(18)14-19(25)8-5-9-22(25)24(29)17-6-3-2-4-7-17/h2-4,6-7,10-14,16,22,24,29H,5,8-9,15H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153506 ((4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(Cl)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H24ClFN2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153519 (CHEMBL186954 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES Cc1ccc(cc1)C(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C26H27FN2O/c1-17-6-8-18(9-7-17)25(30)23-5-3-4-20-14-24-19(15-26(20,23)2)16-28-29(24)22-12-10-21(27)11-13-22/h6-14,16,23,25,30H,3-5,15H2,1-2H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153515 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES CCCCCCCCC(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C27H37FN2O/c1-3-4-5-6-7-8-12-26(31)24-11-9-10-21-17-25-20(18-27(21,24)2)19-29-30(25)23-15-13-22(28)14-16-23/h13-17,19,24,26,31H,3-12,18H2,1-2H3/t24-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50577692 (CHEMBL4872787) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@@](C)(O)c1ccsc1 |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50577690 (CHEMBL4855992) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@](C)(O)c1ccccc1 |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153504 (CHEMBL366093 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES COc1cccc(c1)C(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:15| Show InChI InChI=1S/C26H27FN2O2/c1-26-15-18-16-28-29(21-11-9-20(27)10-12-21)24(18)14-19(26)6-4-8-23(26)25(30)17-5-3-7-22(13-17)31-2/h3,5,7,9-14,16,23,25,30H,4,6,8,15H2,1-2H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153515 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES CCCCCCCCC(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C27H37FN2O/c1-3-4-5-6-7-8-12-26(31)24-11-9-10-21-17-25-20(18-27(21,24)2)19-29-30(25)23-15-13-22(28)14-16-23/h13-17,19,24,26,31H,3-12,18H2,1-2H3/t24-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153502 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES CCCCC(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:10| Show InChI InChI=1S/C23H29FN2O/c1-3-4-8-22(27)20-7-5-6-17-13-21-16(14-23(17,20)2)15-25-26(21)19-11-9-18(24)10-12-19/h9-13,15,20,22,27H,3-8,14H2,1-2H3/t20-,22?,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153515 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES CCCCCCCCC(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C27H37FN2O/c1-3-4-5-6-7-8-12-26(31)24-11-9-10-21-17-25-20(18-27(21,24)2)19-29-30(25)23-15-13-22(28)14-16-23/h13-17,19,24,26,31H,3-12,18H2,1-2H3/t24-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50577691 (CHEMBL4850526) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@](C)(O)c1cc(F)c(F)c(OC)c1 |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153513 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)CCc1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C27H29FN2O/c1-27-17-20-18-29-30(23-13-11-22(28)12-14-23)25(20)16-21(27)8-5-9-24(27)26(31)15-10-19-6-3-2-4-7-19/h2-4,6-7,11-14,16,18,24,26,31H,5,8-10,15,17H2,1H3/t24-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50577710 (CHEMBL4857046) Show SMILES [H][C@@]1(CCCC2=Cc3c(CC12)cnn3-c1ccc(OC)cc1)[C@@H](O)c1cc(F)c(F)c(OC)c1 |r,t:5| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50107347 ((+)5-Allyl-10-methoxy-2,2,4-trimethyl-2,5-dihydro-...) Show SMILES COc1cccc2OC(CC=C)c3c(ccc4NC(C)(C)C=C(C)c34)-c12 |t:21| Show InChI InChI=1S/C23H25NO2/c1-6-8-18-22-15(21-17(25-5)9-7-10-19(21)26-18)11-12-16-20(22)14(2)13-23(3,4)24-16/h6-7,9-13,18,24H,1,8H2,2-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
Forschungszentrum Dresden-Rossendorf e.V. Curated by ChEMBL					Assay Description Binding affinity to rat glucocorticoid receptor				Bioorg Med Chem Lett 17: 4035-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.094 BindingDB Entry DOI: 10.7270/Q25X2CRN
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153519 (CHEMBL186954 | [(4aR,5S)-1-(4-Fluoro-phenyl)-4a-me...) Show SMILES Cc1ccc(cc1)C(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:14| Show InChI InChI=1S/C26H27FN2O/c1-17-6-8-18(9-7-17)25(30)23-5-3-4-20-14-24-19(15-26(20,23)2)16-28-29(24)22-12-10-21(27)11-13-22/h6-14,16,23,25,30H,3-5,15H2,1-2H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153502 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES CCCCC(O)[C@H]1CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1 |t:10| Show InChI InChI=1S/C23H29FN2O/c1-3-4-8-22(27)20-7-5-6-17-13-21-16(14-23(17,20)2)15-25-26(21)19-11-9-18(24)10-12-19/h9-13,15,20,22,27H,3-8,14H2,1-2H3/t20-,22?,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153501 ((4-Fluoro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(F)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H24F2N2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153511 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)Cc1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C26H27FN2O/c1-26-16-19-17-28-29(22-12-10-21(27)11-13-22)24(19)15-20(26)8-5-9-23(26)25(30)14-18-6-3-2-4-7-18/h2-4,6-7,10-13,15,17,23,25,30H,5,8-9,14,16H2,1H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153506 ((4-Chloro-phenyl)-[(4aR,5S)-1-(4-fluoro-phenyl)-4a...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(Cl)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H24ClFN2O/c1-25-14-17-15-28-29(21-11-9-20(27)10-12-21)23(17)13-18(25)3-2-4-22(25)24(30)16-5-7-19(26)8-6-16/h5-13,15,22,24,30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153511 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)Cc1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C26H27FN2O/c1-26-16-19-17-28-29(22-12-10-21(27)11-13-22)24(19)15-20(26)8-5-9-23(26)25(30)14-18-6-3-2-4-7-18/h2-4,6-7,10-13,15,17,23,25,30H,5,8-9,14,16H2,1H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153513 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)CCc1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C27H29FN2O/c1-27-17-20-18-29-30(23-13-11-22(28)12-14-23)25(20)16-21(27)8-5-9-24(27)26(31)15-10-19-6-3-2-4-7-19/h2-4,6-7,11-14,16,18,24,26,31H,5,8-10,15,17H2,1H3/t24-,26?,27+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Effective concentration against MMTV in transactivation assay in U2OS cells expressing rat GR				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153514 (4-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(O)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O2/c1-25-14-17-15-27-28(20-9-7-19(26)8-10-20)23(17)13-18(25)3-2-4-22(25)24(30)16-5-11-21(29)12-6-16/h5-13,15,22,24,29-30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of NFkB-luciferase reporter activity in TPA stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153514 (4-{[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)c1ccc(O)cc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C25H25FN2O2/c1-25-14-17-15-27-28(20-9-7-19(26)8-10-20)23(17)13-18(25)3-2-4-22(25)24(30)16-5-11-21(29)12-6-16/h5-13,15,22,24,29-30H,2-4,14H2,1H3/t22-,24?,25+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM19201 ((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...) Show SMILES [H][C@@]1(CCCC2=Cc3c(C[C@]12C)cnn3-c1ccc(F)cc1)[C@](C)(O)c1ccc(F)cc1 |r,t:5| Show InChI InChI=1S/C26H26F2N2O/c1-25-15-17-16-29-30(22-12-10-21(28)11-13-22)23(17)14-19(25)4-3-5-24(25)26(2,31)18-6-8-20(27)9-7-18/h6-14,16,24,31H,3-5,15H2,1-2H3/t24-,25-,26+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at glucocorticoid receptor in rat INS-1 832/13 cells transfected with 3XGRE-promoter luciferase plasmid construct assessed as induct...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00379 BindingDB Entry DOI: 10.7270/Q2VM4H3N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50153511 (1-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5,6...) Show SMILES C[C@]12Cc3cnn(c3C=C1CCC[C@@H]2C(O)Cc1ccccc1)-c1ccc(F)cc1 |c:9| Show InChI InChI=1S/C26H27FN2O/c1-26-16-19-17-28-29(22-12-10-21(27)11-13-22)24(19)15-20(26)8-5-9-23(26)25(30)14-18-6-3-2-4-7-18/h2-4,6-7,10-13,15,17,23,25,30H,5,8-9,14,16H2,1H3/t23-,25?,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
University of California--San Francisco Curated by ChEMBL					Assay Description Repression of AP1-luciferase reporter activity in TPA-stimulated U2OS cells expressing rat glucocorticoid receptor				Bioorg Med Chem Lett 14: 5199-203 (2004) Article DOI: 10.1016/j.bmcl.2004.07.052 BindingDB Entry DOI: 10.7270/Q2G73D65
					More data for this Ligand-Target Pair
Glucocorticoid receptor (RAT)	BDBM50357083 (CHEMBL1917414) Show SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(OC(=O)c1ccco1)C(=O)CSc1nc2ccccc2s1 |r,c:13,t:9| Show InChI InChI=1S/C33H33NO6S2/c1-31-13-11-20(35)16-19(31)9-10-21-22-12-14-33(32(22,2)17-24(36)28(21)31,40-29(38)25-7-5-15-39-25)27(37)18-41-30-34-23-6-3-4-8-26(23)42-30/h3-8,11,13,15-16,21-22,24,28,36H,9-10,12,14,17-18H2,1-2H3/t21-,22-,24-,28+,31-,32-,33-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18.7	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosine amino transferase				Bioorg Med Chem Lett 21: 6343-7 (2011) Article DOI: 10.1016/j.bmcl.2011.08.108 BindingDB Entry DOI: 10.7270/Q2FF3SRN
					More data for this Ligand-Target Pair

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