BindingDB PrimarySearch

Found 142 hits of ki data for polymerid = 49000611
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494356 (CHEMBL3088070) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	3.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM17662 ((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...) Show SMILES Cc1o[nH]c(=O)c1C[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	16.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) Show SMILES Cc1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells				J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060628 ((S)-2-Amino-3-(6-chloro-3,5-dioxo-4,5-dihydro-3H-[...) Show SMILES N[C@@H](Cn1nc(Cl)c(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060630 ((S)-2-Amino-3-(6-bromo-3,5-dioxo-4,5-dihydro-3H-[1...) Show SMILES N[C@@H](Cn1nc(Br)c(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060635 ((S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060632 ((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) Show SMILES CCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060629 ((S)-2-Amino-3-(6-iodo-3,5-dioxo-4,5-dihydro-3H-[1,...) Show SMILES N[C@@H](Cn1nc(I)c(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060636 ((S)-2-Amino-3-(5-bromo-2,4-dioxo-3,4-dihydro-2H-py...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM17662 ((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...) Show SMILES Cc1o[nH]c(=O)c1C[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50027828 ((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...) Show SMILES [O-]C(=O)C1[NH2+]CCc2c1o[nH]c2=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from GluA2-S1S2 receptor				J Med Chem 53: 8354-8361 (2010) Article DOI: 10.1021/jm101218a BindingDB Entry DOI: 10.7270/Q20Z73HW
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060631 ((S)-2-Amino-3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-py...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	115	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060627 ((S)-2-Amino-3-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly Curated by ChEMBL					Assay Description Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells				J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
Centro de Investigación Lilly Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50373889 (CHEMBL402444) Show SMILES N[C@H](Cc1ns[nH]c1=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	234	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity at iGluR2o(R) receptor expressed in sf9 cells by radioligand binding assay				J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50017244 ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) Show SMILES NC(Cc1o[nH]c(=O)c1Br)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells				J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50373890 (CHEMBL429594) Show SMILES N[C@@H](Cc1ns[nH]c1=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	273	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity at iGluR2o(R) receptor expressed in sf9 cells by radioligand binding assay				J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50373890 (CHEMBL429594) Show SMILES N[C@@H](Cc1ns[nH]c1=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	323	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity at iGluR2 receptor S1S2J domain expressed in sf9 cells by radioligand binding assay				J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50128264 ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) Show SMILES NC(Cc1o[nH]c(=O)c1Cl)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells				J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060633 ((S)-2-Amino-3-(6-methyl-3,5-dioxo-4,5-dihydro-3H-[...) Show SMILES Cc1nn(C[C@H](N)C(O)=O)c(=O)[nH]c1=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	372	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494351 (CHEMBL3088060) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50060634 ((S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]tri...) Show SMILES N[C@@H](Cn1ncc(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	461	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50373889 (CHEMBL402444) Show SMILES N[C@H](Cc1ns[nH]c1=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	531	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Binding affinity at iGluR2 receptor S1S2J domain expressed in sf9 cells by radioligand binding assay				J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86750 (LY 302679 \| LY-302679) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 318: 772-81 (2006) Article DOI: 10.1124/jpet.106.101428 BindingDB Entry DOI: 10.7270/Q2NP230D
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM17661 ((2S)-2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimi...) Show SMILES N[C@@H](Cn1ccc(=O)[nH]c1=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	898	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Ltd Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cells				Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB
Eli Lilly and Company Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM26431 ((2R)-2-aminopentanedioic acid \| CHEMBL76232 \| D-Gl...) Show SMILES N[C@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, S.A. Curated by ChEMBL					Assay Description Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 2 in HK293 cells using [3H]-AMPA as radioligand				J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB
Lilly, S.A. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM17657 ((2S)-2-aminopentanedioic acid \| (S)-Glu \| D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells				J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) Show SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494348 (CHEMBL3088069) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494362 (CHEMBL3088063) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494347 (CHEMBL3088071) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86751 (CHEMBL14935 \| LY 293558 \| LY-293558) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly Curated by ChEMBL					Assay Description Inhibition of [3H]-AMPA binding to human Ionontropic glutamate receptor 2				J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
Centro de Investigación Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50142614 (CHEMBL3758336) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting method				J Med Chem 59: 448-61 (2016) Article DOI: 10.1021/acs.jmedchem.5b01666 BindingDB Entry DOI: 10.7270/Q2VQ34JK
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494350 (CHEMBL3088064) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494352 (CHEMBL3088059) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells				J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494341 (LY-293,558 \| LY-293558 \| NGX-424 \| TEZAMPANEL) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50267948 (CHEMBL4097333) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Annunziata, 98168 Messina, Italy. Curated by ChEMBL					Assay Description Antagonist activity at closed state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced curre...				Bioorg Med Chem 25: 3631-3637 (2017) Article DOI: 10.1016/j.bmc.2017.05.036 BindingDB Entry DOI: 10.7270/Q2TF00T9
					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50355329 (CHEMBL1835336) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article PubMed	3.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from recombinant GluA2 S1S2J soluble ligand binding domain				J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86751 (CHEMBL14935 \| LY 293558 \| LY-293558) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 318: 772-81 (2006) Article DOI: 10.1124/jpet.106.101428 BindingDB Entry DOI: 10.7270/Q2NP230D
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86751 (CHEMBL14935 \| LY 293558 \| LY-293558) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Binding affinity to GluR2				J Med Chem 53: 5367-82 (2010) Article DOI: 10.1021/jm901688m BindingDB Entry DOI: 10.7270/Q2FX79NV
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM86751 (CHEMBL14935 \| LY 293558 \| LY-293558) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2				J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494067 (CHEMBL2440517) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Binding affinity to GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50494349 (CHEMBL3088066) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaci�n Lilly Curated by ChEMBL					Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)				Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW
Centro de Investigaci�n Lilly Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50091477 ((S)-2-Amino-4-cyclopentylidene-pentanedioic acid \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Ltd Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cells				Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB
Eli Lilly and Company Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor 2 (Homo sapiens (Human))	BDBM50091474 ((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...) Show SMILES CC(C)\C=C(/C[C@H](N)C(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Ltd Curated by ChEMBL					Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cells				Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB
Eli Lilly and Company Ltd Curated by ChEMBL					More data for this Ligand-Target Pair

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