Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494356 (CHEMBL3088070) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50166288 ((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 3.89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells | J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM17662 ((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 16.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells | J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50002370 ((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060628 ((S)-2-Amino-3-(6-chloro-3,5-dioxo-4,5-dihydro-3H-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060630 ((S)-2-Amino-3-(6-bromo-3,5-dioxo-4,5-dihydro-3H-[1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060635 ((S)-2-Amino-3-(5-fluoro-2,4-dioxo-3,4-dihydro-2H-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060632 ((S)-2-Amino-3-(5-chloro-2,4-dioxo-3,4-dihydro-2H-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50166286 ((RS)-2-amino-3-[3-hydroxy-5-(2-ethyl-2H-5-tetrazol...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 80.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells | J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060629 ((S)-2-Amino-3-(6-iodo-3,5-dioxo-4,5-dihydro-3H-[1,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060636 ((S)-2-Amino-3-(5-bromo-2,4-dioxo-3,4-dihydro-2H-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM17662 ((2S)-2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50027828 ((7S)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from GluA2-S1S2 receptor | J Med Chem 53: 8354-8361 (2010) Article DOI: 10.1021/jm101218a BindingDB Entry DOI: 10.7270/Q20Z73HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060631 ((S)-2-Amino-3-(5-nitro-2,4-dioxo-3,4-dihydro-2H-py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060627 ((S)-2-Amino-3-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells | J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50373889 (CHEMBL402444) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 234 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Binding affinity at iGluR2o(R) receptor expressed in sf9 cells by radioligand binding assay | J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50017244 ((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2 | J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50373890 (CHEMBL429594) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 273 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Binding affinity at iGluR2o(R) receptor expressed in sf9 cells by radioligand binding assay | J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50373890 (CHEMBL429594) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 323 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Binding affinity at iGluR2 receptor S1S2J domain expressed in sf9 cells by radioligand binding assay | J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50128264 ((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 370 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity of compound was determined towards cloned Ionotropic glutamate receptor AMPA 2 (GluR2) expressed in Sf 9 insect cells | J Med Chem 46: 2246-9 (2003) Article DOI: 10.1021/jm020588f BindingDB Entry DOI: 10.7270/Q26T0M06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060633 ((S)-2-Amino-3-(6-methyl-3,5-dioxo-4,5-dihydro-3H-[...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 372 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494351 (CHEMBL3088060) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50060634 ((S)-2-Amino-3-(3,5-dioxo-4,5-dihydro-3H-[1,2,4]tri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 461 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50373889 (CHEMBL402444) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 531 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Binding affinity at iGluR2 receptor S1S2J domain expressed in sf9 cells by radioligand binding assay | J Med Chem 51: 1459-63 (2008) Article DOI: 10.1021/jm701126w BindingDB Entry DOI: 10.7270/Q2S75H6Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM86750 (LY 302679 | LY-302679) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by PDSP Ki Database | J Pharmacol Exp Ther 318: 772-81 (2006) Article DOI: 10.1124/jpet.106.101428 BindingDB Entry DOI: 10.7270/Q2NP230D | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM17661 ((2S)-2-amino-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 898 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cells | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM26431 ((2R)-2-aminopentanedioic acid | CHEMBL76232 | D-Gl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly, S.A. Curated by ChEMBL | Assay Description Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 2 in HK293 cells using [3H]-AMPA as radioligand | J Med Chem 43: 1958-68 (2000) BindingDB Entry DOI: 10.7270/Q2FX78QB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 940 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cells | J Med Chem 40: 3645-50 (1997) Article DOI: 10.1021/jm9702387 BindingDB Entry DOI: 10.7270/Q28G8MCB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50166285 ((RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells | J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494348 (CHEMBL3088069) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494362 (CHEMBL3088063) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494347 (CHEMBL3088071) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM86751 (CHEMBL14935 | LY 293558 | LY-293558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly Curated by ChEMBL | Assay Description Inhibition of [3H]-AMPA binding to human Ionontropic glutamate receptor 2 | J Med Chem 48: 4200-3 (2005) Article DOI: 10.1021/jm0491952 BindingDB Entry DOI: 10.7270/Q2HQ3ZDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50142614 (CHEMBL3758336) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from GluA2 LBD (unknown origin) incubated for 2 hrs by liquid scintillation counting method | J Med Chem 59: 448-61 (2016) Article DOI: 10.1021/acs.jmedchem.5b01666 BindingDB Entry DOI: 10.7270/Q2VQ34JK | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494350 (CHEMBL3088064) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494352 (CHEMBL3088059) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50166287 ((RS)-2-amino-3-[3-hydroxy-5-(2-isopropyl-2H-5-tetr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Danish University of Pharmaceutical Sciences Curated by ChEMBL | Assay Description Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cells | J Med Chem 48: 3438-42 (2005) Article DOI: 10.1021/jm050014l BindingDB Entry DOI: 10.7270/Q2H70FBJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494341 (LY-293,558 | LY-293558 | NGX-424 | TEZAMPANEL) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50267948 (CHEMBL4097333) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Annunziata, 98168 Messina, Italy. Curated by ChEMBL | Assay Description Antagonist activity at closed state of GluA2Qflip isoform (unknown origin) expressed in HEK293 cells assessed as reduction in glutamate-induced curre... | Bioorg Med Chem 25: 3631-3637 (2017) Article DOI: 10.1016/j.bmc.2017.05.036 BindingDB Entry DOI: 10.7270/Q2TF00T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50355329 (CHEMBL1835336) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 3.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from recombinant GluA2 S1S2J soluble ligand binding domain | J Med Chem 54: 7289-98 (2011) Article DOI: 10.1021/jm200862h BindingDB Entry DOI: 10.7270/Q2QC03WT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM86751 (CHEMBL14935 | LY 293558 | LY-293558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by PDSP Ki Database | J Pharmacol Exp Ther 318: 772-81 (2006) Article DOI: 10.1124/jpet.106.101428 BindingDB Entry DOI: 10.7270/Q2NP230D | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM86751 (CHEMBL14935 | LY 293558 | LY-293558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma AG Curated by ChEMBL | Assay Description Binding affinity to GluR2 | J Med Chem 53: 5367-82 (2010) Article DOI: 10.1021/jm901688m BindingDB Entry DOI: 10.7270/Q2FX79NV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM86751 (CHEMBL14935 | LY 293558 | LY-293558) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2 | J Med Chem 45: 4383-6 (2002) BindingDB Entry DOI: 10.7270/Q2XP75N4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494067 (CHEMBL2440517) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Binding affinity to GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6459-62 (2013) Article DOI: 10.1016/j.bmcl.2013.09.046 BindingDB Entry DOI: 10.7270/Q2862KDB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50494349 (CHEMBL3088066) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin) | Bioorg Med Chem Lett 23: 6463-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.045 BindingDB Entry DOI: 10.7270/Q2XS5ZBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50091477 ((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cells | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Homo sapiens (Human)) | BDBM50091474 ((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Ltd Curated by ChEMBL | Assay Description Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cells | Bioorg Med Chem Lett 10: 1807-10 (2000) BindingDB Entry DOI: 10.7270/Q2765FVB | |||||||||||
More data for this Ligand-Target Pair |
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