Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50178136 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Antagonist activity at recombinant GluK3 receptor (unknown origin) expressed in Xenopus oocyte assessed as inhibition of glutamate-induced current am... | Bioorg Med Chem Lett 26: 5568-5572 (2016) Article DOI: 10.1016/j.bmcl.2016.09.075 BindingDB Entry DOI: 10.7270/Q29S1T0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50207594 (2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cells | J Med Chem 48: 7867-81 (2005) Article DOI: 10.1021/jm050584l BindingDB Entry DOI: 10.7270/Q2V69KCT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50364074 (CHEMBL1950805) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Antagonist activity at human recombinant GluK3 receptor expressed in human HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx... | J Med Chem 55: 327-41 (2012) Article DOI: 10.1021/jm201230z BindingDB Entry DOI: 10.7270/Q2TD9XTJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50185318 ((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.64E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Displacement of [3H]kainate from human GLUK7 expressed in HEK293 cell membranes | J Med Chem 49: 2579-92 (2006) Article DOI: 10.1021/jm051086f BindingDB Entry DOI: 10.7270/Q2FQ9W76 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Homo sapiens (Human)) | BDBM50178148 ((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Walk Curated by ChEMBL | Assay Description Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cells | J Med Chem 48: 7867-81 (2005) Article DOI: 10.1021/jm050584l BindingDB Entry DOI: 10.7270/Q2V69KCT | |||||||||||
More data for this Ligand-Target Pair |