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Compile Data Set for Download or QSAR

Found 211 hits of ki for UniProtKB: P39086   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM85740
PNG
(Dysiherbaine)
Show SMILES CN[C@H]1[C@H]2O[C@](C[C@H](N)C(O)=O)(C[C@H]2OC[C@H]1O)C(O)=O
Show InChI InChI=1S/C12H20N2O7/c1-14-8-6(15)4-20-7-3-12(11(18)19,21-9(7)8)2-5(13)10(16)17/h5-9,14-15H,2-4,13H2,1H3,(H,16,17)(H,18,19)/t5-,6+,7+,8+,9-,12+/m0/s1
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 0.740n/an/an/an/an/an/an/an/a



Yokohama City University

Curated by ChEMBL


Assay Description
Displacement of [3H]kianic acid from recombinant GluK1 kainate receptor (unknown origin) expressed in HEK293 cell membranes measured after 1 hr

Bioorg Med Chem Lett 26: 5164-5167 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.074
BindingDB Entry DOI: 10.7270/Q2ZG6V6F
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50031704
PNG
((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...)
Show SMILES C[C@H](C[C@H](N)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,4+/m1/s1
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 3n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50116042
PNG
(CHEMBL63861 | {7-[3-(4-Benzyl-piperazin-1-ylmethyl...)
Show SMILES OC(=O)Cn1c2cc(c(cc2[nH]c(=O)c1=O)[N+]([O-])=O)-n1ccc(CN2CCN(Cc3ccccc3)CC2)c1
Show InChI InChI=1S/C26H26N6O6/c33-24(34)17-31-21-13-22(23(32(37)38)12-20(21)27-25(35)26(31)36)30-7-6-19(16-30)15-29-10-8-28(9-11-29)14-18-4-2-1-3-5-18/h1-7,12-13,16H,8-11,14-15,17H2,(H,27,35)(H,33,34)
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 3.80n/an/an/an/an/an/an/an/a



Abbott GmbH & Co. KG

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand

Bioorg Med Chem Lett 12: 2113-6 (2002)


BindingDB Entry DOI: 10.7270/Q22806XK
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088223
PNG
(CHEMBL61751 | E-2-Amino-4-(3-naphthalen-1-yl-allyl...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1cccc2ccccc12)C(O)=O)C(O)=O
Show InChI InChI=1S/C18H19NO4/c19-16(18(22)23)11-14(17(20)21)9-4-8-13-7-3-6-12-5-1-2-10-15(12)13/h1-8,10,14,16H,9,11,19H2,(H,20,21)(H,22,23)/b8-4+/t14-,16+/m1/s1
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 7n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088197
PNG
(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16ClNO4/c15-11-6-4-9(5-7-11)2-1-3-10(13(17)18)8-12(16)14(19)20/h1-2,4-7,10,12H,3,8,16H2,(H,17,18)(H,19,20)/b2-1+/t10-,12+/m1/s1
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 8n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088197
PNG
(CHEMBL58590 | E-2-Amino-4-[3-(4-chloro-phenyl)-all...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16ClNO4/c15-11-6-4-9(5-7-11)2-1-3-10(13(17)18)8-12(16)14(19)20/h1-2,4-7,10,12H,3,8,16H2,(H,17,18)(H,19,20)/b2-1+/t10-,12+/m1/s1
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 8n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM85741
PNG
(ATPA | CAS_140158-50-5 | NSC_2253)
Show SMILES CC(C)(C)c1o[nH]c(=O)c1CC(N)C(O)=O
Show InChI InChI=1S/C10H16N2O4/c1-10(2,3)7-5(8(13)12-16-7)4-6(11)9(14)15/h6H,4,11H2,1-3H3,(H,12,13)(H,14,15)
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 9.40n/an/an/an/an/an/an/an/a



NeuroSearch A/S

Curated by PDSP Ki Database




J Pharmacol Exp Ther 309: 1003-10 (2004)


Article DOI: 10.1124/jpet.103.062794
BindingDB Entry DOI: 10.7270/Q2610XX3
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088229
PNG
(2-Amino-4-prop-2-ynyl-pentanedioic acid | CHEMBL59...)
Show SMILES N[C@@H](C[C@@H](CC#C)C(O)=O)C(O)=O
Show InChI InChI=1S/C8H11NO4/c1-2-3-5(7(10)11)4-6(9)8(12)13/h1,5-6H,3-4,9H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1
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 11.6n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50116048
PNG
(CHEMBL67828 | {6-Nitro-2,3-dioxo-7-[3-(4-phenethyl...)
Show SMILES OC(=O)Cn1c2cc(c(cc2[nH]c(=O)c1=O)[N+]([O-])=O)-n1ccc(CN2CCN(CCc3ccccc3)CC2)c1
Show InChI InChI=1S/C27H28N6O6/c34-25(35)18-32-22-15-23(24(33(38)39)14-21(22)28-26(36)27(32)37)31-9-7-20(17-31)16-30-12-10-29(11-13-30)8-6-19-4-2-1-3-5-19/h1-5,7,9,14-15,17H,6,8,10-13,16,18H2,(H,28,36)(H,34,35)
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 12n/an/an/an/an/an/an/an/a



Abbott GmbH & Co. KG

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand

Bioorg Med Chem Lett 12: 2113-6 (2002)


BindingDB Entry DOI: 10.7270/Q22806XK
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088222
PNG
((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc2ccccc2c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C18H19NO4/c19-16(18(22)23)11-15(17(20)21)7-3-4-12-8-9-13-5-1-2-6-14(13)10-12/h1-6,8-10,15-16H,7,11,19H2,(H,20,21)(H,22,23)/b4-3+/t15-,16+/m1/s1
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 14n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088222
PNG
((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc2ccccc2c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C18H19NO4/c19-16(18(22)23)11-15(17(20)21)7-3-4-12-8-9-13-5-1-2-6-14(13)10-12/h1-6,8-10,15-16H,7,11,19H2,(H,20,21)(H,22,23)/b4-3+/t15-,16+/m1/s1
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 15n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity against Ionotropic glutamate receptor ionotropic kainate 1 in HK293 cells using [3H]-kainate as radioligand;...

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088222
PNG
((2S,4R)-2-Amino-4-((E)-3-naphthalen-2-yl-allyl)-pe...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc2ccccc2c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C18H19NO4/c19-16(18(22)23)11-15(17(20)21)7-3-4-12-8-9-13-5-1-2-6-14(13)10-12/h1-6,8-10,15-16H,7,11,19H2,(H,20,21)(H,22,23)/b4-3+/t15-,16+/m1/s1
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 15n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50494356
PNG
(CHEMBL3088070)
Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C23H24ClN5O3.ClH/c24-17-5-1-13(2-6-17)14-4-8-19(22-26-28-29-27-22)21(11-14)32-18-7-3-15-12-25-20(23(30)31)10-16(15)9-18;/h1-2,4-6,8,11,15-16,18,20,25H,3,7,9-10,12H2,(H,30,31)(H,26,27,28,29);1H/t15-,16+,18-,20-;/m0./s1
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 20n/an/an/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Displacement of [3H]ATPA from human Gluk1 receptor

Bioorg Med Chem Lett 23: 6463-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.045
BindingDB Entry DOI: 10.7270/Q2XS5ZBW
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088212
PNG
(2-Amino-4-but-2-enyl-pentanedioic acid(LY339180) |...)
Show SMILES C\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H15NO4/c1-2-3-4-6(8(11)12)5-7(10)9(13)14/h2-3,6-7H,4-5,10H2,1H3,(H,11,12)(H,13,14)/b3-2+/t6-,7+/m1/s1
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 21n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM141501
PNG
(US8921370, 2 | US9656975, 2)
Show SMILES Cc1cccc(n1)C(=O)NC12CCC(C1)(CCC2)NC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C22H24ClN3O2/c1-15-5-2-8-18(24-15)20(28)26-22-10-4-9-21(14-22,11-12-22)25-19(27)16-6-3-7-17(23)13-16/h2-3,5-8,13H,4,9-12,14H2,1H3,(H,25,27)(H,26,28)
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US Patent
 27n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...

US Patent US9656975 (2017)


BindingDB Entry DOI: 10.7270/Q29G5PVM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088228
PNG
(2-Amino-4-but-2-ynyl-pentanedioic acid | CHEMBL620...)
Show SMILES CC#CC[C@H](C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c1-2-3-4-6(8(11)12)5-7(10)9(13)14/h6-7H,4-5,10H2,1H3,(H,11,12)(H,13,14)/t6-,7+/m1/s1
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 28.9n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088203
PNG
(CHEMBL301915 | E-2-Amino-4-[3-(4-bromo-phenyl)-all...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(Br)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16BrNO4/c15-11-6-4-9(5-7-11)2-1-3-10(13(17)18)8-12(16)14(19)20/h1-2,4-7,10,12H,3,8,16H2,(H,17,18)(H,19,20)/b2-1+/t10-,12+/m1/s1
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 30n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088216
PNG
(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Show SMILES COc1ccccc1\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H19NO5/c1-21-13-8-3-2-5-10(13)6-4-7-11(14(17)18)9-12(16)15(19)20/h2-6,8,11-12H,7,9,16H2,1H3,(H,17,18)(H,19,20)/b6-4+/t11-,12+/m1/s1
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 30n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088216
PNG
(CHEMBL59284 | E-2-Amino-4-[3-(2-methoxy-phenyl)-al...)
Show SMILES COc1ccccc1\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H19NO5/c1-21-13-8-3-2-5-10(13)6-4-7-11(14(17)18)9-12(16)15(19)20/h2-6,8,11-12H,7,9,16H2,1H3,(H,17,18)(H,19,20)/b6-4+/t11-,12+/m1/s1
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 30n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088235
PNG
(CHEMBL300368 | E-2-Amino-4-[3-(4-methylsulfanyl-ph...)
Show SMILES CSc1ccc(\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O)cc1
Show InChI InChI=1S/C15H19NO4S/c1-21-12-7-5-10(6-8-12)3-2-4-11(14(17)18)9-13(16)15(19)20/h2-3,5-8,11,13H,4,9,16H2,1H3,(H,17,18)(H,19,20)/b3-2+/t11-,13+/m1/s1
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 32n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091477
PNG
((S)-2-Amino-4-cyclopentylidene-pentanedioic acid |...)
Show SMILES [#7]-[#6@@H](-[#6]\[#6](-[#6](-[#8])=O)=[#6]-1\[#6]-[#6]-[#6]-[#6]-1)-[#6](-[#8])=O
Show InChI InChI=1S/C10H15NO4/c11-8(10(14)15)5-7(9(12)13)6-3-1-2-4-6/h8H,1-5,11H2,(H,12,13)(H,14,15)/t8-/m0/s1
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 33n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM141506
PNG
(US8921370, 160 | US9656975, 160)
Show SMILES Cc1cncc(n1)C(=O)N[C@]12CC[C@](C1)(CCC2)NC(=O)c1cccc(F)c1 |r|
Show InChI InChI=1S/C21H23FN4O2/c1-14-11-23-12-17(24-14)19(28)26-21-7-3-6-20(13-21,8-9-21)25-18(27)15-4-2-5-16(22)10-15/h2,4-5,10-12H,3,6-9,13H2,1H3,(H,25,27)(H,26,28)/t20-,21+/m0/s1
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 35n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...

US Patent US9656975 (2017)


BindingDB Entry DOI: 10.7270/Q29G5PVM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM141505
PNG
(US8921370, 126 | US9656975, 126)
Show SMILES Cc1cccc(n1)C(=O)N[C@@]12CC[C@@](C1)(CCC2)NC(=O)c1ccccn1 |r|
Show InChI InChI=1S/C21H24N4O2/c1-15-6-4-8-17(23-15)19(27)25-21-10-5-9-20(14-21,11-12-21)24-18(26)16-7-2-3-13-22-16/h2-4,6-8,13H,5,9-12,14H2,1H3,(H,24,26)(H,25,27)/t20-,21+/m1/s1
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 39n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...

US Patent US9656975 (2017)


BindingDB Entry DOI: 10.7270/Q29G5PVM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088224
PNG
(CHEMBL305346 | E-2-Amino-4-[3-(3-methoxy-phenyl)-a...)
Show SMILES COc1cccc(\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O)c1
Show InChI InChI=1S/C15H19NO5/c1-21-12-7-3-5-10(8-12)4-2-6-11(14(17)18)9-13(16)15(19)20/h2-5,7-8,11,13H,6,9,16H2,1H3,(H,17,18)(H,19,20)/b4-2+/t11-,13+/m1/s1
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 40n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088196
PNG
(2-Amino-4-(3-chloro-allyl)-pentanedioic acid | CHE...)
Show SMILES N[C@@H](C[C@@H](C\C=C\Cl)C(O)=O)C(O)=O
Show InChI InChI=1S/C8H12ClNO4/c9-3-1-2-5(7(11)12)4-6(10)8(13)14/h1,3,5-6H,2,4,10H2,(H,11,12)(H,13,14)/b3-1+/t5-,6+/m1/s1
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 41n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088217
PNG
(CHEMBL58095 | E-2-Amino-4-(3-phenyl-allyl)-pentane...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H17NO4/c15-12(14(18)19)9-11(13(16)17)8-4-7-10-5-2-1-3-6-10/h1-7,11-12H,8-9,15H2,(H,16,17)(H,18,19)/b7-4+/t11-,12+/m1/s1
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 44n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088221
PNG
(CHEMBL293118 | E-2-Amino-4-[3-(3,4-dichloro-phenyl...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(Cl)c(Cl)c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H15Cl2NO4/c15-10-5-4-8(6-11(10)16)2-1-3-9(13(18)19)7-12(17)14(20)21/h1-2,4-6,9,12H,3,7,17H2,(H,18,19)(H,20,21)/b2-1+/t9-,12+/m1/s1
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 49n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50200526
PNG
(CHEMBL1234118)
Show SMILES OC(=O)[C@@H]1CC(F)(F)CN1C[C@H]1CC[C@H]2CN[C@@H](C[C@H]2C1)C(O)=O |r|
Show InChI InChI=1S/C16H24F2N2O4/c17-16(18)5-13(15(23)24)20(8-16)7-9-1-2-10-6-19-12(14(21)22)4-11(10)3-9/h9-13,19H,1-8H2,(H,21,22)(H,23,24)/t9-,10-,11+,12-,13-/m0/s1
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 50n/an/an/an/an/an/an/an/a



McGill University

Curated by ChEMBL


Assay Description
Displacement of [3H]kainate from human GluK1 expressed in HEK293 cell membranes after 60 mins by scintillation counting method

J Med Chem 60: 441-457 (2017)


Article DOI: 10.1021/acs.jmedchem.6b01516
BindingDB Entry DOI: 10.7270/Q2G44SJJ
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088200
PNG
(CHEMBL291491 | E-2-Amino-4-[3-(4-trifluoromethyl-p...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(cc1)C(F)(F)F)C(O)=O)C(O)=O
Show InChI InChI=1S/C15H16F3NO4/c16-15(17,18)11-6-4-9(5-7-11)2-1-3-10(13(20)21)8-12(19)14(22)23/h1-2,4-7,10,12H,3,8,19H2,(H,20,21)(H,22,23)/b2-1+/t10-,12+/m1/s1
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 52n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091474
PNG
((2S,4E)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Show SMILES CC(C)\C=C(/C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H15NO4/c1-5(2)3-6(8(11)12)4-7(10)9(13)14/h3,5,7H,4,10H2,1-2H3,(H,11,12)(H,13,14)/b6-3+/t7-/m0/s1
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 54n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088213
PNG
((2S,4R)-4-allyl glutamate | 2-Allyl-4-amino-pentan...)
Show SMILES N[C@@H](C[C@@H](CC=C)C(O)=O)C(O)=O
Show InChI InChI=1S/C8H13NO4/c1-2-3-5(7(10)11)4-6(9)8(12)13/h2,5-6H,1,3-4,9H2,(H,10,11)(H,12,13)/t5-,6+/m1/s1
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 56n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088199
PNG
(CHEMBL302680 | E-2-Amino-4-[3-(4-isopropyl-phenyl)...)
Show SMILES CC(C)c1ccc(\C=C\C[C@H](C[C@H](N)C(O)=O)C(O)=O)cc1
Show InChI InChI=1S/C17H23NO4/c1-11(2)13-8-6-12(7-9-13)4-3-5-14(16(19)20)10-15(18)17(21)22/h3-4,6-9,11,14-15H,5,10,18H2,1-2H3,(H,19,20)(H,21,22)/b4-3+/t14-,15+/m1/s1
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 58n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088234
PNG
(CHEMBL60168 | E-2-Amino-4-[3-(4-nitro-phenyl)-ally...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(cc1)[N+]([O-])=O)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16N2O6/c15-12(14(19)20)8-10(13(17)18)3-1-2-9-4-6-11(7-5-9)16(21)22/h1-2,4-7,10,12H,3,8,15H2,(H,17,18)(H,19,20)/b2-1+/t10-,12+/m1/s1
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 59n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088227
PNG
(CHEMBL58054 | E-2-Amino-4-[3-(3-chloro-phenyl)-all...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1cccc(Cl)c1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16ClNO4/c15-11-6-2-4-9(7-11)3-1-5-10(13(17)18)8-12(16)14(19)20/h1-4,6-7,10,12H,5,8,16H2,(H,17,18)(H,19,20)/b3-1+/t10-,12+/m1/s1
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 60n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091481
PNG
((S)-2-Amino-4-propylidene-pentanedioicacid | CHEMB...)
Show SMILES CC\C=C(\C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C8H13NO4/c1-2-3-5(7(10)11)4-6(9)8(12)13/h3,6H,2,4,9H2,1H3,(H,10,11)(H,12,13)/b5-3-/t6-/m0/s1
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 61n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM141508
PNG
(US8921370, 171 | US9656975, 171)
Show SMILES Cc1csc(n1)C(=O)NC12CCC(C1)(CCC2)C(=O)Nc1cccc(C)n1
Show InChI InChI=1S/C20H24N4O2S/c1-13-5-3-6-15(21-13)23-18(26)19-7-4-8-20(12-19,10-9-19)24-16(25)17-22-14(2)11-27-17/h3,5-6,11H,4,7-10,12H2,1-2H3,(H,24,25)(H,21,23,26)
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 65n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...

US Patent US9656975 (2017)


BindingDB Entry DOI: 10.7270/Q29G5PVM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088205
PNG
(CHEMBL294683 | E-2-Amino-4-[3-(4-fluoro-phenyl)-al...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(F)cc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H16FNO4/c15-11-6-4-9(5-7-11)2-1-3-10(13(17)18)8-12(16)14(19)20/h1-2,4-7,10,12H,3,8,16H2,(H,17,18)(H,19,20)/b2-1+/t10-,12+/m1/s1
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 78n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM141502
PNG
(US8921370, 6 | US9656975, 6)
Show SMILES Cc1cncc(n1)C(=O)NC12CCC(C1)(CCC2)NC(=O)c1cccc(F)c1
Show InChI InChI=1S/C21H23FN4O2/c1-14-11-23-12-17(24-14)19(28)26-21-7-3-6-20(13-21,8-9-21)25-18(27)15-4-2-5-16(22)10-15/h2,4-5,10-12H,3,6-9,13H2,1H3,(H,25,27)(H,26,28)
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 78n/an/an/an/an/an/an/an/a



H. Lundbeck A/S

US Patent


Assay Description
Binding assays were performed as described in [J. A. O'Brien et al. Mol Pharmacol., 2003, 64, 731-740] with slight modifications, including that ...

US Patent US9656975 (2017)


BindingDB Entry DOI: 10.7270/Q29G5PVM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091485
PNG
((S)-2-Amino-4-butylidene-pentanedioic acid | CHEMB...)
Show SMILES CCC\C=C(\C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H15NO4/c1-2-3-4-6(8(11)12)5-7(10)9(13)14/h4,7H,2-3,5,10H2,1H3,(H,11,12)(H,13,14)/b6-4-/t7-/m0/s1
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 80n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50166288
PNG
((S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5...)
Show SMILES Cn1nnc(n1)-c1o[nH]c(=O)c1C[C@H](N)C(O)=O
Show InChI InChI=1S/C8H10N6O4/c1-14-11-6(10-13-14)5-3(7(15)12-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,12,15)(H,16,17)/t4-/m0/s1
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 81n/an/an/an/an/an/an/an/a



The Danish University of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Binding affinity for kainate Glutamate receptor GluR5 expressed in Sf9 cells

J Med Chem 48: 3438-42 (2005)


Article DOI: 10.1021/jm050014l
BindingDB Entry DOI: 10.7270/Q2H70FBJ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091479
PNG
((S)-2-Amino-4-(2,2-dimethyl-propylidene)-pentanedi...)
Show SMILES CC(C)(C)\C=C(/C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C10H17NO4/c1-10(2,3)5-6(8(12)13)4-7(11)9(14)15/h5,7H,4,11H2,1-3H3,(H,12,13)(H,14,15)/b6-5+/t7-/m0/s1
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 86n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50494342
PNG
(CHEMBL3088072)
Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1cccs1 |r|
Show InChI InChI=1S/C21H23N5O3S.ClH/c27-21(28)17-9-14-8-15(5-3-13(14)11-22-17)29-18-10-12(19-2-1-7-30-19)4-6-16(18)20-23-25-26-24-20;/h1-2,4,6-7,10,13-15,17,22H,3,5,8-9,11H2,(H,27,28)(H,23,24,25,26);1H/t13-,14+,15-,17-;/m0./s1
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 90n/an/an/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Displacement of [3H]ATPA from human Gluk1 receptor

Bioorg Med Chem Lett 23: 6463-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.045
BindingDB Entry DOI: 10.7270/Q2XS5ZBW
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091475
PNG
((2S,4Z)-2-amino-4-(2-methylpropylidene)pentanedioi...)
Show SMILES CC(C)\C=C(\C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C9H15NO4/c1-5(2)3-6(8(11)12)4-7(10)9(13)14/h3,5,7H,4,10H2,1-2H3,(H,11,12)(H,13,14)/b6-3-/t7-/m0/s1
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 94n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50116040
PNG
((7-{3-[3-(4-Nitro-phenyl)-ureidomethyl]-pyrrol-1-y...)
Show SMILES OC(=O)Cn1c2cc(c(cc2[nH]c(=O)c1=O)C(F)(F)F)-n1ccc(CNC(=O)Nc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C23H17F3N6O7/c24-23(25,26)15-7-16-18(31(11-19(33)34)21(36)20(35)29-16)8-17(15)30-6-5-12(10-30)9-27-22(37)28-13-1-3-14(4-2-13)32(38)39/h1-8,10H,9,11H2,(H,29,35)(H,33,34)(H2,27,28,37)
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 100n/an/an/an/an/an/an/an/a



Abbott GmbH & Co. KG

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human GluR5 subunit stably expressed in cultured HEK-293 cells using [3]H-kainate as radioligand

Bioorg Med Chem Lett 12: 2113-6 (2002)


BindingDB Entry DOI: 10.7270/Q22806XK
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50494350
PNG
(CHEMBL3088064)
Show SMILES Cl.[H][C@@]12CC[C@@H](C[C@]1([H])C[C@H](NC2)C(O)=O)Oc1cc(ccc1-c1nnn[nH]1)-c1ccccc1 |r|
Show InChI InChI=1S/C23H25N5O3.ClH/c29-23(30)20-11-17-10-18(8-6-16(17)13-24-20)31-21-12-15(14-4-2-1-3-5-14)7-9-19(21)22-25-27-28-26-22;/h1-5,7,9,12,16-18,20,24H,6,8,10-11,13H2,(H,29,30)(H,25,26,27,28);1H/t16-,17+,18-,20-;/m0./s1
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 100n/an/an/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Displacement of [3H]ATPA from human Gluk1 receptor

Bioorg Med Chem Lett 23: 6463-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.045
BindingDB Entry DOI: 10.7270/Q2XS5ZBW
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088230
PNG
((2S,4R)-4-propylglutamic acid | 2-Amino-4-propyl-p...)
Show SMILES CCC[C@H](C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C8H15NO4/c1-2-3-5(7(10)11)4-6(9)8(12)13/h5-6H,2-4,9H2,1H3,(H,10,11)(H,12,13)/t5-,6+/m1/s1
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 123n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088198
PNG
(CHEMBL59297 | E-2-Amino-4-[3-(2,6-dichloro-phenyl)...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1c(Cl)cccc1Cl)C(O)=O)C(O)=O
Show InChI InChI=1S/C14H15Cl2NO4/c15-10-5-2-6-11(16)9(10)4-1-3-8(13(18)19)7-12(17)14(20)21/h1-2,4-6,8,12H,3,7,17H2,(H,18,19)(H,20,21)/b4-1+/t8-,12+/m1/s1
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 131n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50088232
PNG
(CHEMBL292896 | E-2-Amino-4-(3-biphenyl-4-yl-allyl)...)
Show SMILES N[C@@H](C[C@@H](C\C=C\c1ccc(cc1)-c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C20H21NO4/c21-18(20(24)25)13-17(19(22)23)8-4-5-14-9-11-16(12-10-14)15-6-2-1-3-7-15/h1-7,9-12,17-18H,8,13,21H2,(H,22,23)(H,24,25)/b5-4+/t17-,18+/m1/s1
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 133n/an/an/an/an/an/an/an/a



Lilly, S.A.

Curated by ChEMBL


Assay Description
Binding affinity against human ionotropic glutamate receptor kainate 1 in HK293 cells using [3H]-kainate as radioligand

J Med Chem 43: 1958-68 (2000)


BindingDB Entry DOI: 10.7270/Q2FX78QB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091478
PNG
((S)-2-Amino-4-pentylidene-pentanedioicacid | CHEMB...)
Show SMILES CCCC\C=C(\C[C@H](N)C(O)=O)C(O)=O
Show InChI InChI=1S/C10H17NO4/c1-2-3-4-5-7(9(12)13)6-8(11)10(14)15/h5,8H,2-4,6,11H2,1H3,(H,12,13)(H,14,15)/b7-5-/t8-/m0/s1
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 150n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1


(Homo sapiens (Human))		BDBM50091488
PNG
((S)-2-Amino-4-[1-cyclopentyl-meth-(E)-ylidene]-pen...)
Show SMILES N[C@@H](C\C(=C/C1CCCC1)C(O)=O)C(O)=O
Show InChI InChI=1S/C11H17NO4/c12-9(11(15)16)6-8(10(13)14)5-7-3-1-2-4-7/h5,7,9H,1-4,6,12H2,(H,13,14)(H,15,16)/b8-5+/t9-/m0/s1
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 152n/an/an/an/an/an/an/an/a



Eli Lilly and Company Ltd

Curated by ChEMBL


Assay Description
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cell...

Bioorg Med Chem Lett 10: 1807-10 (2000)


BindingDB Entry DOI: 10.7270/Q2765FVB
More data for this
Ligand-Target Pair
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