Compile Data Set for Download or QSAR

Found 505 hits of ec50 for UniProtKB: P35439   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583031 (CHEMBL5081078) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583020 (CHEMBL5087374) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1C(F)(F)F)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50432711 (CHEMBL2348224) Show SMILES C[C@@]1(C[C@H]1[C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C7H11NO4/c1-7(6(11)12)2-3(7)4(8)5(9)10/h3-4H,2,8H2,1H3,(H,9,10)(H,11,12)/t3-,4-,7-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	45	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50583031 (CHEMBL5081078) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583019 (CHEMBL5081008) Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583032 (CHEMBL5090386) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1[N+]([O-])=O)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	74	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583031 (CHEMBL5081078) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50220152 ((1S,2R)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	83	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM18133 (2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...) Show SMILES NCC(O)=O Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50583019 (CHEMBL5081008) Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	93	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583021 (CHEMBL5091289) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50220152 ((1S,2R)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2C receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583023 (CHEMBL5081203) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50432711 (CHEMBL2348224) Show SMILES C[C@@]1(C[C@H]1[C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C7H11NO4/c1-7(6(11)12)2-3(7)4(8)5(9)10/h3-4H,2,8H2,1H3,(H,9,10)(H,11,12)/t3-,4-,7-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	124	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2C receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50583020 (CHEMBL5087374) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1C(F)(F)F)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50583022 (CHEMBL5085583) Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM23167 ((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...) Show SMILES N[C@H](CO)C(O)=O Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583019 (CHEMBL5081008) Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50583021 (CHEMBL5091289) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM23167 ((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...) Show SMILES N[C@H](CO)C(O)=O Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM18133 (2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...) Show SMILES NCC(O)=O Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50583022 (CHEMBL5085583) Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583021 (CHEMBL5091289) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM18133 (2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...) Show SMILES NCC(O)=O Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50583023 (CHEMBL5081203) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583022 (CHEMBL5085583) Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50220152 ((1S,2R)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...) Show SMILES N[C@@H]([C@@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO4/c7-4(6(10)11)2-1-3(2)5(8)9/h2-4H,1,7H2,(H,8,9)(H,10,11)/t2-,3+,4+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	262	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2A receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50238357 (CHEMBL4100452) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C30H32F3NO3S/c1-19(2)36-25-10-8-24(9-11-25)35-18-28-27-13-12-26(37-20(3)4)17-21(27)14-15-34(28)29(38)22-6-5-7-23(16-22)30(31,32)33/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50583023 (CHEMBL5081203) Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01810 BindingDB Entry DOI: 10.7270/Q21R6VFZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50432710 (CHEMBL2348221) Show SMILES CC[C@@]1(C[C@H]1[C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C8H13NO4/c1-2-8(7(12)13)3-4(8)5(9)6(10)11/h4-5H,2-3,9H2,1H3,(H,10,11)(H,12,13)/t4-,5-,8-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	272	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50432711 (CHEMBL2348224) Show SMILES C[C@@]1(C[C@H]1[C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C7H11NO4/c1-7(6(11)12)2-3(7)4(8)5(9)10/h3-4H,2,8H2,1H3,(H,9,10)(H,11,12)/t3-,4-,7-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	277	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Agonist activity at rat recombinant wild type GluN1/GluN2A receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp technique				J Med Chem 56: 4071-81 (2013) Article DOI: 10.1021/jm400346a BindingDB Entry DOI: 10.7270/Q20G3MHR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238352 (CHEMBL4061206) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C28H30BrNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436093 (CHEMBL2397268) Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C31H28BrNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078513 (7,8-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) Show SMILES OC(=O)c1nc2n(n1)c1cc(Cl)c(Cl)cc1[nH]c2=O Show InChI InChI=1S/C10H4Cl2N4O3/c11-3-1-5-6(2-4(3)12)16-8(9(17)13-5)14-7(15-16)10(18)19/h1-2H,(H,13,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the NMDA receptor-ion channel complex was demonstrated by the ability to inhibit the binding of thechannel-blocking agent [3...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50436093 (CHEMBL2397268) Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C31H28BrNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50238364 (CHEMBL4064008) Show SMILES COc1ccc(OC[C@H]2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 |r| Show InChI InChI=1S/C27H28ClNO3S/c1-18(2)32-24-11-12-25-19(16-24)13-14-29(27(33)20-5-4-6-21(28)15-20)26(25)17-31-23-9-7-22(30-3)8-10-23/h4-12,15-16,18,26H,13-14,17H2,1-3H3/t26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001266 (5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...) Show SMILES OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1 Show InChI InChI=1S/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238357 (CHEMBL4100452) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C30H32F3NO3S/c1-19(2)36-25-10-8-24(9-11-25)35-18-28-27-13-12-26(37-20(3)4)17-21(27)14-15-34(28)29(38)22-6-5-7-23(16-22)30(31,32)33/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50238352 (CHEMBL4061206) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Br)c2)cc1 Show InChI InChI=1S/C28H30BrNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50238357 (CHEMBL4100452) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C30H32F3NO3S/c1-19(2)36-25-10-8-24(9-11-25)35-18-28-27-13-12-26(37-20(3)4)17-21(27)14-15-34(28)29(38)22-6-5-7-23(16-22)30(31,32)33/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50238363 (CHEMBL4099510) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(c2)C(F)(F)F)cc1 Show InChI InChI=1S/C29H30F3NO3S/c1-4-34-23-8-10-24(11-9-23)35-18-27-26-13-12-25(36-19(2)3)17-20(26)14-15-33(27)28(37)21-6-5-7-22(16-21)29(30,31)32/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50238354 (CHEMBL4070902) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2ccc(F)c(Cl)c2)cc1 Show InChI InChI=1S/C28H29ClFNO3S/c1-4-32-21-6-8-22(9-7-21)33-17-27-24-11-10-23(34-18(2)3)15-19(24)13-14-31(27)28(35)20-5-12-26(30)25(29)16-20/h5-12,15-16,18,27H,4,13-14,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50238335 (CHEMBL4083076) Show SMILES CCOc1ccc(OC[C@H]2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(F)c2)cc1 |r| Show InChI InChI=1S/C28H30FNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2C receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50545700 (CHEMBL4633060) Show SMILES COc1ccc(OCC2N(Cc3cccc(c3)C(F)(F)F)C(=O)Cc3cc(OC(C)C)ccc23)cc1 Show InChI InChI=1S/C28H28F3NO4/c1-18(2)36-24-11-12-25-20(14-24)15-27(33)32(16-19-5-4-6-21(13-19)28(29,30)31)26(25)17-35-23-9-7-22(34-3)8-10-23/h4-14,18,26H,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50545699 (CHEMBL4636021) Show SMILES COc1ccc(OCC2N(Cc3cccc(Cl)c3)C(=O)Cc3cc(OCC(C)C)ccc23)cc1 Show InChI InChI=1S/C28H30ClNO4/c1-19(2)17-33-25-11-12-26-21(14-25)15-28(31)30(16-20-5-4-6-22(29)13-20)27(26)18-34-24-9-7-23(32-3)8-10-24/h4-14,19,27H,15-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50545698 (CHEMBL4637429) Show SMILES COc1ccc(OCC2N(Cc3cccc(Cl)c3)C(=O)Cc3cc(OC(C)C)ccc23)cc1 Show InChI InChI=1S/C27H28ClNO4/c1-18(2)33-24-11-12-25-20(14-24)15-27(30)29(16-19-5-4-6-21(28)13-19)26(25)17-32-23-9-7-22(31-3)8-10-23/h4-14,18,26H,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutam...				J Med Chem 63: 7569-7600 (2020) Article DOI: 10.1021/acs.jmedchem.9b01733 BindingDB Entry DOI: 10.7270/Q26D5XJV
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50436094 (CHEMBL2397267) Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C31H28ClNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2D receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50238367 (CHEMBL4089357) Show SMILES CCOc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C28H30ClNO3S/c1-4-31-23-8-10-24(11-9-23)32-18-27-26-13-12-25(33-19(2)3)17-20(26)14-15-30(27)28(34)21-6-5-7-22(29)16-21/h5-13,16-17,19,27H,4,14-15,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat))	BDBM50436094 (CHEMBL2397267) Show SMILES COc1ccc(OCC2N(CCc3cc(OCc4ccccc4)ccc23)C(=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C31H28ClNO4/c1-35-26-10-12-27(13-11-26)37-21-30-29-15-14-28(36-20-22-6-3-2-4-7-22)19-23(29)16-17-33(30)31(34)24-8-5-9-25(32)18-24/h2-15,18-19,30H,16-17,20-21H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Activity at rat recombinant GluN1/GluN2C receptor assessed as potentiation of glycine/glutamate-induced activation by two-electrode voltage clamp tec...				J Med Chem 56: 5351-81 (2014) Article DOI: 10.1021/jm400177t BindingDB Entry DOI: 10.7270/Q26W9CH4
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat))	BDBM50238355 (CHEMBL4091770) Show SMILES CC(C)Oc1ccc(OCC2N(CCc3cc(OC(C)C)ccc23)C(=S)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C29H32ClNO3S/c1-19(2)33-25-10-8-24(9-11-25)32-18-28-27-13-12-26(34-20(3)4)17-21(27)14-15-31(28)29(35)22-6-5-7-23(30)16-22/h5-13,16-17,19-20,28H,14-15,18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	410	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Positive allosteric modulation of recombinant rat GluN1/GluN2D receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...				J Med Chem 60: 5556-5585 (2017) Article DOI: 10.1021/acs.jmedchem.7b00239 BindingDB Entry DOI: 10.7270/Q298898H
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 505 total )  |  Next  |  Last  >>

Jump to: