Compile Data Set for Download or QSAR

Found 55 hits of ec50 data for polymerid = 49000630,49000814,49000815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078513 (7,8-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) Show SMILES OC(=O)c1nc2n(n1)c1cc(Cl)c(Cl)cc1[nH]c2=O Show InChI InChI=1S/C10H4Cl2N4O3/c11-3-1-5-6(2-4(3)12)16-8(9(17)13-5)14-7(15-16)10(18)19/h1-2H,(H,13,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the NMDA receptor-ion channel complex was demonstrated by the ability to inhibit the binding of thechannel-blocking agent [3...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50001266 (5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID ...) Show SMILES OC(=O)c1cc(O)c2c(Cl)cc(Cl)cc2n1 Show InChI InChI=1S/C10H5Cl2NO3/c11-4-1-5(12)9-6(2-4)13-7(10(15)16)3-8(9)14/h1-3H,(H,13,14)(H,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078527 (7,9-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) Show SMILES OC(=O)c1nc2n(n1)c1c(Cl)cc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C10H4Cl2N4O3/c11-3-1-4(12)6-5(2-3)13-9(17)8-14-7(10(18)19)15-16(6)8/h1-2H,(H,13,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078507 (7,8-Dichloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5...) Show SMILES CCOC(=O)c1nc2n(n1)c1cc(Cl)c(Cl)cc1[nH]c2=O Show InChI InChI=1S/C12H8Cl2N4O3/c1-2-21-12(20)9-16-10-11(19)15-7-3-5(13)6(14)4-8(7)18(10)17-9/h3-4H,2H2,1H3,(H,15,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | EN3...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 |TLB:7:1:4.5.8:11,10:9:4:2.7.1,0:1:4:8.9.11,THB:7:5:11:2.1.12,12:1:4:8.9.11,12:9:4:2.7.1,6:5:11:2.1.12| Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PDB US Patent	n/a	n/a	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) Show SMILES N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078519 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES OC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C10H5ClN4O3/c11-4-1-2-6-5(3-4)12-9(16)8-13-7(10(17)18)14-15(6)8/h1-3H,(H,12,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078531 (4-Oxo-7-trifluoromethyl-4,5-dihydro-[1,2,4]triazol...) Show SMILES OC(=O)c1nc2n(n1)c1ccc(cc1[nH]c2=O)C(F)(F)F Show InChI InChI=1S/C11H5F3N4O3/c12-11(13,14)4-1-2-6-5(3-4)15-9(19)8-16-7(10(20)21)17-18(6)8/h1-3H,(H,15,19)(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078515 (7-Bromo-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) Show SMILES OC(=O)c1nc2n(n1)c1ccc(Br)cc1[nH]c2=O Show InChI InChI=1S/C10H5BrN4O3/c11-4-1-2-6-5(3-4)12-9(16)8-13-7(10(17)18)14-15(6)8/h1-3H,(H,12,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356624 (US10214478, Compound NM-008) Show SMILES NC12CC3CC(CO[N+]([O-])=O)(C1)CC(CO[N+]([O-])=O)(C3)C2 |TLB:11:1:19:5.4.12,4:5:20:19.3.2,4:3:20:5.11.12,6:5:19:20.1.2,THB:11:5:19:20.1.2| Show InChI InChI=1S/C12H19N3O6/c13-12-3-9-1-10(5-12,7-20-14(16)17)4-11(2-9,6-12)8-21-15(18)19/h9H,1-8,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.37E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078522 (4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...) Show SMILES OC(=O)c1nc2n(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C10H6N4O3/c15-9-8-12-7(10(16)17)13-14(8)6-4-2-1-3-5(6)11-9/h1-4H,(H,11,15)(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356628 (US10214478, Compound NM-009) Show SMILES NC12CC3CC(CCO[N+]([O-])=O)(C1)CC(CCO[N+]([O-])=O)(C3)C2 |TLB:12:1:21:5.4.13,4:5:22:21.3.2,4:3:22:5.12.13,6:5:21:22.1.2,THB:12:5:21:22.1.2| Show InChI InChI=1S/C14H23N3O6/c15-14-7-11-5-12(9-14,1-3-22-16(18)19)8-13(6-11,10-14)2-4-23-17(20)21/h11H,1-10,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356629 (US10214478, Compound NM-011) Show SMILES NC12CC3CC(CCCO[N+]([O-])=O)(C1)CC(CCCO[N+]([O-])=O)(C3)C2 |TLB:13:1:23:5.4.14,4:5:24:23.3.2,4:3:24:5.13.14,6:5:23:24.1.2,THB:13:5:23:24.1.2| Show InChI InChI=1S/C16H27N3O6/c17-16-9-13-7-14(11-16,3-1-5-24-18(20)21)10-15(8-13,12-16)4-2-6-25-19(22)23/h13H,1-12,17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.86E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356623 (US10214478, Compound NM-005) Show SMILES CCC12CC3CC(N)(C1)CC(CCCO[N+]([O-])=O)(C3)C2 |TLB:18:10:8:3.4.5,11:10:3:8.6.5,THB:9:10:3:8.6.5,9:6:3:10.18.19,18:4:8:10.9.19| Show InChI InChI=1S/C15H26N2O3/c1-2-13-6-12-7-14(9-13,4-3-5-20-17(18)19)11-15(16,8-12)10-13/h12H,2-11,16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.06E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078517 (7-Nitro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) Show SMILES OC(=O)c1nc2n(n1)c1ccc(cc1[nH]c2=O)[N+]([O-])=O Show InChI InChI=1S/C10H5N5O5/c16-9-8-12-7(10(17)18)13-14(8)6-2-1-4(15(19)20)3-5(6)11-9/h1-3H,(H,11,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356622 (US10214478, Compound NM-004) Show SMILES CCC12CC3CC(N)(C1)CC(CO[N+]([O-])=O)(C3)C2 |TLB:16:10:8:3.4.5,11:10:3:8.6.5,THB:9:10:3:8.6.5,9:6:3:10.16.17,16:4:8:10.9.17| Show InChI InChI=1S/C13H22N2O3/c1-2-11-3-10-4-12(6-11,9-18-15(16)17)8-13(14,5-10)7-11/h10H,2-9,14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.12E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) Show SMILES CN[C@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356630 (US10214478, Compound NM-012) Show SMILES CC(CO[N+]([O-])=O)CC12CC3CC(N)(C1)CC(CC(C)CO[N+]([O-])=O)(C3)C2 |TLB:25:16:14:9.10.11,17:16:9:14.12.11,THB:15:16:9:14.12.11,15:12:9:16.25.26,25:10:14:16.15.26| Show InChI InChI=1S/C18H31N3O6/c1-13(8-26-20(22)23)3-16-5-15-6-17(10-16,12-18(19,7-15)11-16)4-14(2)9-27-21(24)25/h13-15H,3-12,19H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252360 ((R)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ac...) Show SMILES N[C@@H](C(O)=O)c1ccnn1O |r| Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)/t4-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356621 (US10214478, Compound NM-003) Show SMILES CCC12CC3CC(N)(C1)CC(C3)(C2)O[N+]([O-])=O |TLB:11:10:8:3.4.5,13:10:3:8.6.5,THB:9:10:3:8.6.5,9:6:3:10.11.12,11:4:8:10.9.12| Show InChI InChI=1S/C12H20N2O3/c1-2-10-3-9-4-11(13,6-10)8-12(5-9,7-10)17-14(15)16/h9H,2-8,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) Show SMILES CN[C@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078536 (7-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccc(Cl)cc1[nH]c2=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-20-12(19)9-15-10-11(18)14-7-5-6(13)3-4-8(7)17(10)16-9/h3-5H,2H2,1H3,(H,14,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) Show SMILES CN[C@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356619 (US10214478, Compound NM-001) Show SMILES CC12CC3CC(N)(C1)CC(C3)(C2)O[N+]([O-])=O |TLB:10:9:7:2.3.4,12:9:2:7.5.4,THB:8:9:2:7.5.4,8:5:2:9.10.11,10:3:7:9.8.11| Show InChI InChI=1S/C11H18N2O3/c1-9-2-8-3-10(12,5-9)7-11(4-8,6-9)16-13(14)15/h8H,2-7,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.46E+4	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356620 (US10214478, Compound NM-002) Show SMILES CC12CC3CC(N)(C1)CC(CO[N+]([O-])=O)(C3)C2 |TLB:15:9:7:2.3.4,10:9:2:7.5.4,THB:8:9:2:7.5.4,8:5:2:9.15.16,15:3:7:9.8.16| Show InChI InChI=1S/C12H20N2O3/c1-10-2-9-3-11(5-10,8-17-14(15)16)7-12(13,4-9)6-10/h9H,2-8,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.52E+4	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM356631 (Nitromemantine | US10214478, Compound YQW-036) Show SMILES CCC12CC3(N)CC(CC)(C1)CC(C3)(C2)O[N+]([O-])=O |TLB:8:7:3.4.13:14,6:7:3.4.13:14,6:4:11.7.10:14,5:4:11:10.2.14,THB:3:2:11:4.13.6,3:4:11:10.2.14| Show InChI InChI=1S/C14H24N2O3/c1-3-11-5-12(4-2)7-13(15,6-11)10-14(8-11,9-12)19-16(17)18/h3-10,15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.14E+4	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078510 (8-Chloro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]q...) Show SMILES OC(=O)c1nc2n(n1)c1cc(Cl)ccc1[nH]c2=O Show InChI InChI=1S/C10H5ClN4O3/c11-4-1-2-5-6(3-4)15-8(9(16)12-5)13-7(14-15)10(17)18/h1-3H,(H,12,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.25E+4	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252366 ((R)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-acetic ...) Show SMILES CCc1cnn(O)c1[C@@H](N)C(O)=O |r| Show InChI InChI=1S/C7H11N3O3/c1-2-4-3-9-10(13)6(4)5(8)7(11)12/h3,5,13H,2,8H2,1H3,(H,11,12)/t5-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252363 ((R)-amino-(1-hydroxy-4-methyl-pyrazol-3-yl)-acetic...) Show SMILES Cc1cnn(O)c1[C@@H](N)C(O)=O |r| Show InChI InChI=1S/C6H9N3O3/c1-3-2-8-9(12)5(3)4(7)6(10)11/h2,4,12H,7H2,1H3,(H,10,11)/t4-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) Show SMILES CCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C7H11N3O3/c1-2-4-3-9-10(13)6(4)5(8)7(11)12/h3,5,13H,2,8H2,1H3,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) Show SMILES CCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C7H11N3O3/c1-2-4-3-9-10(13)6(4)5(8)7(11)12/h3,5,13H,2,8H2,1H3,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252434 ((R)-amino-(1-hydroxy-4-chloro-pyrazol-3-yl)-acetic...) Show SMILES N[C@@H](C(O)=O)c1c(Cl)cnn1O |r| Show InChI InChI=1S/C5H6ClN3O3/c6-2-1-8-9(12)4(2)3(7)5(10)11/h1,3,12H,7H2,(H,10,11)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252428 ((R)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acetic...) Show SMILES CCCc1cnn(O)c1[C@@H](N)C(O)=O |r| Show InChI InChI=1S/C8H13N3O3/c1-2-3-5-4-10-11(14)7(5)6(9)8(12)13/h4,6,14H,2-3,9H2,1H3,(H,12,13)/t6-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) Show SMILES CCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C7H11N3O3/c1-2-4-3-9-10(13)6(4)5(8)7(11)12/h3,5,13H,2,8H2,1H3,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078530 (4-Oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]quinoxalin...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccccc1[nH]c2=O Show InChI InChI=1S/C12H10N4O3/c1-2-19-12(18)9-14-10-11(17)13-7-5-3-4-6-8(7)16(10)15-9/h3-6H,2H2,1H3,(H,13,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50013876 (CHEMBL291278 | Methyl aspartic acid | N-Methyl asp...) Show SMILES CN[C@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252359 ((R,S)-2-amino-2-(1-hydroxy-1H-pyrazol-5-yl)acetic ...) Show SMILES NC(C(O)=O)c1ccnn1O Show InChI InChI=1S/C5H7N3O3/c6-4(5(9)10)3-1-2-7-8(3)11/h1-2,4,11H,6H2,(H,9,10)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2A receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252365 ((R,S)-amino-(1-hydroxy-4-ethyl-pyrazol-3-yl)-aceti...) Show SMILES CCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C7H11N3O3/c1-2-4-3-9-10(13)6(4)5(8)7(11)12/h3,5,13H,2,8H2,1H3,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.10E+4	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2C receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078528 (7-Chloro-5-ethyl-4-oxo-4,5-dihydro-[1,2,4]triazolo...) Show SMILES CCn1c2cc(Cl)ccc2n2nc(nc2c1=O)C(O)=O Show InChI InChI=1S/C12H9ClN4O3/c1-2-16-8-5-6(13)3-4-7(8)17-10(11(16)18)14-9(15-17)12(19)20/h3-5H,2H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078511 (8-Nitro-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) Show SMILES OC(=O)c1nc2n(n1)c1cc(ccc1[n-]c2=[OH+])[N+]([O-])=O Show InChI InChI=1S/C10H5N5O5/c16-9-8-12-7(10(17)18)13-14(8)6-3-4(15(19)20)1-2-5(6)11-9/h1-3H,(H2,11,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078506 (8-Chloro-6-nitro-4-oxo-4,5-dihydro-[1,2,4]triazolo...) Show SMILES OC(=O)c1nc2n(n1)c1cc(Cl)cc([N+]([O-])=O)c1[nH]c2=O Show InChI InChI=1S/C10H4ClN5O5/c11-3-1-4-6(5(2-3)16(20)21)12-9(17)8-13-7(10(18)19)14-15(4)8/h1-2H,(H,12,17)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50078509 (7-Amino-4-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]qu...) Show SMILES CCOC(=O)c1nc2n(n1)c1ccc(N)cc1[nH]c2=O Show InChI InChI=1S/C12H11N5O3/c1-2-20-12(19)9-15-10-11(18)14-7-5-6(13)3-4-8(7)17(10)16-9/h3-5H,2,13H2,1H3,(H,14,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Universita' di Firenze Curated by ChEMBL					Assay Description Functional antagonism at the N-methyl-D-aspartate glutamate receptor 1 was demonstrated by the ability to inhibit the binding of thechannel-blocking ...				J Med Chem 42: 2478-84 (1999) Article DOI: 10.1021/jm981102r BindingDB Entry DOI: 10.7270/Q20K27R0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252427 ((R,S)-amino-(1-hydroxy-4-propyl-pyrazol-3-yl)-acet...) Show SMILES CCCc1cnn(O)c1C(N)C(O)=O Show InChI InChI=1S/C8H13N3O3/c1-2-3-5-4-10-11(14)7(5)6(9)8(12)13/h4,6,14H,2-3,9H2,1H3,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252433 ((R,S)-amino-(1-hydroxy-4-chloro-pyrazol-3-yl)-acet...) Show SMILES NC(C(O)=O)c1c(Cl)cnn1O Show InChI InChI=1S/C5H6ClN3O3/c6-2-1-8-9(12)4(2)3(7)5(10)11/h1,3,12H,7H2,(H,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.49E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp elect...				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50252433 ((R,S)-amino-(1-hydroxy-4-chloro-pyrazol-3-yl)-acet...) Show SMILES NC(C(O)=O)c1c(Cl)cnn1O Show InChI InChI=1S/C5H6ClN3O3/c6-2-1-8-9(12)4(2)3(7)5(10)11/h1,3,12H,7H2,(H,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.52E+5	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Activity at rat NR1/NR2D receptor expressed in Xenopus oocytes assessed as effect on glutamate-induced current by two voltage clamp electrophysiology				J Med Chem 51: 4179-87 (2008) Article DOI: 10.1021/jm800025e BindingDB Entry DOI: 10.7270/Q28C9X5Q
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 55 total )  |  Next  |  Last  >>

Jump to: