Compile Data Set for Download or QSAR

Found 86 hits of ec50 data for polymerid = 49000646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414494 (CHEMBL564300) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccsc1)Cc1ccsc1 Show InChI InChI=1S/C14H13N3O2S2/c18-14(19)12-5-13(16-15-12)17(6-10-1-3-20-8-10)7-11-2-4-21-9-11/h1-5,8-9H,6-7H2,(H,15,16)(H,18,19)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414492 (CHEMBL564914) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccsc1)Cc1ccccc1 Show InChI InChI=1S/C16H15N3O2S/c20-16(21)14-8-15(18-17-14)19(10-13-6-7-22-11-13)9-12-4-2-1-3-5-12/h1-8,11H,9-10H2,(H,17,18)(H,20,21)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414513 (CHEMBL394468) Show SMILES OC(=O)c1ccc(NCC=C)nc1 Show InChI InChI=1S/C9H10N2O2/c1-2-5-10-8-4-3-7(6-11-8)9(12)13/h2-4,6H,1,5H2,(H,10,11)(H,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50384637 (CHEMBL2036951) Show SMILES FC(F)CCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C11H10F2N2O4/c12-6(13)3-1-2-5-4-7(16)19-10-8(5)9(17)14-11(18)15-10/h4,6H,1-3H2,(H2,14,15,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 3: 63-68 (2012) Article DOI: 10.1021/ml200243g BindingDB Entry DOI: 10.7270/Q29K4C8X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50384640 (CHEMBL2036954) Show SMILES O=c1cc(CCC2CCC2)c2c([nH]c(=O)[nH]c2=O)o1 Show InChI InChI=1S/C13H14N2O4/c16-9-6-8(5-4-7-2-1-3-7)10-11(17)14-13(18)15-12(10)19-9/h6-7H,1-5H2,(H2,14,15,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	67	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 3: 63-68 (2012) Article DOI: 10.1021/ml200243g BindingDB Entry DOI: 10.7270/Q29K4C8X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50384612 (CHEMBL2036958) Show SMILES CC1(CCCc2cc(=O)oc3[nH]c(=O)[nH]c(=O)c23)CC1 Show InChI InChI=1S/C14H16N2O4/c1-14(5-6-14)4-2-3-8-7-9(17)20-12-10(8)11(18)15-13(19)16-12/h7H,2-6H2,1H3,(H2,15,16,18,19)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 3: 63-68 (2012) Article DOI: 10.1021/ml200243g BindingDB Entry DOI: 10.7270/Q29K4C8X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50384641 (CHEMBL2036955) Show SMILES O=c1cc(CCCC2CC2)c2c([nH]c(=O)[nH]c2=O)o1 Show InChI InChI=1S/C13H14N2O4/c16-9-6-8(3-1-2-7-4-5-7)10-11(17)14-13(18)15-12(10)19-9/h6-7H,1-5H2,(H2,14,15,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 3: 63-68 (2012) Article DOI: 10.1021/ml200243g BindingDB Entry DOI: 10.7270/Q29K4C8X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414491 (CHEMBL559204) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccsc1)Cc1cccs1 Show InChI InChI=1S/C14H13N3O2S2/c18-14(19)12-6-13(16-15-12)17(7-10-3-5-20-9-10)8-11-2-1-4-21-11/h1-6,9H,7-8H2,(H,15,16)(H,18,19)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	141	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208135 ((+)-5-methyl-5-(5-methyl-thiophen-3-yl)-4-oxo-4,5-...) Show SMILES Cc1cc(cs1)C1(C)OC(=CC1=O)C(O)=O |c:10| Show InChI InChI=1S/C11H10O4S/c1-6-3-7(5-16-6)11(2)9(12)4-8(15-11)10(13)14/h3-5H,1-2H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50384616 (CHEMBL2036813) Show SMILES CCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C11H12N2O4/c1-2-3-4-6-5-7(14)17-10-8(6)9(15)12-11(16)13-10/h5H,2-4H2,1H3,(H2,12,13,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 3: 63-68 (2012) Article DOI: 10.1021/ml200243g BindingDB Entry DOI: 10.7270/Q29K4C8X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475630 (CHEMBL382096) Show SMILES COCC(C)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H13N3O3/c1-7(6-17-2)14-10-4-3-8(11(15)16)5-9(10)12-13-14/h3-5,7H,6H2,1-2H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475626 (CHEMBL372727) Show SMILES CC(C)(C)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H13N3O2/c1-11(2,3)14-9-5-4-7(10(15)16)6-8(9)12-13-14/h4-6H,1-3H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	257	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475631 (CHEMBL202351) Show SMILES CCOCCn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H13N3O3/c1-2-17-6-5-14-10-4-3-8(11(15)16)7-9(10)12-13-14/h3-4,7H,2,5-6H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	257	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414495 (CHEMBL562675) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1cccs1)Cc1cccs1 Show InChI InChI=1S/C14H13N3O2S2/c18-14(19)12-7-13(16-15-12)17(8-10-3-1-5-20-10)9-11-4-2-6-21-11/h1-7H,8-9H2,(H,15,16)(H,18,19)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	257	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208140 (5-methyl-5-(5-methyl-thiophen-2-yl)-4-oxo-4,5-dihy...) Show SMILES Cc1ccc(s1)C1(C)OC(=CC1=O)C(O)=O |c:10| Show InChI InChI=1S/C11H10O4S/c1-6-3-4-9(16-6)11(2)8(12)5-7(15-11)10(13)14/h3-5H,1-2H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475629 (CHEMBL201048) Show SMILES CCCCCn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C12H15N3O2/c1-2-3-4-7-15-11-6-5-9(12(16)17)8-10(11)13-14-15/h5-6,8H,2-4,7H2,1H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	288	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50337038 (5-(3-cyclopropylpropyl)-2-(difluoromethyl)-3H-pyra...) Show SMILES FC(F)c1nc2oc(=O)cc(CCCC3CC3)c2c(=O)[nH]1 Show InChI InChI=1S/C14H14F2N2O3/c15-11(16)12-17-13(20)10-8(3-1-2-7-4-5-7)6-9(19)21-14(10)18-12/h6-7,11H,1-5H2,(H,17,18,20)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 2: 171-176 (2011) Article DOI: 10.1021/ml100251u BindingDB Entry DOI: 10.7270/Q2DZ08KX
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475639 (CHEMBL201409) Show SMILES CCSCCn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H13N3O2S/c1-2-17-6-5-14-10-4-3-8(11(15)16)7-9(10)12-13-14/h3-4,7H,2,5-6H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	302	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Agonist activity at HCA3 receptor (unknown origin) expressed in CHOK1 cells assessed as ERK1/2 phosphorylation by ELISA				Bioorg Med Chem 23: 4013-25 (2015) Article DOI: 10.1016/j.bmc.2015.02.018 BindingDB Entry DOI: 10.7270/Q22N558B
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475645 (CHEMBL202157) Show SMILES COCCn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C10H11N3O3/c1-16-5-4-13-9-3-2-7(10(14)15)6-8(9)11-12-13/h2-3,6H,4-5H2,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475637 (CHEMBL202206) Show SMILES CCC(C)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H13N3O2/c1-3-7(2)14-10-5-4-8(11(15)16)6-9(10)12-13-14/h4-7H,3H2,1-2H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	331	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50241028 (1-Isopropyl-1H-benzotriazole-5-carboxylic acid | 1...) Show SMILES CC(C)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C10H11N3O2/c1-6(2)13-9-4-3-7(10(14)15)5-8(9)11-12-13/h3-6H,1-2H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475635 (CHEMBL202586) Show SMILES CCCCn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H13N3O2/c1-2-3-6-14-10-5-4-8(11(15)16)7-9(10)12-13-14/h4-5,7H,2-3,6H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	692	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50220833 (5-(5-propyl-1H-pyrazol-3-yl)-1H-tetrazole | CHEMBL...) Show SMILES CCCc1cc(n[nH]1)-c1nnn[nH]1 Show InChI InChI=1S/C7H10N6/c1-2-3-5-4-6(9-8-5)7-10-12-13-11-7/h4H,2-3H2,1H3,(H,8,9)(H,10,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	724	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50220833 (5-(5-propyl-1H-pyrazol-3-yl)-1H-tetrazole | CHEMBL...) Show SMILES CCCc1cc(n[nH]1)-c1nnn[nH]1 Show InChI InChI=1S/C7H10N6/c1-2-3-5-4-6(9-8-5)7-10-12-13-11-7/h4H,2-3H2,1H3,(H,8,9)(H,10,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	724	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414499 (CHEMBL561920) Show SMILES OC(=O)c1cc([nH]n1)N(Cc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C18H17N3O2/c22-18(23)16-11-17(20-19-16)21(12-14-7-3-1-4-8-14)13-15-9-5-2-6-10-15/h1-11H,12-13H2,(H,19,20)(H,22,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	851	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475633 (CHEMBL440217) Show SMILES CCn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C9H9N3O2/c1-2-12-8-4-3-6(9(13)14)5-7(8)10-11-12/h3-5H,2H2,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	891	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475638 (CHEMBL201724) Show SMILES OC(=O)c1ccc2n(nnc2c1)C1CCCC1 Show InChI InChI=1S/C12H13N3O2/c16-12(17)8-5-6-11-10(7-8)13-14-15(11)9-3-1-2-4-9/h5-7,9H,1-4H2,(H,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50337024 (2-(difluoromethyl)-5-(3-(1-methylcyclopropyl)propy...) Show SMILES CC1(CCCc2cc(=O)oc3nc([nH]c(=O)c23)C(F)F)CC1 Show InChI InChI=1S/C15H16F2N2O3/c1-15(5-6-15)4-2-3-8-7-9(20)22-14-10(8)13(21)18-12(19-14)11(16)17/h7,11H,2-6H2,1H3,(H,18,19,21)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 2: 171-176 (2011) Article DOI: 10.1021/ml100251u BindingDB Entry DOI: 10.7270/Q2DZ08KX
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50384634 (CHEMBL2036948) Show SMILES CC(C)CCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C12H14N2O4/c1-6(2)3-4-7-5-8(15)18-11-9(7)10(16)13-12(17)14-11/h5-6H,3-4H2,1-2H3,(H2,13,14,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR109b				ACS Med Chem Lett 3: 63-68 (2012) Article DOI: 10.1021/ml200243g BindingDB Entry DOI: 10.7270/Q29K4C8X
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208137 ((+)-5-(5-bromo-thiophen-3-yl)-5-methyl-4-oxo-4,5-d...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1csc(Br)c1 |c:3| Show InChI InChI=1S/C10H7BrO4S/c1-10(5-2-8(11)16-4-5)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208137 ((+)-5-(5-bromo-thiophen-3-yl)-5-methyl-4-oxo-4,5-d...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1csc(Br)c1 |c:3| Show InChI InChI=1S/C10H7BrO4S/c1-10(5-2-8(11)16-4-5)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208122 ((+)-5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1csc(Cl)c1 |c:3| Show InChI InChI=1S/C10H7ClO4S/c1-10(5-2-8(11)16-4-5)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208122 ((+)-5-(5-chloro-thiophen-3-yl)-5-methyl-4-oxo-4,5-...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1csc(Cl)c1 |c:3| Show InChI InChI=1S/C10H7ClO4S/c1-10(5-2-8(11)16-4-5)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP production				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208134 (5-methyl-5-(4-methyl-thiophen-2-yl)-4-oxo-4,5-dihy...) Show SMILES Cc1csc(c1)C1(C)OC(=CC1=O)C(O)=O |c:10| Show InChI InChI=1S/C11H10O4S/c1-6-3-9(16-5-6)11(2)8(12)4-7(15-11)10(13)14/h3-5H,1-2H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475642 (CHEMBL201513) Show SMILES Cn1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C8H7N3O2/c1-11-7-3-2-5(8(12)13)4-6(7)9-10-11/h2-4H,1H3,(H,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475640 (CHEMBL380939) Show SMILES OC(=O)c1ccc2n(nnc2c1)C1CC1 Show InChI InChI=1S/C10H9N3O2/c14-10(15)6-1-4-9-8(5-6)11-12-13(9)7-2-3-7/h1,4-5,7H,2-3H2,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475643 (CHEMBL370386) Show SMILES CCC(CC)n1nnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C12H15N3O2/c1-3-9(4-2)15-11-6-5-8(12(16)17)7-10(11)13-14-15/h5-7,9H,3-4H2,1-2H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475641 (CHEMBL440041) Show SMILES OC(=O)c1ccc2n(nnc2c1)C1CCC1 Show InChI InChI=1S/C11H11N3O2/c15-11(16)7-4-5-10-9(6-7)12-13-14(10)8-2-1-3-8/h4-6,8H,1-3H2,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50220853 (5-(5-cyclopropyl-1H-pyrazol-3-yl)-1H-tetrazole | C...) Show SMILES C1CC1c1cc(n[nH]1)-c1nnn[nH]1 Show InChI InChI=1S/C7H8N6/c1-2-4(1)5-3-6(9-8-5)7-10-12-13-11-7/h3-4H,1-2H2,(H,8,9)(H,10,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50220853 (5-(5-cyclopropyl-1H-pyrazol-3-yl)-1H-tetrazole | C...) Show SMILES C1CC1c1cc(n[nH]1)-c1nnn[nH]1 Show InChI InChI=1S/C7H8N6/c1-2-4(1)5-3-6(9-8-5)7-10-12-13-11-7/h3-4H,1-2H2,(H,8,9)(H,10,11,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109b expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50475632 (CHEMBL382863) Show SMILES CC(C)n1cnc2cc(ccc12)C(O)=O Show InChI InChI=1S/C11H12N2O2/c1-7(2)13-6-12-9-5-8(11(14)15)3-4-10(9)13/h3-7H,1-2H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a
TBA Curated by PDSP Ki Database					Assay Description Agonistic activity at GPR109b by cAMP whole cell assay				J Med Chem 49: 1227-30 (2006) Article DOI: 10.1021/jm051099t BindingDB Entry DOI: 10.7270/Q2SF2ZZ4
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208116 (5-(5-chloro-thiophen-2-yl)-5-methyl-4-oxo-4,5-dihy...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccc(Cl)s1 |c:3| Show InChI InChI=1S/C10H7ClO4S/c1-10(7-2-3-8(11)16-7)6(12)4-5(15-10)9(13)14/h2-4H,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414502 (CHEMBL561720) Show SMILES OC(=O)c1cc([nH]n1)N(CC1CC1)CC1CC1 Show InChI InChI=1S/C12H17N3O2/c16-12(17)10-5-11(14-13-10)15(6-8-1-2-8)7-9-3-4-9/h5,8-9H,1-4,6-7H2,(H,13,14)(H,16,17)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208110 (5-methyl-5-(4-bromo-thiophen-2-yl)-4-oxo-4,5-dihyd...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1cc(Br)cs1 |c:3| Show InChI InChI=1S/C10H7BrO4S/c1-10(8-2-5(11)4-16-8)7(12)3-6(15-10)9(13)14/h2-4H,1H3,(H,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at N-terminal HA-tagged GPR109b receptor transfected in forskolin-stimulated cells assessed as cAMP accumulation by flashplate assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208139 (5-methyl-4-oxo-5-thiophen-3-yl-4,5-dihydro-furan-2...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccsc1 |c:3| Show InChI InChI=1S/C10H8O4S/c1-10(6-2-3-15-5-6)8(11)4-7(14-10)9(12)13/h2-5H,1H3,(H,12,13)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208138 ((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...) Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:3| Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50414506 (CHEMBL553415) Show SMILES CCC(C)Nc1cc(n[nH]1)C(O)=O Show InChI InChI=1S/C8H13N3O2/c1-3-5(2)9-7-4-6(8(12)13)10-11-7/h4-5H,3H2,1-2H3,(H,12,13)(H2,9,10,11)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at GPR109b receptor transfected in CHOK1 cells assessed as inhibition of forskolin-induced cAMP generation by HTRF assay				Bioorg Med Chem Lett 19: 4207-9 (2009) Article DOI: 10.1016/j.bmcl.2009.05.108 BindingDB Entry DOI: 10.7270/Q2GF0TJJ
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 3 (Homo sapiens (Human))	BDBM50208125 (5-ethyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxy...) Show SMILES CCC1(OC(=CC1=O)C(O)=O)c1ccccc1 |c:4| Show InChI InChI=1S/C13H12O4/c1-2-13(9-6-4-3-5-7-9)11(14)8-10(17-13)12(15)16/h3-8H,2H2,1H3,(H,15,16)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Activity at GPR109b in CHO cells assessed as inhibition of forskolin-induced cAMP generation				J Med Chem 50: 1445-8 (2007) Article DOI: 10.1021/jm070022x BindingDB Entry DOI: 10.7270/Q2BK1C1Z
					More data for this Ligand-Target Pair

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