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Compile Data Set for Download or QSAR

Found 4 hits of ic50 data for polymerid = 49000646   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50208138
PNG
((+)-acifran | (-)-acifran | 5-Methyl-4-oxo-5-pheny...)
Show SMILES CC1(OC(=CC1=O)C(O)=O)c1ccccc1
Show InChI InChI=1S/C12H10O4/c1-12(8-5-3-2-4-6-8)10(13)7-9(16-12)11(14)15/h2-7H,1H3,(H,14,15)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Activity at GPR109b assessed as inhibition of forskolin-stimulated cAMP production


J Med Chem 51: 7653-62 (2008)

More data for this
Ligand-Target Pair
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50325913
PNG
(2-(3-(2-chlorophenoxy)propoxy)pyrido[2,3-d]pyrimid...)
Show SMILES Clc1ccccc1OCCCOc1nc2ncccc2c(=O)[nH]1
Show InChI InChI=1S/C16H14ClN3O3/c17-12-6-1-2-7-13(12)22-9-4-10-23-16-19-14-11(15(21)20-16)5-3-8-18-14/h1-3,5-8H,4,9-10H2,(H,18,19,20,21)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.30E+4n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of radioligand from human GPR109B


Bioorg Med Chem Lett 20: 5426-30 (2010)

More data for this
Ligand-Target Pair
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50325899
PNG
(2-(trifluoromethyl)pyrido[2,3-d]pyrimidin-4(3H)-on...)
Show SMILES FC(F)(F)c1nc2ncccc2c(=O)[nH]1
Show InChI InChI=1S/C8H4F3N3O/c9-8(10,11)7-13-5-4(6(15)14-7)2-1-3-12-5/h1-3H,(H,12,13,14,15)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of radioligand from human GPR109B


Bioorg Med Chem Lett 20: 5426-30 (2010)

More data for this
Ligand-Target Pair
HM74 nicotinic acid GPCR


(Homo sapiens (Human))
BDBM50325922
PNG
(2-((4-fluorophenethyloxy)methyl)pyrido[2,3-d]pyrim...)
Show SMILES Fc1ccc(CCOCc2nc3ncccc3c(=O)[nH]2)cc1
Show InChI InChI=1S/C16H14FN3O2/c17-12-5-3-11(4-6-12)7-9-22-10-14-19-15-13(16(21)20-14)2-1-8-18-15/h1-6,8H,7,9-10H2,(H,18,19,20,21)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Displacement of radioligand from human GPR109B


Bioorg Med Chem Lett 20: 5426-30 (2010)

More data for this
Ligand-Target Pair