Compile Data Set for Download or QSAR

Found 11 hits of ic50 for UniProtKB: P37289   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50355549 (CHEMBL1910324) Show SMILES CC[C@@H](C)[C@@H](N)C(=O)N[C@H](CC(C)C)C(=O)NCC(=O)N[C@H](Cc1cnc[nH]1)C(=O)N[C@H](CCCNC(N)=O)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](CCCCN)C(O)=O |r| Show InChI InChI=1S/C45H71N13O13/c1-5-25(4)37(47)43(68)58-31(17-24(2)3)38(63)51-22-35(60)53-33(19-27-21-49-23-52-27)41(66)54-29(10-8-16-50-45(48)71)39(64)57-34(20-36(61)62)42(67)56-32(18-26-11-13-28(59)14-12-26)40(65)55-30(44(69)70)9-6-7-15-46/h11-14,21,23-25,29-34,37,59H,5-10,15-20,22,46-47H2,1-4H3,(H,49,52)(H,51,63)(H,53,60)(H,54,66)(H,55,65)(H,56,67)(H,57,64)(H,58,68)(H,61,62)(H,69,70)(H3,48,50,71)/t25-,29-,30-,31-,32-,33-,34-,37-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
McGill University Health Center Research Institute Curated by ChEMBL					Assay Description Antagonist activity at FP receptor in bovine myometrial strip assessed as inhibition of PGF-2alpha-induced contractions				J Med Chem 54: 6085-97 (2011) Article DOI: 10.1021/jm200608k BindingDB Entry DOI: 10.7270/Q2S75GQ8
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50035622 ((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r| Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50020299 ((R-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-7-phenyl-h...) Show SMILES O[C@@H](CCCCc1ccccc1)\C=C\C1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C25H36O5/c26-20(13-9-8-12-19-10-4-3-5-11-19)16-17-22-21(23(27)18-24(22)28)14-6-1-2-7-15-25(29)30/h1,3-6,10-11,16-17,20-24,26-28H,2,7-9,12-15,18H2,(H,29,30)/b6-1-,17-16+/t20-,21+,22?,23-,24+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards PGF-2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes (BCLM)				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50405735 (CHEMBL2114230) Show SMILES O[C@H](CCCCc1ccccc1)\C=C\C1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C25H36O5/c26-20(13-9-8-12-19-10-4-3-5-11-19)16-17-22-21(23(27)18-24(22)28)14-6-1-2-7-15-25(29)30/h1,3-6,10-11,16-17,20-24,26-28H,2,7-9,12-15,18H2,(H,29,30)/b6-1-,17-16+/t20-,21-,22?,23+,24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards PGF-2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes (BCLM)				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50020301 ((R-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-7-phenyl-h...) Show SMILES COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)C1\C=C\[C@@H](O)CCCCc1ccccc1 Show InChI InChI=1S/C26H38O5/c1-31-26(30)16-8-3-2-7-15-22-23(25(29)19-24(22)28)18-17-21(27)14-10-9-13-20-11-5-4-6-12-20/h2,4-7,11-12,17-18,21-25,27-29H,3,8-10,13-16,19H2,1H3/b7-2-,18-17+/t21-,22+,23?,24-,25+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards PGF-2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes (BCLM)				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50020302 ((S-isomer)7-{2-[5-(4-Azido-phenyl)-3-hydroxy-pent-...) Show SMILES O[C@@H](CCc1ccc(cc1)N=[N+]=[N-])\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C23H31N3O5/c24-26-25-17-10-7-16(8-11-17)9-12-18(27)13-14-20-19(21(28)15-22(20)29)5-3-1-2-4-6-23(30)31/h1,3,7-8,10-11,13-14,18-22,27-29H,2,4-6,9,12,15H2,(H,30,31)/b3-1-,14-13+/t18-,19+,20+,21-,22+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50020303 ((R-isomer)7-{2-[5-(4-Azido-3-iodo-phenyl)-3-hydrox...) Show SMILES O[C@@H](CCc1ccc(N=[N+]=[N-])c(I)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C23H30IN3O5/c24-19-13-15(8-12-20(19)26-27-25)7-9-16(28)10-11-18-17(21(29)14-22(18)30)5-3-1-2-4-6-23(31)32/h1,3,8,10-13,16-18,21-22,28-30H,2,4-7,9,14H2,(H,31,32)/b3-1-,11-10+/t16-,17+,18+,21-,22+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50405737 (CHEMBL2114229) Show SMILES COC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)C1\C=C\[C@H](O)CCCCc1ccccc1 Show InChI InChI=1S/C26H38O5/c1-31-26(30)16-8-3-2-7-15-22-23(25(29)19-24(22)28)18-17-21(27)14-10-9-13-20-11-5-4-6-12-20/h2,4-7,11-12,17-18,21-25,27-29H,3,8-10,13-16,19H2,1H3/b7-2-,18-17+/t21-,22-,23?,24+,25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards PGF-2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes (BCLM)				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50405736 (CHEMBL2114224) Show SMILES O[C@H](CCc1ccc(N=[N+]=[N-])c(I)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C23H30IN3O5/c24-19-13-15(8-12-20(19)26-27-25)7-9-16(28)10-11-18-17(21(29)14-22(18)30)5-3-1-2-4-6-23(31)32/h1,3,8,10-13,16-18,21-22,28-30H,2,4-7,9,14H2,(H,31,32)/b3-1-,11-10+/t16-,17-,18-,21+,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50020304 ((R-isomer)7-{2-[4-(4-Azido-2-hydroxy-phenoxy)-3-hy...) Show SMILES O[C@@H](COc1ccc(cc1O)N=[N+]=[N-])\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C22H29N3O7/c23-25-24-14-7-10-21(20(29)11-14)32-13-15(26)8-9-17-16(18(27)12-19(17)28)5-3-1-2-4-6-22(30)31/h1,3,7-11,15-19,26-29H,2,4-6,12-13H2,(H,30,31)/b3-1-,9-8+/t15-,16-,17-,18+,19-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (BOVINE)	BDBM50020306 ((S-isomer)7-{2-[5-(4-Azido-2-hydroxy-phenyl)-3-hyd...) Show SMILES O[C@@H](CCc1ccc(cc1O)N=[N+]=[N-])\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C23H31N3O6/c24-26-25-16-9-7-15(20(28)13-16)8-10-17(27)11-12-19-18(21(29)14-22(19)30)5-3-1-2-4-6-23(31)32/h1,3,7,9,11-13,17-19,21-22,27-30H,2,4-6,8,10,14H2,(H,31,32)/b3-1-,12-11+/t17-,18+,19+,21-,22+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...				J Med Chem 32: 256-64 (1989) BindingDB Entry DOI: 10.7270/Q23F4Q7C
					More data for this Ligand-Target Pair