Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421905 (CHEMBL553265) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50382166 (CHEMBL2023825) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens Curated by ChEMBL | Assay Description Displacement of [3H](+)pentazocine from sigma-1 receptor expressed in human Jurkat cell membranes after 2 hrs by liquid scintillation spectroscopy | Bioorg Med Chem 20: 3323-31 (2012) Article DOI: 10.1016/j.bmc.2012.03.038 BindingDB Entry DOI: 10.7270/Q20V8DT0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040283 (3-Chloro-6-dimethylamino-6-methyl-8-phenyl-5,6,7,8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligand | J Med Chem 36: 2542-51 (1993) BindingDB Entry DOI: 10.7270/Q2C53MGM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421907 (CHEMBL540274) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.324 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50036730 (3-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Curated by ChEMBL | Assay Description Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]-haloperidol in the presence of 25 nM unlabeled spiperone | J Med Chem 36: 3923-8 (1994) BindingDB Entry DOI: 10.7270/Q2H13122 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50054728 (1,4-Bis-(3-phenyl-propyl)-piperazine | CHEMBL34640...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assay | J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040287 ((1R,3S)Dimethyl-(2-methyl-4-phenyl-1,2,3,4-tetrahy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description Binding affinity against dopamine receptor D1 from rat striatal homogenates, using [3H]SCH-23390 as radioligand. | J Med Chem 36: 2542-51 (1993) BindingDB Entry DOI: 10.7270/Q2C53MGM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040287 ((1R,3S)Dimethyl-(2-methyl-4-phenyl-1,2,3,4-tetrahy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligand | J Med Chem 36: 2542-51 (1993) BindingDB Entry DOI: 10.7270/Q2C53MGM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM86029 (trans-H2-PAT(+)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM86029 (trans-H2-PAT(+)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.525 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040282 (CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.708 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040282 (CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.710 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421946 (CHEMBL1788383) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.724 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50172914 ((S)-2-(2-Piperidin-1-yl-ethyl)-3-thioxo-2,3,10,10a...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Lille II Curated by ChEMBL | Assay Description Inhibitory concentration against opioid receptor sigma 1 of guinea pig cerebral cortex using [3H]-(+)-pentazocine upon incubation for 150 minutes at ... | Bioorg Med Chem Lett 15: 4833-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.040 BindingDB Entry DOI: 10.7270/Q2PN9553 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50282973 (4-Fluoro-N-{1-(4-fluoro-naphthalen-1-yl)-4-[4-(5-f...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | >1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brain | Bioorg Med Chem Lett 4: 1941-1946 (1994) Article DOI: 10.1016/S0960-894X(01)80539-4 BindingDB Entry DOI: 10.7270/Q28C9W6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM22165 (1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421940 (CHEMBL62770) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50170657 (1''-butyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421930 (CHEMBL1788382) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421906 (CHEMBL544281) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50170660 (CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description In vitro binding affinity at Sigma opioid receptors on guinea pig brain membranes by [3H]3-PPP displacement. | J Med Chem 42: 3965-70 (1999) BindingDB Entry DOI: 10.7270/Q2PR7WQ7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421932 (CHEMBL1743999) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421939 (CHEMBL1744003) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040282 (CHEMBL317029 | CHEMBL545249 | cis-3-Chloro-6-dimet...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description Binding affinity against sigma receptor from guinea pig brain (minus cerebellum) homogenates, using the novel [3H]-(+/-)-4 as radioligand | J Med Chem 36: 2542-51 (1993) BindingDB Entry DOI: 10.7270/Q2C53MGM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421895 (CHEMBL555890) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50081380 (CHEMBL553962 | [1-(4-Methoxy-3-phenethyloxy-benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description In vitro binding affinity at Sigma opioid receptors on guinea pig brain membranes by [3H]3-PPP displacement. | J Med Chem 42: 3965-70 (1999) BindingDB Entry DOI: 10.7270/Q2PR7WQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421954 (CHEMBL1744015) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421951 (CHEMBL1744002) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421903 (CHEMBL545212) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421913 (CHEMBL545682) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50081366 (CHEMBL540331 | [1-(4-Methoxy-3-phenethyloxy-benzyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description In vitro binding affinity at Sigma opioid receptors on guinea pig brain membranes by [3H]3-PPP displacement. | J Med Chem 42: 3965-70 (1999) BindingDB Entry DOI: 10.7270/Q2PR7WQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421899 (CHEMBL545688) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421945 (CHEMBL1744017) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50003743 ((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Affinity of compound to Sigma opioid receptor labelled with [3H](+)-3-PPP | J Med Chem 33: 3100-10 (1990) BindingDB Entry DOI: 10.7270/Q2348KZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421915 (CHEMBL544748) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50282974 (CHEMBL58283 | N-{1-Cyclohexyl-4-[4-(5-fluoro-pyrim...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | >2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro binding affinity of the compound towards sigma receptor by the displacement of [3H]-PPP from guinea pig brain | Bioorg Med Chem Lett 4: 1941-1946 (1994) Article DOI: 10.1016/S0960-894X(01)80539-4 BindingDB Entry DOI: 10.7270/Q28C9W6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421926 (CHEMBL541052) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50081369 (CHEMBL128860 | CHEMBL541091 | [1-(4-Methoxy-3-phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Company Ltd. Curated by ChEMBL | Assay Description In vitro binding affinity at Sigma opioid receptors on guinea pig brain membranes by [3H]3-PPP displacement. | J Med Chem 42: 3965-70 (1999) BindingDB Entry DOI: 10.7270/Q2PR7WQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421894 (CHEMBL555581) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Université de Lille II Curated by ChEMBL | Assay Description Inhibitory activity against opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at... | Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50172886 ((S)-2-[3-(Methyl-phenethyl-amino)-propyl]-10,10a-d...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Université de Lille II Curated by ChEMBL | Assay Description Inhibitory activity against opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at... | Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Université de Lille II Curated by ChEMBL | Assay Description Inhibitory concentration against opioid receptor sigma 1 of guinea pig cerebral cortex using [3H]-(+)-pentazocine upon incubation for 150 minutes at ... | Bioorg Med Chem Lett 15: 4833-7 (2005) Article DOI: 10.1016/j.bmcl.2005.07.040 BindingDB Entry DOI: 10.7270/Q2PN9553 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421929 (CHEMBL544987) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50040292 (CHEMBL323287 | CHEMBL544309 | trans-Diethyl-(4-phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM79172 (2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenyli...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of North Carolina Curated by ChEMBL | Assay Description The compound was tested for affinity towards sigma-3 receptor | J Med Chem 37: 4109-17 (1995) BindingDB Entry DOI: 10.7270/Q2QF8V57 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421904 (CHEMBL553561) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421934 (CHEMBL1744000) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against sigma receptor by using [3H]-DTG ([3H]-6) as radioligand in guinea pig cerebellum. | J Med Chem 35: 2033-9 (1992) BindingDB Entry DOI: 10.7270/Q2GX4CVJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50172884 ((S)-2-(1-Benzyl-piperidin-4-yl)-10,10a-dihydro-5H-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Université de Lille II Curated by ChEMBL | Assay Description Inhibitory activity against Opioid receptor sigma 1 in guinea pig cerebral cortex using [3H]-(+)-pentazocine as radio ligand at pH 7.5 for 150 min at... | Bioorg Med Chem Lett 15: 4828-32 (2005) Article DOI: 10.1016/j.bmcl.2005.07.039 BindingDB Entry DOI: 10.7270/Q2TD9WW1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50421914 (CHEMBL543810) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL | Assay Description In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellum | J Med Chem 35: 2025-33 (1992) BindingDB Entry DOI: 10.7270/Q2MP54K8 | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 997 total ) | Next | Last >> |