BindingDB PrimarySearch

Found 13 hits of kd data for polymerid = 49000996
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50445185 (CHEMBL3103203) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Westf£lischen Wilhelms-Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [125I]N-IAC44 from sigma 1 receptor (unknown origin)				J Med Chem 56: 9809-19 (2013) Article DOI: 10.1021/jm400660u BindingDB Entry DOI: 10.7270/Q2QN688V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50445186 (CHEMBL3103202) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Westf£lischen Wilhelms-Universit£t M£nster Curated by ChEMBL					Assay Description Displacement of [125I]N-IACoc from sigma 1 receptor (unknown origin)				J Med Chem 56: 9809-19 (2013) Article DOI: 10.1021/jm400660u BindingDB Entry DOI: 10.7270/Q2QN688V
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Binding constant (Kd) for [3H]-DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 200 nM concentration of the compound				J Med Chem 45: 2662-5 (2002) BindingDB Entry DOI: 10.7270/Q2C24X46
University of Catania Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 \| DITOLYLGUANIDINE \| DTG \| Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C \|w:10.11\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Binding constant (Kd) for [3H]DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 5 uM BNIT				J Med Chem 45: 2662-5 (2002) BindingDB Entry DOI: 10.7270/Q2C24X46
University of Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 \| DITOLYLGUANIDINE \| DTG \| Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C \|w:10.11\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	13.6	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Binding constant (Kd) for [3H]DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 1 uM BNIT				J Med Chem 45: 2662-5 (2002) BindingDB Entry DOI: 10.7270/Q2C24X46
University of Catania Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	34.5	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Binding affinity to Sigma opioid receptor type 1 sites in guinea pig brain membranes at 0.1 uM of BNIT				J Med Chem 45: 2662-5 (2002) BindingDB Entry DOI: 10.7270/Q2C24X46
University of Catania Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM81982 (CAS_97-39-2 \| DITOLYLGUANIDINE \| DTG \| Di-o-tolylg...) Show SMILES Cc1ccccc1NC(N)=Nc1ccccc1C \|w:10.11\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	38.2	n/a	n/a	n/a	n/a	n/a
George Washington University Medical Center Curated by ChEMBL					Assay Description Binding affinity against MCF cells in the membrane preparation using radioligand binding assay.				J Med Chem 37: 1737-9 (1994) BindingDB Entry DOI: 10.7270/Q2VX0FJ7
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543315 (CHEMBL4642064) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543316 (CHEMBL4640674) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543317 (CHEMBL4638486) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543318 (CHEMBL4644063) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50543319 (CHEMBL4639260) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...				ACS Med Chem Lett 11: 1555-1561 (2020) Article DOI: 10.1021/acsmedchemlett.9b00314 BindingDB Entry DOI: 10.7270/Q2MK6HGT
Harvard Medical School Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50601684 (CHEMBL5169925) Show SMILES CNCCc1ccc(O)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jnatprod.1c00381 BindingDB Entry DOI: 10.7270/Q2KS6WKG
TBA					More data for this Ligand-Target Pair