BindingDB PrimarySearch

Found 3086 hits of ki data for polymerid = 49000996
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50398057 (CHEMBL2181924) Show SMILES FCCCc1ccc2n(CCN3CCCCCC3)c(=O)sc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars		0.00250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme				Citation and Details
TBA					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50146585 (CHEMBL3763396) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50145021 (1-Cyclohexyl-4-[4-(1,2,3,4-tetrahydro-naphthalen-1...) Show SMILES C(CCN1CCN(CC1)C1CCCCC1)CC1CCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.				J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50170652 ((2R,6S)-2,6-Dimethyl-4-tridecyl-morpholine \| CHEMB...) Show SMILES CCCCCCCCCCCCCN1C[C@H](C)O[C@H](C)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50038707 (1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brain				J Med Chem 37: 1964-70 (1994) BindingDB Entry DOI: 10.7270/Q2QZ2BMR
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50038707 (1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brain				J Med Chem 37: 1964-70 (1994) BindingDB Entry DOI: 10.7270/Q2QZ2BMR
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415166 (CHEMBL578825) Show SMILES O=C1CC(Sc2ccccc12)C1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	0.0525	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415165 (CHEMBL570795) Show SMILES C(N1CCC(CC1)C1CCc2ccccc2S1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0575	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415164 (CHEMBL570529) Show SMILES O=C1CC(Oc2ccccc12)C1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0661	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50144508 (4-Methyl-1-(5-phenyl-pentyl)-piperidine \| CHEMBL30...) Show SMILES CC1CCN(CCCCCc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligand				Bioorg Med Chem Lett 14: 2217-20 (2004) Article DOI: 10.1016/j.bmcl.2004.02.018 BindingDB Entry DOI: 10.7270/Q2R210T8
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50251208 (CHEMBL4088272) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme				Citation and Details
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50170654 ((+-)-cis-4-(3-(4-tert-butylphenyl)-2-methylpropyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Wisconsin School of Medicine and Public Health Curated by ChEMBL					Assay Description Displacement of (+)-[3H]pentazocine from sigma 1 receptor expressed in Saccharomyces cerevisiae WA0				Bioorg Med Chem 18: 4397-404 (2010) Article DOI: 10.1016/j.bmc.2010.04.078 BindingDB Entry DOI: 10.7270/Q20C4VZT
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415163 (CHEMBL571418) Show SMILES C(N1CCC2(CC1)OCc1ccccc1S2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0891	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50144518 (1-(5,5-Diphenyl-pentyl)-4-methyl-piperidine \| CHEM...) Show SMILES CC1CCN(CCCCC(c2ccccc2)c2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligand				Bioorg Med Chem Lett 14: 2217-20 (2004) Article DOI: 10.1016/j.bmcl.2004.02.018 BindingDB Entry DOI: 10.7270/Q2R210T8
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415162 (CHEMBL572294) Show SMILES C(N1CCC2(CC1)OCc1ccccc1O2)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0977	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415161 (CHEMBL570067) Show SMILES O=C1CC(Oc2ccccc12)C1CCN(CCc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50144512 (1-(5,5-Diphenyl-pent-4-enyl)-4-methyl-piperidine \|...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligand				Bioorg Med Chem Lett 14: 2217-20 (2004) Article DOI: 10.1016/j.bmcl.2004.02.018 BindingDB Entry DOI: 10.7270/Q2R210T8
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50065136 (CHEMBL81455 \| N-(2-Azepan-1-yl-ethyl)-4-iodo-N-met...) Show SMILES CN(CCN1CCCCCC1)S(=O)(=O)c1ccc(I)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041259 (CHEMBL19355 \| Phenethyl-(5-phenyl-pentyl)-amine) Show SMILES C(CCNCCc1ccccc1)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligand				Bioorg Med Chem Lett 14: 2217-20 (2004) Article DOI: 10.1016/j.bmcl.2004.02.018 BindingDB Entry DOI: 10.7270/Q2R210T8
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041259 (CHEMBL19355 \| Phenethyl-(5-phenyl-pentyl)-amine) Show SMILES C(CCNCCc1ccccc1)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000066 ((2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-eth...) Show SMILES CN(CCN1CCCCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50065134 (CHEMBL309983 \| N-(2-Azepan-1-yl-ethyl)-4-bromo-N-m...) Show SMILES CN(CCN1CCCCCC1)S(=O)(=O)c1ccc(Br)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The George Washington University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membranes				J Med Chem 41: 2445-50 (1998) Article DOI: 10.1021/jm9800447 BindingDB Entry DOI: 10.7270/Q27P8XHM
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041268 (Benzyl-methyl-(5-phenyl-pentyl)-amine \| CHEMBL1931...) Show SMILES CN(CCCCCc1ccccc1)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50170636 (2-[4-(3-Dibenzo[b,f]azepin-5-yl-propyl)-piperazin-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Innsbruck Curated by ChEMBL					Assay Description Affinity for sigma receptor type 1 of guinea pig using [3H]ifenprodil or (+)-[3H]pentazocine radioligand				J Med Chem 48: 4754-64 (2005) Article DOI: 10.1021/jm049073+ BindingDB Entry DOI: 10.7270/Q2639QHB
University of Innsbruck Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50415160 (CHEMBL571659) Show SMILES O=C1CC2(CCN(Cc3ccccc3)CC2)Oc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.209	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membrane				J Med Chem 53: 1261-9 (2010) Article DOI: 10.1021/jm901542q BindingDB Entry DOI: 10.7270/Q28K7B9S
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University College of Medicine Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranes				Bioorg Med Chem Lett 27: 2216-2220 (2017) Article DOI: 10.1016/j.bmcl.2017.03.030 BindingDB Entry DOI: 10.7270/Q2P84F1X
Drexel University College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50145029 (1-Cyclohexyl-4-(4-naphthalen-1-yl-butyl)-piperazin...) Show SMILES C(CCc1cccc2ccccc12)CN1CCN(CC1)C1CCCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.				J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041246 (CHEMBL19544 \| Methyl-phenethyl-(5-phenyl-pentyl)-a...) Show SMILES CN(CCCCCc1ccccc1)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity for Sigma receptor type 1,using [3H]-(+)-pentazocine as radioligand				Bioorg Med Chem Lett 14: 2217-20 (2004) Article DOI: 10.1016/j.bmcl.2004.02.018 BindingDB Entry DOI: 10.7270/Q2R210T8
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041246 (CHEMBL19544 \| Methyl-phenethyl-(5-phenyl-pentyl)-a...) Show SMILES CN(CCCCCc1ccccc1)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041277 ((5-Cyclohexyl-pentyl)-dimethyl-amine \| CHEMBL20036) Show SMILES CN(C)CCCCCC1CCCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000068 (CHEMBL142700 \| [2-(3,4-Dichloro-phenyl)-ethyl]-met...) Show SMILES CN(CCN1CCCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50038717 (1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 3-(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Albany Molecular Research Curated by ChEMBL					Assay Description Affinity at sigma-1 site by inhibition of [3H](+)-pentazocine (PENT) binding in guinea pig brain				J Med Chem 37: 1964-70 (1994) BindingDB Entry DOI: 10.7270/Q2QZ2BMR
Albany Molecular Research Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041257 ((5-Phenyl-pentyl)-(3-phenyl-propyl)-amine \| CHEMBL...) Show SMILES C(CCNCCCc1ccccc1)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041275 (CHEMBL20348 \| Methyl-(5-phenyl-pentyl)-propyl-amin...) Show SMILES CCCN(C)CCCCCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50037480 ((6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50159013 (3-(4-Benzyl-piperazin-1-ylmethyl)-3,4-dihydro-2H-n...) Show SMILES O=C1CC(CN2CCN(Cc3ccccc3)CC2)Cc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					Assay Description Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocine				J Med Chem 48: 266-73 (2005) Article DOI: 10.1021/jm049433t BindingDB Entry DOI: 10.7270/Q2JH3MZW
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50159021 (1-Benzyl-4-chroman-3-ylmethyl-piperazine \| 1-benzy...) Show SMILES C(C1COc2ccccc2C1)N1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					Assay Description Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocine				J Med Chem 48: 266-73 (2005) Article DOI: 10.1021/jm049433t BindingDB Entry DOI: 10.7270/Q2JH3MZW
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50159018 (1-Benzyl-4-chroman-2-ylmethyl-piperazine \| 1-benzy...) Show SMILES C(C1CCc2ccccc2O1)N1CCN(Cc2ccccc2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					Assay Description Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocine				J Med Chem 48: 266-73 (2005) Article DOI: 10.1021/jm049433t BindingDB Entry DOI: 10.7270/Q2JH3MZW
Universit£ di Modena and Reggio Emilia Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50145014 (1-Cyclohexyl-4-(5-methoxy-1,2,3,4-tetrahydro-napht...) Show SMILES COc1cccc2C(CN3CCN(CC3)C3CCCCC3)CCCc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.				J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000776 (1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperaz...) Show SMILES CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50068455 (CHEMBL342809 \| {4-Oxo-4-[4-(3-phenyl-propyl)-piper...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity was tested against sigma-1 receptor in guinea brain membranes.				J Med Chem 41: 4950-7 (1999) Article DOI: 10.1021/jm980143k BindingDB Entry DOI: 10.7270/Q2NG4PR0
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041243 (Benzyl-(5-phenyl-pentyl)-amine \| CHEMBL19315) Show SMILES C(CCNCc1ccccc1)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested for [3H]-(+)-pentazocine binding to sigma-1 receptor in guinea pig brain membrane				J Med Chem 36: 3929-36 (1994) BindingDB Entry DOI: 10.7270/Q2C828CS
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 \| [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor from guinea pig brain, using [3H](+)-3-PPP as radioligand.				J Med Chem 35: 2221-30 (1992) BindingDB Entry DOI: 10.7270/Q24B31ZD
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 \| [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against [3H]-3-PPP labelled sigma sites				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 \| [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]-(+) -3PPP from sigma receptor in guinea pig brain membranes				J Med Chem 35: 38-47 (1992) BindingDB Entry DOI: 10.7270/Q2BP01RW
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50128107 (1-[2-(4-Chloro-phenoxy)-1-methyl-ethyl]-4-methyl-p...) Show SMILES C[C@@H](COc1ccc(Cl)cc1)N1CCC(C)CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Inhibition of [3H]pentazocine binding to Sigma receptor type 1 in guinea pig brain membrane without cerebellum				J Med Chem 46: 2117-24 (2003) Article DOI: 10.1021/jm021014d BindingDB Entry DOI: 10.7270/Q2DF6RZR
Universit£ di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50145019 (1-Cyclohexyl-4-[3-(6-methoxy-1,2,3,4-tetrahydro-na...) Show SMILES COc1ccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Bari Curated by ChEMBL					Assay Description In vitro binding afinity at opioid sigma-1 receptorin guinea pig brain membranes by (+)-[3H]-pentazocine displacement.				J Med Chem 47: 2308-17 (2004) Article DOI: 10.1021/jm031026e BindingDB Entry DOI: 10.7270/Q2DN44HS
Università di Bari Curated by ChEMBL					More data for this Ligand-Target Pair

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