Compile Data Set for Download or QSAR

Found 218 hits of ec50 for UniProtKB: Q9UKP6   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558696 (CHEMBL4777970) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.450	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558700 (CHEMBL4748168) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	0.830	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50378580 (CHEMBL437430) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O Show InChI InChI=1S/C64H85N13O18S2/c1-33(2)52(64(94)95)75-61(91)48-32-97-96-31-47(73-59(89)46(29-51(82)83)72-62(92)49-17-11-25-77(49)63(93)53(34(3)78)76-54(84)40(66)22-23-50(80)81)60(90)70-43(26-35-12-5-4-6-13-35)56(86)71-45(28-37-30-67-41-15-8-7-14-39(37)41)58(88)68-42(16-9-10-24-65)55(85)69-44(57(87)74-48)27-36-18-20-38(79)21-19-36/h4-8,12-15,18-21,30,33-34,40,42-49,52-53,67,78-79H,9-11,16-17,22-29,31-32,65-66H2,1-3H3,(H,68,88)(H,69,85)(H,70,90)(H,71,86)(H,72,92)(H,73,89)(H,74,87)(H,75,91)(H,76,84)(H,80,81)(H,82,83)(H,94,95)/t34-,40+,42-,43-,44+,45+,46+,47-,48+,49-,52+,53+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09	n/a	n/a	n/a	n/a
PRISM Bio. Lab. Corporation Curated by ChEMBL					Assay Description Agonist activity at human GPR14 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem 17: 6742-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.058 BindingDB Entry DOI: 10.7270/Q2F47Q28
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558695 (CHEMBL4741230) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112107 (CHEMBL385616 | Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr...) Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](N)CCC(O)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(O)=O Show InChI InChI=1S/C59H78N12O17S2/c1-31(72)49(70-50(78)37(61)20-21-47(74)75)58(86)71-23-9-15-46(71)57(85)67-43(27-48(76)77)55(83)68-44(29-89)56(84)65-40(24-32-10-3-2-4-11-32)52(80)66-42(26-34-28-62-38-13-6-5-12-36(34)38)54(82)63-39(14-7-8-22-60)51(79)64-41(25-33-16-18-35(73)19-17-33)53(81)69-45(30-90)59(87)88/h2-6,10-13,16-19,28,31,37,39-46,49,62,72-73,89-90H,7-9,14-15,20-27,29-30,60-61H2,1H3,(H,63,82)(H,64,79)(H,65,84)(H,66,80)(H,67,85)(H,68,83)(H,69,81)(H,70,78)(H,74,75)(H,76,77)(H,87,88)/t31-,37+,39+,40+,41+,42+,43+,44+,45+,46-,49+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112120 (CHEMBL53181 | Cys-Phe-Trp-Lys-Tyr-Cys-Val) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CS)C(O)=O Show InChI InChI=1S/C46H61N9O9S2/c1-26(2)39(46(63)64)55-45(62)38(25-66)54-43(60)36(21-28-15-17-30(56)18-16-28)52-41(58)34(14-8-9-19-47)50-44(61)37(22-29-23-49-33-13-7-6-12-31(29)33)53-42(59)35(51-40(57)32(48)24-65)20-27-10-4-3-5-11-27/h3-7,10-13,15-18,23,26,32,34-39,49,56,65-66H,8-9,14,19-22,24-25,47-48H2,1-2H3,(H,50,61)(H,51,57)(H,52,58)(H,53,59)(H,54,60)(H,55,62)(H,63,64)/t32-,34-,35-,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112109 (Ala-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val | CHEM...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)C(C)N)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C62H85N13O16S2/c1-32(2)50(62(90)91)73-59(87)47(31-93)72-55(83)43(26-36-19-21-38(77)22-20-36)67-53(81)41(17-10-11-23-63)66-56(84)44(27-37-29-65-40-16-9-8-15-39(37)40)69-54(82)42(25-35-13-6-5-7-14-35)68-58(86)46(30-92)71-57(85)45(28-49(78)79)70-60(88)48-18-12-24-75(48)61(89)51(34(4)76)74-52(80)33(3)64/h5-9,13-16,19-22,29,32-34,41-48,50-51,65,76-77,92-93H,10-12,17-18,23-28,30-31,63-64H2,1-4H3,(H,66,84)(H,67,81)(H,68,86)(H,69,82)(H,70,88)(H,71,85)(H,72,83)(H,73,87)(H,74,80)(H,78,79)(H,90,91)/t33?,34-,41+,42+,43+,44+,45+,46+,47+,48-,50+,51+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50320463 (CHEMBL218994 | D[CFWKYC]V | H-Asp-Cys-Phe-Trp-Lys-...) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O Show InChI InChI=1S/C50H64N10O12S2/c1-27(2)42(50(71)72)60-49(70)40-26-74-73-25-39(58-43(64)33(52)23-41(62)63)48(69)56-36(20-28-10-4-3-5-11-28)45(66)57-38(22-30-24-53-34-13-7-6-12-32(30)34)47(68)54-35(14-8-9-19-51)44(65)55-37(46(67)59-40)21-29-15-17-31(61)18-16-29/h3-7,10-13,15-18,24,27,33,35-40,42,53,61H,8-9,14,19-23,25-26,51-52H2,1-2H3,(H,54,68)(H,55,65)(H,56,69)(H,57,66)(H,58,64)(H,59,67)(H,60,70)(H,62,63)(H,71,72)/t33-,35-,36-,37-,38-,39-,40-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112110 (CHEMBL436891 | Glu-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)C(C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C62H85N13O18S2/c1-31(2)50(62(92)93)74-60(90)47(30-95)73-56(86)43(25-35-17-19-37(77)20-18-35)69-54(84)41(16-10-11-23-63)67-57(87)44(26-36-28-65-40-15-9-8-14-38(36)40)71-55(85)42(24-34-12-6-5-7-13-34)70-59(89)46(29-94)72-58(88)45(27-49(80)81)68-52(82)32(3)66-61(91)51(33(4)76)75-53(83)39(64)21-22-48(78)79/h5-9,12-15,17-20,28,31-33,39,41-47,50-51,65,76-77,94-95H,10-11,16,21-27,29-30,63-64H2,1-4H3,(H,66,91)(H,67,87)(H,68,82)(H,69,84)(H,70,89)(H,71,85)(H,72,88)(H,73,86)(H,74,90)(H,75,83)(H,78,79)(H,80,81)(H,92,93)/t32?,33-,39+,41+,42+,43+,44+,45+,46+,47+,50+,51+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558697 (CHEMBL4780734) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CCC(N)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112111 (CHEMBL298803 | Cys-Phe-Trp-Lys-Tyr-Cys) Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(N)=O Show InChI InChI=1S/C41H53N9O7S2/c42-17-7-6-12-31(38(54)48-33(19-25-13-15-27(51)16-14-25)40(56)50-35(23-59)36(44)52)46-41(57)34(20-26-21-45-30-11-5-4-10-28(26)30)49-39(55)32(47-37(53)29(43)22-58)18-24-8-2-1-3-9-24/h1-5,8-11,13-16,21,29,31-35,45,51,58-59H,6-7,12,17-20,22-23,42-43H2,(H2,44,52)(H,46,57)(H,47,53)(H,48,54)(H,49,55)(H,50,56)/t29-,31-,32-,33-,34-,35-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.30	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112114 (CHEMBL427632 | Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](N)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C59H80N12O15S2/c1-31(2)49(59(85)86)70-56(82)45(30-88)69-52(78)41(25-34-18-20-36(73)21-19-34)64-50(76)39(16-9-10-22-60)63-53(79)42(26-35-28-62-38-15-8-7-14-37(35)38)66-51(77)40(24-33-12-5-4-6-13-33)65-55(81)44(29-87)68-54(80)43(27-47(74)75)67-57(83)46-17-11-23-71(46)58(84)48(61)32(3)72/h4-8,12-15,18-21,28,31-32,39-46,48-49,62,72-73,87-88H,9-11,16-17,22-27,29-30,60-61H2,1-3H3,(H,63,79)(H,64,76)(H,65,81)(H,66,77)(H,67,83)(H,68,80)(H,69,78)(H,70,82)(H,74,75)(H,85,86)/t32-,39+,40+,41+,42+,43+,44+,45+,46-,48+,49+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.40	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112123 (CHEMBL408106 | Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C64H87N13O18S2/c1-33(2)52(64(94)95)75-61(91)48(32-97)74-57(87)44(27-36-18-20-38(79)21-19-36)69-55(85)42(16-9-10-24-65)68-58(88)45(28-37-30-67-41-15-8-7-14-39(37)41)71-56(86)43(26-35-12-5-4-6-13-35)70-60(90)47(31-96)73-59(89)46(29-51(82)83)72-62(92)49-17-11-25-77(49)63(93)53(34(3)78)76-54(84)40(66)22-23-50(80)81/h4-8,12-15,18-21,30,33-34,40,42-49,52-53,67,78-79,96-97H,9-11,16-17,22-29,31-32,65-66H2,1-3H3,(H,68,88)(H,69,85)(H,70,90)(H,71,86)(H,72,92)(H,73,89)(H,74,87)(H,75,91)(H,76,84)(H,80,81)(H,82,83)(H,94,95)/t34-,40+,42+,43+,44+,45+,46+,47+,48+,49-,52+,53+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445383 (CHEMBL3104471) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H64N10O10S2/c1-27(2)41(49(68)69)59-48(67)40-26-71-70-25-39(57-42(61)28(3)51)47(66)55-36(21-29-11-5-4-6-12-29)44(63)56-38(23-31-24-52-34-14-8-7-13-33(31)34)46(65)53-35(15-9-10-20-50)43(62)54-37(45(64)58-40)22-30-16-18-32(60)19-17-30/h4-8,11-14,16-19,24,27-28,35-41,52,60H,9-10,15,20-23,25-26,50-51H2,1-3H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,61)(H,58,64)(H,59,67)(H,68,69)/t28-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112113 (CHEMBL410219 | Glu-Thr-Pro-Ala-Cys-Phe-Trp-Lys-Tyr...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)C(C)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C63H87N13O16S2/c1-33(2)51(63(91)92)74-60(88)48(32-94)73-57(85)45(28-37-19-21-39(78)22-20-37)69-55(83)43(17-10-11-25-64)68-58(86)46(29-38-30-66-42-16-9-8-15-40(38)42)71-56(84)44(27-36-13-6-5-7-14-36)70-59(87)47(31-93)72-53(81)34(3)67-61(89)49-18-12-26-76(49)62(90)52(35(4)77)75-54(82)41(65)23-24-50(79)80/h5-9,13-16,19-22,30,33-35,41,43-49,51-52,66,77-78,93-94H,10-12,17-18,23-29,31-32,64-65H2,1-4H3,(H,67,89)(H,68,86)(H,69,83)(H,70,87)(H,71,84)(H,72,81)(H,73,85)(H,74,88)(H,75,82)(H,79,80)(H,91,92)/t34?,35-,41+,43+,44+,45+,46+,47+,48+,49-,51+,52+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50517323 (CHEMBL4474481) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1C)C(O)=O |r| Show InChI InChI=1S/C65H87N13O18S2/c1-34(2)53(65(95)96)75-62(92)50-33-98-97-32-48(74-59(89)46(30-52(83)84)72-61(91)49-18-12-26-78(49)64(94)54(35(3)79)76-55(85)41(67)23-24-51(81)82)60(90)70-44(27-36-13-6-5-7-14-36)57(87)71-45(29-38-31-68-42-16-9-8-15-40(38)42)58(88)69-43(17-10-11-25-66)56(86)73-47(63(93)77(50)4)28-37-19-21-39(80)22-20-37/h5-9,13-16,19-22,31,34-35,41,43-50,53-54,68,79-80H,10-12,17-18,23-30,32-33,66-67H2,1-4H3,(H,69,88)(H,70,90)(H,71,87)(H,72,91)(H,73,86)(H,74,89)(H,75,92)(H,76,85)(H,81,82)(H,83,84)(H,95,96)/t35-,41+,43+,44+,45+,46+,47+,48+,49+,50+,53+,54+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112116 (Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val | CHEMBL414256) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@@H](N)CC(O)=O)C(O)=O Show InChI InChI=1S/C50H66N10O12S2/c1-27(2)42(50(71)72)60-49(70)40(26-74)59-46(67)37(21-29-15-17-31(61)18-16-29)55-44(65)35(14-8-9-19-51)54-47(68)38(22-30-24-53-34-13-7-6-12-32(30)34)57-45(66)36(20-28-10-4-3-5-11-28)56-48(69)39(25-73)58-43(64)33(52)23-41(62)63/h3-7,10-13,15-18,24,27,33,35-40,42,53,61,73-74H,8-9,14,19-23,25-26,51-52H2,1-2H3,(H,54,68)(H,55,65)(H,56,69)(H,57,66)(H,58,64)(H,59,67)(H,60,70)(H,62,63)(H,71,72)/t33-,35-,36-,37-,38-,39-,40-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50517314 (Urotensin-II) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C64H85N13O18S2/c1-33(2)52(64(94)95)75-61(91)48-32-97-96-31-47(73-59(89)46(29-51(82)83)72-62(92)49-17-11-25-77(49)63(93)53(34(3)78)76-54(84)40(66)22-23-50(80)81)60(90)70-43(26-35-12-5-4-6-13-35)56(86)71-45(28-37-30-67-41-15-8-7-14-39(37)41)58(88)68-42(16-9-10-24-65)55(85)69-44(57(87)74-48)27-36-18-20-38(79)21-19-36/h4-8,12-15,18-21,30,33-34,40,42-49,52-53,67,78-79H,9-11,16-17,22-29,31-32,65-66H2,1-3H3,(H,68,88)(H,69,85)(H,70,90)(H,71,86)(H,72,92)(H,73,89)(H,74,87)(H,75,91)(H,76,84)(H,80,81)(H,82,83)(H,94,95)/t34-,40+,42+,43+,44+,45+,46+,47+,48+,49+,52+,53+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112105 (CHEMBL437036 | Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr...) Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](N)CCC(O)=O)C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)NC(C)C(O)=O Show InChI InChI=1S/C62H83N13O18S2/c1-32(62(92)93)66-58(88)46(30-94)72-55(85)43(26-35-17-19-37(77)20-18-35)68-53(83)41(15-8-9-23-63)67-56(86)44(27-36-29-65-40-14-7-6-13-38(36)40)70-54(84)42(25-34-11-4-3-5-12-34)69-59(89)47(31-95)73-57(87)45(28-50(80)81)71-60(90)48-16-10-24-75(48)61(91)51(33(2)76)74-52(82)39(64)21-22-49(78)79/h3-7,11-14,17-20,29,32-33,39,41-48,51,65,76-77,94-95H,8-10,15-16,21-28,30-31,63-64H2,1-2H3,(H,66,88)(H,67,86)(H,68,83)(H,69,89)(H,70,84)(H,71,90)(H,72,85)(H,73,87)(H,74,82)(H,78,79)(H,80,81)(H,92,93)/t32?,33-,39+,41+,42+,43+,44+,45+,46+,47+,48-,51+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112121 (CHEMBL412042 | Glu-Ala-Pro-Asp-Cys-Phe-Trp-Lys-Tyr...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)C(C)NC(=O)[C@@H](N)CCC(O)=O)C(O)=O Show InChI InChI=1S/C63H85N13O17S2/c1-33(2)52(63(92)93)75-60(89)48(32-95)74-56(85)44(27-36-18-20-38(77)21-19-36)69-54(83)42(16-9-10-24-64)68-57(86)45(28-37-30-66-41-15-8-7-14-39(37)41)71-55(84)43(26-35-12-5-4-6-13-35)70-59(88)47(31-94)73-58(87)46(29-51(80)81)72-61(90)49-17-11-25-76(49)62(91)34(3)67-53(82)40(65)22-23-50(78)79/h4-8,12-15,18-21,30,33-34,40,42-49,52,66,77,94-95H,9-11,16-17,22-29,31-32,64-65H2,1-3H3,(H,67,82)(H,68,86)(H,69,83)(H,70,88)(H,71,84)(H,72,90)(H,73,87)(H,74,85)(H,75,89)(H,78,79)(H,80,81)(H,92,93)/t34?,40-,42-,43-,44-,45-,46-,47-,48-,49+,52-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558675 (CHEMBL4757669) Show SMILES CCC(NC(=O)[C@H](Cc1ccc(O)c(c1)[N+]([O-])=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CC(N)=O)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50413782 (CHEMBL1627325) Show SMILES [#6]-[#16]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#8])C([#6])([#6])[#6])-[#6](-[#6])-[#6])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](-[#8])=O Show InChI InChI=1S/C97H163N31O28S/c1-50(2)73(126-93(154)76(97(6,7)8)128-88(149)66(44-70(103)135)122-81(142)61(32-23-40-109-96(106)107)118-86(147)64(120-78(139)56(101)47-129)42-54-24-12-10-13-25-54)90(151)110-46-72(137)125-74(52(4)132)91(152)111-45-71(136)113-63(35-41-157-9)84(145)115-58(29-17-20-37-99)80(141)116-59(30-18-21-38-100)85(146)127-75(53(5)133)92(153)123-67(48-130)89(150)121-65(43-55-26-14-11-15-27-55)87(148)119-62(33-34-69(102)134)83(144)117-60(31-22-39-108-95(104)105)79(140)112-51(3)77(138)114-57(28-16-19-36-98)82(143)124-68(49-131)94(155)156/h10-15,24-27,50-53,56-68,73-76,129-133H,16-23,28-49,98-101H2,1-9H3,(H2,102,134)(H2,103,135)(H,110,151)(H,111,152)(H,112,140)(H,113,136)(H,114,138)(H,115,145)(H,116,141)(H,117,144)(H,118,147)(H,119,148)(H,120,139)(H,121,150)(H,122,142)(H,123,153)(H,124,143)(H,125,137)(H,126,154)(H,127,146)(H,128,149)(H,155,156)(H4,104,105,108)(H4,106,107,109)/t51-,52+,53+,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,73-,74-,75-,76-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
National Institute of Neuroscienc Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in CHO cells assessed as inhibition of urotensin 2-induced intracellular calc...				J Med Chem 52: 4068-71 (2009) Article DOI: 10.1021/jm900604g BindingDB Entry DOI: 10.7270/Q2445NQD
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112103 (CHEMBL216349 | Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1)C(O)=O Show InChI InChI=1S/C55H73N11O13S2/c1-30(2)46(55(78)79)66-54(77)44(29-81)65-50(73)40(24-32-17-19-34(67)20-18-32)60-48(71)38(15-8-9-21-56)59-51(74)41(25-33-27-58-36-14-7-6-13-35(33)36)62-49(72)39(23-31-11-4-3-5-12-31)61-53(76)43(28-80)64-52(75)42(26-45(68)69)63-47(70)37-16-10-22-57-37/h3-7,11-14,17-20,27,30,37-44,46,57-58,67,80-81H,8-10,15-16,21-26,28-29,56H2,1-2H3,(H,59,74)(H,60,71)(H,61,76)(H,62,72)(H,63,70)(H,64,75)(H,65,73)(H,66,77)(H,68,69)(H,78,79)/t37-,38+,39+,40+,41+,42+,43+,44+,46+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50517320 (CHEMBL4568153) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C51H66N10O12S2/c1-28(2)43(51(72)73)60-48(69)40-27-75-74-26-39(58-44(65)34(53)24-42(63)64)47(68)57-38(22-29-11-5-4-6-12-29)50(71)61(3)41(23-31-25-54-35-14-8-7-13-33(31)35)49(70)55-36(15-9-10-20-52)45(66)56-37(46(67)59-40)21-30-16-18-32(62)19-17-30/h4-8,11-14,16-19,25,28,34,36-41,43,54,62H,9-10,15,20-24,26-27,52-53H2,1-3H3,(H,55,70)(H,56,66)(H,57,68)(H,58,65)(H,59,67)(H,60,69)(H,63,64)(H,72,73)/t34-,36-,37-,38-,39-,40-,41-,43-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445383 (CHEMBL3104471) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H64N10O10S2/c1-27(2)41(49(68)69)59-48(67)40-26-71-70-25-39(57-42(61)28(3)51)47(66)55-36(21-29-11-5-4-6-12-29)44(63)56-38(23-31-24-52-34-14-8-7-13-33(31)34)46(65)53-35(15-9-10-20-50)43(62)54-37(45(64)58-40)22-30-16-18-32(60)19-17-30/h4-8,11-14,16-19,24,27-28,35-41,52,60H,9-10,15,20-23,25-26,50-51H2,1-3H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,61)(H,58,64)(H,59,67)(H,68,69)/t28-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Agonist activity at human UT receptor expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as induction of Gq activation ...				J Med Chem 61: 8707-8716 (2018) Article DOI: 10.1021/acs.jmedchem.8b00789 BindingDB Entry DOI: 10.7270/Q2959M57
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112118 (CHEMBL385962 | Glu-Thr-Pro-Asp-Cys-Phe-D-Trp-Lys-T...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C64H87N13O18S2/c1-33(2)52(64(94)95)75-61(91)48(32-97)74-57(87)44(27-36-18-20-38(79)21-19-36)69-55(85)42(16-9-10-24-65)68-58(88)45(28-37-30-67-41-15-8-7-14-39(37)41)71-56(86)43(26-35-12-5-4-6-13-35)70-60(90)47(31-96)73-59(89)46(29-51(82)83)72-62(92)49-17-11-25-77(49)63(93)53(34(3)78)76-54(84)40(66)22-23-50(80)81/h4-8,12-15,18-21,30,33-34,40,42-49,52-53,67,78-79,96-97H,9-11,16-17,22-29,31-32,65-66H2,1-3H3,(H,68,88)(H,69,85)(H,70,90)(H,71,86)(H,72,92)(H,73,89)(H,74,87)(H,75,91)(H,76,84)(H,80,81)(H,82,83)(H,94,95)/t34-,40+,42+,43+,44+,45-,46+,47+,48+,49-,52+,53+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558681 (CHEMBL4746051) Show SMILES NCCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558698 (CHEMBL4745061) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	3.90	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50413784 (UROTENSIN-II) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C64H85N13O18S2/c1-33(2)52(64(94)95)75-61(91)48-32-97-96-31-47(73-59(89)46(29-51(82)83)72-62(92)49-17-11-25-77(49)63(93)53(34(3)78)76-54(84)40(66)22-23-50(80)81)60(90)70-43(26-35-12-5-4-6-13-35)56(86)71-45(28-37-30-67-41-15-8-7-14-39(37)41)58(88)68-42(16-9-10-24-65)55(85)69-44(57(87)74-48)27-36-18-20-38(79)21-19-36/h4-8,12-15,18-21,30,33-34,40,42-49,52-53,67,78-79H,9-11,16-17,22-29,31-32,65-66H2,1-3H3,(H,68,88)(H,69,85)(H,70,90)(H,71,86)(H,72,92)(H,73,89)(H,74,87)(H,75,91)(H,76,84)(H,80,81)(H,82,83)(H,94,95)/t34-,40+,42+,43+,44+,45+,46+,47+,48+,49-,52+,53+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
National Institute of Neuroscienc Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in CHO cells assessed as inhibition of urotensin 2-induced intracellular calc...				J Med Chem 52: 4068-71 (2009) Article DOI: 10.1021/jm900604g BindingDB Entry DOI: 10.7270/Q2445NQD
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50269950 (CHEMBL4100932) Show SMILES Cl.NCCCCN1N=C(\C=C\c2ccc(O)cc2)c2ccccc2N(Cc2ccc(cc2)-c2ccccc2)C1=O |t:6| Show InChI InChI=1S/C33H32N4O2/c34-22-6-7-23-37-33(39)36(24-26-12-17-28(18-13-26)27-8-2-1-3-9-27)32-11-5-4-10-30(32)31(35-37)21-16-25-14-19-29(38)20-15-25/h1-5,8-21,38H,6-7,22-24,34H2/b21-16+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.20	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in URP-induced Gq activation by measuring URP pEC50 ...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50517315 (CHEMBL4454498) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1C)C(O)=O |r| Show InChI InChI=1S/C51H66N10O12S2/c1-28(2)43(51(72)73)60-49(70)41-27-75-74-26-40(59-44(65)34(53)24-42(63)64)48(69)56-37(21-29-11-5-4-6-12-29)46(67)57-38(23-31-25-54-35-14-8-7-13-33(31)35)47(68)55-36(15-9-10-20-52)45(66)58-39(50(71)61(41)3)22-30-16-18-32(62)19-17-30/h4-8,11-14,16-19,25,28,34,36-41,43,54,62H,9-10,15,20-24,26-27,52-53H2,1-3H3,(H,55,68)(H,56,69)(H,57,67)(H,58,66)(H,59,65)(H,60,70)(H,63,64)(H,72,73)/t34-,36-,37-,38-,39-,40-,41-,43-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.70	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558706 (CHEMBL4750625) Show SMILES CCC(NC(=O)[C@H](Cc1ccc(O)c(c1)[N+]([O-])=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](N)CC(N)=O)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558699 (CHEMBL4743591) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50269955 (CHEMBL4066696) Show SMILES Cl.NCCCCN1N=C(CCc2ccc(O)cc2)c2ccccc2N(Cc2ccc3ccccc3c2)C1=O |t:6| Show InChI InChI=1S/C31H32N4O2/c32-19-5-6-20-35-31(37)34(22-24-11-15-25-7-1-2-8-26(25)21-24)30-10-4-3-9-28(30)29(33-35)18-14-23-12-16-27(36)17-13-23/h1-4,7-13,15-17,21,36H,5-6,14,18-20,22,32H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in URP-induced Gq activation by measuring URP pEC50 ...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50517316 (CHEMBL4462940) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1C)C(O)=O |r| Show InChI InChI=1S/C50H66N10O10S2/c1-28(2)42(50(69)70)59-48(67)41-27-72-71-26-40(58-43(62)29(3)52)47(66)55-37(22-30-12-6-5-7-13-30)45(64)56-38(24-32-25-53-35-15-9-8-14-34(32)35)46(65)54-36(16-10-11-21-51)44(63)57-39(49(68)60(41)4)23-31-17-19-33(61)20-18-31/h5-9,12-15,17-20,25,28-29,36-42,53,61H,10-11,16,21-24,26-27,51-52H2,1-4H3,(H,54,65)(H,55,66)(H,56,64)(H,57,63)(H,58,62)(H,59,67)(H,69,70)/t29-,36-,37-,38-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50517317 (CHEMBL4475783) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N(C)[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C65H87N13O18S2/c1-34(2)53(65(95)96)75-60(90)48-33-98-97-32-47(73-58(88)45(30-52(83)84)71-61(91)49-18-12-26-78(49)64(94)54(35(3)79)76-55(85)41(67)23-24-51(81)82)59(89)72-46(28-36-13-6-5-7-14-36)63(93)77(4)50(29-38-31-68-42-16-9-8-15-40(38)42)62(92)69-43(17-10-11-25-66)56(86)70-44(57(87)74-48)27-37-19-21-39(80)22-20-37/h5-9,13-16,19-22,31,34-35,41,43-50,53-54,68,79-80H,10-12,17-18,23-30,32-33,66-67H2,1-4H3,(H,69,92)(H,70,86)(H,71,91)(H,72,89)(H,73,88)(H,74,87)(H,75,90)(H,76,85)(H,81,82)(H,83,84)(H,95,96)/t35-,41+,43+,44+,45+,46+,47+,48+,49+,50+,53+,54+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.60	n/a	n/a	n/a	n/a
University of Naples "Federico II" Curated by ChEMBL					Assay Description Agonist activity at urotensin 2 receptor (unknown origin) expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as inducti...				J Med Chem 62: 1455-1467 (2019) Article DOI: 10.1021/acs.jmedchem.8b01601 BindingDB Entry DOI: 10.7270/Q2PV6PRV
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50112122 (CHEMBL405324 | Glu-Thr-Pro-Asp-Cys-Ala-Trp-Lys-Tyr...) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(C)NC(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(O)=O Show InChI InChI=1S/C58H83N13O18S2/c1-28(2)46(58(88)89)69-55(85)42(27-91)68-51(81)38(22-31-14-16-33(73)17-15-31)65-50(80)37(12-7-8-20-59)63-52(82)39(23-32-25-61-36-11-6-5-10-34(32)36)64-48(78)29(3)62-54(84)41(26-90)67-53(83)40(24-45(76)77)66-56(86)43-13-9-21-71(43)57(87)47(30(4)72)70-49(79)35(60)18-19-44(74)75/h5-6,10-11,14-17,25,28-30,35,37-43,46-47,61,72-73,90-91H,7-9,12-13,18-24,26-27,59-60H2,1-4H3,(H,62,84)(H,63,82)(H,64,78)(H,65,80)(H,66,86)(H,67,83)(H,68,81)(H,69,85)(H,70,79)(H,74,75)(H,76,77)(H,88,89)/t29?,30-,35+,37+,38+,39+,40+,41+,42+,43-,46+,47+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
Aventis Pharma Germany GmbH Curated by ChEMBL					Assay Description Mobilization of intracellular calcium in CHO cells transiently transfected with human Urotensin 2 receptor				J Med Chem 45: 1799-805 (2002) BindingDB Entry DOI: 10.7270/Q23N22Q3
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50269960 (CHEMBL4076150) Show SMILES Cl.NCCCN1N=C(CCc2nc3ccccc3s2)c2ccccc2N(Cc2ccc3ccccc3c2)C1=O |t:5| Show InChI InChI=1S/C31H29N5OS/c32-18-7-19-36-31(37)35(21-22-14-15-23-8-1-2-9-24(23)20-22)28-12-5-3-10-25(28)26(34-36)16-17-30-33-27-11-4-6-13-29(27)38-30/h1-6,8-15,20H,7,16-19,21,32H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in URP-induced Gq activation by measuring URP pEC50 ...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50304252 ((6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-...) Show SMILES NCCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O |r| Show InChI InChI=1S/C42H50N8O7/c43-19-7-6-13-32-38(53)49-35(22-27-15-17-29(51)18-16-27)42(57)50-20-8-14-36(50)41(56)45-25-37(52)46-33(21-26-9-2-1-3-10-26)39(54)48-34(40(55)47-32)23-28-24-44-31-12-5-4-11-30(28)31/h1-5,9-12,15-18,24,32-36,44,51H,6-8,13-14,19-23,25,43H2,(H,45,56)(H,46,52)(H,47,55)(H,48,54)(H,49,53)/t32-,33-,34-,35-,36-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.94	n/a	n/a	n/a	n/a
PRISM Bio. Lab. Corporation Curated by ChEMBL					Assay Description Agonist activity at human GPR14 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem 17: 6742-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.058 BindingDB Entry DOI: 10.7270/Q2F47Q28
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50459265 (CHEMBL4205274) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccc(I)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C50H63IN10O12S2/c1-26(2)42(50(72)73)61-49(71)40-25-75-74-24-39(59-43(65)33(53)22-41(63)64)48(70)57-36(19-27-10-14-30(51)15-11-27)45(67)58-38(21-29-23-54-34-8-4-3-7-32(29)34)47(69)55-35(9-5-6-18-52)44(66)56-37(46(68)60-40)20-28-12-16-31(62)17-13-28/h3-4,7-8,10-17,23,26,33,35-40,42,54,62H,5-6,9,18-22,24-25,52-53H2,1-2H3,(H,55,69)(H,56,66)(H,57,70)(H,58,67)(H,59,65)(H,60,68)(H,61,71)(H,63,64)(H,72,73)/t33-,35-,36-,37-,38-,39-,40-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7.10	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Agonist activity at human UT receptor expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as induction of Gq activation ...				J Med Chem 61: 8707-8716 (2018) Article DOI: 10.1021/acs.jmedchem.8b00789 BindingDB Entry DOI: 10.7270/Q2959M57
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50269946 (CHEMBL4071437) Show SMILES Cl.COc1ccc(\C=C\C2=NN(CCCCN)C(=O)N(Cc3ccc(cc3)-c3ccccc3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C34H34N4O2/c1-40-30-20-15-26(16-21-30)17-22-32-31-11-5-6-12-33(31)37(34(39)38(36-32)24-8-7-23-35)25-27-13-18-29(19-14-27)28-9-3-2-4-10-28/h2-6,9-22H,7-8,23-25,35H2,1H3/b22-17+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.10	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in URP-induced Gq activation by measuring URP pEC50 ...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558676 (CHEMBL4757895) Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)C(Cc1ccc2ccccc2c1)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)c(c1)[N+]([O-])=O)C(=O)N[C@@H](CS)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	8.10	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50269946 (CHEMBL4071437) Show SMILES Cl.COc1ccc(\C=C\C2=NN(CCCCN)C(=O)N(Cc3ccc(cc3)-c3ccccc3)c3ccccc23)cc1 |t:8| Show InChI InChI=1S/C34H34N4O2/c1-40-30-20-15-26(16-21-30)17-22-32-31-11-5-6-12-33(31)37(34(39)38(36-32)24-8-7-23-35)25-27-13-18-29(19-14-27)28-9-3-2-4-10-28/h2-6,9-22H,7-8,23-25,35H2,1H3/b22-17+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in human urotensin-2-induced Gq activation by measur...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50304253 ((6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-...) Show SMILES NCCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O |r| Show InChI InChI=1S/C36H46N8O8/c37-14-4-3-8-26-32(48)43-28(16-21-10-12-23(46)13-11-21)36(52)44-15-5-9-30(44)35(51)39-19-31(47)40-29(20-45)34(50)42-27(33(49)41-26)17-22-18-38-25-7-2-1-6-24(22)25/h1-2,6-7,10-13,18,26-30,38,45-46H,3-5,8-9,14-17,19-20,37H2,(H,39,51)(H,40,47)(H,41,49)(H,42,50)(H,43,48)/t26-,27-,28-,29-,30-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.51	n/a	n/a	n/a	n/a
PRISM Bio. Lab. Corporation Curated by ChEMBL					Assay Description Agonist activity at human GPR14 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem 17: 6742-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.058 BindingDB Entry DOI: 10.7270/Q2F47Q28
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558688 (CHEMBL4789420) Show SMILES CC(C)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(N)=O)C(C)C)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	9.60	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558692 (CHEMBL4745321) Show SMILES NCCCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558701 (CHEMBL4740325) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CS)C(N)=O)cc1 |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human U-IIR expressed in HEK293-A cells by Fluo4-AM dye based intracellular calcium mobilization assay				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50304256 ((6S,9S,12S,15S,20aS)-9-((1H-indol-3-yl)methyl)-12-...) Show SMILES NCCCC[C@@H]1NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C36H46N8O7/c37-15-7-6-13-26-32(47)43-28(17-22-9-2-1-3-10-22)36(51)44-16-8-14-30(44)35(50)39-20-31(46)40-29(21-45)34(49)42-27(33(48)41-26)18-23-19-38-25-12-5-4-11-24(23)25/h1-5,9-12,19,26-30,38,45H,6-8,13-18,20-21,37H2,(H,39,50)(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t26-,27-,28-,29-,30-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10.1	n/a	n/a	n/a	n/a
PRISM Bio. Lab. Corporation Curated by ChEMBL					Assay Description Agonist activity at human GPR14 expressed in HEK293 cells by calcium mobilization assay				Bioorg Med Chem 17: 6742-7 (2009) Article DOI: 10.1016/j.bmc.2009.07.058 BindingDB Entry DOI: 10.7270/Q2F47Q28
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50269955 (CHEMBL4066696) Show SMILES Cl.NCCCCN1N=C(CCc2ccc(O)cc2)c2ccccc2N(Cc2ccc3ccccc3c2)C1=O |t:6| Show InChI InChI=1S/C31H32N4O2/c32-19-5-6-20-35-31(37)34(22-24-11-15-25-7-1-2-8-26(25)21-24)30-10-4-3-9-28(30)29(33-35)18-14-23-12-16-27(36)17-13-23/h1-4,7-13,15-17,21,36H,5-6,14,18-20,22,32H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Allosteric modulation of human urotensin-2 receptor expressed in HEK293 cells assessed as change in human urotensin-2-induced Gq activation by measur...				J Med Chem 60: 9838-9859 (2017) Article DOI: 10.1021/acs.jmedchem.7b01525 BindingDB Entry DOI: 10.7270/Q2V1279D
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50459266 (CHEMBL4217514) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccc(I)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H63IN10O10S2/c1-26(2)41(49(69)70)60-48(68)40-25-72-71-24-39(58-42(62)27(3)52)47(67)56-36(20-28-11-15-31(50)16-12-28)44(64)57-38(22-30-23-53-34-9-5-4-8-33(30)34)46(66)54-35(10-6-7-19-51)43(63)55-37(45(65)59-40)21-29-13-17-32(61)18-14-29/h4-5,8-9,11-18,23,26-27,35-41,53,61H,6-7,10,19-22,24-25,51-52H2,1-3H3,(H,54,66)(H,55,63)(H,56,67)(H,57,64)(H,58,62)(H,59,65)(H,60,68)(H,69,70)/t27-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Agonist activity at human UT receptor expressed in HEK293 cells co-expressing Gq-polycistronic BRET biosensor assessed as induction of Gq activation ...				J Med Chem 61: 8707-8716 (2018) Article DOI: 10.1021/acs.jmedchem.8b00789 BindingDB Entry DOI: 10.7270/Q2959M57
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 218 total )  |  Next  |  Last  >>

Jump to: