Compile Data Set for Download or QSAR

Found 342 hits of ic50 data for polymerid = 49001069,49001070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445384 (CHEMBL3104469) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCc3ccccc3[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C50H67N9O10S2/c1-28(2)39(49(68)69)57-45(64)38-27-70-71-50(4,5)41(58-42(61)29(3)52)47(66)55-37(26-30-13-7-6-8-14-30)48(67)59-24-22-32-15-9-10-16-34(32)40(59)46(65)53-35(17-11-12-23-51)43(62)54-36(44(63)56-38)25-31-18-20-33(60)21-19-31/h6-10,13-16,18-21,28-29,35-41,60H,11-12,17,22-27,51-52H2,1-5H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,64)(H,58,61)(H,68,69)/t29-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445385 (CHEMBL3104468) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2Cc3[nH]c4ccccc4c3C[C@H]2C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H62N10O10S2/c1-26(2)41(49(68)69)58-46(65)39-25-71-70-24-38(56-42(61)27(3)51)45(64)55-36(21-28-10-5-4-6-11-28)48(67)59-23-37-32(31-12-7-8-13-33(31)52-37)22-40(59)47(66)53-34(14-9-19-50)43(62)54-35(44(63)57-39)20-29-15-17-30(60)18-16-29/h4-8,10-13,15-18,26-27,34-36,38-41,52,60H,9,14,19-25,50-51H2,1-3H3,(H,53,66)(H,54,62)(H,55,64)(H,56,61)(H,57,63)(H,58,65)(H,68,69)/t27-,34-,35-,36-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445368 (CHEMBL3104466) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2Cc3ccccc3C[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C48H63N9O10S2/c1-27(2)40(48(66)67)56-45(63)38-26-69-68-25-37(54-41(59)28(3)50)44(62)53-36(22-29-11-5-4-6-12-29)47(65)57-24-32-14-8-7-13-31(32)23-39(57)46(64)51-34(15-9-10-20-49)42(60)52-35(43(61)55-38)21-30-16-18-33(58)19-17-30/h4-8,11-14,16-19,27-28,34-40,58H,9-10,15,20-26,49-50H2,1-3H3,(H,51,64)(H,52,60)(H,53,62)(H,54,59)(H,55,61)(H,56,63)(H,66,67)/t28-,34-,35-,36-,37-,38-,39-,40-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445378 (CHEMBL3104642) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C44H65N9O10S2/c1-24(2)34(43(62)63)52-41(60)33-23-65-64-22-32(50-36(55)25(3)46)40(59)49-31(20-26-12-8-7-9-13-26)39(58)53-35(44(4,5)6)42(61)47-29(14-10-11-19-45)37(56)48-30(38(57)51-33)21-27-15-17-28(54)18-16-27/h7-9,12-13,15-18,24-25,29-35,54H,10-11,14,19-23,45-46H2,1-6H3,(H,47,61)(H,48,56)(H,49,59)(H,50,55)(H,51,57)(H,52,60)(H,53,58)(H,62,63)/t25-,29-,30-,31-,32-,33-,34-,35-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445386 (CHEMBL3104641) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C44H65N9O10S2/c1-24(2)34(43(62)63)52-41(60)33-23-65-64-22-32(50-36(55)25(3)46)40(59)49-31(20-26-12-8-7-9-13-26)39(58)53-35(44(4,5)6)42(61)47-29(14-10-11-19-45)37(56)48-30(38(57)51-33)21-27-15-17-28(54)18-16-27/h7-9,12-13,15-18,24-25,29-35,54H,10-11,14,19-23,45-46H2,1-6H3,(H,47,61)(H,48,56)(H,49,59)(H,50,55)(H,51,57)(H,52,60)(H,53,58)(H,62,63)/t25-,29-,30-,31-,32-,33-,34-,35+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445384 (CHEMBL3104469) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC(C)(C)[C@@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCc3ccccc3[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C50H67N9O10S2/c1-28(2)39(49(68)69)57-45(64)38-27-70-71-50(4,5)41(58-42(61)29(3)52)47(66)55-37(26-30-13-7-6-8-14-30)48(67)59-24-22-32-15-9-10-16-34(32)40(59)46(65)53-35(17-11-12-23-51)43(62)54-36(44(63)56-38)25-31-18-20-33(60)21-19-31/h6-10,13-16,18-21,28-29,35-41,60H,11-12,17,22-27,51-52H2,1-5H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,64)(H,58,61)(H,68,69)/t29-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445385 (CHEMBL3104468) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2Cc3[nH]c4ccccc4c3C[C@H]2C(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H62N10O10S2/c1-26(2)41(49(68)69)58-46(65)39-25-71-70-24-38(56-42(61)27(3)51)45(64)55-36(21-28-10-5-4-6-11-28)48(67)59-23-37-32(31-12-7-8-13-33(31)52-37)22-40(59)47(66)53-34(14-9-19-50)43(62)54-35(44(63)57-39)20-29-15-17-30(60)18-16-29/h4-8,10-13,15-18,26-27,34-36,38-41,52,60H,9,14,19-25,50-51H2,1-3H3,(H,53,66)(H,54,62)(H,55,64)(H,56,61)(H,57,63)(H,58,65)(H,68,69)/t27-,34-,35-,36-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445368 (CHEMBL3104466) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2Cc3ccccc3C[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C48H63N9O10S2/c1-27(2)40(48(66)67)56-45(63)38-26-69-68-25-37(54-41(59)28(3)50)44(62)53-36(22-29-11-5-4-6-12-29)47(65)57-24-32-14-8-7-13-31(32)23-39(57)46(64)51-34(15-9-10-20-49)42(60)52-35(43(61)55-38)21-30-16-18-33(58)19-17-30/h4-8,11-14,16-19,27-28,34-40,58H,9-10,15,20-26,49-50H2,1-3H3,(H,51,64)(H,52,60)(H,53,62)(H,54,59)(H,55,61)(H,56,63)(H,66,67)/t28-,34-,35-,36-,37-,38-,39-,40-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445378 (CHEMBL3104642) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C44H65N9O10S2/c1-24(2)34(43(62)63)52-41(60)33-23-65-64-22-32(50-36(55)25(3)46)40(59)49-31(20-26-12-8-7-9-13-26)39(58)53-35(44(4,5)6)42(61)47-29(14-10-11-19-45)37(56)48-30(38(57)51-33)21-27-15-17-28(54)18-16-27/h7-9,12-13,15-18,24-25,29-35,54H,10-11,14,19-23,45-46H2,1-6H3,(H,47,61)(H,48,56)(H,49,59)(H,50,55)(H,51,57)(H,52,60)(H,53,58)(H,62,63)/t25-,29-,30-,31-,32-,33-,34-,35-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445386 (CHEMBL3104641) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C44H65N9O10S2/c1-24(2)34(43(62)63)52-41(60)33-23-65-64-22-32(50-36(55)25(3)46)40(59)49-31(20-26-12-8-7-9-13-26)39(58)53-35(44(4,5)6)42(61)47-29(14-10-11-19-45)37(56)48-30(38(57)51-33)21-27-15-17-28(54)18-16-27/h7-9,12-13,15-18,24-25,29-35,54H,10-11,14,19-23,45-46H2,1-6H3,(H,47,61)(H,48,56)(H,49,59)(H,50,55)(H,51,57)(H,52,60)(H,53,58)(H,62,63)/t25-,29-,30-,31-,32-,33-,34-,35+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>0	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558696 (CHEMBL4777970) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I-Tyr9]-U-II from human U-IIR expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand b...				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302270 ((R)-2-(4-(6-chloropyrazin-2-ylamino)-1-(3,4-dimeth...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNc1cncc(Cl)n1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C30H37ClN6O3/c1-4-35-13-15-36(16-14-35)25-8-5-7-22-23(25)20-37(30(22)38)24(21-10-11-26(39-2)27(17-21)40-3)9-6-12-33-29-19-32-18-28(31)34-29/h5,7-8,10-11,17-19,24H,4,6,9,12-16,20H2,1-3H3,(H,33,34)/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302257 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNS(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C30H38N4O5S2/c1-4-32-15-17-33(18-16-32)26-9-5-8-23-24(26)21-34(30(23)35)25(22-12-13-27(38-2)28(20-22)39-3)10-6-14-31-41(36,37)29-11-7-19-40-29/h5,7-9,11-13,19-20,25,31H,4,6,10,14-18,21H2,1-3H3/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302264 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-isopropylpi...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCN(C)S(=O)(=O)c1cccs1)N1Cc2c(cccc2N2CCN(CC2)C(C)C)C1=O |r| Show InChI InChI=1S/C32H42N4O5S2/c1-23(2)34-16-18-35(19-17-34)28-10-6-9-25-26(28)22-36(32(25)37)27(24-13-14-29(40-4)30(21-24)41-5)11-7-15-33(3)43(38,39)31-12-8-20-42-31/h6,8-10,12-14,20-21,23,27H,7,11,15-19,22H2,1-5H3/t27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50558695 (CHEMBL4741230) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [125I-Tyr9]-U-II from human U-IIR expressed in HEK293-A cells incubated for 30 mins by gamma counting based competition radioligand b...				Citation and Details BindingDB Entry DOI: 10.7270/Q2377DCH
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50543457 (CHEMBL4635039) Show SMILES [H][C@]1(CSSC[C@]([H])(NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2ccc(I)cc2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C47H62IN9O10S2/c1-26(2)39(47(66)67)57-46(65)38-25-69-68-24-37(55-40(59)27(3)50)45(64)54-34(21-28-9-5-4-6-10-28)43(62)53-35(22-29-12-16-31(48)17-13-29)42(61)51-33(11-7-8-20-49)41(60)52-36(44(63)56-38)23-30-14-18-32(58)19-15-30/h4-6,9-10,12-19,26-27,33-39,58H,7-8,11,20-25,49-50H2,1-3H3,(H,51,61)(H,52,60)(H,53,62)(H,54,64)(H,55,59)(H,56,63)(H,57,65)(H,66,67)/t27-,33-,34-,35+,36-,37-,38-,39-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Antagonist activity at human UT receptor expressed in HEK293 cells using Na [125I] incubated for 2 hrs by gamma counting method				ACS Med Chem Lett 11: 1717-1722 (2020) Article DOI: 10.1021/acsmedchemlett.0c00223 BindingDB Entry DOI: 10.7270/Q269775C
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302258 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-isopropylpi...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCNS(=O)(=O)c1cccs1)N1Cc2c(cccc2N2CCN(CC2)C(C)C)C1=O |r| Show InChI InChI=1S/C31H40N4O5S2/c1-22(2)33-15-17-34(18-16-33)27-9-5-8-24-25(27)21-35(31(24)36)26(23-12-13-28(39-3)29(20-23)40-4)10-6-14-32-42(37,38)30-11-7-19-41-30/h5,7-9,11-13,19-20,22,26,32H,6,10,14-18,21H2,1-4H3/t26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50543458 (CHEMBL4642307) Show SMILES [H][C@]1(CSSC[C@]([H])(NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2ccc(cc2)-c2ccccc2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C53H67N9O10S2/c1-31(2)45(53(71)72)62-52(70)44-30-74-73-29-43(60-46(64)32(3)55)51(69)59-40(26-33-12-6-4-7-13-33)49(67)58-41(27-34-17-21-37(22-18-34)36-14-8-5-9-15-36)48(66)56-39(16-10-11-25-54)47(65)57-42(50(68)61-44)28-35-19-23-38(63)24-20-35/h4-9,12-15,17-24,31-32,39-45,63H,10-11,16,25-30,54-55H2,1-3H3,(H,56,66)(H,57,65)(H,58,67)(H,59,69)(H,60,64)(H,61,68)(H,62,70)(H,71,72)/t32-,39-,40-,41+,42-,43-,44-,45-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Antagonist activity at human UT receptor expressed in HEK293 cells using Na [125I] incubated for 2 hrs by gamma counting method				ACS Med Chem Lett 11: 1717-1722 (2020) Article DOI: 10.1021/acsmedchemlett.0c00223 BindingDB Entry DOI: 10.7270/Q269775C
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302250 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-isopropylpi...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCNS(=O)(=O)c1cccs1)N1C(=O)c2cccc(N3CCN(CC3)C(C)C)c2C1=O |r| Show InChI InChI=1S/C31H38N4O6S2/c1-21(2)33-15-17-34(18-16-33)25-9-5-8-23-29(25)31(37)35(30(23)36)24(22-12-13-26(40-3)27(20-22)41-4)10-6-14-32-43(38,39)28-11-7-19-42-28/h5,7-9,11-13,19-21,24,32H,6,10,14-18H2,1-4H3/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50302272 (1-(2-(4-benzyl-4-hydroxypiperidin-1-yl)ethyl)-3-(2...) Show SMILES Cc1cc(NC(=O)NCCN2CCC(O)(Cc3ccccc3)CC2)c2ccccc2n1 Show InChI InChI=1S/C25H30N4O2/c1-19-17-23(21-9-5-6-10-22(21)27-19)28-24(30)26-13-16-29-14-11-25(31,12-15-29)18-20-7-3-2-4-8-20/h2-10,17,31H,11-16,18H2,1H3,(H2,26,27,28,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human urotensin 2 receptor				J Med Chem 53: 2695-708 (2010) Article DOI: 10.1021/jm901294u BindingDB Entry DOI: 10.7270/Q20G3K9N
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50459265 (CHEMBL4205274) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](Cc2ccc(I)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C50H63IN10O12S2/c1-26(2)42(50(72)73)61-49(71)40-25-75-74-24-39(59-43(65)33(53)22-41(63)64)48(70)57-36(19-27-10-14-30(51)15-11-27)45(67)58-38(21-29-23-54-34-8-4-3-7-32(29)34)47(69)55-35(9-5-6-18-52)44(66)56-37(46(68)60-40)20-28-12-16-31(62)17-13-28/h3-4,7-8,10-17,23,26,33,35-40,42,54,62H,5-6,9,18-22,24-25,52-53H2,1-2H3,(H,55,69)(H,56,66)(H,57,70)(H,58,67)(H,59,65)(H,60,68)(H,61,71)(H,63,64)(H,72,73)/t33-,35-,36-,37-,38-,39-,40-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [Na125I]-synthetic URP from human UT receptor expressed in HEK293 cell membranes incubated for 2 hrs by gamma-counting				J Med Chem 61: 8707-8716 (2018) Article DOI: 10.1021/acs.jmedchem.8b00789 BindingDB Entry DOI: 10.7270/Q2959M57
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302266 ((R)-N-(4-(4-(4-cyclobutylpiperazin-1-yl)-1-oxoisoi...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCN(C)S(=O)(=O)c1cccs1)N1Cc2c(cccc2N2CCN(CC2)C2CCC2)C1=O |r| Show InChI InChI=1S/C33H42N4O5S2/c1-34(44(39,40)32-13-7-21-43-32)16-6-12-28(24-14-15-30(41-2)31(22-24)42-3)37-23-27-26(33(37)38)10-5-11-29(27)36-19-17-35(18-20-36)25-8-4-9-25/h5,7,10-11,13-15,21-22,25,28H,4,6,8-9,12,16-20,23H2,1-3H3/t28-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302271 ((R)-2-(1-(3,4-dimethoxyphenyl)-4-(6-methoxypyrazin...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNc1cncc(OC)n1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H40N6O4/c1-5-35-14-16-36(17-15-35)26-9-6-8-23-24(26)21-37(31(23)38)25(22-11-12-27(39-2)28(18-22)40-3)10-7-13-33-29-19-32-20-30(34-29)41-4/h6,8-9,11-12,18-20,25H,5,7,10,13-17,21H2,1-4H3,(H,33,34)/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50252659 ((S)-N-(1-(3-bromo-4-(piperidin-4-yloxy)benzyl)pyrr...) Show SMILES Clc1ccc(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccc(OC3CCNCC3)c(Br)c2)C1 |r| Show InChI InChI=1S/C23H26BrCl2N3O2/c24-19-11-15(1-4-22(19)31-18-5-8-27-9-6-18)13-29-10-7-17(14-29)28-23(30)16-2-3-20(25)21(26)12-16/h1-4,11-12,17-18,27H,5-10,13-14H2,(H,28,30)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...				Bioorg Med Chem Lett 18: 3950-4 (2008) Article DOI: 10.1016/j.bmcl.2008.06.019 BindingDB Entry DOI: 10.7270/Q2FT8KTR
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302249 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N([C@H](CCCNS(=O)(=O)c3cccs3)c3ccc(OC)c(OC)c3)C(=O)c12 |r| Show InChI InChI=1S/C30H36N4O6S2/c1-4-32-15-17-33(18-16-32)24-9-5-8-22-28(24)30(36)34(29(22)35)23(21-12-13-25(39-2)26(20-21)40-3)10-6-14-31-42(37,38)27-11-7-19-41-27/h5,7-9,11-13,19-20,23,31H,4,6,10,14-18H2,1-3H3/t23-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445383 (CHEMBL3104471) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H64N10O10S2/c1-27(2)41(49(68)69)59-48(67)40-26-71-70-25-39(57-42(61)28(3)51)47(66)55-36(21-29-11-5-4-6-12-29)44(63)56-38(23-31-24-52-34-14-8-7-13-33(31)34)46(65)53-35(15-9-10-20-50)43(62)54-37(45(64)58-40)22-30-16-18-32(60)19-17-30/h4-8,11-14,16-19,24,27-28,35-41,52,60H,9-10,15,20-23,25-26,50-51H2,1-3H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,61)(H,58,64)(H,59,67)(H,68,69)/t28-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Antagonist activity at human UT receptor expressed in HEK293 cells using Na [125I] incubated for 2 hrs by gamma counting method				ACS Med Chem Lett 11: 1717-1722 (2020) Article DOI: 10.1021/acsmedchemlett.0c00223 BindingDB Entry DOI: 10.7270/Q269775C
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50459261 (CHEMBL4208184) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C55H68N10O10S2/c1-31(2)47(55(74)75)65-54(73)46-30-77-76-29-45(63-48(67)32(3)57)53(72)61-42(25-33-16-20-36(21-17-33)35-11-5-4-6-12-35)50(69)62-44(27-37-28-58-40-14-8-7-13-39(37)40)52(71)59-41(15-9-10-24-56)49(68)60-43(51(70)64-46)26-34-18-22-38(66)23-19-34/h4-8,11-14,16-23,28,31-32,41-47,58,66H,9-10,15,24-27,29-30,56-57H2,1-3H3,(H,59,71)(H,60,68)(H,61,72)(H,62,69)(H,63,67)(H,64,70)(H,65,73)(H,74,75)/t32-,41-,42-,43-,44-,45-,46-,47-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [Na125I]-synthetic URP from human UT receptor expressed in HEK293 cell membranes incubated for 2 hrs by gamma-counting				J Med Chem 61: 8707-8716 (2018) Article DOI: 10.1021/acs.jmedchem.8b00789 BindingDB Entry DOI: 10.7270/Q2959M57
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50459266 (CHEMBL4217514) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccc(I)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H63IN10O10S2/c1-26(2)41(49(69)70)60-48(68)40-25-72-71-24-39(58-42(62)27(3)52)47(67)56-36(20-28-11-15-31(50)16-12-28)44(64)57-38(22-30-23-53-34-9-5-4-8-33(30)34)46(66)54-35(10-6-7-19-51)43(63)55-37(45(65)59-40)21-29-13-17-32(61)18-14-29/h4-5,8-9,11-18,23,26-27,35-41,53,61H,6-7,10,19-22,24-25,51-52H2,1-3H3,(H,54,66)(H,55,63)(H,56,67)(H,57,64)(H,58,62)(H,59,65)(H,60,68)(H,69,70)/t27-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [Na125I]-synthetic URP from human UT receptor expressed in HEK293 cell membranes incubated for 2 hrs by gamma-counting				J Med Chem 61: 8707-8716 (2018) Article DOI: 10.1021/acs.jmedchem.8b00789 BindingDB Entry DOI: 10.7270/Q2959M57
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302268 (CHEMBL578206 | N-((R)-4-(3,4-dimethoxyphenyl)-4-(1...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCNC(=O)c1cnoc1C)N1Cc2c(cccc2N2CCN(CC2)[C@H](C)c2ccccc2)C1=O |r| Show InChI InChI=1S/C37H43N5O5/c1-25(27-10-6-5-7-11-27)40-18-20-41(21-19-40)33-13-8-12-29-31(33)24-42(37(29)44)32(28-15-16-34(45-3)35(22-28)46-4)14-9-17-38-36(43)30-23-39-47-26(30)2/h5-8,10-13,15-16,22-23,25,32H,9,14,17-21,24H2,1-4H3,(H,38,43)/t25-,32-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302260 ((R)-2-(1-(3,4-dimethoxyphenyl)-4-(thiophen-2-ylmet...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNCc1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H40N4O3S/c1-4-33-15-17-34(18-16-33)28-10-5-9-25-26(28)22-35(31(25)36)27(11-6-14-32-21-24-8-7-19-39-24)23-12-13-29(37-2)30(20-23)38-3/h5,7-10,12-13,19-20,27,32H,4,6,11,14-18,21-22H2,1-3H3/t27-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50508365 (CHEMBL4457118) Show SMILES Fc1ccc(cc1F)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C27H28ClF2N3O3/c28-21-15-18(1-4-25(21)35-20-7-9-31-10-8-20)17-32-11-13-33(14-12-32)27(34)26-6-5-24(36-26)19-2-3-22(29)23(30)16-19/h1-6,15-16,20,31H,7-14,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058 BindingDB Entry DOI: 10.7270/Q2445QS4
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50249878 ((R)-2-bromo-4,5-dimethoxy-N-(3-(1-methylpyrrolidin...) Show SMILES COc1cc(Br)c(cc1OC)S(=O)(=O)Nc1ccc(c(O[C@@H]2CCN(C)C2)c1)C(F)(F)F |r| Show InChI InChI=1S/C20H22BrF3N2O5S/c1-26-7-6-13(11-26)31-16-8-12(4-5-14(16)20(22,23)24)25-32(27,28)19-10-18(30-3)17(29-2)9-15(19)21/h4-5,8-10,13,25H,6-7,11H2,1-3H3/t13-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [125I]-U2 from human recombinant urotensin2 receptor expressed in human Chem-2 cells after 4 hrs by scintillation proximity assay				Bioorg Med Chem Lett 23: 2177-80 (2013) Article DOI: 10.1016/j.bmcl.2013.01.105 BindingDB Entry DOI: 10.7270/Q2XS5WSW
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302259 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNC(=O)c1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H38N4O4S/c1-4-33-15-17-34(18-16-33)26-9-5-8-23-24(26)21-35(31(23)37)25(22-12-13-27(38-2)28(20-22)39-3)10-6-14-32-30(36)29-11-7-19-40-29/h5,7-9,11-13,19-20,25H,4,6,10,14-18,21H2,1-3H3,(H,32,36)/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302261 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCN(C)S(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C31H40N4O5S2/c1-5-33-16-18-34(19-17-33)27-10-6-9-24-25(27)22-35(31(24)36)26(23-13-14-28(39-3)29(21-23)40-4)11-7-15-32(2)42(37,38)30-12-8-20-41-30/h6,8-10,12-14,20-21,26H,5,7,11,15-19,22H2,1-4H3/t26-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50543461 (CHEMBL4638346) Show SMILES [H][C@]1(CSSC[C@]([H])(NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(OCc3ccccc3)cc2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C54H69N9O11S2/c1-32(2)46(54(72)73)63-53(71)45-31-76-75-30-44(61-47(65)33(3)56)52(70)60-41(26-34-12-6-4-7-13-34)50(68)59-42(28-36-19-23-39(24-20-36)74-29-37-14-8-5-9-15-37)49(67)57-40(16-10-11-25-55)48(66)58-43(51(69)62-45)27-35-17-21-38(64)22-18-35/h4-9,12-15,17-24,32-33,40-46,64H,10-11,16,25-31,55-56H2,1-3H3,(H,57,67)(H,58,66)(H,59,68)(H,60,70)(H,61,65)(H,62,69)(H,63,71)(H,72,73)/t33-,40-,41-,42-,43-,44-,45-,46-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Antagonist activity at human UT receptor expressed in HEK293 cells using Na [125I] incubated for 2 hrs by gamma counting method				ACS Med Chem Lett 11: 1717-1722 (2020) Article DOI: 10.1021/acsmedchemlett.0c00223 BindingDB Entry DOI: 10.7270/Q269775C
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50302257 ((R)-N-(4-(3,4-dimethoxyphenyl)-4-(4-(4-ethylpipera...) Show SMILES CCN1CCN(CC1)c1cccc2C(=O)N(Cc12)[C@H](CCCNS(=O)(=O)c1cccs1)c1ccc(OC)c(OC)c1 |r| Show InChI InChI=1S/C30H38N4O5S2/c1-4-32-15-17-33(18-16-32)26-9-5-8-23-24(26)21-34(30(23)35)25(22-12-13-27(38-2)28(20-22)39-3)10-6-14-31-41(36,37)29-11-7-19-40-29/h5,7-9,11-13,19-20,25,31H,4,6,10,14-18,21H2,1-3H3/t25-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50249878 ((R)-2-bromo-4,5-dimethoxy-N-(3-(1-methylpyrrolidin...) Show SMILES COc1cc(Br)c(cc1OC)S(=O)(=O)Nc1ccc(c(O[C@@H]2CCN(C)C2)c1)C(F)(F)F |r| Show InChI InChI=1S/C20H22BrF3N2O5S/c1-26-7-6-13(11-26)31-16-8-12(4-5-14(16)20(22,23)24)25-32(27,28)19-10-18(30-3)17(29-2)9-15(19)21/h4-5,8-10,13,25H,6-7,11H2,1-3H3/t13-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at urotensin 2 receptor in human RMS13 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobilization aft...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445376 (CHEMBL3104644) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2Cc3[nH]c4ccccc4c3C[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C50H64N10O10S2/c1-27(2)42(50(69)70)59-47(66)40-26-72-71-25-39(57-43(62)28(3)52)46(65)56-37(22-29-11-5-4-6-12-29)49(68)60-24-38-33(32-13-7-8-14-34(32)53-38)23-41(60)48(67)54-35(15-9-10-20-51)44(63)55-36(45(64)58-40)21-30-16-18-31(61)19-17-30/h4-8,11-14,16-19,27-28,35-37,39-42,53,61H,9-10,15,20-26,51-52H2,1-3H3,(H,54,67)(H,55,63)(H,56,65)(H,57,62)(H,58,64)(H,59,66)(H,69,70)/t28-,35-,36-,37-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445376 (CHEMBL3104644) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2Cc3[nH]c4ccccc4c3C[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C50H64N10O10S2/c1-27(2)42(50(69)70)59-47(66)40-26-72-71-25-39(57-43(62)28(3)52)46(65)56-37(22-29-11-5-4-6-12-29)49(68)60-24-38-33(32-13-7-8-14-34(32)53-38)23-41(60)48(67)54-35(15-9-10-20-51)44(63)55-36(45(64)58-40)21-30-16-18-31(61)19-17-30/h4-8,11-14,16-19,27-28,35-37,39-42,53,61H,9-10,15,20-26,51-52H2,1-3H3,(H,54,67)(H,55,63)(H,56,65)(H,57,62)(H,58,64)(H,59,66)(H,69,70)/t28-,35-,36-,37-,39-,40-,41-,42-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50508375 (CHEMBL4525919) Show SMILES Fc1cccc(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C27H29ClFN3O3/c28-23-16-19(4-5-25(23)34-22-8-10-30-11-9-22)18-31-12-14-32(15-13-31)27(33)26-7-6-24(35-26)20-2-1-3-21(29)17-20/h1-7,16-17,22,30H,8-15,18H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058 BindingDB Entry DOI: 10.7270/Q2445QS4
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50224715 (CHEMBL396443 | tert-butyl 4-(2-(5-chloro-2-(1-(2-(...) Show SMILES CC(C)(C)OC(=O)N1CCN(CCNC(=O)c2cc(Cl)ccc2C2CCN(CCN3C(=O)COc4ccccc34)CC2)CC1 Show InChI InChI=1S/C33H44ClN5O5/c1-33(2,3)44-32(42)38-19-16-37(17-20-38)15-12-35-31(41)27-22-25(34)8-9-26(27)24-10-13-36(14-11-24)18-21-39-28-6-4-5-7-29(28)43-23-30(39)40/h4-9,22,24H,10-21,23H2,1-3H3,(H,35,41)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Antagonist activity at rat UT receptor transfected in CHOK1 cells assessed as calcium mobilization by FLIPR method				Bioorg Med Chem Lett 17: 6489-92 (2007) Article DOI: 10.1016/j.bmcl.2007.09.092 BindingDB Entry DOI: 10.7270/Q2C53KKJ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445370 (CHEMBL3104464) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCc3ccccc3[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C48H63N9O10S2/c1-27(2)39(48(66)67)56-45(63)38-26-69-68-25-37(54-41(59)28(3)50)44(62)53-36(24-29-11-5-4-6-12-29)47(65)57-22-20-31-13-7-8-14-33(31)40(57)46(64)51-34(15-9-10-21-49)42(60)52-35(43(61)55-38)23-30-16-18-32(58)19-17-30/h4-8,11-14,16-19,27-28,34-40,58H,9-10,15,20-26,49-50H2,1-3H3,(H,51,64)(H,52,60)(H,53,62)(H,54,59)(H,55,61)(H,56,63)(H,66,67)/t28-,34-,35-,36-,37-,38-,39-,40-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445370 (CHEMBL3104464) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCc3ccccc3[C@H]2C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C48H63N9O10S2/c1-27(2)39(48(66)67)56-45(63)38-26-69-68-25-37(54-41(59)28(3)50)44(62)53-36(24-29-11-5-4-6-12-29)47(65)57-22-20-31-13-7-8-14-33(31)40(57)46(64)51-34(15-9-10-21-49)42(60)52-35(43(61)55-38)23-30-16-18-32(58)19-17-30/h4-8,11-14,16-19,27-28,34-40,58H,9-10,15,20-26,49-50H2,1-3H3,(H,51,64)(H,52,60)(H,53,62)(H,54,59)(H,55,61)(H,56,63)(H,66,67)/t28-,34-,35-,36-,37-,38-,39-,40-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302252 (CHEMBL568764 | N-((R)-4-(3,4-dimethoxyphenyl)-4-(1...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCNC(=O)c1cnoc1C)N1C(=O)c2cccc(N3CCN(CC3)[C@H](C)c3ccccc3)c2C1=O |r| Show InChI InChI=1S/C37H41N5O6/c1-24(26-10-6-5-7-11-26)40-18-20-41(21-19-40)31-13-8-12-28-34(31)37(45)42(36(28)44)30(27-15-16-32(46-3)33(22-27)47-4)14-9-17-38-35(43)29-23-39-48-25(29)2/h5-8,10-13,15-16,22-24,30H,9,14,17-21H2,1-4H3,(H,38,43)/t24-,30-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302254 (CHEMBL565388 | N-((R)-4-(3,4-dimethoxyphenyl)-4-(1...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCNC(=O)c1c(C)n[nH]c1C)N1C(=O)c2cccc(N3CCN(CC3)[C@H](C)c3ccccc3)c2C1=O |r| Show InChI InChI=1S/C38H44N6O5/c1-24-34(25(2)41-40-24)36(45)39-18-10-15-30(28-16-17-32(48-4)33(23-28)49-5)44-37(46)29-13-9-14-31(35(29)38(44)47)43-21-19-42(20-22-43)26(3)27-11-7-6-8-12-27/h6-9,11-14,16-17,23,26,30H,10,15,18-22H2,1-5H3,(H,39,45)(H,40,41)/t26-,30-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (RAT)	BDBM50302253 (CHEMBL567759 | N-((R)-4-(3,4-dimethoxyphenyl)-4-(1...) Show SMILES COc1ccc(cc1OC)[C@@H](CCCNS(=O)(=O)c1c(C)n[nH]c1C)N1C(=O)c2cccc(N3CCN(CC3)[C@H](C)c3ccccc3)c2C1=O |r| Show InChI InChI=1S/C37H44N6O6S/c1-24-35(25(2)40-39-24)50(46,47)38-18-10-15-30(28-16-17-32(48-4)33(23-28)49-5)43-36(44)29-13-9-14-31(34(29)37(43)45)42-21-19-41(20-22-42)26(3)27-11-7-6-8-12-27/h6-9,11-14,16-17,23,26,30,38H,10,15,18-22H2,1-5H3,(H,39,40)/t26-,30-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Antagonist activity at rat urotensin 2 receptor expressed in CHOK1 cells assessed as inhibition of urotensin 2-induced intracellular calcium mobiliza...				J Med Chem 52: 7432-45 (2009) Article DOI: 10.1021/jm900683d BindingDB Entry DOI: 10.7270/Q2S75GD7
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50543459 (CHEMBL4643905) Show SMILES [H][C@]1(CSSC[C@]([H])(NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@H](Cc2ccc(cc2)C#Cc2ccccc2)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(=O)N[C@@H](C(C)C)C(O)=O |r| Show InChI InChI=1S/C55H67N9O10S2/c1-33(2)47(55(73)74)64-54(72)46-32-76-75-31-45(62-48(66)34(3)57)53(71)61-42(28-37-14-8-5-9-15-37)51(69)60-43(29-38-21-19-36(20-22-38)18-17-35-12-6-4-7-13-35)50(68)58-41(16-10-11-27-56)49(67)59-44(52(70)63-46)30-39-23-25-40(65)26-24-39/h4-9,12-15,19-26,33-34,41-47,65H,10-11,16,27-32,56-57H2,1-3H3,(H,58,68)(H,59,67)(H,60,69)(H,61,71)(H,62,66)(H,63,70)(H,64,72)(H,73,74)/t34-,41-,42-,43+,44-,45-,46-,47-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Antagonist activity at human UT receptor expressed in HEK293 cells using Na [125I] incubated for 2 hrs by gamma counting method				ACS Med Chem Lett 11: 1717-1722 (2020) Article DOI: 10.1021/acsmedchemlett.0c00223 BindingDB Entry DOI: 10.7270/Q269775C
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50445383 (CHEMBL3104471) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](C)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O |r| Show InChI InChI=1S/C49H64N10O10S2/c1-27(2)41(49(68)69)59-48(67)40-26-71-70-25-39(57-42(61)28(3)51)47(66)55-36(21-29-11-5-4-6-12-29)44(63)56-38(23-31-24-52-34-14-8-7-13-33(31)34)46(65)53-35(15-9-10-20-50)43(62)54-37(45(64)58-40)22-30-16-18-32(60)19-17-30/h4-8,11-14,16-19,24,27-28,35-41,52,60H,9-10,15,20-23,25-26,50-51H2,1-3H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,61)(H,58,64)(H,59,67)(H,68,69)/t28-,35-,36-,37-,38-,39-,40-,41-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50378580 (CHEMBL437430) Show SMILES CC(C)[C@H](NC(=O)[C@@H]1CSSC[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](N)CCC(O)=O)[C@@H](C)O)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N1)C(O)=O Show InChI InChI=1S/C64H85N13O18S2/c1-33(2)52(64(94)95)75-61(91)48-32-97-96-31-47(73-59(89)46(29-51(82)83)72-62(92)49-17-11-25-77(49)63(93)53(34(3)78)76-54(84)40(66)22-23-50(80)81)60(90)70-43(26-35-12-5-4-6-13-35)56(86)71-45(28-37-30-67-41-15-8-7-14-39(37)41)58(88)68-42(16-9-10-24-65)55(85)69-44(57(87)74-48)27-36-18-20-38(79)21-19-36/h4-8,12-15,18-21,30,33-34,40,42-49,52-53,67,78-79H,9-11,16-17,22-29,31-32,65-66H2,1-3H3,(H,68,88)(H,69,85)(H,70,90)(H,71,86)(H,72,92)(H,73,89)(H,74,87)(H,75,91)(H,76,84)(H,80,81)(H,82,83)(H,94,95)/t34-,40+,42-,43-,44+,45+,46+,47-,48+,49-,52+,53+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ du Qu£bec Curated by ChEMBL					Assay Description Displacement of [125I]-Urotensin-2 from human GPR14 expressed in CHO cells after 90 mins by gamma counting analysis				J Med Chem 56: 9612-22 (2014) Article DOI: 10.1021/jm401153j BindingDB Entry DOI: 10.7270/Q2TD9ZTZ
					More data for this Ligand-Target Pair
Urotensin-2 receptor (Homo sapiens (Human))	BDBM50036148 (CHEMBL3358687) Show SMILES OC1(Cc2ccc(F)cc2)CCN(CCNC(=O)Nc2ccnc3ccsc23)CC1 Show InChI InChI=1S/C22H25FN4O2S/c23-17-3-1-16(2-4-17)15-22(29)7-11-27(12-8-22)13-10-25-21(28)26-19-5-9-24-18-6-14-30-20(18)19/h1-6,9,14,29H,7-8,10-13,15H2,(H2,24,25,26,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of europium-labeled urotensin-II from human urotensin-2 receptor expressed in HEK293 cells by TRF assay				Bioorg Med Chem Lett 24: 5832-5 (2014) Article DOI: 10.1016/j.bmcl.2014.09.089 BindingDB Entry DOI: 10.7270/Q2H133M2
					More data for this Ligand-Target Pair

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