Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article | 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay | Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50280009 (CHEMBL88059 | N-((S)-1,2,3-Trimethoxy-10-methylami...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay | Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50280140 (CHEMBL418565 | [6-(3,4,5-Trimethoxy-benzyloxy)-imi...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article | 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for competitive inhibition with radioligand [3H]colchicine at colchicine site of mammalian tubulin | Bioorg Med Chem Lett 2: 1257-1262 (1992) Article DOI: 10.1016/S0960-894X(00)80225-5 BindingDB Entry DOI: 10.7270/Q25X29DB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay | Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50280008 (2-Methylamino-5-(2,3,4-trimethoxy-phenyl)-cyclohep...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay | Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50279934 (2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay | Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50280007 (2-Methylsulfanyl-5-(2,3,4-trimethoxy-phenyl)-cyclo...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay | Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92 | |||||||||||
More data for this Ligand-Target Pair |