Compile Data Set for Download or QSAR

Found 31 hits of ic50 for UniProtKB: P0A6I6   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82156 (7-substituted pyrazoloquinolone, 15) Show SMILES CC(C)Sc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C14H13N3O3S/c1-7(2)21-8-3-4-10-9(5-8)13(18)17-12(15-10)6-11(16-17)14(19)20/h3-7,16H,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82152 (7-substituted pyrazoloquinolone, 11) Show SMILES OC(=O)c1cc2nc3ccc(I)cc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6IN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM50517256 (CHEMBL4446301) Show SMILES OC(=O)c1cc2[nH]c3ccc(Br)cc3c(=O)n2n1 Show InChI InChI=1S/C11H6BrN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,13H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lavis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli PPAT after 5 mins by reverse ATP-generating-luciferase assay				J Med Chem 62: 2218-2244 (2019) Article DOI: 10.1021/acs.jmedchem.8b01210 BindingDB Entry DOI: 10.7270/Q2BP065B
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82151 (7-substituted pyrazoloquinolone, 10) Show SMILES OC(=O)c1cc2nc3ccc(Br)cc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6BrN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82157 (7-substituted pyrazoloquinolone, 16) Show SMILES CN(C)c1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C13H12N4O3/c1-16(2)7-3-4-9-8(5-7)12(18)17-11(14-9)6-10(15-17)13(19)20/h3-6,15H,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82153 (7-substituted pyrazoloquinolone, 12) Show SMILES CSc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C12H9N3O3S/c1-19-6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82152 (7-substituted pyrazoloquinolone, 11) Show SMILES OC(=O)c1cc2nc3ccc(I)cc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6IN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82153 (7-substituted pyrazoloquinolone, 12) Show SMILES CSc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C12H9N3O3S/c1-19-6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82156 (7-substituted pyrazoloquinolone, 15) Show SMILES CC(C)Sc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C14H13N3O3S/c1-7(2)21-8-3-4-10-9(5-8)13(18)17-12(15-10)6-11(16-17)14(19)20/h3-7,16H,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82160 (6-substituted pyrazoloquinolone, 19) Show SMILES Cc1ccc2c(c1)nc1cc([nH]n1c2=O)C(O)=O Show InChI InChI=1S/C12H9N3O3/c1-6-2-3-7-8(4-6)13-10-5-9(12(17)18)14-15(10)11(7)16/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82149 (7-substituted pyrazoloquinolone, 8) Show SMILES OC(=O)c1cc2nc3ccc(Cl)cc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6ClN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82151 (7-substituted pyrazoloquinolone, 10) Show SMILES OC(=O)c1cc2nc3ccc(Br)cc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6BrN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82157 (7-substituted pyrazoloquinolone, 16) Show SMILES CN(C)c1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C13H12N4O3/c1-16(2)7-3-4-9-8(5-7)12(18)17-11(14-9)6-10(15-17)13(19)20/h3-6,15H,1-2H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82164 (6-substituted pyrazoloquinolone, 23) Show SMILES OC(=O)c1cc2nc3cc(Cl)ccc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6ClN3O3/c12-5-1-2-6-7(3-5)13-9-4-8(11(17)18)14-15(9)10(6)16/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82161 (6-substituted pyrazoloquinolone, 20) Show SMILES OC(=O)c1cc2nc3cc(ccc3c(=O)n2[nH]1)C(F)(F)F Show InChI InChI=1S/C12H6F3N3O3/c13-12(14,15)5-1-2-6-7(3-5)16-9-4-8(11(20)21)17-18(9)10(6)19/h1-4,17H,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82155 (7-substituted pyrazoloquinolone, 14) Show SMILES CS(=O)(=O)c1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C12H9N3O5S/c1-21(19,20)6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82164 (6-substituted pyrazoloquinolone, 23) Show SMILES OC(=O)c1cc2nc3cc(Cl)ccc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6ClN3O3/c12-5-1-2-6-7(3-5)13-9-4-8(11(17)18)14-15(9)10(6)16/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM50517257 (CHEMBL4584904) Show SMILES FC(F)(F)C(=O)NCCOc1cccc(Cl)c1 Show InChI InChI=1S/C10H9ClF3NO2/c11-7-2-1-3-8(6-7)17-5-4-15-9(16)10(12,13)14/h1-3,6H,4-5H2,(H,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lavis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli PPAT after 5 mins by reverse ATP-generating-luciferase assay				J Med Chem 62: 2218-2244 (2019) Article DOI: 10.1021/acs.jmedchem.8b01210 BindingDB Entry DOI: 10.7270/Q2BP065B
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM50517254 (CHEMBL4553617) Show SMILES COc1ccc2nc(oc(=O)c2c1)C(F)(F)F Show InChI InChI=1S/C10H6F3NO3/c1-16-5-2-3-7-6(4-5)8(15)17-9(14-7)10(11,12)13/h2-4H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lavis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli PPAT after 5 mins by reverse ATP-generating-luciferase assay				J Med Chem 62: 2218-2244 (2019) Article DOI: 10.1021/acs.jmedchem.8b01210 BindingDB Entry DOI: 10.7270/Q2BP065B
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82150 (7-substituted pyrazoloquinolone, 9) Show SMILES OC(=O)c1cc2nc3ccc(F)cc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6FN3O3/c12-5-1-2-7-6(3-5)10(16)15-9(13-7)4-8(14-15)11(17)18/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82165 (3-substituted pyrazoloquinolone, 24) Show SMILES Cc1c([nH]n2c1nc1cc(Cl)ccc1c2=O)C(O)=O Show InChI InChI=1S/C12H8ClN3O3/c1-5-9(12(18)19)15-16-10(5)14-8-4-6(13)2-3-7(8)11(16)17/h2-4,15H,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82162 (6-substituted pyrazoloquinolone, 21) Show SMILES Nc1ccc2c(c1)nc1cc([nH]n1c2=O)C(O)=O Show InChI InChI=1S/C11H8N4O3/c12-5-1-2-6-7(3-5)13-9-4-8(11(17)18)14-15(9)10(6)16/h1-4,14H,12H2,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82163 (6-substituted pyrazoloquinolone, 22) Show SMILES OC(=O)c1cc2nc3cc(Br)ccc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6BrN3O3/c12-5-1-2-6-7(3-5)13-9-4-8(11(17)18)14-15(9)10(6)16/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82163 (6-substituted pyrazoloquinolone, 22) Show SMILES OC(=O)c1cc2nc3cc(Br)ccc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H6BrN3O3/c12-5-1-2-6-7(3-5)13-9-4-8(11(17)18)14-15(9)10(6)16/h1-4,14H,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82158 (7-substituted pyrazoloquinolone, 17) Show SMILES COc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C12H9N3O4/c1-19-6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82159 (4-substituted pyrazoloquinolone, 18) Show SMILES Cn1c2cc(nn2c(=O)c2cc(Cl)ccc12)C(O)=O Show InChI InChI=1S/C12H8ClN3O3/c1-15-9-3-2-6(13)4-7(9)11(17)16-10(15)5-8(14-16)12(18)19/h2-5H,1H3,(H,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82154 (7-substituted pyrazoloquinolone, 13) Show SMILES CS(=O)c1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C12H9N3O4S/c1-20(19)6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.66E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82161 (6-substituted pyrazoloquinolone, 20) Show SMILES OC(=O)c1cc2nc3cc(ccc3c(=O)n2[nH]1)C(F)(F)F Show InChI InChI=1S/C12H6F3N3O3/c13-12(14,15)5-1-2-6-7(3-5)16-9-4-8(11(20)21)17-18(9)10(6)19/h1-4,17H,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82147 (7-substituted pyrazoloquinolone, 6) Show SMILES OC(=O)c1cc2nc3ccccc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H7N3O3/c15-10-6-3-1-2-4-7(6)12-9-5-8(11(16)17)13-14(9)10/h1-5,13H,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description The reverse assay was performed in polyproplene 96-well plates containing in each well either 1 uL DMSO, 1 UL of variable concentrations of test comp...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82148 (7-substituted pyrazoloquinolone, 7) Show SMILES Cc1ccc2nc3cc([nH]n3c(=O)c2c1)C(O)=O Show InChI InChI=1S/C12H9N3O3/c1-6-2-3-8-7(4-6)11(16)15-10(13-8)5-9(14-15)12(17)18/h2-5,14H,1H3,(H,17,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair
Phosphopantetheine adenylyltransferase (Escherichia coli)	BDBM82147 (7-substituted pyrazoloquinolone, 6) Show SMILES OC(=O)c1cc2nc3ccccc3c(=O)n2[nH]1 Show InChI InChI=1S/C11H7N3O3/c15-10-6-3-1-2-4-7(6)12-9-5-8(11(16)17)13-14(9)10/h1-5,13H,(H,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.53E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer, Inc.					Assay Description PPAT screening assay (forward-direction assay) were performed in clear 384 well plates containing in each well either 1-uL DMSO, 1 uL of variable con...				Chem Biol Drug Des 75: 444-54 (2010) Article DOI: 10.1111/j.1747-0285.2010.00957.x BindingDB Entry DOI: 10.7270/Q2765CT2
					More data for this Ligand-Target Pair